amoxapine (BioDeep_00000408926)

Volatile Flavor Compounds

代谢物信息卡片

amoxapine

化学式: C17H16ClN3O (313.09818359999997)
中文名称: 阿莫沙平, 阿莫西平
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
InChI: InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2

描述信息

N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants > N06AA - Non-selective monoamine reuptake inhibitors
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017367 - Selective Serotonin Reuptake Inhibitors
C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent > C94727 - Tricyclic Antidepressant
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents
D049990 - Membrane Transport Modulators
CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7940; ORIGINAL_PRECURSOR_SCAN_NO 7938
CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7961; ORIGINAL_PRECURSOR_SCAN_NO 7960
CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7991; ORIGINAL_PRECURSOR_SCAN_NO 7989
CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7990; ORIGINAL_PRECURSOR_SCAN_NO 7988
CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7970; ORIGINAL_PRECURSOR_SCAN_NO 7967
CONFIDENCE standard compound; INTERNAL_ID 902; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7997; ORIGINAL_PRECURSOR_SCAN_NO 7994

同义名列表

2 个代谢物同义名

amoxapine; Amoxapine

数据库引用编号

19 个数据库交叉引用编号

ChEBI: CHEBI:2675
KEGGdrug: D00228
PubChem: 2170
Metlin: METLIN982
DrugBank: DB00543
ChEMBL: CHEMBL1113
MeSH: Amoxapine
CAS: 14028-44-5
MoNA: LU090206
MoNA: LU090205
MoNA: LU090204
MoNA: LU090203
MoNA: LU090202
MoNA: LU090201
MoNA: WA002133
MoNA: WA002132
MoNA: WA002131
MoNA: WA002130
MoNA: WA002129

分类词条

有机杂环化合物

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Sandeep Jat, Manini Bhatt, Sanjana Roychowdhury, Vaibhav A Dixit, Sachin Dattram Pawar, Hitesh Kulhari, Amit Alexander, Pramod Kumar. Preparation and characterization of amoxapine- and naringin-loaded solid lipid nanoparticles: drug-release and molecular-docking studies. Nanomedicine (London, England). 2023 Feb; ?(?):. doi: 10.2217/nnm-2022-0167. [PMID: 36786368]
Masaru Matsuoka, Toru Imai, Sou Iwabuchi, Kosaku Kinoshita. Successful Treatment of Amoxapine-Induced Intractable Seizures With Intravenous Lipid Emulsion. The Journal of emergency medicine. 2023 Jan; 64(1):62-66. doi: 10.1016/j.jemermed.2022.10.016. [PMID: 36450616]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
Ayça Karasakal, Sevgi Tatar Ulu. Development and validation of a sensitive spectrofluorimetric method for the determination of amoxapine in human plasma and urine. Luminescence : the journal of biological and chemical luminescence. 2014 May; 29(3):284-7. doi: 10.1002/bio.2541. [PMID: 23780763]
Cho-Ming Loi, Dennis A Smith, Deepak Dalvie. Which metabolites circulate?. Drug metabolism and disposition: the biological fate of chemicals. 2013 May; 41(5):933-51. doi: 10.1124/dmd.112.050278. [PMID: 23454828]
Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
Yin Cheong Wong, Siu Kwan Wo, Zhong Zuo. Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS. Journal of pharmaceutical and biomedical analysis. 2012 Jan; 58(?):83-93. doi: 10.1016/j.jpba.2011.09.020. [PMID: 21993198]
Gerile, Chiharu Sogawa, Kazumi Ohyama, Takashi Masuko, Tadashi Kusama, Katsuya Morita, Norio Sogawa, Shigeo Kitayama. Inhibitory action of antidepressants on mouse Betaine/GABA transporter (BGT1) heterologously expressed in cell cultures. International journal of molecular sciences. 2012; 13(3):2578-2589. doi: 10.3390/ijms13032578. [PMID: 22489112]
Jennifer S D Zimmer, Shane R Needham, Chad D Christianson, Crystal M Piekarski, Chrystal N Sheaff, Keith Huie, Andrea R Reed, Lori Takahashi. Validation of HPLC-MS/MS methods for analysis of loxapine, amoxapine, 7-OH-loxapine, 8-OH-loxapine and loxapine N-oxide in human plasma. Bioanalysis. 2010 Dec; 2(12):1989-2000. doi: 10.4155/bio.10.156. [PMID: 21110742]
Manju Gupta, Archana Jain, Krishna K Verma. Determination of amoxapine and nortriptyline in blood plasma and serum by salt-assisted liquid-liquid microextraction and high-performance liquid chromatography. Journal of separation science. 2010 Dec; 33(23-24):3774-80. doi: 10.1002/jssc.201000434. [PMID: 21082678]
Joseph H Kennedy, Justin M Wiseman. Evaluation and performance of desorption electrospray ionization using a triple quadrupole mass spectrometer for quantitation of pharmaceuticals in plasma. Rapid communications in mass spectrometry : RCM. 2010 Feb; 24(3):309-14. doi: 10.1002/rcm.4390. [PMID: 20049888]
Yusuke Nakazawa, Takashi Okura, Keita Shimomura, Tetsuya Terasaki, Yoshiharu Deguchi. Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect. Journal of pharmaceutical sciences. 2010 Jan; 99(1):467-74. doi: 10.1002/jps.21807. [PMID: 19499573]
Hong Wan, Madeleine Ahman, Anders G Holmén. Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry. 2009 Mar; 52(6):1693-700. doi: 10.1021/jm801441s. [PMID: 19256501]
Xin-Jun Zhang, Li-Hao Ge, Jian Liu, Xiong-Li Yang. Functional expression of the glycine transporter 1 on bullfrog retinal cones. Neuroreport. 2008 Nov; 19(17):1667-71. doi: 10.1097/wnr.0b013e3283155186. [PMID: 18841092]
Xiao-Pen Lee, Chika Hasegawa, Takeshi Kumazawa, Natsuko Shinmen, Yukiko Shoji, Hiroshi Seno, Keizo Sato. Determination of tricyclic antidepressants in human plasma using pipette tip solid-phase extraction and gas chromatography-mass spectrometry. Journal of separation science. 2008 Jul; 31(12):2265-71. doi: 10.1002/jssc.200700627. [PMID: 18546392]
Zheng Jiang, Baoqin Li, Frantisek Jursky, Wen Shen. Differential distribution of glycine transporters in Müller cells and neurons in amphibian retinas. Visual neuroscience. 2007 Mar; 24(2):157-68. doi: 10.1017/s0952523807070186. [PMID: 17640406]
Tatsuo Shinozuka, Masaru Terada, Einosuke Tanaka. Solid-phase extraction and analysis of 20 antidepressant drugs in human plasma by LC/MS with SSI method. Forensic science international. 2006 Oct; 162(1-3):108-12. doi: 10.1016/j.forsciint.2006.03.038. [PMID: 16859851]
Rocío Salceda. Pharmacological properties of glycine uptake in the developing rat retina. Neurochemistry international. 2006 Sep; 49(4):342-6. doi: 10.1016/j.neuint.2006.02.006. [PMID: 16621161]
Makiko Goto, Reiji Yoshimura, Shingo Kakihara, Koji Shinkai, Yasuhisa Yamada, Kyoko Kaji, Nobuhisa Ueda, Jun Nakamura. Risperidone in the treatment of psychotic depression. Progress in neuro-psychopharmacology & biological psychiatry. 2006 Jun; 30(4):701-7. doi: 10.1016/j.pnpbp.2006.01.016. [PMID: 16580110]
Yasuhiko Higashi, Miyuki Kitahara, Youichi Fujii. Simultaneous analysis of haloperidol, its three metabolites and two other butyrophenone-type neuroleptics by high performance liquid chromatography with dual ultraviolet detection. Biomedical chromatography : BMC. 2006 Feb; 20(2):166-72. doi: 10.1002/bmc.547. [PMID: 16034821]
F L Sauvage, J M Gaulier, G Lachâtre, P Marquet. A fully automated turbulent-flow liquid chromatography-tandem mass spectrometry technique for monitoring antidepressants in human serum. Therapeutic drug monitoring. 2006 Feb; 28(1):123-30. doi: 10.1097/01.ftd.0000194026.04483.c3. [PMID: 16418706]
Hao Huang, Latifa Barakat, Doris Wang, Angélique Bordey. Bergmann glial GlyT1 mediates glycine uptake and release in mouse cerebellar slices. The Journal of physiology. 2004 Nov; 560(Pt 3):721-36. doi: 10.1113/jphysiol.2004.067801. [PMID: 15331688]
Tom Schilling, Claudia Eder. A novel physiological mechanism of glycine-induced immunomodulation: Na+-coupled amino acid transporter currents in cultured brain macrophages. The Journal of physiology. 2004 Aug; 559(Pt 1):35-40. doi: 10.1113/jphysiol.2004.070763. [PMID: 15243140]
Tetsuya Suhara, Yota Fujimura. [Biological pathophysiology of mood disorders special reference to the neurotransmitter receptors]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. 2004; 106(8):1032-6. doi: NULL. [PMID: 15655900]
L Raiteri, M Raiteri, G Bonanno. Glycine is taken up through GLYT1 and GLYT2 transporters into mouse spinal cord axon terminals and causes vesicular and carrier-mediated release of its proposed co-transmitter GABA. Journal of neurochemistry. 2001 Mar; 76(6):1823-32. doi: 10.1046/j.1471-4159.2001.00159.x. [PMID: 11259500]
S Gupta, A A Racaniello. Neuroleptic malignant syndrome associated with amoxapine and lithium in an older adult. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. 2000 Jun; 12(2):107-9. doi: 10.1023/a:1009028315246. [PMID: 10907803]
E Núñez, B López-Corcuera, J Vázquez, C Giménez, C Aragón. Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters. British journal of pharmacology. 2000 Jan; 129(1):200-6. doi: 10.1038/sj.bjp.0703049. [PMID: 10694221]
K K Midha, J W Hubbard, G McKay, M J Rawson, D Hsia. The role of metabolites in a bioequivalence study II: amoxapine, 7-hydroxyamoxapine, and 8-hydroxyamoxapine. International journal of clinical pharmacology and therapeutics. 1999 Sep; 37(9):428-38. doi: NULL. [PMID: 10507241]
C Quiñones-Torrelo, S Sagrado, R M Villanueva-Camañas, M J Medina-Hernández. Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography. Journal of medicinal chemistry. 1999 Aug; 42(16):3154-62. doi: 10.1021/jm9910369. [PMID: 10447960]
F Pisani, E Spina, G Oteri. Antidepressant drugs and seizure susceptibility: from in vitro data to clinical practice. Epilepsia. 1999; 40 Suppl 10(?):S48-56. doi: 10.1111/j.1528-1157.1999.tb00885.x. [PMID: 10609604]
B Hüe, B Palomba, M Giacardy-Paty, T Bottaï, R Alric, P Petit. Concurrent high-performance liquid chromatographic measurement of loxapine and amoxapine and of their hydroxylated metabolites in plasma. Therapeutic drug monitoring. 1998 Jun; 20(3):335-9. doi: 10.1097/00007691-199806000-00016. [PMID: 9631933]
A H Glassman, X A Preud'homme. Review of the cardiovascular effects of heterocyclic antidepressants. The Journal of clinical psychiatry. 1993 Feb; 54 Suppl(?):16-22. doi: NULL. [PMID: 8444830]
P Saviuc, V Danel, D Waldner, A Claustre. [Acute amoxapine poisoning with rhabdomyolysis and acute renal insufficiency]. Journal de toxicologie clinique et experimentale. 1992 Dec; 12(8):487-9. doi: NULL. [PMID: 1308897]
A Kobayashi, K Fujita, K Nakazawa. In rat brain amoxapine enhances dopamine metabolism: pharmacokinetic variations of the effect. European journal of pharmacology. 1992 Apr; 215(1):43-9. doi: 10.1016/0014-2999(92)90606-5. [PMID: 1516649]
S W Cheung, S W Tang, G Remington. Simultaneous quantitation of loxapine, amoxapine and their 7- and 8-hydroxy metabolites in plasma by high-performance liquid chromatography. Journal of chromatography. 1991 Mar; 564(1):213-21. doi: 10.1016/0378-4347(91)80083-o. [PMID: 1860915]
F Skinazi, P Davous, G Bleichner. [Acute kidney failure after voluntary poisoning with amoxapine]. Presse medicale (Paris, France : 1983). 1991 Jan; 20(3):130. doi: NULL. [PMID: 1825727]
K Matsumoto, S Kanba, H Kubo, G Yagi, H Iri, H Yuki. Automated determination of drugs in serum by column-switching high-performance liquid chromatography. IV. Separation of tricyclic and tetracyclic antidepressants and their metabolites. Clinical chemistry. 1989 Mar; 35(3):453-6. doi: 10.1093/clinchem/35.3.453. [PMID: 2920412]
K Selinger, G Lebel, H M Hill, J A Anslow. A high-performance liquid chromatographic method for the analysis of amoxapine in human plasma. Journal of pharmaceutical and biomedical analysis. 1989; 7(8):1001-7. doi: 10.1016/0731-7085(89)80026-3. [PMID: 2490101]
K Koizumi, T Aono, O Tanizawa. The acute effects of antidepressants, maprotiline and amoxapine on serum prolactin and gonadotropin levels in normal women. Asia-Oceania journal of obstetrics and gynaecology. 1986 Dec; 12(4):517-21. doi: 10.1111/j.1447-0756.1986.tb00228.x. [PMID: 3103591]
J Jones, D Heiselman, J Dougherty, A Eddy. Cathartic-induced magnesium toxicity during overdose management. Annals of emergency medicine. 1986 Oct; 15(10):1214-8. doi: 10.1016/s0196-0644(86)80870-8. [PMID: 3752654]
R K Mahapatra, S K Paul, D Mahapatra, S Winter. Cardiovascular effects of polycyclic antidepressants. Angiology. 1986 Oct; 37(10):709-17. doi: 10.1177/000331978603701003. [PMID: 3767060]
P E Hayes, C A Kristoff. Adverse reactions to five new antidepressants. Clinical pharmacy. 1986 Jun; 5(6):471-80. doi: NULL. [PMID: 3087684]
J Arditti, P Jean, J M David, J H Bourdon, M Hayek-Lanthois, J Jouglard. [Acute intoxication by amoxapine. Plasma analysis in 2 cases]. Journal de toxicologie clinique et experimentale. 1986 Mar; 6(2):107-14. doi: NULL. [PMID: 3783483]
A Kobayashi, S Sugita, K Nakazawa. Determination of amoxapine and its metabolites in human serum by high-performance liquid chromatography. Neuropharmacology. 1985 Dec; 24(12):1253-6. doi: 10.1016/0028-3908(85)90162-5. [PMID: 4094661]
G R Gaffney, L E Tune. Serum neuroleptic levels and extrapyramidal side effects in patients treated with amoxapine. The Journal of clinical psychiatry. 1985 Oct; 46(10):428-9. doi: NULL. [PMID: 2864332]
T J Frendin, C P Swainson. Acute renal failure secondary to non-traumatic rhabdomyolysis following amoxapine overdose. The New Zealand medical journal. 1985 Aug; 98(785):690-1. doi: NULL. [PMID: 3863031]
C C Chu, C V Wadle, S L Ruedrich. Amoxapine-associated acute renal failure. Southern medical journal. 1985 Jun; 78(6):761. doi: 10.1097/00007611-198506000-00042. [PMID: 4002015]
B Calvo, M J García, J L Pedraz, E L Mariño, A Domínguez-Gil. Pharmacokinetics of amoxapine and its active metabolites. International journal of clinical pharmacology, therapy, and toxicology. 1985 Apr; 23(4):180-5. doi: NULL. [PMID: 3997304]
R F Suckow, T B Cooper. Determination of amoxapine and metabolites in plasma by liquid chromatography with electrochemical detection. Journal of chromatography. 1985 Feb; 338(1):225-9. doi: 10.1016/0378-4347(85)80090-6. [PMID: 4019648]
C C Chu, C V Wadle, S L Ruedrich. Acute renal failure associated with amoxapine overdose. The Nebraska medical journal. 1984 Oct; 69(10):338-9. doi: NULL. [PMID: 6493391]
C L Winek, W W Wahba, L Rozin. Amoxapine fatalities: three case studies. Forensic science international. 1984 Sep; 26(1):33-8. doi: 10.1016/0379-0738(84)90209-3. [PMID: 6510852]
S M Johnson, G Nygard, S K Khalil. Isocratic liquid chromatographic method for the determination of amoxapine and its metabolites. Journal of pharmaceutical sciences. 1984 May; 73(5):696-9. doi: 10.1002/jps.2600730529. [PMID: 6737248]
J J Tasset, A J Pesce. Amoxapine in human overdose. Journal of analytical toxicology. 1984 May; 8(3):124-8. doi: 10.1093/jat/8.3.124. [PMID: 6738000]
A D Rogol, R Schoumacher, D A Spyker. Generalized convulsions as the presenting sign of amoxapine intoxication. Clinical pediatrics. 1984 Apr; 23(4):235-7. doi: 10.1177/000992288402300411. [PMID: 6697633]
P E Hayes, W C Nash, P Ettigi, W R Garnett, C S Dommisse. Effect of amoxapine on serum prolactin concentrations in normal men. Clinical pharmacy. 1984 Mar; 3(2):189-91. doi: NULL. [PMID: 6723227]
A J Gelenberg, J D Wojcik, R B Lydiard, M G McCormick, W E Falk, R H Hicks, F C Curren, B M Cohen. Double-blind comparison of amoxapine and imipramine in the treatment of depressed patients. The Journal of clinical psychiatry. 1984 Feb; 45(2):54-56, 57. doi: NULL. [PMID: 6363397]
N Yufu, M Itoh, A Notomi, H Nakao. Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography. Folia psychiatrica et neurologica japonica. 1984; 38(1):57-64. doi: 10.1111/j.1440-1819.1984.tb00355.x. [PMID: 6537393]
R F Anton, J D Sexauer, C L Randall. Amoxapine elevates serum prolactin in depressed men. Journal of affective disorders. 1983 Nov; 5(4):305-10. doi: 10.1016/0165-0327(83)90020-4. [PMID: 6229562]
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T Sunderland, P J Orsulak, B M Cohen. Amoxapine and neuroleptic side effects: a case report. The American journal of psychiatry. 1983 Sep; 140(9):1233-5. doi: 10.1176/ajp.140.9.1233. [PMID: 6137151]
E A Burch, T J Goldschmidt. Loxapine in the treatment of psychotic-depressive disorders: Measurement of antidepressant metabolites. Southern medical journal. 1983 Aug; 76(8):991-5. doi: 10.1097/00007611-198308000-00012. [PMID: 6879296]
A E Jennings, A S Levey, J T Harrington. Amoxapine-associated acute renal failure. Archives of internal medicine. 1983 Aug; 143(8):1525-7. doi: NULL. [PMID: 6870433]
S H Wong, S W Waugh. Determination of the antidepressants maprotiline and amoxapine, and their metabolites, in plasma by liquid chromatography. Clinical chemistry. 1983 Feb; 29(2):314-8. doi: . [PMID: 6821936]
F A Beierle, R W Hubbard. Liquid chromatographic separation of antidepressant drugs: II. Amoxapine and maprotiline. Therapeutic drug monitoring. 1983; 5(3):293-301. doi: 10.1097/00007691-198309000-00009. [PMID: 6636257]
A J Pumariega, B Muller, N R Rivers-Bulkeley. Acute renal failure secondary to amoxapine overdose. JAMA. 1982 Dec; 248(23):3141-2. doi: NULL. [PMID: 7143692]
R L Taylor, C R Crooks, Y H Caplan. The determination of amoxapine in human fatal overdoses. Journal of analytical toxicology. 1982 Nov; 6(6):309-11. doi: 10.1093/jat/6.6.309. [PMID: 7162142]
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D F Kimball, A A Lampert. Analysis of amoxapine and its metabolites in human plasma by high pressure liquid chromatography. South Dakota journal of medicine. 1982 Oct; 35(10):31-3. doi: NULL. [PMID: 6959285]
K Abero, W D Shelp, A Kosseff, S Thomas. Amoxapine-associated rhabdomyolysis and acute renal failure: case report. The Journal of clinical psychiatry. 1982 Oct; 43(10):426-7. doi: NULL. [PMID: 7118837]
J L Kinney, R L Evans. Evaluation of amoxapine. Clinical pharmacy. 1982 Sep; 1(5):417-24. doi: . [PMID: 6764165]
M A Click, S Zisook. Amoxapine and amitriptyline: serum levels and clinical response in patients with primary unipolar depression. The Journal of clinical psychiatry. 1982 Sep; 43(9):369-71. doi: NULL. [PMID: 6749828]
J E Dugas, S S Weber. Amoxapine (Asendin, Lederle Laboratories). Drug intelligence & clinical pharmacy. 1982 Mar; 16(3):199-204. doi: 10.1177/106002808201600302. [PMID: 7037342]
A G Robertson, R Berry, H Y Meltzer. Prolactin stimulating effects of amoxapine and loxapine in psychiatric patients. Psychopharmacology. 1982; 78(3):287-92. doi: 10.1007/bf00428168. [PMID: 6818584]
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