2,3,4-Trinitrotoluene (BioDeep_00000173532)
human metabolite blood metabolite
代谢物信息卡片
1-methyl-2,3,4-trinitrobenzene
化学式: C7H5N3O6 (227.0178)
中文名称: 1-甲基-2,3,4-三硝基苯
谱图信息:
最多检出来源 Homo sapiens(general) 72.22%
分子结构信息
SMILES: CC1=C(C(=C(C=C1)[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-]
InChI: InChI=1S/C7H5N3O6/c1-4-2-3-5(8(11)12)7(10(15)16)6(4)9(13)14/h2-3H,1H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Mostafa Naderi, Mostafa Ghanei, Majid Shohrati, Amin Saburi, Mahmoud Babaei, Bita Najafian. Systemic complications of trinitrotoluene (TNT) in exposed workers.
Cutaneous and ocular toxicology.
2013 Mar; 32(1):31-4. doi:
10.3109/15569527.2012.699486. [PMID: 22994931] - Chao Wang, Mark E Fuller, Charles Schaefer, Jeffrey L Caplan, Yan Jin. Dissolution of explosive compounds TNT, RDX, and HMX under continuous flow conditions.
Journal of hazardous materials.
2012 May; 217-218(?):187-93. doi:
10.1016/j.jhazmat.2012.03.012. [PMID: 22480704] - Olga Muter, Katrina Potapova, Baiba Limane, Kristine Sproge, Ida Jakobsone, Guntis Cepurnieks, Vadims Bartkevics. The role of nutrients in the biodegradation of 2,4,6-trinitrotoluene in liquid and soil.
Journal of environmental management.
2012 May; 98(?):51-5. doi:
10.1016/j.jenvman.2011.12.010. [PMID: 22245864] - Jimmie C Oxley, James L Smith, Louis J Kirschenbaum, Suvarna Marimiganti, Irena Efremenko, Raya Zach, Yehuda Zeiri. Accumulation of explosives in hair--Part 3: Binding site study.
Journal of forensic sciences.
2012 May; 57(3):623-35. doi:
10.1111/j.1556-4029.2011.02020.x. [PMID: 22235760] - Steffen Ramin, Michael G Weller. Extremely sensitive and selective antibodies against the explosive 2,4,6-trinitrotoluene by rational design of a structurally optimized hapten.
Journal of molecular recognition : JMR.
2012 Feb; 25(2):89-97. doi:
10.1002/jmr.2162. [PMID: 22290770] - Peethambaran Arun, Samuel Oguntayo, Yonas Alamneh, Cary Honnold, Ying Wang, Manojkumar Valiyaveettil, Joseph B Long, Madhusoodana P Nambiar. Rapid release of tissue enzymes into blood after blast exposure: potential use as biological dosimeters.
PloS one.
2012; 7(4):e33798. doi:
10.1371/journal.pone.0033798. [PMID: 22493674] - Elaine N Ribeiro, Flávio Teixeira Da Silva, Teresa Cristina Brazil De Paiva. Ecotoxicological evaluation of wastewater from 2.4.6-TNT production.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2012; 47(2):184-91. doi:
10.1080/10934529.2012.640550. [PMID: 22242870] - Waraporn Jiamjitrpanich, Preeda Parkpian, Chongrak Polprasert, François Laurent, Rachain Kosanlavit. The tolerance efficiency of Panicum maximum and Helianthus annuus in TNT-contaminated soil and nZVI-contaminated soil.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2012; 47(11):1506-13. doi:
10.1080/10934529.2012.680320. [PMID: 22702809] - Elizabeth L Rylott, Maria V Budarina, Ann Barker, Astrid Lorenz, Stuart E Strand, Neil C Bruce. Engineering plants for the phytoremediation of RDX in the presence of the co-contaminating explosive TNT.
The New phytologist.
2011 Oct; 192(2):405-13. doi:
10.1111/j.1469-8137.2011.03807.x. [PMID: 21729248] - Elizabeth L Rylott, Astrid Lorenz, Neil C Bruce. Biodegradation and biotransformation of explosives.
Current opinion in biotechnology.
2011 Jun; 22(3):434-40. doi:
10.1016/j.copbio.2010.10.014. [PMID: 21094036] - Juan F Garcia-Reyes, Jason D Harper, Gary A Salazar, Nicholas A Charipar, Zheng Ouyang, R Graham Cooks. Detection of explosives and related compounds by low-temperature plasma ambient ionization mass spectrometry.
Analytical chemistry.
2011 Feb; 83(3):1084-92. doi:
10.1021/ac1029117. [PMID: 21174437] - E Nehrenheim, M Odlare, B Allard. Retention of 2,4,6-trinitrotoluene and heavy metals from industrial waste water by using the low cost adsorbent pine bark in a batch experiment.
Water science and technology : a journal of the International Association on Water Pollution Research.
2011; 64(10):2052-8. doi:
10.2166/wst.2011.603. [PMID: 22105128] - Youping Deng, David R Johnson, Xin Guan, Choo Y Ang, Junmei Ai, Edward J Perkins. In vitro gene regulatory networks predict in vivo function of liver.
BMC systems biology.
2010 Nov; 4(?):153. doi:
10.1186/1752-0509-4-153. [PMID: 21073692] - Premysl Landa, Helena Storchova, Jan Hodek, Radomira Vankova, Radka Podlipna, Petr Marsik, Jaroslava Ovesna, Tomas Vanek. Transferases and transporters mediate the detoxification and capacity to tolerate trinitrotoluene in Arabidopsis.
Functional & integrative genomics.
2010 Nov; 10(4):547-59. doi:
10.1007/s10142-010-0176-1. [PMID: 20532806] - Jennifer M Duringer, A Morrie Craig, David J Smith, Rufus L Chaney. Uptake and transformation of soil [14C]-trinitrotoluene by cool-season grasses.
Environmental science & technology.
2010 Aug; 44(16):6325-30. doi:
10.1021/es903671n. [PMID: 20666491] - Kristýna Sovová, Kseniya Dryahina, Patrik Spanel, Martin Kyncl, Svatopluk Civis. A study of the composition of the products of laser-induced breakdown of hexogen, octogen, pentrite and trinitrotoluene using selected ion flow tube mass spectrometry and UV-Vis spectrometry.
The Analyst.
2010 May; 135(5):1106-14. doi:
10.1039/b926425f. [PMID: 20419263] - Padmini Das, Rupali Datta, Konstantinos C Makris, Dibyendu Sarkar. Vetiver grass is capable of removing TNT from soil in the presence of urea.
Environmental pollution (Barking, Essex : 1987).
2010 May; 158(5):1980-3. doi:
10.1016/j.envpol.2009.12.011. [PMID: 20047780] - Laura B Brentner, Sachiyo T Mukherji, Susan A Walsh, Jerald L Schnoor. Localization of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and 2,4,6-trinitrotoluene (TNT) in poplar and switchgrass plants using phosphor imager autoradiography.
Environmental pollution (Barking, Essex : 1987).
2010 Feb; 158(2):470-5. doi:
10.1016/j.envpol.2009.08.022. [PMID: 19782446] - Konstantinos C Makris, Dibyendu Sarkar, Rupali Datta. Coupling indigenous biostimulation and phytoremediation for the restoration of 2,4,6-trinitrotoluene-contaminated sites.
Journal of environmental monitoring : JEM.
2010 Feb; 12(2):399-403. doi:
10.1039/b908162c. [PMID: 20145878] - John Mitchell. Small molecule immunosensing using surface plasmon resonance.
Sensors (Basel, Switzerland).
2010; 10(8):7323-46. doi:
10.3390/s100807323. [PMID: 22163605] - Murali R Rao, Matthew D Halfhill, Laura G Abercrombie, Priya Ranjan, Jason M Abercrombie, Julia S Gouffon, Arnold M Saxton, C Neal Stewart. Phytoremediation and phytosensing of chemical contaminants, RDX and TNT: identification of the required target genes.
Functional & integrative genomics.
2009 Nov; 9(4):537-47. doi:
10.1007/s10142-009-0125-z. [PMID: 19543758] - Suzanne C Bell, Melissa Gayton-Ely, Corey M Nida. Bioassays for bomb-makers: proof of concept.
Analytical and bioanalytical chemistry.
2009 Sep; 395(2):401-9. doi:
10.1007/s00216-009-2851-4. [PMID: 19484462] - Emily R Beynon, Zoe C Symons, Rosamond G Jackson, Astrid Lorenz, Elizabeth L Rylott, Neil C Bruce. The role of oxophytodienoate reductases in the detoxification of the explosive 2,4,6-trinitrotoluene by Arabidopsis.
Plant physiology.
2009 Sep; 151(1):253-61. doi:
10.1104/pp.109.141598. [PMID: 19605548] - Martina McGuinness, David Dowling. Plant-associated bacterial degradation of toxic organic compounds in soil.
International journal of environmental research and public health.
2009 08; 6(8):2226-47. doi:
10.3390/ijerph6082226. [PMID: 19742157] - Yan Zhang, Xiaoxiao Ma, Sichun Zhang, Chengdui Yang, Zheng Ouyang, Xinrong Zhang. Direct detection of explosives on solid surfaces by low temperature plasma desorption mass spectrometry.
The Analyst.
2009 Jan; 134(1):176-81. doi:
10.1039/b816230a. [PMID: 19082190] - M Gogoberidze, G Zaalishvili, M Ramishvili, M Gogava, N Chelidze. [Ultrastructural study of TNT effect on the callus cells and the cells of intact plants of Yucca gloriosa L].
TSitologiia i genetika.
2009 Jan; 43(1):23-7. doi:
". [PMID: 19663311] - Husain Qayyum, Husain Maroof, Kulshrestha Yasha. Remediation and treatment of organopollutants mediated by peroxidases: a review.
Critical reviews in biotechnology.
2009; 29(2):94-119. doi:
10.1080/07388550802685306. [PMID: 19514892] - Fernando Gandia-Herrero, Astrid Lorenz, Tony Larson, Ian A Graham, Dianna J Bowles, Elizabeth L Rylott, Neil C Bruce. Detoxification of the explosive 2,4,6-trinitrotoluene in Arabidopsis: discovery of bifunctional O- and C-glucosyltransferases.
The Plant journal : for cell and molecular biology.
2008 Dec; 56(6):963-74. doi:
10.1111/j.1365-313x.2008.03653.x. [PMID: 18702669] - Olga Muter, Aleksandrs Versilovskis, Rita Scherbaka, Mara Grube, Dzidra Zarina. Effect of plant extract on the degradation of nitroaromatic compounds by soil microorganisms.
Journal of industrial microbiology & biotechnology.
2008 Nov; 35(11):1539-43. doi:
10.1007/s10295-008-0455-1. [PMID: 18712534] - Laura B Brentner, Sachiyo T Mukherji, Kate M Merchie, Jong Moon Yoon, Jerald L Schnoor, Benoit Van Aken. Expression of glutathione S-transferases in poplar trees (Populus trichocarpa) exposed to 2,4,6-trinitrotoluene (TNT).
Chemosphere.
2008 Oct; 73(5):657-62. doi:
10.1016/j.chemosphere.2008.07.059. [PMID: 18774158] - Pieter Van Dillewijn, José L Couselo, Elena Corredoira, Antonio Delgado, Rolf-Michael Wittich, Antonio Ballester, Juan L Ramos. Bioremediation of 2,4,6-trinitrotoluene by bacterial nitroreductase expressing transgenic aspen.
Environmental science & technology.
2008 Oct; 42(19):7405-10. doi:
10.1021/es801231w. [PMID: 18939578] - Norka E Paden, Ernest E Smith, Ronald J Kendall. Acute toxicity of 2,4,6-trinitrotoluene, 2,4-dinitrotoluene, and 2,6-dinitrotoluene in the adult bullfrog (Lithobates catesbeiana).
Bulletin of environmental contamination and toxicology.
2008 Jun; 80(6):487-91. doi:
10.1007/s00128-008-9467-9. [PMID: 18551238] - Craig A McFarland, Michael J Quinn, Matthew A Bazar, Amera K Remick, Larry G Talent, Mark S Johnson. Toxicity of oral exposure to 2,4,6-trinitrotoluene in the western fence lizard (Sceloporus occidentalis).
Environmental toxicology and chemistry.
2008 May; 27(5):1102-11. doi:
10.1897/07-312.1. [PMID: 18419183] - Emma R Travis, Neil C Bruce, Susan J Rosser. Microbial and plant ecology of a long-term TNT-contaminated site.
Environmental pollution (Barking, Essex : 1987).
2008 May; 153(1):119-26. doi:
10.1016/j.envpol.2007.07.015. [PMID: 17825462] - Brittany R Flokstra, Benoit Van Aken, Jerald L Schnoor. Microtox toxicity test: detoxification of TNT and RDX contaminated solutions by poplar tissue cultures.
Chemosphere.
2008 May; 71(10):1970-6. doi:
10.1016/j.chemosphere.2007.12.020. [PMID: 18400248] - D J Smith, A M Craig, J M Duringer, R L Chaney. Absorption, tissue distribution, and elimination of residues after 2,4,6-trinitro[14C]toluene administration to sheep.
Environmental science & technology.
2008 Apr; 42(7):2563-9. doi:
10.1021/es702601n. [PMID: 18504997] - M Vila, S Lorber-Pascal, F Laurent. Phytotoxicity to and uptake of TNT by rice.
Environmental geochemistry and health.
2008 Apr; 30(2):199-203. doi:
10.1007/s10653-008-9145-1. [PMID: 18266057] - Helene Ek, Eva Nilsson, Göran Dave. Effects of TNT leakage from dumped ammunition on fish and invertebrates in static brackish water systems.
Ecotoxicology and environmental safety.
2008 Jan; 69(1):104-11. doi:
10.1016/j.ecoenv.2006.12.016. [PMID: 17292471] - S Fallahi, M Habibi-Rezaei, M Khayami, R Heydari. Soil decontamination of 2,4,6- trinitrotoluene by alfalfa (Medicago sativa).
Pakistan journal of biological sciences : PJBS.
2007 Dec; 10(24):4406-12. doi:
10.3923/pjbs.2007.4406.4412. [PMID: 19093503] - Gabriele Sabbioni, Richard Rumler. Biomonitoring of workers cleaning up ammunition waste sites.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2007 Nov; 12(6):559-73. doi:
10.1080/13547500701456206. [PMID: 17852074] - Insook Lee, Kyunghwa Baek, Hyunhee Kim, Sunghyun Kim, Jaisoo Kim, Youngseok Kwon, Yoontoung Chang, Bumhan Bae. Phytoremediation of soil co-contaminated with heavy metals and TNT using four plant species.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2007 Nov; 42(13):2039-45. doi:
10.1080/10934520701629781. [PMID: 17990167] - Ying Ouyang, Cheng He Huang, Dong Yi Huang, Dian Lin, Lihua Cui. Simulating uptake and transport of TNT by plants using STELLA.
Chemosphere.
2007 Oct; 69(8):1245-52. doi:
10.1016/j.chemosphere.2007.05.081. [PMID: 17655913] - Nerissa K Hannink, Murali Subramanian, Susan J Rosser, Amrik Basran, James A H Murray, Jacqueline V Shanks, Neil C Bruce. Enhanced transformation of tnt by tobacco plants expressing a bacterial nitroreductase.
International journal of phytoremediation.
2007 Sep; 9(5):385-401. doi:
10.1080/15226510701603916. [PMID: 18246725] - Mario Kröger, Gregor Fels. Combined biological-chemical procedure for the mineralization of TNT.
Biodegradation.
2007 Aug; 18(4):413-25. doi:
10.1007/s10532-006-9076-4. [PMID: 17091348] - Konstantinos C Makris, Kabindra M Shakya, Rupali Datta, Dibyendu Sarkar, Devanand Pachanoor. Chemically catalyzed uptake of 2,4,6-trinitrotoluene by Vetiveria zizanioides.
Environmental pollution (Barking, Essex : 1987).
2007 Jul; 148(1):101-6. doi:
10.1016/j.envpol.2006.10.047. [PMID: 17240499] - M Vila, S Lorber-Pascal, F Laurent. Fate of RDX and TNT in agronomic plants.
Environmental pollution (Barking, Essex : 1987).
2007 Jul; 148(1):148-54. doi:
10.1016/j.envpol.2006.10.030. [PMID: 17254682] - Helene Ek, Eva Nilsson, Göran Birgersson, Göran Dave. TNT leakage through sediment to water and toxicity to Nitocra spinipes.
Ecotoxicology and environmental safety.
2007 Jul; 67(3):341-8. doi:
10.1016/j.ecoenv.2006.10.011. [PMID: 17141867] - Jong Sung Kim, Patrick J Shea, Jae E Yang, Jang-Eok Kim. Halide salts accelerate degradation of high explosives by zerovalent iron.
Environmental pollution (Barking, Essex : 1987).
2007 Jun; 147(3):634-41. doi:
10.1016/j.envpol.2006.10.010. [PMID: 17241724] - Steven T Galluccio, Nicholas A Edwards, David Ge Caldicott, John E Greenwood. Methaemoglobinaemia: an explosive case.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.
2007 Jun; 9(2):178-80. doi:
". [PMID: 17536988] - Brandon Clark, Raj Boopathy. Evaluation of bioremediation methods for the treatment of soil contaminated with explosives in Louisiana Army Ammunition Plant, Minden, Louisiana.
Journal of hazardous materials.
2007 May; 143(3):643-8. doi:
10.1016/j.jhazmat.2007.01.034. [PMID: 17289260] - G Sabbioni, O Sepai, H Norppa, H Yan, A Hirvonen, Y Zheng, H Järventaus, B Bäck, L R Brooks, S H Warren, D M Demarini, Y Y Liu. Comparison of biomarkers in workers exposed to 2,4,6-trinitrotoluene.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2007 Jan; 12(1):21-37. doi:
10.1080/13547500600807012. [PMID: 17438651] - Sachiyo Tanaka, Laura B Brentner, Kate M Merchie, Jerald L Schnoor, Jong Moon Yoon, Benoit Van Aken. Analysis of gene expression in poplar trees (Populus deltoides x nigra, DN34) exposed to the toxic explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX).
International journal of phytoremediation.
2007 Jan; 9(1):15-30. doi:
10.1080/15226510601139375. [PMID: 18246712] - Hermann M Bolt, Gisela H Degen, Susanne B Dorn, Sabine Plöttner, Volker Harth. Genotoxicity and potential carcinogenicity of 2,4,6-TNT trinitrotoluene: structural and toxicological considerations.
Reviews on environmental health.
2006 Oct; 21(4):217-28. doi:
10.1515/reveh.2006.21.4.217. [PMID: 17243348] - Helene Ek, Göran Dave, Eva Nilsson, Joachim Sturve, Göran Birgersson. Fate and effects of 2,4,6-trinitrotoluene (TNT) from dumped ammunition in a field study with fish and invertebrates.
Archives of environmental contamination and toxicology.
2006 Aug; 51(2):244-52. doi:
10.1007/s00244-005-0117-5. [PMID: 16783622] - Nadia Ait Ali, David Dewez, Pierre Yves Robidoux, Radovan Popovic. Photosynthetic parameters as indicators of trinitrotoluene (TNT) inhibitory effect: change in chlorophyll a fluorescence induction upon exposure of lactuca sativa to TNT.
Ecotoxicology (London, England).
2006 Jul; 15(5):437-41. doi:
10.1007/s10646-006-0065-5. [PMID: 16721675] - G Adamia, M Ghoghoberidze, D Graves, G Khatisashvili, G Kvesitadze, E Lomidze, D Ugrekhelidze, G Zaalishvili. Absorption, distribution, and transformation of TNT in higher plants.
Ecotoxicology and environmental safety.
2006 Jun; 64(2):136-45. doi:
10.1016/j.ecoenv.2005.05.001. [PMID: 16002139] - Kyung-Hwa Baek, Joo-Yun Chang, Yoon-Young Chang, Bum-Han Bae, Jaisoo Kim, In-Sook Lee. Phytoremediation of soil contaminated with cadmium and/or 2,4,6-trinitrotoluene.
Journal of environmental biology.
2006 May; 27(2 Suppl):311-6. doi:
. [PMID: 17436516] - Christopher F Hoehamer, N Lee Wolfe, Karl Erik L Eriksson. Biotransformation of 2,4,6-trinitrotoluene (TNT) by the fungus Fusarium oxysporum.
International journal of phytoremediation.
2006; 8(2):95-105. doi:
10.1080/15226510600678423. [PMID: 16924959] - Murali Subramanian, David J Oliver, Jacqueline V Shanks. TNT phytotransformation pathway characteristics in Arabidopsis: role of aromatic hydroxylamines.
Biotechnology progress.
2006 Jan; 22(1):208-16. doi:
10.1021/bp050241g. [PMID: 16454512] - Jong Moon Yoon, Benoit Van Aken, Jerald L Schnoor. Leaching of contaminated leaves following uptake and phytoremediation of RDX, HMX, and TNT by poplar.
International journal of phytoremediation.
2006; 8(1):81-94. doi:
10.1080/15226510500507128. [PMID: 16615309] - Christopher F Hoehamer, N Lee Wolfe, Karl Erik L Eriksson. Differences in the biotransformation of 2,4,6-trinitrotoluene (TNT) between wild and axenically grown isolates of Myriophyllum aquaticum.
International journal of phytoremediation.
2006; 8(2):107-15. doi:
10.1080/15226510600678431. [PMID: 16924960] - A Nepovim, A Hebner, P Soudek, A Gerth, H Thomas, S Smrcek, T Vanek. Degradation of 2,4,6-trinitrotoluene by selected helophytes.
Chemosphere.
2005 Sep; 60(10):1454-61. doi:
10.1016/j.chemosphere.2005.01.073. [PMID: 16054915] - Y Ouyang, D Shinde, L Q Ma. Simulation of phytoremediation of a TNT-contaminated soil using the CTSPAC model.
Journal of environmental quality.
2005 Sep; 34(5):1490-6. doi:
10.2134/jeq2004.0471. [PMID: 16091601] - Drew R Ekman, N Lee Wolfe, Jeffrey F D Dean. Gene expression changes in Arabidopsis thaliana seedling roots exposed to the munition hexahydro-1,3,5-trinitro-1,3,5-triazine.
Environmental science & technology.
2005 Aug; 39(16):6313-20. doi:
10.1021/es050385r. [PMID: 16173598] - Gabriele Sabbioni, Yu-Ying Liu, Huifang Yan, Ovnair Sepai. Hemoglobin adducts, urinary metabolites and health effects in 2,4,6-trinitrotoluene exposed workers.
Carcinogenesis.
2005 Jul; 26(7):1272-9. doi:
10.1093/carcin/bgi078. [PMID: 15817613] - Mark S Johnson, Mark W Michie, Matthew A Bazar, Christopher J Salice, Robert M Gogal. Responses of oral 2,4,6-trinitrotoluene (TNT) exposure to the common pigeon (Columba livia): a phylogenic and methodological comparison.
International journal of toxicology.
2005 Jul; 24(4):221-9. doi:
10.1080/10915810591000686. [PMID: 16126616] - Melissa P Mezzari, Katherine Walters, Marcela Jelínkova, Ming-Che Shih, Craig L Just, Jerald L Schnoor. Gene expression and microscopic analysis of Arabidopsis exposed to chloroacetanilide herbicides and explosive compounds. A phytoremediation approach.
Plant physiology.
2005 Jun; 138(2):858-69. doi:
10.1104/pp.104.056168. [PMID: 15923336] - Mami Kurumata, Misa Takahashi, Atsushi Sakamotoa, Juan L Ramos, Ales Nepovim, Tomas Vanek, Toshifumi Hirata, Hiromichi Morikawa. Tolerance to, and uptake and degradation of 2,4,6-trinitrotoluene (TNT) are enhanced by the expression of a bacterial nitroreductase gene in Arabidopsis thaliana.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2005 Mar; 60(3-4):272-8. doi:
10.1515/znc-2005-3-412. [PMID: 15948595] - C R Jones, O Sepai, Y Y Liu, H Yan, G Sabbioni. Urinary metabolites of workers exposed to nitrotoluenes.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2005 Jan; 10(1):10-28. doi:
10.1080/13547500500079670. [PMID: 16097390] - Viktor Vorísek, Milan Pour, Karel Ubik, Valerie Hassmanová, Eva Korolová, Lukás Cerveny, Jirí Kunes, Vladimír Palicka. Analytical monitoring of trinitrotoluene metabolites in urine by GC-MS. Part I. Semiquantitative determination of 4-amino-2,6-dinitrotoluene in human urine.
Journal of analytical toxicology.
2005 Jan; 29(1):62-5. doi:
10.1093/jat/29.1.62. [PMID: 15808016] - Gian Gupta, Hemalatha Bhaskaran. Use of poultry litter for biodegradation of soil contaminated with 2,4- and 2,6-dinitrotoluene.
Journal of hazardous materials.
2004 Dec; 116(1-2):167-71. doi:
10.1016/j.jhazmat.2004.09.007. [PMID: 15561375] - Jaisoo Kim, Kijune Sung, M Yavuz Corapcioglu, Malcolm C Drew. Solute transport and extraction by a single root in unsaturated soils: model development and experiment.
Environmental pollution (Barking, Essex : 1987).
2004 Sep; 131(1):61-70. doi:
10.1016/j.envpol.2004.02.026. [PMID: 15210276] - Mario Kröger, Martina E Schumacher, Heike Risse, Gregor Fels. Biological reduction of TNT as part of a combined biological-chemical procedure for mineralization.
Biodegradation.
2004 Aug; 15(4):241-8. doi:
10.1023/b:biod.0000042914.53688.63. [PMID: 15473553] - Jonas Sarlauskas, Ausra Nemeikaite-Ceniene, Zilvinas Anusevicius, Lina Miseviciene, Marta Martinez Julvez, Milagros Medina, Carlos Gomez-Moreno, Narimantas Cenas. Flavoenzyme-catalyzed redox cycling of hydroxylamino- and amino metabolites of 2,4,6-trinitrotoluene: implications for their cytotoxicity.
Archives of biochemistry and biophysics.
2004 May; 425(2):184-92. doi:
10.1016/j.abb.2004.02.043. [PMID: 15111126] - Jonas Sarlauskas, Ausra Nemeikaite-Ceniene, Zilvinas Anusevicius, Lina Miseviciene, Audrone Maroziene, Arvydas Markevicius, Narimantas Cenas. Enzymatic redox properties of novel nitrotriazole explosives implications for their toxicity.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2004 May; 59(5-6):399-404. doi:
10.1515/znc-2004-5-620. [PMID: 18998409] - Victor F Medina, Steven L Larson, Lovell Agwaramgbo, Waleska Perez, Lynn Escalon. Treatment of trinitrotoluene by crude plant extracts.
Chemosphere.
2004 May; 55(5):725-32. doi:
10.1016/j.chemosphere.2003.12.014. [PMID: 15013677] - Allen M Orville, Linda Manning, David S Blehert, Joey M Studts, Brian G Fox, Glenn H Chambliss. Crystallization and preliminary analysis of xenobiotic reductase A and ligand complexes from Pseudomonas putida II-B.
Acta crystallographica. Section D, Biological crystallography.
2004 May; 60(Pt 5):957-61. doi:
10.1107/s0907444904006158. [PMID: 15103152] - Jeffrey M Weiss, Amanda J McKay, Christopher Derito, Chuichi Watanabe, Kevin A Thorn, Eugene L Madsen. Development and application of pyrolysis gas chromatography/mass spectrometry for the analysis of bound trinitrotoluene residues in soil.
Environmental science & technology.
2004 Apr; 38(7):2167-74. doi:
10.1021/es034911v. [PMID: 15112821] - Jaisoo Kim, Malcolm C Drew, M Yavuz Corapcioglu. Uptake and phytotoxicity of TNT in onion plant.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2004; 39(3):803-19. doi:
10.1081/ese-120027743. [PMID: 15055943] - Bernd W Schoenmuth, Wilfried Pestemer. Dendroremediation of trinitrotoluene (TNT). Part 2: fate of radio-labelled TNT in trees.
Environmental science and pollution research international.
2004; 11(5):331-9. doi:
10.1007/bf02979648. [PMID: 15506637] - Bernd W Schoenmuth, Wilfried Pestemer. Dendroremediation of trinitrotoluene (TNT). Part 1: Literature overview and research concept.
Environmental science and pollution research international.
2004; 11(4):273-8. doi:
10.1007/bf02979637. [PMID: 15341318] - Drew R Ekman, W Walter Lorenz, Alan E Przybyla, N Lee Wolfe, Jeffrey F D Dean. SAGE analysis of transcriptome responses in Arabidopsis roots exposed to 2,4,6-trinitrotoluene.
Plant physiology.
2003 Nov; 133(3):1397-406. doi:
10.1104/pp.103.028019. [PMID: 14551330] - Pradnya Kanekar, Premlata Dautpure, Seema Sarnaik. Biodegradation of nitro-explosives.
Indian journal of experimental biology.
2003 Sep; 41(9):991-1001. doi:
NULL. [PMID: 15242292] - Chuanyue Wang, Delina Y Lyon, Joseph B Hughes, George N Bennett. Role of hydroxylamine intermediates in the phytotransformation of 2,4,6-trinitrotoluene by Myriophyllum aquaticum.
Environmental science & technology.
2003 Aug; 37(16):3595-600. doi:
10.1021/es030010a. [PMID: 12953871] - Mikko Puhakka, Jarkko Magga, Seppo Hietakorpi, Ilkka Penttilä, Paavo Uusimaa, Juha Risteli, Keijo Peuhkurinen. Interleukin-6 and tumor necrosis factor alpha in relation to myocardial infarct size and collagen formation.
Journal of cardiac failure.
2003 Aug; 9(4):325-32. doi:
10.1054/jcaf.2003.38. [PMID: 13680554] - S Letzel, Th Göen, M Bader, J Angerer, T Kraus. Exposure to nitroaromatic explosives and health effects during disposal of military waste.
Occupational and environmental medicine.
2003 Jul; 60(7):483-8. doi:
10.1136/oem.60.7.483. [PMID: 12819281] - Ellen R Goldman, Andrew Hayhurst, Brian M Lingerfelt, Brent L Iverson, George Georgiou, George P Anderson. 2,4,6-Trinitrotoluene detection using recombinant antibodies.
Journal of environmental monitoring : JEM.
2003 Jun; 5(3):380-3. doi:
10.1039/b302012f. [PMID: 12833979] - Heike Knicker. Incorporation of (15)N-TNT transformation products into humifying plant organic matter as revealed by one- and two-dimensional solid state NMR spectroscopy.
The Science of the total environment.
2003 Jun; 308(1-3):211-20. doi:
10.1016/s0048-9697(02)00610-1. [PMID: 12738214] - D R Hitchcock, S C McCutcheon, M C Smith. Using rotifer population demographic parameters to assess impacts of the degradation products from trinitrotoluene phytoremediation.
Ecotoxicology and environmental safety.
2003 Jun; 55(2):143-51. doi:
10.1016/s0147-6513(03)00007-1. [PMID: 12742360] - Teresa B Fitzpatrick, Nikolaus Amrhein, Peter Macheroux. Characterization of YqjM, an Old Yellow Enzyme homolog from Bacillus subtilis involved in the oxidative stress response.
The Journal of biological chemistry.
2003 May; 278(22):19891-7. doi:
10.1074/jbc.m211778200. [PMID: 12660247] - Kijune Sung, C L Munster, R Rhykerd, M C Drew, M Yavuz Corapcioglu. The use of vegetation to remediate soil freshly contaminated by recalcitrant contaminants.
Water research.
2003 May; 37(10):2408-18. doi:
10.1016/s0043-1354(03)00029-0. [PMID: 12727252] - P Y Robidoux, G Bardai, L Paquet, G Ampleman, S Thiboutot, J Hawari, G I Sunahara. Phytotoxicity of 2,4,6-trinitrotoluene (TNT) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) in spiked artificial and natural forest soils.
Archives of environmental contamination and toxicology.
2003 Feb; 44(2):198-209. doi:
10.1007/s00244-002-2018-1. [PMID: 12520392] - Tobias Frische. Ecotoxicological evaluation of in situ bioremediation of soils contaminated by the explosive 2,4,6-trinitrotoluene (TNT).
Environmental pollution (Barking, Essex : 1987).
2003; 121(1):103-13. doi:
10.1016/s0269-7491(02)00196-3. [PMID: 12475067] - A Halasz, C Groom, E Zhou, L Paquet, C Beaulieu, S Deschamps, A Corriveau, S Thiboutot, G Ampleman, C Dubois, Jalal Hawari. Detection of explosives and their degradation products in soil environments.
Journal of chromatography. A.
2002 Jul; 963(1-2):411-8. doi:
10.1016/s0021-9673(02)00553-8. [PMID: 12187997] - Stephen W Maloney, Neal R Adrian, Robert F Hickey, Robert L Heine. Anaerobic treatment of pinkwater in a fluidized bed reactor containing GAC.
Journal of hazardous materials.
2002 May; 92(1):77-88. doi:
10.1016/s0304-3894(01)00375-2. [PMID: 11976000] - Shino Homma-Takeda, Yusuke Hiraku, Yasuhiro Ohkuma, Shinji Oikawa, Mariko Murata, Kazuhiko Ogawa, Taeko Iwamuro, Song Li, Gui Fan Sun, Yoshito Kumagai, Nobuhiro Shimojo, Shosuke Kawanishi. 2,4,6-trinitrotoluene-induced reproductive toxicity via oxidative DNA damage by its metabolite.
Free radical research.
2002 May; 36(5):555-66. doi:
10.1080/10715760290025933. [PMID: 12150543] - Zhongde Zhu, Zhilan Li, Fatai Mi, Suqin Lian, Pengcheng Dong, Yuhua Wu, Xiaohua Sun. [Study on the relationship between the opacity of lens and the levels of 2, 6-dinitro-4-amino-toluene (DNAT) in the urine of workers exposed to trinitrotoluene(TNT)].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2002 Feb; 20(1):42-3. doi:
NULL. [PMID: 14694615] - Tobias Frische. Screening for soil toxicity and mutagenicity using luminescent bacteria--a case study of the explosive 2,4,6-trinitrotoluene (TNT).
Ecotoxicology and environmental safety.
2002 Feb; 51(2):133-44. doi:
10.1006/eesa.2001.2124. [PMID: 11886187] - Robert M Gogal, Mark S Johnson, Calvert T Larsen, Mary R Prater, Robert B Duncan, Daniel L Ward, Steven D Holladay. Influence of dietary 2,4,6-trinitrotoluene exposure in the northern bobwhite (Colinus virginianus).
Environmental toxicology and chemistry.
2002 Jan; 21(1):81-6. doi:
NULL. [PMID: 11804065]
