2,3-Bis(3,4-dihydroxyphenyl)butanedioic acid (BioDeep_00000177311)

   

human metabolite blood metabolite


代谢物信息卡片


2,3-Bis(3,4-dihydroxyphenyl)butanedioic acid

化学式: C16H14O8 (334.0689)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: C1=CC(=C(C=C1C(C(C2=CC(=C(C=C2)O)O)C(=O)O)C(=O)O)O)O
InChI: InChI=1S/C16H14O8/c17-9-3-1-7(5-11(9)19)13(15(21)22)14(16(23)24)8-2-4-10(18)12(20)6-8/h1-6,13-14,17-20H,(H,21,22)(H,23,24)

描述信息

同义名列表

2 个代谢物同义名

2,3-Bis(3,4-dihydroxyphenyl)butanedioic acid; 2,3-Bis(3,4-dihydroxyphenyl)butanedioate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Georg Nikisch, Pierre Baumann, Bernhard Kiessling, Michael Reinert, Georg Wiedemann, Jan Kehr, Aleksander A Mathé, Markus Piel, Frank Roesch, Heike Weisser, Peter Schneider, Andreas Hertel. Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine. Journal of psychiatric research. 2010 Sep; 44(12):754-9. doi: 10.1016/j.jpsychires.2010.02.004. [PMID: 20176367]
  • Maaike M Appeldoorn, Jean-Paul Vincken, Anna-Marja Aura, Peter C H Hollman, Harry Gruppen. Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-gamma-valerolactone as the major metabolites. Journal of agricultural and food chemistry. 2009 Feb; 57(3):1084-92. doi: 10.1021/jf803059z. [PMID: 19191673]
  • Alegría Carrasco-Pancorbo, Lorenzo Cerretani, Alessandra Bendini, Antonio Segura-Carretero, Giovanni Lercker, Alberto Fernández-Gutiérrez. Evaluation of the influence of thermal oxidation on the phenolic composition and on the antioxidant activity of extra-virgin olive oils. Journal of agricultural and food chemistry. 2007 Jun; 55(12):4771-80. doi: 10.1021/jf070186m. [PMID: 17497881]
  • Kurt Rasmussen, Mark J Benvenga, Frank P Bymaster, David O Calligaro, Ilene R Cohen, Julie F Falcone, Susan K Hemrick-Luecke, Fionna M Martin, Nicholas A Moore, Laura K Nisenbaum, John M Schaus, Sarah J Sundquist, David E Tupper, Todd R Wiernicki, David L Nelson. Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: a potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine. The Journal of pharmacology and experimental therapeutics. 2005 Dec; 315(3):1265-77. doi: 10.1124/jpet.105.089326. [PMID: 16141369]
  • Jae Yeol Lee, Kwon Joong Yoon, Yong Sup Lee. Catechol-substituted L-chicoric acid analogues as HIV integrase inhibitors. Bioorganic & medicinal chemistry letters. 2003 Dec; 13(24):4331-4. doi: 10.1016/j.bmcl.2003.09.046. [PMID: 14643320]
  • Sami Ojanen, Meri Koistinen, Pia Bäckström, Aino Kankaanpää, Päivi Tuomainen, Petri Hyytiä, Kalervo Kiianmaa. Differential behavioural sensitization to intermittent morphine treatment in alcohol-preferring AA and alcohol-avoiding ANA rats: role of mesolimbic dopamine. The European journal of neuroscience. 2003 Apr; 17(8):1655-63. doi: 10.1046/j.1460-9568.2003.02589.x. [PMID: 12752383]
  • Xiaosuo Wang, George A Smythe. Assessment of hydroxyl radical generation and radical scavenging activity of Chinese medicinal herbs using GC-MS. Redox report : communications in free radical research. 2003; 8(4):223-8. doi: 10.1179/135100003225002727. [PMID: 14599346]
  • Giuseppe Battaglia, Francesco Fornai, Carla L Busceti, Gabriella Aloisi, Franca Cerrito, Antonio De Blasi, Daniela Melchiorri, Ferdinando Nicoletti. Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Mar; 22(6):2135-41. doi: 10.1523/jneurosci.22-06-02135.2002. [PMID: 11896153]
  • M V Selikhova, B M Kogan, G V Serkin, E I Gusev. [Catecholamine metabolism in different forms of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2002; 102(9):37-40. doi: NULL. [PMID: 12378880]
  • V Raneva, H Shimasaki, Y Ishida, N Ueta, E Niki. Antioxidative activity of 3,4-dihydroxyphenylacetic acid and caffeic acid in rat plasma. Lipids. 2001 Oct; 36(10):1111-6. doi: 10.1007/s11745-001-0821-6. [PMID: 11768155]
  • J A Del Compare, J A Aguirre, F R Ibarra, M Barontini, I Armando. Effects of thyroid hormone on the renal dopaminergic system. Endocrine. 2001 Aug; 15(3):297-303. doi: 10.1385/endo:15:3:297. [PMID: 11762703]
  • N Serdarevic, G P Eckert, W E Müller. The effects of extracts from St. John's Wort and Kava Kava on brain neurotransmitter levels in the mouse. Pharmacopsychiatry. 2001 Jul; 34 Suppl 1(?):S134-6. doi: 10.1055/s-2001-15463. [PMID: 11518062]
  • K Shieh, J Pan. Effects of orphanin FQ on central dopaminergic neuronal activities and prolactin secretion. American journal of physiology. Regulatory, integrative and comparative physiology. 2001 Mar; 280(3):R705-12. doi: 10.1152/ajpregu.2001.280.3.r705. [PMID: 11171648]
  • H K Wayment, J O Schenk, B A Sorg. Characterization of extracellular dopamine clearance in the medial prefrontal cortex: role of monoamine uptake and monoamine oxidase inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2001 Jan; 21(1):35-44. doi: . [PMID: 11150317]