6-Hydrazinonicotinic acid (BioDeep_00000174934)
human metabolite blood metabolite
代谢物信息卡片
6-hydrazinylpyridine-3-carboxylic acid
化学式: C6H7N3O2 (153.0538)
中文名称: 6-肼基烟酸
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: C1=CC(=NC=C1C(=O)O)NN
InChI: InChI=1S/C6H7N3O2/c7-9-5-2-1-4(3-8-5)6(10)11/h1-3H,7H2,(H,8,9)(H,10,11)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Rodrigo Teodoro, Bluma Linkowski Faintuch, Eutimio Gustavo Fernández Núñez, Rodrigo Guimarães Queiróz. Neurotensin(8-13) analogue: radiolabeling and biological evaluation using different chelators.
Nuclear medicine and biology.
2011 Jan; 38(1):113-20. doi:
10.1016/j.nucmedbio.2010.06.011. [PMID: 21220134] - Meser M Ali, Branislava Janic, Abbas Babajani-Feremi, Nadimpalli R S Varma, A S M Iskander, John Anagli, Ali S Arbab. Changes in vascular permeability and expression of different angiogenic factors following anti-angiogenic treatment in rat glioma.
PloS one.
2010 Jan; 5(1):e8727. doi:
10.1371/journal.pone.0008727. [PMID: 20090952] - Martin Latterich, Jacques Corbeil. Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method.
Proteome science.
2008 Nov; 6(?):31. doi:
10.1186/1477-5956-6-31. [PMID: 18983648] - Mojtaba Salouti, Hossein Rajabi, Mohammad Hossein Babaei, Mohammad Javad Rasaee. Breast tumor targeting with (99m)Tc-HYNIC-PR81 complex as a new biologic radiopharmaceutical.
Nuclear medicine and biology.
2008 Oct; 35(7):763-8. doi:
10.1016/j.nucmedbio.2008.07.002. [PMID: 18848661] - Ming Zhao, Zhixin Li, Scott Bugenhagen. 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2008 Aug; 49(8):1345-52. doi:
10.2967/jnumed.107.048603. [PMID: 18632826] - Jerzy Kosowicz, Renata Mikołajczak, Rafał Czepczyński, Katarzyna Ziemnicka, Maria Gryczyńska, Jerzy Sowiński. Two peptide receptor ligands (99m)Tc-EDDA/HYNIC-Tyr(3)-octreotide and (99m)Tc-EDDA/HYNIC-(D)Glu-octagastrin for scintigraphy of medullary thyroid carcinoma.
Cancer biotherapy & radiopharmaceuticals.
2007 Oct; 22(5):613-28. doi:
10.1089/cbr.2006.368. [PMID: 17979564] - Ekaterina Dadachova, Tiffany Moadel, Andrew D Schweitzer, Ruth A Bryan, Tong Zhang, Lisa Mints, Ekaterina Revskaya, Xianchuan Huang, Geraldina Ortiz, Jerome S Nosanchuk, Joshua D Nosanchuk, Arturo Casadevall. Radiolabeled melanin-binding peptides are safe and effective in treatment of human pigmented melanoma in a mouse model of disease.
Cancer biotherapy & radiopharmaceuticals.
2006 Apr; 21(2):117-29. doi:
10.1089/cbr.2006.21.117. [PMID: 16706632] - Daniel Storch, Martin Béhé, Martin A Walter, Jianhua Chen, Pia Powell, Renata Mikolajczak, Helmut R Mäcke. Evaluation of [99mTc/EDDA/HYNIC0]octreotide derivatives compared with [111In-DOTA0,Tyr3, Thr8]octreotide and [111In-DTPA0]octreotide: does tumor or pancreas uptake correlate with the rate of internalization?.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2005 Sep; 46(9):1561-9. doi:
. [PMID: 16157541] - Mohammad Hossein Babaei, Ylva Almqvist, Anna Orlova, Mohammad Shafii, Kalevi Kairemo, Vladimir Tolmachev. [99mTc] HYNIC-hEGF, a potential agent for imaging of EGF receptors in vivo: preparation and pre-clinical evaluation.
Oncology reports.
2005 Jun; 13(6):1169-75. doi:
10.3892/or.13.6.1169. [PMID: 15870939] - Eun-Mi Kim, Hwan-Jeong Jeong, Young-Jun Heo, Hyung-Bae Moon, Hee-Seung Bom, Chang-Guhn Kim. Intratumoral injection of 188Re labeled cationic polyethylenimine conjugates: a preliminary report.
Journal of Korean medical science.
2004 Oct; 19(5):647-51. doi:
10.3346/jkms.2004.19.5.647. [PMID: 15483337] - Kyoko Takagi, Tomoya Uehara, Emi Kaneko, Morio Nakayama, Mitsuru Koizumi, Keigo Endo, Yasushi Arano. 99mTc-labeled mannosyl-neoglycoalbumin for sentinel lymph node identification.
Nuclear medicine and biology.
2004 Oct; 31(7):893-900. doi:
10.1016/j.nucmedbio.2004.04.008. [PMID: 15464391] - E von Guggenberg, M Behe, T M Behr, M Saurer, T Seppi, C Decristoforo. 99mTc-labeling and in vitro and in vivo evaluation of HYNIC- and (Nalpha-His)acetic acid-modified [D-Glu1]-minigastrin.
Bioconjugate chemistry.
2004 Jul; 15(4):864-71. doi:
10.1021/bc0300807. [PMID: 15264875] - Laura Meléndez-Alafort, Flor de María Ramírez, Guillermina Ferro-Flores, Consuelo Arteaga de Murphy, Martha Pedraza-López, Donald J Hnatowich. Lys and Arg in UBI: a specific site for a stable Tc-99m complex?.
Nuclear medicine and biology.
2003 Aug; 30(6):605-15. doi:
10.1016/s0969-8051(03)00055-6. [PMID: 12900286] - William E P Greenland, Kevin Howland, Judith Hardy, Ignac Fogelman, Philip J Blower. Solid-phase synthesis of peptide radiopharmaceuticals using Fmoc-N-epsilon-(hynic-Boc)-lysine, a technetium-binding amino acid: application to Tc-99m-labeled salmon calcitonin.
Journal of medicinal chemistry.
2003 Apr; 46(9):1751-7. doi:
10.1021/jm030761n. [PMID: 12699393] - Zi-Fen Su, Jiang He, Mary Rusckowski, Donald J Hnatowich. In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands.
Nuclear medicine and biology.
2003 Feb; 30(2):141-9. doi:
10.1016/s0969-8051(02)00390-6. [PMID: 12623113] - Masahiro Ono, Yasushi Arano, Takahiro Mukai, Tsuneo Saga, Yasushi Fujioka, Kazuma Ogawa, Hidekazu Kawashima, Junji Konishi, Hideo Saji. Control of radioactivity pharmacokinetics of 99mTc-HYNIC-labeled polypeptides derivatized with ternary ligand complexes.
Bioconjugate chemistry.
2002 May; 13(3):491-501. doi:
10.1021/bc010043k. [PMID: 12009938] - Zi-Fen Su, Guozheng Liu, Suresh Gupta, Zhihong Zhu, Mary Rusckowski, Donald J Hnatowich. In vitro and in vivo evaluation of a Technetium-99m-labeled cyclic RGD peptide as a specific marker of alpha(V)beta(3) integrin for tumor imaging.
Bioconjugate chemistry.
2002 May; 13(3):561-70. doi:
10.1021/bc0155566. [PMID: 12009947]
