Exact Mass: 153.0789746
Exact Mass Matches: 153.0789746
Found 500 metabolites which its exact mass value is equals to given mass value 153.0789746,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Dopamine
Dopamine is a member of the catecholamine family of neurotransmitters in the brain and is a precursor to epinephrine (adrenaline) and norepinephrine (noradrenaline). Dopamine is synthesized in the body (mainly by nervous tissue and adrenal glands) first by the hydration of the amino acid tyrosine to DOPA by tyrosine hydroxylase and then by the decarboxylation of DOPA by aromatic-L-amino-acid decarboxylase. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (dopamine receptors) mediates its action, which plays a major role in reward-motivated behaviour. Dopamine has many other functions outside the brain. In blood vessels, dopamine inhibits norepinephrine release and acts as a vasodilator (at normal concentrations); in the kidneys, it increases sodium excretion and urine output; in the pancreas, it reduces insulin production; in the digestive system, it reduces gastrointestinal motility and protects intestinal mucosa; and in the immune system, it reduces the activity of lymphocytes. Parkinsons disease, a degenerative condition causing tremor and motor impairment, is caused by a loss of dopamine-secreting neurons in an area of the midbrain called the substantia nigra. There is evidence that schizophrenia involves altered levels of dopamine activity, and most antipsychotic drugs used to treat this are dopamine antagonists, which reduce dopamine activity. Attention deficit hyperactivity disorder, bipolar disorder, and addiction are also characterized by defects in dopamine production or metabolism. It has been suggested that animals derived their dopamine-synthesizing machinery from bacteria via horizontal gene transfer that may have occurred relatively late in evolutionary time. This is perhaps a result of the symbiotic incorporation of bacteria into eukaryotic cells that gave rise to mitochondria. Dopamine is elevated in the urine of people who consume bananas. When present in sufficiently high levels, dopamine can be a neurotoxin and a metabotoxin. A neurotoxin is a compound that disrupts or attacks neural tissue. A metabotoxin is an endogenously produced metabolite that causes adverse health effects at chronically high levels. Chronically high levels of dopamine are associated with neuroblastoma, Costello syndrome, leukemia, phaeochromocytoma, aromatic L-amino acid decarboxylase deficiency, and Menkes disease (MNK). High levels of dopamine can lead to hyperactivity, insomnia, agitation and anxiety, depression, delusions, excessive salivation, nausea, and digestive problems. A study has shown that urinary dopamine is produced by Bacillus and Serratia (PMID: 24621061) Occurs in several higher plants, such as banana (Musa sapientum). As a member of the catecholamine family, dopamine is a precursor to norepinephrine (noradrenaline) and then epinephrine (adrenaline) in the biosynthetic pathways for these neurotransmitters. Dopamine is elevated in the urine of people who consume bananas. Dopamine is found in many foods, some of which are garden onion, purslane, garden tomato, and swiss chard. Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 80\% of the catecholamine content in the brain. It is an amine synthesized by removing a carboxyl group from a molecule of its precursor chemical, L-DOPA, which is synthesized in the brain and kidneys. Dopamine is also synthesized in plants and most animals. In the brain, dopamine functions as a neurotransmitter—a chemical released by neurons (nerve cells) to send signals to other nerve cells. Neurotransmitters are synthesized in specific regions of the brain, but affect many regions systemically. The brain includes several distinct dopamine pathways, one of which plays a major role in the motivational component of reward-motivated behavior. The anticipation of most types of rewards increases the level of dopamine in the brain,[4] and many addictive drugs increase dopamine release or block its reuptake into neurons following release.[5] Other brain dopamine pathways are involved in motor control and in controlling the release of various hormones. These pathways and cell groups form a dopamine system which is neuromodulatory.[5] In popular culture and media, dopamine is often portrayed as the main chemical of pleasure, but the current opinion in pharmacology is that dopamine instead confers motivational salience;[6][7][8] in other words, dopamine signals the perceived motivational prominence (i.e., the desirability or aversiveness) of an outcome, which in turn propels the organism's behavior toward or away from achieving that outcome.[8][9] Outside the central nervous system, dopamine functions primarily as a local paracrine messenger. In blood vessels, it inhibits norepinephrine release and acts as a vasodilator; in the kidneys, it increases sodium excretion and urine output; in the pancreas, it reduces insulin production; in the digestive system, it reduces gastrointestinal motility and protects intestinal mucosa; and in the immune system, it reduces the activity of lymphocytes. With the exception of the blood vessels, dopamine in each of these peripheral systems is synthesized locally and exerts its effects near the cells that release it. Several important diseases of the nervous system are associated with dysfunctions of the dopamine system, and some of the key medications used to treat them work by altering the effects of dopamine. Parkinson's disease, a degenerative condition causing tremor and motor impairment, is caused by a loss of dopamine-secreting neurons in an area of the midbrain called the substantia nigra. Its metabolic precursor L-DOPA can be manufactured; Levodopa, a pure form of L-DOPA, is the most widely used treatment for Parkinson's. There is evidence that schizophrenia involves altered levels of dopamine activity, and most antipsychotic drugs used to treat this are dopamine antagonists which reduce dopamine activity.[10] Similar dopamine antagonist drugs are also some of the most effective anti-nausea agents. Restless legs syndrome and attention deficit hyperactivity disorder (ADHD) are associated with decreased dopamine activity.[11] Dopaminergic stimulants can be addictive in high doses, but some are used at lower doses to treat ADHD. Dopamine itself is available as a manufactured medication for intravenous injection. It is useful in the treatment of severe heart failure or cardiogenic shock.[12] In newborn babies it may be used for hypotension and septic shock.[13] Dopamine is synthesized in a restricted set of cell types, mainly neurons and cells in the medulla of the adrenal glands.[22] The primary and minor metabolic pathways respectively are: Primary: L-Phenylalanine → L-Tyrosine → L-DOPA → Dopamine[19][20] Minor: L-Phenylalanine → L-Tyrosine → p-Tyramine → Dopamine[19][20][21] Minor: L-Phenylalanine → m-Tyrosine → m-Tyramine → Dopamine[21][23][24] The direct precursor of dopamine, L-DOPA, can be synthesized indirectly from the essential amino acid phenylalanine or directly from the non-essential amino acid tyrosine.[25] These amino acids are found in nearly every protein and so are readily available in food, with tyrosine being the most common. Although dopamine is also found in many types of food, it is incapable of crossing the blood–brain barrier that surrounds and protects the brain.[26] It must therefore be synthesized inside the brain to perform its neuronal activity.[26] L-Phenylalanine is converted into L-tyrosine by the enzyme phenylalanine hydroxylase, with molecular oxygen (O2) and tetrahydrobiopterin as cofactors. L-Tyrosine is converted into L-DOPA by the enzyme tyrosine hydroxylase, with tetrahydrobiopterin, O2, and iron (Fe2+) as cofactors.[25] L-DOPA is converted into dopamine by the enzyme aromatic L-amino acid decarboxylase (also known as DOPA decarboxylase), with pyridoxal phosphate as the cofactor.[25] Dopamine itself is used as precursor in the synthesis of the neurotransmitters norepinephrine and epinephrine.[25] Dopamine is converted into norepinephrine by the enzyme dopamine β-hydroxylase, with O2 and L-ascorbic acid as cofactors.[25] Norepinephrine is converted into epinephrine by the enzyme phenylethanolamine N-methyltransferase with S-adenosyl-L-methionine as the cofactor.[25] Some of the cofactors also require their own synthesis.[25] Deficiency in any required amino acid or cofactor can impair the synthesis of dopamine, norepinephrine, and epinephrine.[25] Degradation Dopamine is broken down into inactive metabolites by a set of enzymes—monoamine oxidase (MAO), catechol-O-methyl transferase (COMT), and aldehyde dehydrogenase (ALDH), acting in sequence.[27] Both isoforms of monoamine oxidase, MAO-A and MAO-B, effectively metabolize dopamine.[25] Different breakdown pathways exist but the main end-product is homovanillic acid (HVA), which has no known biological activity.[27] From the bloodstream, homovanillic acid is filtered out by the kidneys and then excreted in the urine.[27] The two primary metabolic routes that convert dopamine into HVA are:[28] Dopamine → DOPAL → DOPAC → HVA – catalyzed by MAO, ALDH, and COMT respectively Dopamine → 3-Methoxytyramine → HVA – catalyzed by COMT and MAO+ALDH respectively In clinical research on schizophrenia, measurements of homovanillic acid in plasma have been used to estimate levels of dopamine activity in the brain. A difficulty in this approach however, is separating the high level of plasma homovanillic acid contributed by the metabolism of norepinephrine.[29][30] Although dopamine is normally broken down by an oxidoreductase enzyme, it is also susceptible to oxidation by direct reaction with oxygen, yielding quinones plus various free radicals as products.[31] The rate of oxidation can be increased by the presence of ferric iron or other factors. Quinones and free radicals produced by autoxidation of dopamine can poison cells, and there is evidence that this mechanism may contribute to the cell loss that occurs in Parkinson's disease and other conditions.[32]
N-Acetylhistamine
N-Acetylhistamine is a 4-(beta-Acetylaminoethyl)imidazole that is an intermediate in Histidine metabolism. It is generated from Histamine via the enzyme Transferases (EC 2.3.1.-). Histamine is an amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. Isolated from leaves of Spinacia oleracea (spinach). N-Acetylhistamine is found in green vegetables and spinach. KEIO_ID A093 N-Acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions. N-Acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
psi-Pelletierine
psi-Pelletierine is found in fruits. psi-Pelletierine is found in bark of pomegranate (Punica granatum Found in bark of pomegranate (Punica granatum) KEIO_ID P054
P-Hydroxyphenylethanolamine
Alkaloid from leaves of tabasco pepper (Capsicum frutescens), nutgrass (Cyperus rotundus) and leaves or fruit of Citrus subspecies Occurs in many animal tissues; found in high concs. in octopus p-Octopamine is an amine in traces quantities in plasma and cerebrospinal fluid in humans with septic encephalopathy (PMID 15932098). D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
FAPy-adenine
Fapy-adenine is an oxidized DNA base. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases (PMID 15116424). Oxidative stress damage to DNA bases may contribute to neuronal loss in Alzheimers disease (AD). Increased levels were observed in parietal, temporal, occipital, and frontal lobe, superior temporal gyrus, and hippocampus areas of the brain in patients with AD. (PMID 9109533). Fapy-adenine is an oxidized DNA base. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases. (PMID 15116424) FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases[1][2][3].
2,4-Diamino-6-hydroxylaminotoluene
A member of the class of aminotoluenes that is 2,4-diaminotoluene bearing an additional hydroxylamino substituent at position 6.
Vanillylamine
Vanillylamine is prepared by reacting vanillin with hydroxylamine or the salts thereof in the presence of an organic salt, which may optionally be produced in situ, wherein the reaction is carried out in an inorganic or organic acid as diluent, and subsequently hydrogenating the resulting vanillyloxime with hydrogen in the presence of a suitable catalyst and an organic and/or inorganic acid.It inhibits microsomal enzyme function; RN given refers to parent cpd. Vanillylamine is a component of capsaicin.In Pseudomonas fluorescens B56 under growing conditions, the cells metabolized vanillylamine to vanillin, and vanillin to vanillic acid and a small amount of vanillyl alcohol. Under non-growing conditions, the cells produced vanillin, vanillic acid and protocatechuic acid from vanillylamine, and vanillic acid supplied to the medium was converted to protocatechuic acid. It is thus suggested that vanillylamine is metabolized to vanillic acid through vanillin by Pseudomonas fluorescens B56 in a rich medium, however, in a starving medium, the bacterial strain further metabolizes vanillic acid to protocatechuic acid. The vanillylamine metabolic activity was slowly induced by the substrate. Vanillylamine is prepared by reacting vanillin with hydroxylamine or the salts thereof in the presence of an organic salt, which may optionally be produced in situ, wherein the reaction is carried out in an inorganic or organic acid as diluent, and subsequently hydrogenating the resulting vanillyloxime with hydrogen in the presence of a suitable catalyst and an organic and/or inorganic acid.It inhibits microsomal enzyme function; RN given refers to parent cpd Vanillylamine is an aralkylamino compound. It is functionally related to a vanillyl alcohol. It is a conjugate base of a vanillylamine(1+). Vanillylamine is a natural product found in Capsicum annuum with data available. Vanillylamine is a derivative of vanillin is synthesized through a transaminase reaction in the phenylpropanoid pathway of capsaicinoid synthesis[1].
4-Nitro-o-phenylenediamine
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents D009676 - Noxae > D002273 - Carcinogens
2-Methyl-4-pentyloxazole
2-Methyl-4-pentyloxazole is found in potato. 2-Methyl-4-pentyloxazole is a constituent of French fries. Constituent of French fries. 2-Methyl-4-pentyloxazole is found in potato.
4-Methyl-2-pentyloxazole
4-Methyl-2-pentyloxazole is found in potato. 4-Methyl-2-pentyloxazole is a volatile constituent of French fried potato. Volatile constituent of French fried potato. 4-Methyl-2-pentyloxazole is found in potato.
5-Butyl-2-ethyloxazole
5-Butyl-2-ethyloxazole is a volatile constituent of roasted peanuts. Volatile constituent of roasted peanuts
2-Ethyl-4-methyl-5-propyloxazole
2-Ethyl-4-methyl-5-propyloxazole is found in potato. 2-Ethyl-4-methyl-5-propyloxazole is a constituent of French fries. Constituent of French fries. 2-Ethyl-4-methyl-5-propyloxazole is found in potato.
4-Ethyl-2-methyl-5-propyloxazole
4-Ethyl-2-methyl-5-propyloxazole is found in cocoa and cocoa products. 4-Ethyl-2-methyl-5-propyloxazole is a volatile constituent of French fried potato and cocoa butter. Volatile constituent of French fried potato and cocoa butter. 4-Ethyl-2-methyl-5-propyloxazole is found in cocoa and cocoa products and potato.
5-Ethyl-4-methyl-2-(1-methylethyl)oxazole
5-Ethyl-4-methyl-2-(1-methylethyl)oxazole is found in potato. 5-Ethyl-4-methyl-2-(1-methylethyl)oxazole is a volatile constituent of French fried potato. Volatile constituent of French fried potato. 5-Ethyl-4-methyl-2-(1-methylethyl)oxazole is found in potato.
2-Butyl-4,5-dimethyloxazole
2-Butyl-4,5-dimethyloxazole is found in potato. 2-Butyl-4,5-dimethyloxazole is a constituent of French fries. Constituent of French fries. 2-Butyl-4,5-dimethyloxazole is found in potato.
5-Ethyl-2-methyl-4-propyloxazole
5-Ethyl-2-methyl-4-propyloxazole is found in nuts. 5-Ethyl-2-methyl-4-propyloxazole is a constituent of roasted peanuts. Constituent of roasted peanuts. 5-Ethyl-2-methyl-4-propyloxazole is found in nuts.
4-Ethyl-5-methyl-2-(1-methylethyl)oxazole
4-Ethyl-5-methyl-2-(1-methylethyl)oxazole is found in cocoa and cocoa products. 4-Ethyl-5-methyl-2-(1-methylethyl)oxazole is a constituent of yeast extracts, cocoa butter or beans and roasted peanut volatiles. Constituent of yeast extracts, cocoa butter or beans and roasted peanut volatiles. 4-Ethyl-5-methyl-2-(1-methylethyl)oxazole is found in cocoa and cocoa products and nuts.
4-Butyl-2,5-dimethyloxazole
Constituent of roast beef, cocoa butter and French fried potato aroma. 4-Butyl-2,5-dimethyloxazole is found in cocoa and cocoa products, animal foods, and potato. 4-Butyl-2,5-dimethyloxazole is found in animal foods. 4-Butyl-2,5-dimethyloxazole is a constituent of roast beef, cocoa butter and French fried potato aroma.
2-Isobutyl-4,5-dimethyloxazole
2-Isobutyl-4,5-dimethyloxazole is found in potato. 2-Isobutyl-4,5-dimethyloxazole is a constituent of French fried potato volatiles. Constituent of French fried potato volatiles. 2-Isobutyl-4,5-dimethyloxazole is found in potato.
4-Ethyl-5-methyl-2-propyloxazole
Not reported in nature. Not reported in nature
5-Butyl-2,4-dimethyloxazole
Not reported in nature. Not reported in nature
2-Fluoroadenine
2-Fluoroadenine is a toxic purine bases. 2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for researching anticancer[1].
2-Fluoroamphetamine
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
4-Fluoroamphetamine
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
Bucrilate
D001697 - Biomedical and Dental Materials > D014014 - Tissue Adhesives C78275 - Agent Affecting Blood or Body Fluid
Enbucrilate
D001697 - Biomedical and Dental Materials > D014014 - Tissue Adhesives
Norfenefrine
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
(2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone
(2e)-4-hydroxy-5-methyl-2-propylidene-3(2h)-furanone is soluble (in water) and a very weakly acidic compound (based on its pKa). (2e)-4-hydroxy-5-methyl-2-propylidene-3(2h)-furanone can be found in a number of food items such as lovage, black raspberry, mustard spinach, and sunflower, which makes (2e)-4-hydroxy-5-methyl-2-propylidene-3(2h)-furanone a potential biomarker for the consumption of these food products.
Achyin
Betaine Hydrochloride is the hydrochloride form of betaine, a crystalline alkaloid occurring in sugar beets and other plants. Betaine, acting as a transmethylating metabolic intermediate, is the oxidation product of choline. Betaine hydrochloride is used as a gastric acidifier supplement. A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)
Norfenefrine
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
4-Fluoroamphetamine
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
Monofluoroamphetamine
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
Gabapentin-lactam
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 7 INTERNAL_ID 7; CONFIDENCE Reference Standard (Level 1) CONFIDENCE standard compound; INTERNAL_ID 2687 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 1003
1-(6-methyl-2,3,4,5-tetrahydro-pyridin-2-yl)-propan-2-one
2-cyanonaphthalene|2-naphthalenecarbonitrile|2-naphthonitrile|alpha-amino(naphthalen-2-yl)acetic acid|naphthalen-2-carbonitrile|naphthalene-2-carbonitrile|napthalene-2-carbonitrile
1-Methoxymethyl-1,2-dehydro-8alpha-pyrrolizidin|1-methoxymethyl-1,2-dehydro-8alpha-pyrrolizidine
N-(2,3,3a,4,5,6,7,7a-octahydroinden-1-ylidene)hydroxylamine
1-cyanonaphthalene|1-naphthalenecarbonitrile|1-naphthaline-carbonitrile|1-naphthonitrile|cyanonaphthalene|naphthalene-1-carbonitrile|naphthalenyl-1-carbonitrile
DL-Norphenylephrine
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.053 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.052 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.051
Dopamine
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group. D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; VYFYYTLLBUKUHU_STSL_0097_Dopamine_2000fmol_180430_S2_LC02_MS02_90; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
FAPy-adenine
FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases[1][2][3].
N-Acetylhistamine
A member of the class of acetamides that is acetamide comprising histamine having an acetyl group attached to the side-chain amino function. N-Acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions. N-Acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
Methyl 3-aminopyrazine-2-carboxylic acid
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; INCSQLZZXBPATR-UHFFFAOYSA-N_STSL_0205_Methyl 3-aminopyrazine-2-carboxylate_0125fmol_180831_S2_L02M02_25; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
octopamine
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents Octopamine, also known as beta,4-dihydroxyphenethylamine, is an endogenous biogenic amine that is closely related to norepinephrine, and has effects on the adrenergic and dopaminergic systems. Octopamine is found in lemon, sweet orange, and pepper (c. frutescens).
Pyrrole-2-carboxaldehyde, 3-methoxy-4,5-dimethyl- (8CI)
2H-1,2,3-Triazole-4-carboxylicacid,2-ethenyl-,methylester(9CI)
1H-Pyrrole-2-carboxamide,1-amino-3,4-dimethyl-(9CI)
2-[(2-methylpropan-2-yl)oxy]ethanamine,hydrochloride
Hydracarbazine
C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic
1H-Imidazole-4-carboximidamide,5-amino-N-ethyl-(9CI)
4,5,6,7-tetrahydro-1,2-benzisoxazol-3-ylmethanol(SALTDATA: FREE)
Thieno[3,2-c]pyridine, 4,5,6,7-tetrahydro-6-methyl- (9CI)
Ethanolomine Thioglycholate
Monoethanolamine thioglycolate. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=126-97-6 (retrieved 2024-08-05) (CAS RN: 126-97-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
2,5,6,7,8,9-HEXAHYDRO-3H-[1,2,4]TRIAZOLO[4,3-A]AZEPIN-3-ONE
1,3-CYCLOPENTANEDICARBOXYLICACID,1-AMINO-,(1R,3S)-
4-[CARBOXY-(4-TRIFLUOROMETHYL-PHENYL)-METHYL]-PIPERAZINE-1-CARBOXYLICACIDTERT-BUTYLESTERHYDROCHLORIDE
Pyrazinecarboxamide, 3,4-dihydro-6-methyl-3-oxo- (9CI)
1H-Imidazo[1,2-b]pyrazole-7-carboxylicacid,2,3-dihydro-(9CI)
2-amino-4-methyl-6-oxo-3H-pyrimidine-5-carbaldehyde
2-(fluoromethyl)piperidine hydrochloride
C6H13ClFN (153.07205000000002)
4-PYRIMIDINECARBOXYLIC ACID, 2-AMINO-, METHYL ESTER
1H-Pyrrole-3-carboxylicacid,2,4-dimethyl-,methylester(9CI)
4-Fluoromethylpiperidine hydrochloride
C6H13ClFN (153.07205000000002)
2-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-3(2H)-ONE
4,5,6,7-TETRAHYDRO-2,1,3-BENZOXADIAZOL-4-ONE OXIME
1H-Imidazole-4-carboximidamide,1-methyl-5-(methylamino)-
(3R,4S)-1-AZABICYCLO[2.2.1]HEPTANE-3-CARBOXYLICACID
1-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-N-methylmethanamine
(3R,4R)-4-(hydroxymethyl)pyrrolidin-1-ium-3-ol chloride
Thieno[3,2-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- (8CI,9CI)
2-Pyrimidinecarboxylicacid, 4-amino-, methyl ester
Pyrazinecarboxylic acid,3-amino-6-methyl- (7CI,8CI,9CI)
1H-1,2,3-Triazolo[4,5-d]pyrimidine,4,7-dihydro-7-methoxy-(9CI)
6-Oxo-1,6-dihydropyridine-3-carboxylic acid hydrazide
Pyrrolo[1,2-d][1,2,4]triazin-1(2H)-one, 6,7,8,8a-tetrahydro-4-methyl-, (S)- (9CI)
1H-1,2,3-Triazole-4-carboxaldehyde, 1-(1,1-dimethylethyl)- (9CI)
2-(5-cyclopropyl-[1,3,4]oxadiazol-2-yl)-ethylamine
2-Oxo-1,2-dihydropyridine-4-carboxylic acid hydrazide
1-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-N-methylmethanamine
1-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-N-methylmethanamine
2-(TRIMETHYLSILYL)ETHANAMINE HYDROCHLORIDE
C5H16ClNSi (153.07404860000003)
(E)-1-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)-N-hydroxymethanimine
Betaine Hydrochloride
A - Alimentary tract and metabolism > A09 - Digestives, incl. enzymes > A09A - Digestives, incl. enzymes > A09AB - Acid preparations D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D008082 - Lipotropic Agents D009676 - Noxae > D000963 - Antimetabolites D005765 - Gastrointestinal Agents
Vanillylamine
Vanillylamine is a derivative of vanillin is synthesized through a transaminase reaction in the phenylpropanoid pathway of capsaicinoid synthesis[1].
bucrilate
D001697 - Biomedical and Dental Materials > D014014 - Tissue Adhesives C78275 - Agent Affecting Blood or Body Fluid
Dopamin
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents
4-Deoxypyridoxine
A pyridine ring substituted with methyl groups at positions 2 and 4, a hydroxyl at position 3, and a hydroxymethyl group at position 5. D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D000893 - Anti-Inflammatory Agents
(2S)-4-(prop-1-en-1-yl)-2,3-dihydro-1H-pyrrole-2-carboxylate
(2S)-4-[(E)-prop-1-enyl]-2,3-dihydro-1H-pyrrole-2-carboxylic acid
3-amino-6,7,8,8a-tetrahydroimidazo[1,5-a]pyridin-1(5H)-one
4-Nitro-o-phenylenediamine
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents D009676 - Noxae > D002273 - Carcinogens
4-[(1R)-2-amino-1-hydroxyethyl]phenol
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
TCMDC-124283
2-Fluoroadenine is a toxic purine bases. 2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for researching anticancer[1].