Exact Mass: 313.0674

5'-Phosphoribosyl-N-formylglycinamidine

[(2R,3S,4R,5R)-5-[(Z)-(1-amino-2-formamidoethylidene)amino]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

C8H16N3O8P (313.0675)

5-Phosphoribosyl-N-formylglycinamidine, also known as FGAM or phosphoribosylformylglycinamidine, belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. FGAM is a very strong basic compound (based on its pKa). Within humans, FGAM participates in several enzymatic reactions. FGAM is an intermediate in purine metabolism and it can be biosynthesized (along with L-glutamic acid) from 5-phosphoribosyl-N-formylglycinamide (FGAR) and L-glutamine. This reaction is catalyzed by the enzyme phosphoribosylformylglycinamidine synthase (EC 6.3.5.3). Additionally, FGAM can be converted into aminoimidazole ribotide (AIR) through its interaction with the enzyme trifunctional purine biosynthetic protein adenosine-3 (EC 6.3.3.1). Outside of the human body, FGAM has been detected, but not quantified in, several different foods, such as Welsh onions, green beans, chicories, European cranberries, and Mexican oregano. This could make FGAM a potential biomarker for the consumption of these foods. 5-Phosphoribosyl-n-formylglycineamidine is a substrate for Glucosamine-6-phosphate isomerase. [HMDB]. Phosphoribosylformylglycineamidine is found in many foods, some of which are greenthread tea, cardamom, mulberry, and carrot. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

Melicopine

1,3-Dioxolo[4,5-c]acridin-6(11H)-one,4,5-dimethoxy-11-methyl-

Karphos

ISOXATHION

C13H16NO4PS (313.0538)

CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9696; ORIGINAL_PRECURSOR_SCAN_NO 9695 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9735; ORIGINAL_PRECURSOR_SCAN_NO 9730 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9644; ORIGINAL_PRECURSOR_SCAN_NO 9642 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9682; ORIGINAL_PRECURSOR_SCAN_NO 9680 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9725; ORIGINAL_PRECURSOR_SCAN_NO 9724 CONFIDENCE standard compound; INTERNAL_ID 790; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9709; ORIGINAL_PRECURSOR_SCAN_NO 9708

Chlorozotocin

D-Glucose, 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-2-deoxy-

C9H16ClN3O7 (313.0677)

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D002273 - Carcinogens D000970 - Antineoplastic Agents

Amoxapine

13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3,5,7,9,12,14-heptaene

Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation. In depressed individuals, amoxapine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine H₁ receptors, α₁-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Amoxapine may be used to treat neurotic and reactive depressive disorders, endogenous and psychotic depression, and mixed symptoms of depression and anxiety or agitation. N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AA - Non-selective monoamine reuptake inhibitors D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent > C94727 - Tricyclic Antidepressant D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D049990 - Membrane Transport Modulators

Flunitrazepam

5-(O-Fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one

A benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug. [PubChem] N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CD - Benzodiazepine derivatives D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent

Phosphoribosylformylglycinamidine

{[(2R,3S,4R,5R)-5-[N-(carbamimidoylmethyl)formamido]-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

C8H16N3O8P (313.0675)

Phosphoribosylformylglycinamidine, also known as formylglycinamidine ribonucleotide (FGAM), is a substrate for glucosamine-6-phosphate isomerase. Phosphoribosylformylglycinamidine is found in many foods, some of which are greenthread tea, cardamom, mulberry, and carrot. 5-Phosphoribosyl-n-formylglycineamidine is a substrate for Glucosamine-6-phosphate isomerase. [HMDB]. Phosphoribosylformylglycineamidine is found in many foods, some of which are greenthread tea, cardamom, mulberry, and carrot. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

(S)-5'-Deoxy-5'-(methylsulfinyl)adenosine

2-(6-Amino-9H-purin-9-yl)-5-(methanesulphinylmethyl)oxolane-3,4-diol

C11H15N5O4S (313.0845)

(S)-5-Deoxy-5-(methylsulfinyl)adenosine is found in mushrooms. (S)-5-Deoxy-5-(methylsulfinyl)adenosine is produced by Ganoderma lucidum (reishi). Production by Ganoderma lucidum (reishi). (R)-5-Deoxy-5-(methylsulfinyl)adenosine is found in mushrooms.

Avenanthramide 1f

2-{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino}benzoate

Avenanthramide 1f is a polyphenol compound found in foods of plant origin (PMID: 20428313)

Tyramine glucuronide

(2S,3S,4S,5R,6S)-6-[4-(2-aminoethyl)phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

Tyramine glucuronide is a natural human metabolite of Tyramine generated in the liver by UDP glucuonyltransferase. Glucuronidation is used to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys. Tyramine glucuronide is a natural human metabolite of Tyramine generated in the liver by UDP glucuonyltransferase.

Avenanthramide E

2-{[(2Z)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino}benzoate

(Z)-Avenanthramide E is found in cereals and cereal products. (Z)-Avenanthramide E is isolated from oat. Isolated from the oat Avena sativa. Avenanthramide E is found in oat and cereals and cereal products.

2-Methylthioadenosine

2-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

C11H15N5O4S (313.0845)

4-(4-Guanidinobenzoyloxy)phenylacetate

2-(4-{4-[(diaminomethylidene)amino]benzoyloxy}phenyl)acetic acid

C16H15N3O4 (313.1063)

4-Hydroxy Duloxetine

4-[3-(methylamino)-1-(thiophen-2-yl)propoxy]naphthalen-1-ol

C18H19NO2S (313.1136)

L-Chlorozotocin

1-(2-chloroethyl)-1-nitroso-3-(3,4,5,6-tetrahydroxy-1-oxohexan-2-yl)urea

C9H16ClN3O7 (313.0677)

D009676 - Noxae > D002273 - Carcinogens D000970 - Antineoplastic Agents

BEMESETRON

8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3,5-dichlorobenzoate

C15H17Cl2NO2 (313.0636)

Benorilate

N-{4-[2-(acetyloxy)benzoyloxy]phenyl}ethanimidate

N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BA - Salicylic acid and derivatives D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D018501 - Antirheumatic Agents

Flubendazole

N-[6-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]methoxycarboximidic acid

P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02C - Antinematodal agents > P02CA - Benzimidazole derivatives D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites[1][2].

Mitonafide

3-[2-(dimethylamino)ethyl]-11-nitro-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaene-2,4-dione

C16H15N3O4 (313.1063)

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D000970 - Antineoplastic Agents

N-(4-Methylphenyl)diphenimide

9-(4-methylphenyl)-9-azatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2,4,6,11,13-hexaene-8,10-dione

Pipethiadene

4-{6,8-dithiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene}-1-methylpiperidine

C18H19NS2 (313.0959)

Rentiapril

2-(2-Hydroxyphenyl)-3-(3-sulphanylpropanoyl)-1,3-thiazolidine-4-carboxylic acid

Salicylamide glucuronide

3,4,5-Trihydroxy-6-[2-(C-hydroxycarbonimidoyl)phenoxy]oxane-2-carboxylate

C13H15NO8 (313.0798)

N-(5-Chlorosalicyloyl)-8-aminocaprylic acid

8-{[(5-chloro-2-hydroxyphenyl)(hydroxy)methylidene]amino}octanoate

N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CD - Benzodiazepine derivatives D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent CONFIDENCE standard compound; EAWAG_UCHEM_ID 3681 CONFIDENCE standard compound; INTERNAL_ID 1595

C14H19NO7_(2R)-2-(beta-D-Glucopyranosyloxy)-2-phenylacetamide

NCGC00385280-01_C14H19NO7_(2R)-2-(beta-D-Glucopyranosyloxy)-2-phenylacetamide

3,5-Cyclic dAMP

3,5-Cyclic 2-Deoxyadenosine monophosphate

2-Deoxyadenosine cyclic 3,5-(hydrogen phosphate)

MMV688776

C17H16N3OCl (313.0982)

(6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride

C9H17Cl2N5O3 (313.0708)

Benorylate

amoxapine

N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AA - Non-selective monoamine reuptake inhibitors D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent > C94727 - Tricyclic Antidepressant D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D049990 - Membrane Transport Modulators CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7940; ORIGINAL_PRECURSOR_SCAN_NO 7938 CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7961; ORIGINAL_PRECURSOR_SCAN_NO 7960 CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7991; ORIGINAL_PRECURSOR_SCAN_NO 7989 CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7990; ORIGINAL_PRECURSOR_SCAN_NO 7988 CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7970; ORIGINAL_PRECURSOR_SCAN_NO 7967 CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7997; ORIGINAL_PRECURSOR_SCAN_NO 7994

Salinosporamide A

3-[4-(4-morpholinyl)thieno[3,2-d]pyrimidin-2-yl-phenol

C16H15N3O2S (313.0885)

Tyramine glucuronide

4-(2-Aminoethyl)phenyl-beta-delta-glucopyranosiduronic acid

PMAC

10-methyl-9-(phenoxycarbonyl) Acridinium fluorosulfonate

albendazole (II)

C12H15N3O5S (313.0732)

Avenanthramide 1f

2-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamido]benzoic acid

5'-Deoxy-5'-(methylsulfinyl)adenosine, 9CI

2-(6-amino-9H-purin-9-yl)-5-(methanesulfinylmethyl)oxolane-3,4-diol

C11H15N5O4S (313.0845)

Avenanthramide E

2-[(2Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamido]benzoic acid

D-Glucose,2-deoxy-2-[[(phenylmethoxy)carbonyl]amino]-

9-Benzyl-9H-carbazole-3,6-dicarbaldehyde

(1R,2S)-Methyl 1-amino-2-vinylcyclopropanecarboxylate 4-methylbenzenesulfonate

C14H19NO5S (313.0984)

6-(BROMOMETHYL)-4-(3-METHOXYPROPYL)-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE

tert-Butyl 7,8-dihydro-2-(methylsulfonyl)pyrido[4,3-d]pyrimidine-6(5H)-carboxylate

C13H19N3O4S (313.1096)

Sulfadoxine D3

C12H11D3N4O4S (313.0924)

2-(1-Oxy-pyridin-2-yl)-1,1,3,3-tetramethylisothiouronium tetrafluoroborate

C10H16BF4N3OS (313.1043)

5-(4-BROMO-PHENYL)-2-PHENYL-2H-PYRAZOL-3-YLAMINE

C15H12BrN3 (313.0215)

HDAOS

C11H16NNaO6S (313.0596)

4-Nitrobenzo-15-crown-5

1-Diphenylmethylindoline-2,3-dione

1,4-Dihydro-1-(6-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic acid

C16H15N3O4 (313.1063)

Boc-D-N-Me-Phe-OH

9,10-Anthracenedione,1-amino-4-hydroxy-2-(2-methoxyethoxy)-

Boc-(R)-3-AMino-4-(3-chloro-phenyl)-butyric acid

5-(3-bromophenyl)-2-phenylpyrazol-3-amine

C15H12BrN3 (313.0215)

2-BROMO-4-METHOXY-6-NITROBENZENOL

Fmoc-aoac-oh

[2-(3-BROMO-PHENYL)-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

3,5-DI(BENZO(D)OXAZOL-2-YL)PYRIDINE

C19H11N3O2 (313.0851)

4-BROMO-N,N-DIISOPROPYL-3-METHOXYBENZAMIDE

C14H20BrNO2 (313.0677)

BenzeneMethanol, α-(aminomethyl)-α-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)-

7-piperazin-1-yl-2-(3-pyridyl)thiazolo[5,4-d]pyrimidin-5-amine

C14H15N7S (313.111)

(2S, 3S)-3-(Boc-amino)-2-Methyl-3-(4-chlorophenyl)propionic acid

ethyl 5-oxo-3-[3-(trifluoromethyl)phenyl]-2H-1,2,4-triazine-6-carboxylate

C13H10F3N3O3 (313.0674)

Naphthol AS-BO

MDL 72222

C15H17Cl2NO2 (313.0636)

Bemesetron (MDL 72222) is a selective 5-HT3 receptor antagonist with an IC50 of 0.33 nM[1]. Neuroprotective effect[2].

piclonidine

C14H17Cl2N3O (313.0749)

tert-Butyl 6-bromo-2H-benzo[b][1,4]oxazine-4(3H)-carboxylate

5-[(4-METHOXYPHENOXY)METHYL]-4-PHENYL-4H-1,2,4-TRIAZOLE-3-THIOL

C16H15N3O2S (313.0885)

2-(7-amino-4-methyl-2-oxo-6-sulfochromen-3-yl)acetic acid

C12H11NO7S (313.0256)

N-Acetyl-3,5-dinitrotyrosine

C11H11N3O8 (313.0546)

3-Hydroxy-N-2-naphthyl-2-naphthamide

3-(2,6-dichloro-phenyl)-5-isopropyl-isoxazole-4-carboxylic acid methyl ester

C14H13Cl2NO3 (313.0272)

YM 976

4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one

8-chloro-1-methyl-6-(2,3,4,5,6-pentadeuteriophenyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

C17H8ClD5N4 (313.1143)

Carboxypeptidase G2 (CPG2) Inhibitor

C13H15NO6S (313.062)

2-(Fluoroacetyl)-3-(2-methylphenyl)-6-nitroquinazolin-4(3H)-one

5-CHLORO-2-(3-HYDROXYMETHYL-4H-1,2,4-TRIAZOL-4-YL)BENZOPHENONE

C16H12ClN3O2 (313.0618)

Amezinium metilsulfate

Amezinium methylsulfate

C12H15N3O5S (313.0732)

C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. Target: alpha and beta-1 receptors Amezinium metilsulfate is a sympathomimetic drug used for the treatment of low blood pressure. Cardiovascular effects of the new sympathomimetic Amezinium metilsulphate are investigated in 25 patients compared with a control group (n = 25). During spinal/epidural anaesthesia 5 mg amezinium is given i.v. if blood pressure dropped greater than 20 mmHg. from starting-point. A significant recovery of blood pressure (epidural anaesthesia: syst 21\%, diast 9\%; spinal anaesthesia: syst 13\%, diast 6.6\%) and a decrease in heart rate (6.8\% resp. 4,5\%) are thought due to peripheral vasoconstriction. Amezinium proves a stimulating drug for alpha- and beta 1-receptors by stabilising the systemic blood pressure in spinal/epidural anaesthesia.

2-N-BOC-2-AMINOMETHYL-3-(4-CHLORO-PHENYL)-PROPIONIC ACID

benzyl 4-(methanesulfonyloxy)piperidine-1-carboxylate

C14H19NO5S (313.0984)

ethyl 5-bromo-2-morpholin-4-ylbenzoate

ethyl 3-bromo-4-morpholin-4-ylbenzoate

N-Hexylpyridinium Trifluoromethanesulfonate

C12H18F3NO3S (313.0959)

3-[1-[(3,5-difluorophenyl)methyl]indol-3-yl]prop-2-enoic acid

C18H13F2NO2 (313.0914)

METHYL 4-(PROPYLSULFONYL)-3-(1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLATE

(1-HYDROXYOCTANE-1,1-DIYL)DIPHOSPHONIC ACID

C8H20NaO7P2+ (313.0582)

methyl 4-(isopropylsulfonyl)-3-(1H-pyrrol-1-yl)thiophene-2-carboxylate

3-(4-fluorophenyl)-5-p-tolyl-4,5-dihydro-1h-pyrazole-1-carbothioamide

C17H16FN3S (313.1049)

N-Boc-4-(2-Bromo-acetyl)-aniline

Boc-(R)-3-amino-4-(2-chlorophenyl)-butyric acid

dnp-dl-glutamic acid

C11H11N3O8 (313.0546)

Etaconazole

C13H13Cl2N3O2 (313.0385)

N-Boc-7-Bromo-3,4-dihydro-2H-benzo[1,4]oxazine

2-Methyl-5-{3-[4-(methylsulfonyl)phenyl]-2-furyl}pyridine

2-chloro-N-(2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide

C14H18BClFNO3 (313.1052)

2,4-dimethoxy-4-nitrochalcone

2,4-dimethoxy-2-nitrochalcone

2,6-BIS(BENZO[D]OXAZOL-2-YL)PYRIDINE

C19H11N3O2 (313.0851)

Methyl 4,5-Di(1-imidazolyl)-2-nitrobenzoate

C14H11N5O4 (313.0811)

8-chloro-1-methyl-1,2,3,4-tetrahydropyrimido[1,6-a]pyrimidin-6-one trifluoroacetate

C10H11ClF3N3O3 (313.0441)

Ethyl 6,7-difluoro-2-ethylmercapto-4-hydroxyquinoline-3-carboxylate

C14H13F2NO3S (313.0584)

1-[3-(3-Bromophenoxy)propyl]-4-piperidinol

C14H20BrNO2 (313.0677)

6-Fluoro-3-indolyl-b-D-galactopyranoside

C14H16FNO6 (313.0962)

7-Amino-3-(1,2,3-triazol-4-ylthio)methyl cephalosporanic acid

C10H11N5O3S2 (313.0303)

5-（4-Chlorophenyl)-3-p-tolyl-4,5-dihydro-1H-pyrazole-1-carboxamide

2-(1-OXOPROPYL)-1-(PHENYLSULFONYL)-1H-INDOLE

2,6-tns

4-[4-(4-nitrophenoxy)phenyl]thiazol-2-ylamine

C15H11N3O3S (313.0521)

(6-BROMO-HEXYL)-CARBAMIC ACID BENZYL ESTER

C14H20BrNO2 (313.0677)

beta-d-glucopyranosylphenyl isothiocyanate

C13H15NO6S (313.062)

8-Azabicyclo(3.2.1]octane, 3-(3,4-dichlorophenyl)-2-(methoxymethyl)-8-methyl-, (1R,2R,3S,5S)-

C16H21Cl2NO (313.1)

2,3-diphenyl-1H-indole-7-carboxylic acid

3-Tropanyl-3,5-dichlorobenzoate

C15H17Cl2NO2 (313.0636)

D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists

4-Thiazolidinecarboxylic acid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-