Cysteamine (bitartrate) (BioDeep_00001028396)
代谢物信息卡片
Cysteamine (bitartrate)
化学式: C6H13NO6S (227.0463558)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CS)N.C(C(C(=O)O)O)(C(=O)O)O
InChI: 4H,1-3H2
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Marit Schwantje, Signe Mosegaard, Suzan J G Knottnerus, Jan Bert van Klinken, Ronald J Wanders, Henk van Lenthe, Jill Hermans, Lodewijk IJlst, Simone W Denis, Yorrick R J Jaspers, Sabine A Fuchs, Riekelt H Houtkooper, Sacha Ferdinandusse, Frédéric M Vaz. Tracer-based lipidomics enables the discovery of disease-specific candidate biomarkers in mitochondrial β-oxidation disorders.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2024 Feb; 38(4):e23478. doi:
10.1096/fj.202302163r. [PMID: 38372965] - Chen Sun, Jiaqi Liang, Jia Zheng, Shuyu Mao, Siyu Chen, Ainiwaer Aikemu, Chang Liu. Brown adipose Vanin-1 is required for the maintenance of mitochondrial homeostasis and prevents diet-induced metabolic dysfunction.
Molecular metabolism.
2024 Jan; 80(?):101884. doi:
10.1016/j.molmet.2024.101884. [PMID: 38246587] - Chao Chen, Yuhua Zuo, Hongmei Hu, Xue Li, Li Zhang, Dou Yang, Fasheng Liu, Xinjun Liao, Guanghua Xiong, Zigang Cao, Zilin Zhong, Yanlong Bi, Huiqiang Lu, Jianjun Chen. Hepatic lipid metabolism disorders and immunotoxicity induced by cysteamine in early developmental stages of zebrafish.
Toxicology.
2023 May; 493(?):153555. doi:
10.1016/j.tox.2023.153555. [PMID: 37236339] - Bianca R Silva, José R V Silva. Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development.
Animal reproduction science.
2022 Dec; 249(?):107186. doi:
10.1016/j.anireprosci.2022.107186. [PMID: 36638648] - Sang Mi Shim, Ha Rim Choi, Soon Chul Kwon, Hye Yeon Kim, Ki Woon Sung, Eui Jung Jung, Su Ran Mun, Tae Hyun Bae, Dong Hyun Kim, Yeon Sung Son, Chan Hoon Jung, Jihoon Lee, Min Jae Lee, Joo-Won Park, Yong Tae Kwon. The Cys-N-degron pathway modulates pexophagy through the N-terminal oxidation and arginylation of ACAD10.
Autophagy.
2022 Oct; ?(?):1-20. doi:
10.1080/15548627.2022.2126617. [PMID: 36184612] - Dona M Gunawardana, Karen C Heathcote, Emily Flashman. Emerging roles for thiol dioxygenases as oxygen sensors.
The FEBS journal.
2022 09; 289(18):5426-5439. doi:
10.1111/febs.16147. [PMID: 34346181] - Jennifer A Hollywood, Prasanna K Kallingappa, Pang Yuk Cheung, Renita M Martis, Sree Sreebhavan, Robert D 'Atiola, Aparajita Chatterjee, Emma J Buckels, Brya G Matthews, Paula M Lewis, Alan J Davidson. Cystinosin-deficient rats recapitulate the phenotype of nephropathic cystinosis.
American journal of physiology. Renal physiology.
2022 08; 323(2):F156-F170. doi:
10.1152/ajprenal.00277.2021. [PMID: 35695380] - Nour Elkhateeb, Rasha Selim, Neveen A Soliman, Fatma M Atia, Ihab Ibrahim Abouelwoun, Mohamed A Elmonem, Rasha Helmy. Clinical and neurophysiological characterization of early neuromuscular involvement in children and adolescents with nephropathic cystinosis.
Pediatric nephrology (Berlin, Germany).
2022 Jul; 37(7):1555-1566. doi:
10.1007/s00467-021-05343-x. [PMID: 34791528] - Francesco Emma, Giovanni Montini, Marco Pennesi, Licia Peruzzi, Enrico Verrina, Bianca Maria Goffredo, Fabrizio Canalini, David Cassiman, Silvia Rossi, Elena Levtchenko. Biomarkers in Nephropathic Cystinosis: Current and Future Perspectives.
Cells.
2022 06; 11(11):. doi:
10.3390/cells11111839. [PMID: 35681534] - Anita Csorba, Erika Maka, Attila Szabó, Kata Kelen, György Reusz, Zoltán Zsolt Nagy. Ocular treatment of cystinosis with eye drop containing cysteamine.
Orvosi hetilap.
2022 May; 163(21):846-852. doi:
10.1556/650.2022.32484. [PMID: 35598215] - Xiaokang Zhou, Nanji Zhang, Jie Zhang, Qichao Gu, Canjuan Dong, Bo Lin, Caixia Zou. Microbiome and fermentation parameters in the rumen of dairy buffalo in response to ingestion associated with a diet supplemented with cysteamine and hemp seed oil.
Journal of animal physiology and animal nutrition.
2022 May; 106(3):471-484. doi:
10.1111/jpn.13616. [PMID: 34397125] - Rika Kluck, Sophia Müller, Celina Jagodzinski, Katharina Hohenfellner, Anja Büscher, Markus J Kemper, Jun Oh, Heiko Billing, Julia Thumfart, Lutz T Weber, Birgit Acham-Roschitz, Klaus Arbeiter, Burkhard Tönshoff, Martina Hagenberg, Nele Kanzelmeyer, Leo Pavičić, Dieter Haffner, Miroslav Zivicnjak. Body growth, upper arm fat area, and clinical parameters in children with nephropathic cystinosis compared with other pediatric chronic kidney disease entities.
Journal of inherited metabolic disease.
2022 03; 45(2):192-202. doi:
10.1002/jimd.12473. [PMID: 34989402] - Qianqian Zhu, Jingjing Du, Suxiang Feng, Jianjun Li, Ran Yang, Lingbo Qu. Highly selective and sensitive detection of glutathione over cysteine and homocysteine with a turn-on fluorescent biosensor based on cysteamine-stabilized CdTe quantum dots.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Feb; 267(Pt 2):120492. doi:
10.1016/j.saa.2021.120492. [PMID: 34666265] - Elizabeth G Ames, Jess G Thoene. Programmed Cell Death in Cystinosis.
Cells.
2022 02; 11(4):. doi:
10.3390/cells11040670. [PMID: 35203319] - Oladele Afolabi, Babatunde Alabi, Temidayo Omobowale, Olufemi Oluranti, Olugbenga Iwalewa. Cysteamine mitigates torsion/detorsion-induced reperfusion injury via inhibition of apoptosis, oxidative stress and inflammatory responses in experimental rat model.
Andrologia.
2022 Feb; 54(1):e14243. doi:
10.1111/and.14243. [PMID: 34498746] - Borhan Shokrollahi, Abdullah Fazli, Salim Morammazi, Nazila Saadati, Hafiz Ishfaq Ahmad, Faiz-Ul Hassan. Cysteamine administration in lambs grazing on mountain pastures: Effects on the body weight, antioxidant capacity, thyroid hormones and growth hormone secretion.
Veterinary medicine and science.
2022 01; 8(1):328-335. doi:
10.1002/vms3.644. [PMID: 34587370] - R Masoudi, S Esmaeilkhanian, M Sharafi, Z Abdollahi, V Jafari, A Hatefi, F Zarei, N Asadzadeh, A Sadeghipanah, H J Barfourooshi, M H Banabazi. Cysteamine enhances quality and fertility potential of rooster semen in cooled storage.
Theriogenology.
2022 Jan; 177(?):29-33. doi:
10.1016/j.theriogenology.2021.09.023. [PMID: 34656834] - Tonino Alonzi, Alessandra Aiello, Linda Petrone, Saeid Najafi Fard, Manuela D'Eletto, Laura Falasca, Roberta Nardacci, Federica Rossin, Giovanni Delogu, Concetta Castilletti, Maria Rosaria Capobianchi, Giuseppe Ippolito, Mauro Piacentini, Delia Goletti. Cysteamine with In Vitro Antiviral Activity and Immunomodulatory Effects Has the Potential to Be a Repurposing Drug Candidate for COVID-19 Therapy.
Cells.
2021 12; 11(1):. doi:
10.3390/cells11010052. [PMID: 35011614] - Ahmed Reda, Koenraad Veys, Martine Besouw. Fertility in Cystinosis.
Cells.
2021 12; 10(12):. doi:
10.3390/cells10123539. [PMID: 34944047] - Francesco Emma, William Van't Hoff, Katharina Hohenfellner, Rezan Topaloglu, Marcella Greco, Gema Ariceta, Chiara Bettini, Detlef Bockenhauer, Koenraad Veys, Lars Pape, Sally Hulton, Suzanne Collin, Fatih Ozaltin, Aude Servais, Georges Deschênes, Robert Novo, Aurélia Bertholet-Thomas, Jun Oh, Elisabeth Cornelissen, Mirian Janssen, Dieter Haffner, Lucilla Ravà, Corinne Antignac, Olivier Devuyst, Patrick Niaudet, Elena Levtchenko. An international cohort study spanning five decades assessed outcomes of nephropathic cystinosis.
Kidney international.
2021 11; 100(5):1112-1123. doi:
10.1016/j.kint.2021.06.019. [PMID: 34237326] - Jongmin Ahn, Cristina Avonto, Amar G Chittiboyina, Ikhlas A Khan. Solvents effect on dansyl cysteamine depletion and reactivity classification of skin sensitizers: Tackling the challenges using binary solvent systems.
Journal of pharmacological and toxicological methods.
2021 Nov; 112(?):107116. doi:
10.1016/j.vascn.2021.107116. [PMID: 34403747] - Xinfang Xie, Li Gao, Pan Liu, Jicheng Lv, Wan-Hong Lu, Hong Zhang, Jing Jin. Propensity of IgA to self-aggregate via tailpiece cysteine-471 and treatment of IgA nephropathy using cysteamine.
JCI insight.
2021 10; 6(19):. doi:
10.1172/jci.insight.150551. [PMID: 34428184] - Arezoo Mohammadzadeh, Paria Pashazadeh-Panahi, Mohammad Hasanzadeh. Visual monitoring and optical recognition of digoxin by functionalized AuNPs and triangular AgNPs as efficient optical nano-probes.
Journal of molecular recognition : JMR.
2021 10; 34(10):e2917. doi:
10.1002/jmr.2917. [PMID: 34106492] - Heng Zhang, Qing Song, Guangjun Yu, Zhongcheng Cao, Xiaoming Qiang, Xiuxiu Liu, Yong Deng. Phthalimide-(N-alkylbenzylamine) cysteamide hybrids as multifunctional agents against Alzheimer's disease: Design, synthesis, and biological evaluation.
Chemical biology & drug design.
2021 10; 98(4):493-500. doi:
10.1111/cbdd.13905. [PMID: 34143938] - Feroz Ahmad, Robert D Mitchell, Tom Houben, Angela Palo, Tulasi Yadati, Andrew J Parnell, Ketan Patel, Ronit Shiri-Sverdlov, David S Leake. Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice.
Journal of the American Heart Association.
2021 09; 10(18):e017524. doi:
10.1161/jaha.120.017524. [PMID: 34493066] - Thomas Quinaux, Aurélia Bertholet-Thomas, Aude Servais, Olivia Boyer, Isabelle Vrillon, Julien Hogan, Sandrine Lemoine, Ségolène Gaillard, Candide Alioli, Sophie Vasseur, Cécile Acquaviva, Olivier Peyruchaud, Irma Machuca-Gayet, Justine Bacchetta. Response to Cysteamine in Osteoclasts Obtained from Patients with Nephropathic Cystinosis: A Genotype/Phenotype Correlation.
Cells.
2021 09; 10(9):. doi:
10.3390/cells10092498. [PMID: 34572146] - Christina van Stein, Sabrina Klank, Marianne Grüneberg, Chris Ottolenghi, Jürgen Grebe, Janine Reunert, Erik Harms, Thorsten Marquardt. A comparison of immediate release and delayed release cysteamine in 17 patients with nephropathic cystinosis.
Orphanet journal of rare diseases.
2021 09; 16(1):387. doi:
10.1186/s13023-021-01991-2. [PMID: 34521447] - Amer Jamalpoor, Charlotte Agh van Gelder, Fjodor A Yousef Yengej, Esther A Zaal, Sante P Berlingerio, Koenraad R Veys, Carla Pou Casellas, Koen Voskuil, Khaled Essa, Carola Me Ammerlaan, Laura Rita Rega, Reini En van der Welle, Marc R Lilien, Maarten B Rookmaaker, Hans Clevers, Judith Klumperman, Elena Levtchenko, Celia R Berkers, Marianne C Verhaar, Maarten Altelaar, Rosalinde Masereeuw, Manoe J Janssen. Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis.
EMBO molecular medicine.
2021 07; 13(7):e13067. doi:
10.15252/emmm.202013067. [PMID: 34165243] - Rezan Topaloglu. Nephropathic cystinosis: an update on genetic conditioning.
Pediatric nephrology (Berlin, Germany).
2021 06; 36(6):1347-1352. doi:
10.1007/s00467-020-04638-9. [PMID: 32564281] - Faranak Aghaz, Asad Vaisi-Raygani, Mozafar Khazaei, Elham Arkan. The Anti-oxidative Effects of Encapsulated Cysteamine During Mice In Vitro Matured Oocyte/Morula-Compact Stage Embryo Culture Model: a Comparison of High-Efficiency Nanocarriers for Hydrophilic Drug Delivery-a Pilot Study.
Reproductive sciences (Thousand Oaks, Calif.).
2021 05; 28(5):1290-1306. doi:
10.1007/s43032-020-00333-0. [PMID: 33030694] - Cécile L Berends, Lisa Pagan, Michiel J van Esdonk, Naomi B Klarenbeek, Kirsten R Bergmann, Matthijs Moerland, Vincent van der Wel, Saco J de Visser, Hans Büller, Frans de Loos, Wouter S de Vries, Hans Waals, Leo G J de Leede, Jacobus Burggraaf, Ingrid M C Kamerling. A novel sustained-release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers.
Pharmacology research & perspectives.
2021 04; 9(2):e00739. doi:
10.1002/prp2.739. [PMID: 33764642] - Kimberly P Newton, Joel E Lavine, Laura Wilson, Cynthia Behling, Miriam B Vos, Jean P Molleston, Philip Rosenthal, Tamir Miloh, Mark H Fishbein, Ajay K Jain, Karen F Murray, Jeffrey B Schwimmer. Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis.
Hepatology (Baltimore, Md.).
2021 03; 73(3):937-951. doi:
10.1002/hep.31317. [PMID: 32416645] - Segolene Gaillard, Laurent Roche, Sandrine Lemoine, Georges Deschênes, Denis Morin, Christine Vianey-Saban, Cécile Acquaviva-Bourdain, Bruno Ranchin, Justine Bacchetta, Behrouz Kassai, Patrice Nony, Eurielle Bodénan, Valérie Laudy, Cécile Rouges, Setareh Zarrabian, Fabien Subtil, Catherine Mercier, Pierre Cochat, Aurélia Bertholet-Thomas. Adherence to cysteamine in nephropathic cystinosis: A unique electronic monitoring experience for a better understanding. A prospective cohort study: CrYSTobs.
Pediatric nephrology (Berlin, Germany).
2021 03; 36(3):581-589. doi:
10.1007/s00467-020-04722-0. [PMID: 32901297] - Rachel Nora Kasimer, Craig B Langman. Adult complications of nephropathic cystinosis: a systematic review.
Pediatric nephrology (Berlin, Germany).
2021 02; 36(2):223-236. doi:
10.1007/s00467-020-04487-6. [PMID: 32016627] - Alessandra Fraternale, Carolina Zara, Tomas Di Mambro, Elisabetta Manuali, Domenica Anna Genovese, Luca Galluzzi, Aurora Diotallevi, Andrea Pompa, Francesca De Marchis, Patrizia Ambrogini, Erica Cesarini, Francesca Luchetti, Michaël Smietana, Kathy Green, Francesca Bartoccini, Mauro Magnani, Rita Crinelli. I-152, a supplier of N-acetyl-cysteine and cysteamine, inhibits immunoglobulin secretion and plasma cell maturation in LP-BM5 murine leukemia retrovirus-infected mice by affecting the unfolded protein response.
Biochimica et biophysica acta. Molecular basis of disease.
2020 12; 1866(12):165922. doi:
10.1016/j.bbadis.2020.165922. [PMID: 32800945] - Syed Mohammed Basheeruddin Asdaq, Earla Swathi, Sunil S Dhamanigi, Mohammed Asad, Yahya Ali Mohzari, Ahmed A Alrashed, Abdulrahman S Alotaibi, Batool Mohammed Alhassan, Sreeharsha Nagaraja. Role of Daucus carota in Enhancing Antiulcer Profile of Pantoprazole in Experimental Animals.
Molecules (Basel, Switzerland).
2020 Nov; 25(22):. doi:
10.3390/molecules25225287. [PMID: 33202703] - Han-Chiang Wu, Xing Fan, Chung-Hsuan Hu, Yi-Chun Chao, Chin-San Liu, Jui-Chih Chang, Yang Sen. Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Oct; 130(?):110520. doi:
10.1016/j.biopha.2020.110520. [PMID: 32707439] - Mahbubeh Moradkhani, Fatemeh Farshchi, Mohammad Hasanzadeh, Ahad Mokhtarzadeh. A novel bioassay for the monitoring of carcinoembryonic antigen in human biofluid using polymeric interface and immunosensing method.
Journal of molecular recognition : JMR.
2020 10; 33(10):e2852. doi:
10.1002/jmr.2852. [PMID: 32303119] - Seyyed Aliakbar Sheikholeslami, Ali Soleimanzadeh, Alaleh Rakhshanpour, Dariush Shirani. The evaluation of lycopene and cysteamine supplementation effects on sperm and oxidative stress parameters during chilled storage of canine semen.
Reproduction in domestic animals = Zuchthygiene.
2020 Sep; 55(9):1229-1239. doi:
10.1111/rda.13770. [PMID: 32644236] - Rezan Topaloglu, Ayşe Gültekingil, Bora Gülhan, Fatih Ozaltin, Hülya Demir, Türkmen Çiftci, Numan Demir, Çağrı Mesut Temucin, Aysel Yuce, Okhan Akhan. Cystinosis beyond kidneys: gastrointestinal system and muscle involvement.
BMC gastroenterology.
2020 Jul; 20(1):242. doi:
10.1186/s12876-020-01385-x. [PMID: 32727395] - Yifei Wang, Peter de B Harrington, Pei Chen. Quantitative analysis of proanthocyanidins in cocoa using cysteamine-induced thiolysis and reversed-phase UPLC.
Analytical and bioanalytical chemistry.
2020 Jul; 412(18):4343-4352. doi:
10.1007/s00216-020-02669-7. [PMID: 32372274] - Ewa Elenberg, Christine A O'Mahony, Karen W Eldin. Ruptured gallbladder in cystinosis renal transplant recipient.
Kidney international.
2020 06; 97(6):1304. doi:
10.1016/j.kint.2019.11.032. [PMID: 32444100] - Sahana Vasudevan, Parthasarathy Srinivasan, John Bosco Balaguru Rayappan, Adline Princy Solomon. A photoluminescence biosensor for the detection of N-acyl homoserine lactone using cysteamine functionalized ZnO nanoparticles for the early diagnosis of urinary tract infections.
Journal of materials chemistry. B.
2020 05; 8(19):4228-4236. doi:
10.1039/c9tb02243k. [PMID: 32330210] - Jennifer A Hollywood, Aneta Przepiorski, Randall F D'Souza, Sreevalsan Sreebhavan, Ernst J Wolvetang, Patrick T Harrison, Alan J Davidson, Teresa M Holm. Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis.
Journal of the American Society of Nephrology : JASN.
2020 05; 31(5):962-982. doi:
10.1681/asn.2019070712. [PMID: 32198276] - Koenraad R P Veys, Mohamed A Elmonem, Maria Van Dyck, Mirian C Janssen, Elisabeth A M Cornelissen, Katharina Hohenfellner, Giusi Prencipe, Lambertus P van den Heuvel, Elena Levtchenko. Chitotriosidase as a Novel Biomarker for Therapeutic Monitoring of Nephropathic Cystinosis.
Journal of the American Society of Nephrology : JASN.
2020 05; 31(5):1092-1106. doi:
10.1681/asn.2019080774. [PMID: 32273301] - Irma Machuca-Gayet, Thomas Quinaux, Aurélia Bertholet-Thomas, Ségolène Gaillard, Débora Claramunt-Taberner, Cécile Acquaviva-Bourdain, Justine Bacchetta. Bone Disease in Nephropathic Cystinosis: Beyond Renal Osteodystrophy.
International journal of molecular sciences.
2020 Apr; 21(9):. doi:
10.3390/ijms21093109. [PMID: 32354056] - Noelia Nikoloff, Anabella Campagna, Carolina Luchetti, Ana C Carranza-Martín, Ana M Pascua, Juan Mateo Anchordoquy, Juan Patricio Anchordoquy, Daniel M Lombardo, Analia Seoane, Cecilia C Furnus. Effects of EPA on bovine oocytes matured in vitro with antioxidants: Impact on the lipid content of oocytes and early embryo development.
Theriogenology.
2020 Apr; 146(?):152-161. doi:
10.1016/j.theriogenology.2019.11.028. [PMID: 31787466] - Pachara Thananurak, Napapach Chuaychu-Noo, Aurore Thélie, Yupin Phasuk, Thevin Vongpralub, Elisabeth Blesbois. Different concentrations of cysteamine, ergothioneine, and serine modulate quality and fertilizing ability of cryopreserved chicken sperm.
Poultry science.
2020 Feb; 99(2):1185-1198. doi:
10.1016/j.psj.2019.10.040. [PMID: 32029149] - Lingyuan Yang, Lingmei Zhang, Xingguo Huang, Yulong Yin, Tiejun Li, Jiashun Chen. Effects of Combined Supplementation of Conjugated Linoleic Acid, Methionine Chromium, Betaine, and Cysteamine on Meat Tenderness of Rats.
BioMed research international.
2020; 2020(?):5159796. doi:
10.1155/2020/5159796. [PMID: 32832551] - Domenico De Rasmo, Anna Signorile, Ester De Leo, Elena V Polishchuk, Anna Ferretta, Roberto Raso, Silvia Russo, Roman Polishchuk, Francesco Emma, Francesco Bellomo. Mitochondrial Dynamics of Proximal Tubular Epithelial Cells in Nephropathic Cystinosis.
International journal of molecular sciences.
2019 Dec; 21(1):. doi:
10.3390/ijms21010192. [PMID: 31888107] - Yichuan Wen, Feroz Ahmad, Zahra Mohri, Peter D Weinberg, David S Leake. Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice.
Atherosclerosis.
2019 12; 291(?):9-18. doi:
10.1016/j.atherosclerosis.2019.09.019. [PMID: 31629988] - Svetlana Papizh, Victoria Serzhanova, Alexandra Filatova, Mikhail Skoblov, Vyacheslav Tabakov, Lambert van den Heuvel, Elena Levtchenko, Larisa Prikhodina. CTNS mRNA molecular analysis revealed a novel mutation in a child with infantile nephropathic cystinosis: a case report.
BMC nephrology.
2019 10; 20(1):400. doi:
10.1186/s12882-019-1589-2. [PMID: 31672123] - James Blackburn, Renuka Ramakrishnan. Short stature: making a crystal clear diagnosis.
Journal of pediatric endocrinology & metabolism : JPEM.
2019 Oct; 32(10):1187-1191. doi:
10.1515/jpem-2019-0133. [PMID: 31600138] - Dan Yuan, Jia Jun Liu, Hui Hong Yan, Chun Mei Li, Cheng Zhi Huang, Jian Wang. Label-free gold nanorods sensor array for colorimetric detection and discrimination of biothiols in human urine samples.
Talanta.
2019 Oct; 203(?):220-226. doi:
10.1016/j.talanta.2019.05.076. [PMID: 31202329] - Peng Yan, Zhi Ding, Xizhe Li, Yanhua Dong, Tao Fu, Yayan Wu. Colorimetric Sensor Array Based on Wulff-Type Boronate Functionalized AgNPs at Various pH for Bacteria Identification.
Analytical chemistry.
2019 10; 91(19):12134-12137. doi:
10.1021/acs.analchem.9b03172. [PMID: 31475515] - Katharina Hohenfellner, Frank Rauch, Gema Ariceta, Atif Awan, Justine Bacchetta, Carsten Bergmann, Susanne Bechtold, Noelle Cassidy, Geroges Deschenes, Ewa Elenberg, William A Gahl, Oliver Greil, Erik Harms, Nadine Herzig, Bernd Hoppe, Christian Koeppl, Malcolm A Lewis, Elena Levtchenko, Galina Nesterova, Fernando Santos, Karl P Schlingmann, Aude Servais, Neveen A Soliman, Guenther Steidle, Clodagh Sweeney, Ulrike Treikauskas, Rezan Topaloglu, Alexey Tsygin, Koenraad Veys, Rodo V Vigier, Jozef Zustin, Dieter Haffner. Management of bone disease in cystinosis: Statement from an international conference.
Journal of inherited metabolic disease.
2019 09; 42(5):1019-1029. doi:
10.1002/jimd.12134. [PMID: 31177550] - Dandan Jiang, Zheng Li, Qiong Jia. A sensitive and selective phosphopeptide enrichment strategy by combining polyoxometalates and cysteamine hydrochloride-modified chitosan through layer-by-layer assembly.
Analytica chimica acta.
2019 Aug; 1066(?):58-68. doi:
10.1016/j.aca.2019.04.001. [PMID: 31027535] - Siewdorlang Diamai, Devendra P S Negi. Cysteine-stabilized silver nanoparticles as a colorimetric probe for the selective detection of cysteamine.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2019 May; 215(?):203-208. doi:
10.1016/j.saa.2019.02.101. [PMID: 30826579] - Li-Jun Sun, Lingbo Qu, Ran Yang, Lu Yin, Hua-Jin Zeng. Cysteamine functionalized MoS2 quantum dots inhibit amyloid aggregation.
International journal of biological macromolecules.
2019 May; 128(?):870-876. doi:
10.1016/j.ijbiomac.2019.01.212. [PMID: 30716371] - A E van Rijssel, S Knuijt, K Veys, E N Levtchenko, M C H Janssen. Swallowing dysfunction in patients with nephropathic cystinosis.
Molecular genetics and metabolism.
2019 04; 126(4):413-415. doi:
10.1016/j.ymgme.2019.01.011. [PMID: 30685240] - Qin Tu, Tianxi Yang, Yanqi Qu, Siyue Gao, Zhiyun Zhang, Qingmiao Zhang, Yilei Wang, Jinyi Wang, Lili He. In situ colorimetric detection of glyphosate on plant tissues using cysteamine-modified gold nanoparticles.
The Analyst.
2019 Mar; 144(6):2017-2025. doi:
10.1039/c8an02473a. [PMID: 30702090] - K Kuczborska, J Gozdowska, D Lewandowska, R Grenda, Z Gałązka, S Nazarewski, M Durlik. Therapeutic Problems and Pregnancy in a Patient With Infantile Nephropathic Cystinosis: A Case Report.
Transplantation proceedings.
2019 Mar; 51(2):545-547. doi:
10.1016/j.transproceed.2018.12.026. [PMID: 30879586] - Manish Bodas, Garrett Pehote, David Silverberg, Erich Gulbins, Neeraj Vij. Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation and COPD-emphysema pathogenesis.
Free radical biology & medicine.
2019 02; 131(?):81-97. doi:
10.1016/j.freeradbiomed.2018.11.023. [PMID: 30500419] - Feroz Ahmad, David S Leake. Lysosomal oxidation of LDL alters lysosomal pH, induces senescence, and increases secretion of pro-inflammatory cytokines in human macrophages.
Journal of lipid research.
2019 01; 60(1):98-110. doi:
10.1194/jlr.m088245. [PMID: 30397186] - N Liu, J Q Wang, Z Y Liu, Y K Chen, J P Wang. Effect of cysteamine hydrochloride supplementation on the growth performance, enterotoxic status, and glutathione turnover of broilers fed aflatoxin B1 contaminated diets.
Poultry science.
2018 Oct; 97(10):3594-3600. doi:
10.3382/ps/pey206. [PMID: 29850917] - Jessica Kaufeld, Lutz T Weber, Christine Kurschat, Sima Canaan-Kuehl, Eva Brand, Jun Oh, Lars Pape. [Cystinosis : Diagnosis, cystine-depleting therapy, and transition].
Der Internist.
2018 08; 59(8):861-867. doi:
10.1007/s00108-018-0416-3. [PMID: 29671012] - Daehwan Park, Jin Yong Lee, Heui Kyoung Cho, Woo Jin Hong, Jisun Kim, Hyemyung Seo, Ikjang Choi, Youngbok Lee, Juhyeon Kim, Sun-Joon Min, So-Hyun Yoon, Jae Sung Hwang, Kwang Jin Cho, Jin Woong Kim. Cell-Penetrating Peptide-Patchy Deformable Polymeric Nanovehicles with Enhanced Cellular Uptake and Transdermal Delivery.
Biomacromolecules.
2018 07; 19(7):2682-2690. doi:
10.1021/acs.biomac.8b00292. [PMID: 29847726] - Cristina Avonto, Amar G Chittiboyina, Nakissa Sadrieh, Stanislav Vukmanovic, Ikhlas A Khan. In chemico skin sensitization risk assessment of botanical ingredients.
Journal of applied toxicology : JAT.
2018 07; 38(7):1047-1053. doi:
10.1002/jat.3614. [PMID: 29572967] - Bashiyar Almarwani, Esther Nzuzi Phambu, Christopher Alexander, Ha Aimee T Nguyen, Nsoki Phambu, Anderson Sunda-Meya. Vesicles mimicking normal and cancer cell membranes exhibit differential responses to the cell-penetrating peptide Pep-1.
Biochimica et biophysica acta. Biomembranes.
2018 Jun; 1860(6):1394-1402. doi:
10.1016/j.bbamem.2018.03.022. [PMID: 29621495] - Michael S Middleton, Mark L Van Natta, Elhamy R Heba, Adina Alazraki, Andrew T Trout, Prakash Masand, Elizabeth M Brunt, David E Kleiner, Edward Doo, James Tonascia, Joel E Lavine, Wei Shen, Gavin Hamilton, Jeffrey B Schwimmer, Claude B Sirlin. Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease.
Hepatology (Baltimore, Md.).
2018 03; 67(3):858-872. doi:
10.1002/hep.29596. [PMID: 29028128] - Angela L Chiew, Christian Gluud, Jesper Brok, Nick A Buckley. Interventions for paracetamol (acetaminophen) overdose.
The Cochrane database of systematic reviews.
2018 02; 2(?):CD003328. doi:
10.1002/14651858.cd003328.pub3. [PMID: 29473717] - Paul Schutzmeier, Augusto Focil Baquerizo, Wilson Castillo-Tandazo, Nicholas Focil, Stephan Bose-O'Reilly. Efficacy of N,N'bis-(2-mercaptoethyl) isophthalamide on mercury intoxication: a randomized controlled trial.
Environmental health : a global access science source.
2018 02; 17(1):15. doi:
10.1186/s12940-018-0358-1. [PMID: 29444690] - Shaoyi Zhang, Gautier Stoll, José Manuel Bravo San Pedro, Valentina Sica, Allan Sauvat, Florine Obrist, Oliver Kepp, Yousheng Li, Luigi Maiuri, Naoufal Zamzami, Guido Kroemer. Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR.
Cell death & disease.
2018 02; 9(2):191. doi:
10.1038/s41419-017-0235-9. [PMID: 29415993] - Guilin Chen, Hui Feng, Xiaogan Jiang, Jing Xu, Saifei Pan, Zhaosheng Qian. Redox-Controlled Fluorescent Nanoswitch Based on Reversible Disulfide and Its Application in Butyrylcholinesterase Activity Assay.
Analytical chemistry.
2018 02; 90(3):1643-1651. doi:
10.1021/acs.analchem.7b02976. [PMID: 29298486] - Danielle Armas, Robert J Holt, Nils F Confer, Gregg C Checani, Mohammad Obaidi, Yuli Xie, Meg Brannagan. A Phase 1 Pharmacokinetic Study of Cysteamine Bitartrate Delayed-Release Capsules Following Oral Administration with Orange Juice, Water, or Omeprazole in Cystinosis.
Advances in therapy.
2018 02; 35(2):199-209. doi:
10.1007/s12325-018-0661-9. [PMID: 29411268] - Ambily Thomas, Unni Sivasankaran, Krishnapillai Girish Kumar. Biothiols induced colour change of silver nanoparticles: A colorimetric sensing strategy.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2018 Jan; 188(?):113-119. doi:
10.1016/j.saa.2017.06.040. [PMID: 28704805] - Paola Krall, Daniela Nualart, Jean Grandy. [Nephropatic cystinosis: report of one case].
Revista medica de Chile.
2018 Jan; 146(1):111-115. doi:
10.4067/s0034-98872018000100111. [PMID: 29806685] - Virginia C Rech, Nathana J Mezzomo, Genaro A Athaydes, Luciane R Feksa, Vandré C Figueiredo, Adriana Kessler, Itiane D DE Franceschi, Clovis M D Wannmacher. Thiol/disulfide status regulates the activity of thiol-containing kinases related to energy homeostasis in rat kidney.
Anais da Academia Brasileira de Ciencias.
2018 Jan; 90(1):99-108. doi:
10.1590/0001-3765201720160348. [PMID: 29236866] - Xiaowen Dou, Lei Zhang, Congmin Liu, Qian Li, Jiaoyang Luo, Meihua Yang. Fluorometric competitive immunoassay for chlorpyrifos using rhodamine-modified gold nanoparticles as a label.
Mikrochimica acta.
2017 12; 185(1):41. doi:
10.1007/s00604-017-2561-0. [PMID: 29594500] - Xin Li, Jing Huang, Matthew A Holden, Min Chen. Peptide-Mediated Membrane Transport of Macromolecular Cargo Driven by Membrane Asymmetry.
Analytical chemistry.
2017 11; 89(22):12369-12374. doi:
10.1021/acs.analchem.7b03421. [PMID: 29050472] - Yiming Hu, Hongyu Li, Wen Shi, Huimin Ma. Ratiometric Fluorescent Probe for Imaging of Pantetheinase in Living Cells.
Analytical chemistry.
2017 10; 89(20):11107-11112. doi:
10.1021/acs.analchem.7b03303. [PMID: 28911222] - Karutha Pandian Divya, Venkataraman Dharuman. Supported binary liposome vesicle-gold nanoparticle for enhanced label free DNA and protein sensing.
Biosensors & bioelectronics.
2017 Sep; 95(?):168-173. doi:
10.1016/j.bios.2017.04.022. [PMID: 28448961] - Teng-Fei Yuan, Shao-Ting Wang, Yan Li. Quantification of menadione from plasma and urine by a novel cysteamine-derivatization based UPLC-MS/MS method.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Sep; 1063(?):107-111. doi:
10.1016/j.jchromb.2017.08.026. [PMID: 28858751] - Manel Jellouli, Meriem Ferjani, Kamel Abidi, Chokri Zarrouk, Jaouida Abdelmoula, Tahar Gargah. Infantile cystinosis: From dialysis to renal transplantation.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2017 Sep; 28(5):1180-1183. doi:
10.4103/1319-2442.215119. [PMID: 28937083] - M Ambrogi, P C Dall'Acqua, Nas Rocha-Frigoni, Bcs Leão, G Z Mingoti. Transporting bovine oocytes in a medium supplemented with different macromolecules and antioxidants: Effects on nuclear and cytoplasmic maturation and embryonic development in vitro.
Reproduction in domestic animals = Zuchthygiene.
2017 Jun; 52(3):409-421. doi:
10.1111/rda.12923. [PMID: 28120355] - Fereshteh Chekin, Rabah Boukherroub, Sabine Szunerits. MoS2/reduced graphene oxide nanocomposite for sensitive sensing of cysteamine in presence of uric acid in human plasma.
Materials science & engineering. C, Materials for biological applications.
2017 Apr; 73(?):627-632. doi:
10.1016/j.msec.2016.12.102. [PMID: 28183654] - Haiyan Dong, Wenbo Chen, Chao Sun, Jianwei Sun, Yanlin Wang, Chao Xie, Qianwen Fu, Junjie Zhu, Jinyun Ye. Identification, characterization of selenoprotein W and its mRNA expression patterns in response to somatostatin 14, cysteamine hydrochloride, 17β-estradiol and a binary mixture of 17β-estradiol and cysteamine hydrochloride in topmouth culter (Erythroculter ilishaeformis).
Fish physiology and biochemistry.
2017 Feb; 43(1):115-126. doi:
10.1007/s10695-016-0272-9. [PMID: 27506211] - Yong Zhao, Yanni Feng, Hongfu Zhang, Xin Kou, Lan Li, Xinqi Liu, Pengfei Zhang, Liantao Cui, Meiqiang Chu, Wei Shen, Lingjiang Min. Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production.
Theriogenology.
2017 Feb; 89(?):280-288. doi:
10.1016/j.theriogenology.2016.11.014. [PMID: 28043364] - Camille M Hénault, John E Baenziger. Functional characterization of two prokaryotic pentameric ligand-gated ion channel chimeras - role of the GLIC transmembrane domain in proton sensing.
Biochimica et biophysica acta. Biomembranes.
2017 Feb; 1859(2):218-227. doi:
10.1016/j.bbamem.2016.11.006. [PMID: 27845033] - Dae Young Yoo, Dae Won Kim, Jin Young Chung, Hyo Young Jung, Jong Whi Kim, Yeo Sung Yoon, In Koo Hwang, Jung Hoon Choi, Goang-Min Choi, Soo Young Choi, Seung Myung Moon. Cu, Zn-Superoxide Dismutase Increases the Therapeutic Potential of Adipose-derived Mesenchymal Stem Cells by Maintaining Antioxidant Enzyme Levels.
Neurochemical research.
2016 Dec; 41(12):3300-3307. doi:
10.1007/s11064-016-2062-2. [PMID: 27743287] - Jeffrey B Schwimmer, Joel E Lavine, Laura A Wilson, Brent A Neuschwander-Tetri, Stavra A Xanthakos, Rohit Kohli, Sarah E Barlow, Miriam B Vos, Saul J Karpen, Jean P Molleston, Peter F Whitington, Philip Rosenthal, Ajay K Jain, Karen F Murray, Elizabeth M Brunt, David E Kleiner, Mark L Van Natta, Jeanne M Clark, James Tonascia, Edward Doo. In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores.
Gastroenterology.
2016 12; 151(6):1141-1154.e9. doi:
10.1053/j.gastro.2016.08.027. [PMID: 27569726] - Silvia Pescina, Marina Sala, Cristina Padula, Maria Carmina Scala, Antonia Spensiero, Silvana Belletti, Rita Gatti, Ettore Novellino, Pietro Campiglia, Patrizia Santi, Sara Nicoli, Carmine Ostacolo. Design and Synthesis of New Cell Penetrating Peptides: Diffusion and Distribution Inside the Cornea.
Molecular pharmaceutics.
2016 11; 13(11):3876-3883. doi:
10.1021/acs.molpharmaceut.6b00658. [PMID: 27676095] - Wei-Liang Chen, Shu-di Yang, Fang Li, Ji-Zhao Li, Zhi-Qiang Yuan, Wen-Jing Zhu, Yang Liu, Xiao-Feng Zhou, Chun Liu, Xue-Nong Zhang. Tumor microenvironment-responsive micelles for pinpointed intracellular release of doxorubicin and enhanced anti-cancer efficiency.
International journal of pharmaceutics.
2016 Sep; 511(2):728-40. doi:
10.1016/j.ijpharm.2016.07.060. [PMID: 27484835] - X Wang, Y X Zhao, H X Li, A J Li, S Liu, H M Chen, W Z Cui. [Effect of heme oxygenase-1 transduced by cell penetrating peptide PEP-1 on renal injury in rats with acute paraquat poisoning].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2016 Sep; 34(9):683-686. doi:
10.3760/cma.j.issn.1001-9391.2016.09.012. [PMID: 27866548] - Hongying Li, Xinxin Ye, Xisheng Guo, Zhigang Geng, Guozhong Wang. Effects of surface ligands on the uptake and transport of gold nanoparticles in rice and tomato.
Journal of hazardous materials.
2016 08; 314(?):188-196. doi:
10.1016/j.jhazmat.2016.04.043. [PMID: 27131459] - Graham Devereux, Sandra Steele, Kairen Griffiths, Edward Devlin, Douglas Fraser-Pitt, Seonaidh Cotton, John Norrie, Henry Chrystyn, Deborah O'Neil. An Open-Label Investigation of the Pharmacokinetics and Tolerability of Oral Cysteamine in Adults with Cystic Fibrosis.
Clinical drug investigation.
2016 Aug; 36(8):605-12. doi:
10.1007/s40261-016-0405-z. [PMID: 27153825] - Rodolfo Sumayao, Bernadette McEvoy, Philip Newsholme, Tara McMorrow. Lysosomal cystine accumulation promotes mitochondrial depolarization and induction of redox-sensitive genes in human kidney proximal tubular cells.
The Journal of physiology.
2016 06; 594(12):3353-70. doi:
10.1113/jp271858. [PMID: 26915455] - Koenraad R P Veys, Martine T P Besouw, Anne-Marie Pinxten, Maria Van Dyck, Ingele Casteels, Elena N Levtchenko. Cystinosis: a new perspective.
Acta clinica Belgica.
2016 Jun; 71(3):131-7. doi:
10.1179/2295333714y.0000000113. [PMID: 25560059] - Craig B Langman, Bruce A Barshop, Georges Deschênes, Francesco Emma, Paul Goodyer, Graham Lipkin, Julian P Midgley, Chris Ottolenghi, Aude Servais, Neveen A Soliman, Jess G Thoene, Elena N Levtchenko. Controversies and research agenda in nephropathic cystinosis: conclusions from a 'Kidney Disease: Improving Global Outcomes' (KDIGO) Controversies Conference.
Kidney international.
2016 06; 89(6):1192-203. doi:
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