Exact Mass: 227.05131579999997
Exact Mass Matches: 227.05131579999997
Found 500 metabolites which its exact mass value is equals to given mass value 227.05131579999997,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Deoxycytidine
Deoxycytidine, also known as dC, belongs to the class of organic compounds known as pyrimidine 2-deoxyribonucleosides. Pyrimidine 2-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. Deoxycytidine is also classified as a deoxyribonucleoside, a component of deoxyribonucleic acid (DNA). Deoxycytidine is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the 2 position. Deoxycytidine exists in all living species, ranging from bacteria to plants to humans. Degradation of DNA through apoptosis or cell death produces deoxycytidine. Within humans, deoxycytidine participates in a number of enzymatic reactions. In particular, deoxycytidine can be biosynthesized from dCMP through the action of the enzyme cytosolic purine 5-nucleotidase. In addition, deoxycytidine can be converted into dCMP; which is mediated by the enzyme uridine-cytidine kinase-like 1. Deoxycytidine can be phosphorylated at the C-5 position by the enzyme deoxycytidine kinase to produce deoxycytidine monophosphate (dCMP), and to a lesser extent, deoxycytidine diphosphate (dCDP), and deoxycytidine triphosphate (dCTP). Deoxycytidine can also be phosphorylated by thymidine kinase 2 (TK2). Deoxycytidine can potentially be used for the treatment of the metabolic disorder known as thymidine kinase 2 deficiency (TK2 deficiency). TK2 deficiency has three disease subtypes: i) infantile-onset myopathy with rapid progression to early death ii) childhood-onset myopathy, which resembles spinal muscular atrophy (SMA) type III, begins between ages 1 and 12 years with progression to loss of ambulation within few years and iii) late-onset myopathy starting at age 12 year or later with moderate to severe myopathy manifesting as either isolated chronic progressive external ophthalmoplegia (CPEO) or a generalized myopathy with CPEO plus facial and limb weakness, gradual progression, and, in some cases, respiratory failure and loss of ability to walk in adulthood (PMID: 28318037). In mouse models of TK2, dC was shown to delay disease onset, prolong life span and restore mtDNA copy number as well as respiratory chain enzyme activities (PMID: 28318037). One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phosphate group. When N1 is linked to the C1 of deoxyribose, deoxynucleosides and nucleotides are formed from cytosine and deoxyribose; deoxycytidine monophosphate (dCMP), deoxycytidine diphosphate (dCDP), deoxycytidine triphosphate (dCTP). CTP is the source of the cytidine in RNA (ribonucleic acid) and deoxycytidine triphosphate (dCTP) is the source of the deoxycytidine in DNA (deoxyribonucleic acid). [HMDB]. Deoxycytidine is found in many foods, some of which are japanese pumpkin, turmeric, prairie turnip, and kai-lan. C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite Acquisition and generation of the data is financially supported in part by CREST/JST. C26170 - Protective Agent > C2459 - Chemoprotective Agent COVID info from COVID-19 Disease Map KEIO_ID D055; [MS2] KO008940 Corona-virus KEIO_ID D055 Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
Flindersine
C14H13NO2 (227.09462380000002)
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.139 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.140
2,4,6-Trinitrotoluene
Trinitrotoluene, also known as tnt or S-trinitrotoluol, is a member of the class of compounds known as nitrobenzenes. Nitrobenzenes are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group. Trinitrotoluene is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Trinitrotoluene can be found in a number of food items such as parsnip, broccoli, highbush blueberry, and sunburst squash (pattypan squash), which makes trinitrotoluene a potential biomarker for the consumption of these food products. Trinitrotoluene is formally rated as an unfounded non-carcinogenic (IARC 3) potentially toxic compound. Trinitrotoluene (; TNT), or more specifically 2,4,6-trinitrotoluene, is a chemical compound with the formula C6H2(NO2)3CH3. This yellow solid is sometimes used as a reagent in chemical synthesis, but it is best known as an explosive material with convenient handling properties. The explosive yield of TNT is considered to be the standard measure of bombs and other explosives. In chemistry, TNT is used to generate charge transfer salts . In some cases, gastric lavage, activated charcoal, and emetics have been suggested as useful in reducing absorption of the general class of nitro compounds to which 2,4,6-trinitrotoluene belongs (L132) (T3DB). CONFIDENCE standard compound; INTERNAL_ID 42 D053834 - Explosive Agents
L-Glutamic acid 5-phosphate
L-Glutamic acid 5-phosphate is an intermediate in the urea cycle and the metabolism of amino groups. It is a substrate of aldehyde dehydrogenase 18 family, member A1 [EC:2.7.2.11 1.2.1.41] (KEGG)In citrulline biosynthesis, it is a substrate of the enzyme glutamate-5-semialdehyde dehydrogenase [EC 1.2.1.41] and in proline synthesis it is a substrate of the enzyme Glutamate 5-kinase [EC 2.7.2.11] (BioCyc). L-Glutamic acid 5-phosphate is an intermediate in the urea cycle and metabolism of amino groups, a substrate of aldehyde dehydrogenase 18 family, member A1 [EC:2.7.2.11 1.2.1.41] (KEGG)
5-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate
5-(2-Carboxyethyl)-4,6-Dihydroxypicolinate is involved in the tryptophan metabolism system. Through a number of reactions, L-Kynurenine is converted to 5-(2-Carboxyethyl)-4,6-Dihydroxypicolinate. The last reaction involves 5-(2-formylethyl)-4,6-Dihydroxypicolinate being converted into 5-(2-Carboxyethyl)-4,6-Dihydroxypicolinate by [E1.2.1.-]. [HMDB] 5-(2-Carboxyethyl)-4,6-Dihydroxypicolinate is involved in the tryptophan metabolism system. Through a number of reactions, L-Kynurenine is converted to 5-(2-Carboxyethyl)-4,6-Dihydroxypicolinate. The last reaction involves 5-(2-formylethyl)-4,6-Dihydroxypicolinate being converted into 5-(2-Carboxyethyl)-4,6-Dihydroxypicolinate by [E1.2.1.-].
Torcitabine
C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor C254 - Anti-Infective Agent > C281 - Antiviral Agent Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection treatment[1][2].
Koenoline
C14H13NO2 (227.09462380000002)
Koenoline is found in herbs and spices. Koenoline is an alkaloid from the root bark of Murraya koenigii (curryleaf tree). Alkaloid from the root bark of Murraya koenigii (curryleaf tree). Koenoline is found in herbs and spices.
Lansine
Lansine is found in fruits. Lansine is an alkaloid from the leaves of Clausena lansium (wampee
Mukoline
C14H13NO2 (227.09462380000002)
Mukoline is found in herbs and spices. Minor alkaloid from roots of Murraya koenigii (curryleaf tree). Minor alkaloid from roots of Murraya koenigii (curryleaf tree). Mukoline is found in herbs and spices.
Mukeic acid
Mukeic acid is found in herbs and spices. Mukeic acid is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree
1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane
C11H11Cl2N (227.02685060000002)
Cytosine deoxyribonucleoside
1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-imino-1,4-dihydropyrimidin-2-ol belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. Pyrimidine 2'-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-imino-1,4-dihydropyrimidin-2-ol is an extremely weak basic (essentially neutral) compound (based on its pKa). This compound has been identified in human blood as reported by (PMID: 31557052 ). Cytosine deoxyribonucleoside is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically Cytosine deoxyribonucleoside is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources. Cytosine deoxyribonucleoside, commonly referred to as deoxycytidine, is a nucleoside consisting of deoxyribose (a sugar) and cytosine (a nitrogenous base). It is an essential component of DNA and plays several critical roles in biological systems. Here is a detailed description of its biological functions: DNA Synthesis: Deoxycytidine is a key building block for the synthesis of DNA. During DNA replication, deoxycytidine is incorporated into the growing DNA strand as deoxycytidine monophosphate (dCMP), which is then converted to deoxycytidine triphosphate (dCTP) by cellular kinases. dCTP serves as a substrate for DNA polymerase, which adds deoxycytidine to the nascent DNA strand according to the base-pairing rule (cytosine pairs with guanine). DNA Repair: Deoxycytidine is involved in the DNA repair process. When DNA is damaged by environmental factors or errors during replication, repair mechanisms such as base excision repair, nucleotide excision repair, and mismatch repair utilize deoxycytidine to correct the lesions and restore the DNA to its original sequence. Genetic Coding: As part of the DNA molecule, deoxycytidine contributes to the genetic code. The sequence of nucleotides, including deoxycytidine, in DNA determines the sequence of amino acids in proteins, which ultimately dictates the structure and function of proteins and, consequently, the phenotype of the organism. Gene Expression: Deoxycytidine is also involved in gene expression. The presence of cytosine in specific sequences can lead to the formation of methyl groups (DNA methylation), which can regulate gene expression by either promoting or repressing the transcription of genes. Antiviral and Anticancer Therapy: Deoxycytidine analogs, such as cytarabine (ara-C) and zidovudine (AZT), are used in antiviral and anticancer therapies. These analogs can be incorporated into the viral or cancer cell DNA, leading to chain termination or other disruptions in DNA synthesis and function. Cellular Metabolism: Deoxycytidine can be phosphorylated to form deoxycytidine monophosphate (dCMP), deoxycytidine diphosphate (dCDP), and deoxycytidine triphosphate (dCTP). These phosphorylated forms are intermediates in the metabolic pathways of nucleotide synthesis and can be used for energy transfer within the cell. Nucleotide Pool Homeostasis: Deoxycytidine is part of the deoxynucleotide pool within the cell. Maintaining a balance of deoxynucleotides is crucial for various cellular processes, including DNA synthesis, repair, and regulation of gene expression. Enzymes such as nucleotide kinases, nucleotide phosphatases, and nucleoside transporters help regulate the levels of deoxycytidine and its phosphorylated forms.
Dexelvucitabine
C9H10FN3O3 (227.07061620000002)
Humic acid
D064449 - Sequestering Agents > D002614 - Chelating Agents > D006812 - Humic Substances
2-Nitro-alpha-((1-propenyloxy)methyl)imidazole-1-ethanol
N,N-dimethyl-N-(phenylsulfonyl)hydrazonoformamide
C9H13N3O2S (227.07284380000002)
2-[1-(4-chlorophenyl)ethylideneamino]oxyacetic Acid
3-[(4-chlorobenzoyl)amino]propanoic Acid
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3384
3-phenyl-3-(pyridin-2-yl)propanoic acid
C14H13NO2 (227.09462380000002)
7-Methoxy-6-methyl-9H-carbazol-3-ol
C14H13NO2 (227.09462380000002)
3-Methyl-6-methoxy-9H-carbazole-1-ol
C14H13NO2 (227.09462380000002)
4-amino-1-(3,5-dihydroxy-tetrahydro-pyran-2-yl)-1H-pyrimidin-2-one|Pentopyranin
N-methoxy-3-hydroxymethylcarbazole
C14H13NO2 (227.09462380000002)
5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione
6-[(methoxythio)carbonyl]pyridine-2-carboxylic acid methyl ester
5-(4-methoxymethylfuran-2-yl)-1H-indole|5-[4-(methoxymethyl)furan-2-yl]indole|raputimonoindole C
C14H13NO2 (227.09462380000002)
3,7-Dihydroxy-4-methyl-5H-indeno[1,2-b]pyridin-5-one
N-[2-(hydroxymethyl)phenyl]benzamide
C14H13NO2 (227.09462380000002)
7-hydroxy-1-methoxy-3-methylcarbazole
C14H13NO2 (227.09462380000002)
2-Methylaminobenzoic acid phenyl ester
C14H13NO2 (227.09462380000002)
1,7-Dihydroxyacridone
1,7-Dihydroxyacridone is a natural product found in Boronia lanceolata with data available.
Methyl 2-phenyl-2-(pyridin-2-yl)acetate
C14H13NO2 (227.09462380000002)
2-(4-aminophenyl)-2-phenylacetic acid
C14H13NO2 (227.09462380000002)
2-Deoxycytidine
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite A pyrimidine 2-deoxyribonucleoside having cytosine as the nucleobase. C26170 - Protective Agent > C2459 - Chemoprotective Agent COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.053 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
Deoxycytidine
2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
NPE_228.1019_12.4
C14H13NO2 (227.09462380000002)
CONFIDENCE Tentative identification: most likely structure (Level 3); INTERNAL_ID 1112
2-N-denrthyl-N-3-methylaplysinopsin
Origin: Animal; SubCategory_DNP: Aminoacids, Cyclic amino acids, Aromatic amino acids
(2-Aminophenyl)(3-methoxyphenyl)methanone
C14H13NO2 (227.09462380000002)
2-cyclohex-2-en-1-ylisoindole-1,3-dione
C14H13NO2 (227.09462380000002)
Methyl 4-amino-[1,1-biphenyl]-3-carboxylate
C14H13NO2 (227.09462380000002)
2-aminomethylbiphenyl-2-carboxylic acid
C14H13NO2 (227.09462380000002)
2-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE
[4-(trifluoromethoxy)phenyl]methanamine,hydrochloride
4-FLUORO-3-(METHOXY(METHYL)CARBAMOYL)PHENYLBORONIC ACID
4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-5-amine
Benzoic acid,2-[(2-chloroacetyl)amino]-, methyl ester
(2S,4S)-4-Phenylpyrrolidine-2-carboxylic acid hydrochloride
N-Isobutyltetrahydrothiophene-3-amine-1,1-dioxide hydrochloride
7-Methyl-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxylic acid
C14H13NO2 (227.09462380000002)
2-(1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL)ACETIC ACID HYDROCHLORIDE
3-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]pyridine
2-PYRIDIN-3-YL-BENZOIC ACID ETHYL ESTER
C14H13NO2 (227.09462380000002)
3,6-DIHYDRO-1-METHYL-3-METHYLENE-SPIRO[3H-INDOLE-3,2-[2H]PYRAN]-2(1H)-ONE
C14H13NO2 (227.09462380000002)
Ethyl 5-acetyl-2-amino-4-methylthiophene-3-carboxylate
METHYL 2-AMINO-2,3-DIHYDRO-1H-INDENE-2-CARBOXYLATE HYDROCHLORIDE
2-(2-chloroethyl)-3-hydroxy-2H-1,3-benzoxazin-4-one
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl) acetamide
8-FLUORO-10,11-DIHYDRO-BENZO[4,5]CYCLOHEPTA[1,2-B]PYRIDIN-5-ONE
Methyl 1,2,3,4-tetrahydroisoquinoline-4-carboxylate
3-Deoxycytidine
4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (3'-Deoxycytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
4-(Cyclopropylmethoxy)picolinimidamide hydrochloride
[1-(4-chloropyrimidin-2-yl)piperidin-3-yl]methanol
methyl 3-(2-methoxy-2-oxoethyl)-5-methyl-2-oxo-1,3-dihydropyrrole-4-carboxylate
2-PHENYL-4,5,6,7-TETRAHYDRO-ISOINDOLE-1,3-DIONE
C14H13NO2 (227.09462380000002)
METHYL 2-HYDROXY-5-METHOXY-3-NITROBENZENECARBOXYLATE
2-(2-FORMYL-1H-PYRROL-1-YL)-4-METHOXYNICOTINONITRILE
2-HYDROXY-N-METHYL-[1,1-BIPHENYL]-3-CARBOXAMIDE
C14H13NO2 (227.09462380000002)
4-HYDROXY-N-METHYL-[1,1-BIPHENYL]-3-CARBOXAMIDE
C14H13NO2 (227.09462380000002)
N-phenyl-N-prop-2-enylfuran-2-carboxamide
C14H13NO2 (227.09462380000002)
3-((TERT-BUTOXYCARBONYL)AMINO)FURAN-2-CARBOXYLIC ACID
5,6,7,8-tetrahydroacridine-9-carboxylate
C14H13NO2 (227.09462380000002)
2-[(4-METHYLPHENYL)AMINO]BENZOIC ACID
C14H13NO2 (227.09462380000002)
Thiocyanic acid,2-(2-naphthalenyl)-2-oxoethyl ester
Methyl 4-hydroxy-3-methoxy-5-nitrobenzenecarboxylate
6-CHLORO-N-ISOBUTYL-N-METHYLPYRIDAZINE-3-CARBOXAMIDE
Methyl 4-amino-[1,1-biphenyl]-4-carboxylate
C14H13NO2 (227.09462380000002)
N-(4-Chlorophenyl)-3-(hydroxyamino)-3-iminopropanamide
(1,2,3,4-Tetrahydro-2-isoquinolyl)acetic acid hydrochloride
METHYL 1,2,3,4-TETRAHYDROISOQUINOLINE-7-CARBOXYLATE HCL
2-AMINOINDAN-2-CARBOXYLIC ACID HYDROCHLORIDE
C14H13NO2 (227.09462380000002)
2-(3-Fluorophenyl)-4-thiazolidinecarboxylic acid
C10H10FNO2S (227.04162520000003)
Ethyl 4-amino-2-(ethylthio)-5-pyrimidinecarboxylate
C9H13N3O2S (227.07284380000002)
1-ethyl-3-methyl-4-nitro-1h-pyrazole-5-carboxylic acid ethyl ester
Pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione, 10-methyl-
2-Trifluoromethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine hydrochloride
C7H9ClF3N3 (227.04370600000001)
(2R)-(-)-1-BENZOYL-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE
C11H11Cl2N (227.02685060000002)
4-(1,2,3-THIADIAZOL-4-YL)BENZYLAMINE HYDROCHLORIDE
(3-Fluoro-4-((2-hydroxyethyl)carbamoyl)phenyl)boronic acid
Benzeneacetic acid, a-(phenylamino)-
C14H13NO2 (227.09462380000002)
Methyl 3-amino-3-biphenylcarboxylate
C14H13NO2 (227.09462380000002)
1-[(Ammoniooxy)methyl]-3-(trifluoromethyl)benzene chloride
METHYL 1,2,3,4-TETRAHYDROISOQUINOLINE-6-CARBOXYLATE HYDROCHLORIDE
2-ethyl-4-nitro-5-propylpyrazole-3-carboxylic acid
3-ETHYL-1-METHYL-4-NITRO-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
ethyl (3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetate
5-NITRO-2-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIMIDINE-4,6-DIOL
1,8-Dihydro-8,8-dimethylpyrano[2,3]quinolin-2-one
C14H13NO2 (227.09462380000002)
N-METHYL-N-[4-(TRIFLUOROMETHOXY)PHENYL]AMINE HYDROCHLORIDE
3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride
C7H9ClF3N3 (227.04370600000001)
Ethyl 2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
2-(4-FLUORO-PHENYL)-THIAZOLIDINE-4-CARBOXYLIC ACID
C10H10FNO2S (227.04162520000003)
7-(difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
(S)-2-(1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL)ACETIC ACID HYDROCHLORIDE
Methyl 3-amino-4-biphenylcarboxylate
C14H13NO2 (227.09462380000002)
2-(Methylamino)biphenyl-3-carboxylic acid
C14H13NO2 (227.09462380000002)
4-(Methylamino)biphenyl-3-carboxylic acid
C14H13NO2 (227.09462380000002)
3-(Methylamino)biphenyl-3-carboxylic acid
C14H13NO2 (227.09462380000002)
Carbamic acid,N-phenyl-,phenylmethyl ester
C14H13NO2 (227.09462380000002)
2-Amino-4,6-bis(difluoromethoxy)pyrimidine
C6H5F4N3O2 (227.03178780000002)
1-(6-amino-2,3-dihydro-1,4-benzodioxin-7-yl)-2-chloroethanone
1-fluoro-2,4,6-trimethylpyridinium tetrafluoroborate
2-chloro-1-(2,3-dihydro-1,4-benzothiazin-4-yl)ethanone
(NE)-N-[(4-phenylmethoxyphenyl)methylidene]hydroxylamine
C14H13NO2 (227.09462380000002)
4-(1-AMINOCYCLOPROPYL)BENZOIC ACID METHYL ESTER HYDROCHLORIDE
3-(4-CHLOROPHENYL)-5-HYDROXYMETHYL-2-OXAZOLIDINONE
2-(2-CHLORO-ETHYL)-5-FLUORO-ISOINDOLE-1,3-DIONE
C10H7ClFNO2 (227.01493240000002)
1,2,3,4-Tetrahydro-Quinoline-7-Carboxylic Acid Methyl Ester Hydrochloride
1-[(Ammoniooxy)methyl]-4-(trifluoromethyl)benzene chloride
(4-Chloro-3-(dimethylcarbamoyl)phenyl)boronic acid
METHYL 5-AMINO-2,3-DIHYDRO-1H-INDENE-1-CARBOXYLATE HYDROCHLORIDE
Ethyl (2S)-2-indolinecarboxylate hydrochloride (1:1)
Thieno[2,3-b]pyridine, 2,3-dihydro-6-methyl-4-phenyl- (9CI)
2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID HCL
3-ethyl-6-methyl-2-sulfanylidene-[1,3]thiazolo[4,5-d]pyrimidin-7-one
Methyl 1,2,3,4-tetrahydroquinoline-2-carboxylate hydrochloride
3-(Trifluoromethyl)-4,5,6,7-tetrahydro-3H-pyrazolo[3,4-c]pyridine hydrochloride
C7H9ClF3N3 (227.04370600000001)
(3-chloro-2-fluoro-5-(trifluoromethyl)phenyl)methanamine
4-Methylpyrimido[1,2-a]benzimidazole-3-carboxylic acid
(4-Fluoro-3-((2-hydroxyethyl)carbamoyl)phenyl)boronic acid
2-PIPERAZIN-1-YL-THIAZOLE-5-CARBOXYLIC ACID METHYL ESTER
C9H13N3O2S (227.07284380000002)
Potassium 4-(N,N-dimethylamino)phenyltrifluoroborate
1,2,3,4-tetrahydro-3-methyl-8-quinolinesulfonic acid
3-fluoro-4-(4-methyl-1H-pyrazol-1-yl)aniline
C10H11ClFN3 (227.06254879999997)
(S)-METHYL 3-AMINO-2,3-DIHYDRO-1H-INDENE-5-CARBOXYLATE HYDROCHLORIDE
6-Methyl-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydrochloride
7-Methyl-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydrochloride
(1r,4r)-4-((2-chloropyriMidin-4-yl)aMino)cyclohexanol
(3-CHLORO-4-(DIMETHYLCARBAMOYL)PHENYL)BORONIC ACID
cis-2-Phenyl-pyrrolidine-3-carboxylic acid hydrochloride
4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
C9H13N3O2S (227.07284380000002)
(R)-2-(1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL)ACETIC ACID HYDROCHLORIDE
4-oxo-3,5-dihydropyrrolo[2,3-c]quinoline-1-carboxamide
1-(4-chlorophenyl)-N-(2,2-dimethoxyethyl)methanimine
3-OXO-3-(3-METHYL-5-TRIFLUOROMETHYLPHENYL)-PROPIONITRILE
[3-fluoro-4-[methoxy(methyl)carbamoyl]phenyl]boronic acid
2-FLUORO-5-(METHOXY(METHYL)CARBAMOYL)PHENYLBORONIC ACID
methyl 4-(methylsulfanyl)-3-nitrobenzenecarboxylate
trans-4-Phenyl-pyrrolidine-3-carboxylic acid hydrochloride
4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
4-[5-(1H-1,2,4-Triazol-1-Ylmethyl)-1H-1,2,4-Triazol-3-yl]Pyridine
2-chloro-3-[2-(hydroxymethyl)pyrrolidin-1-yl]phenol
AMINO-(4-HYDROXY-3,5-DIMETHOXY-PHENYL)-ACETIC ACID
6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
Methyl 1,2,3,4-tetrahydroisoquinoline-5-carboxylate hydrochloride
Methyl 1,2,3,4-tetrahydro-8-isoquinolinecarboxylate hydrochloride (1:1)
2-(2-CHLORO-5-NITROPYRIDIN-4-YL)VINYL]DIMETHYLAMINE
Methyl 5-chloro-4-fluoro-1H-indole-2-carboxylate
C10H7ClFNO2 (227.01493240000002)
Osilodrostat
H - Systemic hormonal preparations, excl. sex hormones and insulins > H02 - Corticosteroids for systemic use > H02C - Antiadrenal preparations > H02CA - Anticorticosteroids C471 - Enzyme Inhibitor
Elvucitabine
C9H10FN3O3 (227.07061620000002)
C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97452 - Nucleoside Reverse Transcriptase Inhibitor D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents D009676 - Noxae > D000963 - Antimetabolites > D015224 - Dideoxynucleosides D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors C254 - Anti-Infective Agent > C281 - Antiviral Agent
Dexelvucitabine
C9H10FN3O3 (227.07061620000002)
C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97452 - Nucleoside Reverse Transcriptase Inhibitor D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents D009676 - Noxae > D000963 - Antimetabolites > D015224 - Dideoxynucleosides D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors C254 - Anti-Infective Agent > C281 - Antiviral Agent
Amitifadine
C11H11Cl2N (227.02685060000002)
C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent
4,4-Dimethyl-3,4-dihydro-2H-1,2-benzoselenazine
C10H13NSe (227.02131480000003)
1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7-(trifluoromethyl)-, (1R,5S)-
C12H12F3N (227.09217879999997)
CP-601927 is a selective α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist (Ki=1.2 nM; EC50=2.6 μM). CP-601927 shows good brain penetration and antidepressant-like properties[1][2].
(1R,2S)-2-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)cyclohexanecarboxylic acid
C9H13N3O2S (227.07284380000002)
4-(6,7-Dihydro-5h-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile
2-Nitro-alpha-((1-propenyloxy)methyl)imidazole-1-ethanol
4-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)butanoic acid
3-[(2,4-dioxo-1H-pyrimidine-6-carbonyl)amino]propanoic acid
1-(Dimethylamino)-3-[(4-fluorophenyl)methyl]thiourea
C10H14FN3S (227.08924159999998)
5-(1H-indol-3-ylmethylidene)imidazolidine-2,4-dione
(1R,8S)-3-(trifluoromethyl)tricyclo[6.2.1.02,7]undeca-2(7),3,5-trien-11-amine
C12H12F3N (227.09217879999997)
Procysbi
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent
4-[(3-Methylthiophen-2-yl)methylamino]-4-oxobutanoic acid
(1R,10aS)-1,4,10,10a-Tetrahydrophenazine-1-carboxylate
A monocarboxylic acid anion that is the conjugate base of (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.
2-(Hydroxymethyl)-3-(2-oxo-2-hydroxyethyl)-4-(3-oxo-3-hydroxypropyl)-1H-pyrrole
5-(2-carboxyethyl)-4,6-dioxo-1H-pyridine-2-carboxylic acid
2-[(3-Methyl-5-oxo-4-pyrazolyl)hydrazo]benzonitrile
7-Methoxy-3,5-dimethyl-2-thiazolo[4,5-d]pyrimidinethione
CP-601932
C12H12F3N (227.09217879999997)
CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21?nM; EC50=~ 3?μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21?nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS[1].
