Exact Mass: 132.047

Exact Mass Matches: 132.047

Found 198 metabolites which its exact mass value is equals to given mass value 132.047, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

3-ureidopropionate

3-[(Aminocarbonyl)amino]propanoic acid

C4H8N2O3 (132.0535)


Ureidopropionic acid, also known as 3-ureidopropanoate or N-carbamoyl-beta-alanine, belongs to the class of organic compounds known as ureas. Ureas are compounds containing two amine groups joined by a carbonyl (C=O) functional group. Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically, it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed into beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency (PMID: 11675655). Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil. Ureidopropionic acid has been detected, but not quantified in, several different foods, such as gram beans, broccoli, climbing beans, oriental wheat, and mandarin orange (clementine, tangerine). This could make ureidopropionic acid a potential biomarker for the consumption of these foods. N-Carbamoyl-β-alanine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=462-88-4 (retrieved 2024-07-01) (CAS RN: 462-88-4). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil.

   

Asparagine

(2S)-2-Amino-3-carbamoylpropanoic acid

C4H8N2O3 (132.0535)


Asparagine (Asn) or L-asparagine is an alpha-amino acid. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Amino acids are organic compounds that contain amino (–NH2) and carboxyl (–COOH) functional groups, along with a side chain (R group) specific to each amino acid. L-asparagine is one of 20 proteinogenic amino acids, i.e., the amino acids used in the biosynthesis of proteins. Asparagine is found in all organisms ranging from bacteria to plants to animals. In humans, asparagine is not an essential amino acid, which means that it can be synthesized from central metabolic pathway intermediates in humans and is not required in the diet. The precursor to asparagine is oxaloacetate. Oxaloacetate is converted to aspartate using a transaminase enzyme. This enzyme transfers the amino group from glutamate to oxaloacetate producing alpha-ketoglutarate and aspartate. The enzyme asparagine synthetase produces asparagine, AMP, glutamate, and pyrophosphate from aspartate, glutamine, and ATP. In the asparagine synthetase reaction, ATP is used to activate aspartate, forming beta-aspartyl-AMP. Glutamine donates an ammonium group which reacts with beta-aspartyl-AMP to form asparagine and free AMP. Since the asparagine side chain can make efficient hydrogen bond interactions with the peptide backbone, asparagines are often found near the beginning and end of alpha-helices, and in turn motifs in beta sheets. Its role can be thought as "capping" the hydrogen bond interactions which would otherwise need to be satisfied by the polypeptide backbone. Asparagine also provides key sites for N-linked glycosylation, a modification of the protein chain that is characterized by the addition of carbohydrate chains. A reaction between asparagine and reducing sugars or reactive carbonyls produces acrylamide (acrylic amide) in food when heated to sufficient temperature (i.e. baking). These occur primarily in baked goods such as French fries, potato chips, and roasted coffee. Asparagine was first isolated in 1806 from asparagus juice --hence its name. Asparagine was the first amino acid to be isolated. The smell observed in the urine of some individuals after the consumption of asparagus is attributed to a byproduct of the metabolic breakdown of asparagine, asparagine-amino-succinic-acid monoamide. However, some scientists disagree and implicate other substances in the smell, especially methanethiol. [Spectral] L-Asparagine (exact mass = 132.05349) and L-Aspartate (exact mass = 133.03751) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions. One of the nonessential amino acids. Dietary supplement, nutrient. Widely distributed in the plant kingdom. Isolated from asparagus, beetroot, peas, beans, etc. (-)-Asparagine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=70-47-3 (retrieved 2024-07-15) (CAS RN: 70-47-3). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

   

Glycylglycine

Monohydrochloride, glycylglycine

C4H8N2O3 (132.0535)


The simplest peptide, made of two glycine molecules; used in the synthesis of more complicated peptides. Glycine is a simple, nonessential amino acid, although experimental animals show reduced growth on low-glycine diets. The average adult ingests 3 to 5 grams of glycine daily. Glycine is involved in the bodys production of DNA, phospholipids and collagen, and in release of energy. Glycine levels are effectively measured in plasma in both normal patients and those with inborn errors of glycine metabolism. (http://www.dcnutrition.com/AminoAcids/) Nonketotic hyperglycinaemia (OMIM 606899) is an autosomal recessive condition caused by deficient enzyme activity of the glycine cleavage enzyme system (EC 2.1.1.10). The glycine cleavage enzyme system comprises four proteins: P-, T-, H- and L-proteins (EC 1.4.4.2, EC 2.1.2.10 and EC 1.8.1.4 for P-, T- and L-proteins). Mutations have been described in the GLDC (OMIM 238300), AMT (OMIM 238310), and GCSH (OMIM 238330) genes encoding the P-, T-, and H-proteins respectively. The glycine cleavage system catalyses the oxidative conversion of glycine into carbon dioxide and ammonia, with the remaining one-carbon unit transferred to folate as methylenetetrahydrofolate. It is the main catabolic pathway for glycine and it also contributes to one-carbon metabolism. Patients with a deficiency of this enzyme system have increased glycine in plasma, urine and cerebrospinal fluid (CSF) with an increased CSF: plasma glycine ratio. (PMID 16151895) [HMDB] The simplest peptide, made of two glycine molecules; used in the synthesis of more complicated peptides. Glycine is a simple, nonessential amino acid, although experimental animals show reduced growth on low-glycine diets. The average adult ingests 3 to 5 grams of glycine daily. Glycine is involved in the bodys production of DNA, phospholipids and collagen, and in release of energy. Glycine levels are effectively measured in plasma in both normal patients and those with inborn errors of glycine metabolism. (http://www.dcnutrition.com/AminoAcids/) Nonketotic hyperglycinaemia (OMIM 606899) is an autosomal recessive condition caused by deficient enzyme activity of the glycine cleavage enzyme system (EC 2.1.1.10). The glycine cleavage enzyme system comprises four proteins: P-, T-, H- and L-proteins (EC 1.4.4.2, EC 2.1.2.10 and EC 1.8.1.4 for P-, T- and L-proteins). Mutations have been described in the GLDC (OMIM 238300), AMT (OMIM 238310), and GCSH (OMIM 238330) genes encoding the P-, T-, and H-proteins respectively. The glycine cleavage system catalyses the oxidative conversion of glycine into carbon dioxide and ammonia, with the remaining one-carbon unit transferred to folate as methylenetetrahydrofolate. It is the main catabolic pathway for glycine and it also contributes to one-carbon metabolism. Patients with a deficiency of this enzyme system have increased glycine in plasma, urine and cerebrospinal fluid (CSF) with an increased CSF: plasma glycine ratio. (PMID 16151895). Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID G037 Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor.

   

Glutaric acid

1,3-Propanedicarboxylic acid

C5H8O4 (132.0423)


Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan. Glutaric acid may cause irritation to the skin and eyes. When present in sufficiently high levels, glutaric acid can act as an acidogen and a metabotoxin. An acidogen is an acidic compound that induces acidosis, which has multiple adverse effects on many organ systems. A metabotoxin is an endogenously produced metabolite that causes adverse health effects at chronically high levels. Chronically high levels of glutaric acid are associated with at least three inborn errors of metabolism, including glutaric aciduria type I, malonyl-CoA decarboxylase deficiency, and glutaric aciduria type III. Glutaric aciduria type I (glutaric acidemia type I, glutaryl-CoA dehydrogenase deficiency, GA1, or GAT1) is an inherited disorder in which the body is unable to completely break down the amino acids lysine, hydroxylysine, and tryptophan due to a deficiency of mitochondrial glutaryl-CoA dehydrogenase (EC 1.3.99.7, GCDH). Excessive levels of their intermediate breakdown products (e.g. glutaric acid, glutaryl-CoA, 3-hydroxyglutaric acid, glutaconic acid) can accumulate and cause damage to the brain (and also other organs). Babies with glutaric acidemia type I are often born with unusually large heads (macrocephaly). Macrocephaly is amongst the earliest signs of GA1. GA1 also causes secondary carnitine deficiency because glutaric acid, like other organic acids, is detoxified by carnitine. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis. Acidosis typically occurs when arterial pH falls below 7.35. In infants with acidosis, the initial symptoms include poor feeding, vomiting, loss of appetite, weak muscle tone (hypotonia), and lack of energy (lethargy). These can progress to heart, liver, and kidney abnormalities, seizures, coma, and possibly death. These are also the characteristic symptoms of untreated glutaric aciduria. Many affected children with organic acidemias experience intellectual disability or delayed development. In adults, acidosis or acidemia is characterized by headaches, confusion, feeling tired, tremors, sleepiness, and seizures. Treatment of glutaric aciduria is mainly based on the restriction of lysine intake, supplementation of carnitine, and an intensification of therapy during intercurrent illnesses. The major principle of dietary treatment is to reduce the production of glutaric acid and 3-hydroxyglutaric acid by restriction of natural protein, in general, and of lysine, in particular (PMID: 17465389, 15505398). Glutaric acid has also been found in Escherichia (PMID: 30143200). Isolated from basidiomycete fungi and fruits of Prunus cerasus (CCD). Glutaric acid is found in many foods, some of which are red beetroot, common beet, soy bean, and tamarind. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3]. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3].

   

2-Acetolactate

2-hydroxy-2-methyl-3-oxobutanoic acid

C5H8O4 (132.0423)


2-Acetolactate is involved in the butanoate metabolism and pantothenate and CoA biosynthesis pathways. In the butanoate metabolism pathway, 2-Acetolactate is created from 2-(alpha-Hydroxyethyl)thiamine diphosphate by acetolactate synthase [EC:2.2.1.6]. 2-Acetolactate is then converted to (R)-Acetoin by acetolactate decarboxylase [EC:4.1.1.5]. In the pantothenate and CoA pathway, 2-Acetolactate is irreversibly created from pyruvate by acetolactate synthase [EC:2.2.1.6]. 2-Acetolactate is then irreversibly converted to 2,3-Dihydroxy-3-methylbutanoate by ketol-acid reductoisomerase [EC:1.1.1.86]. 2-Acetolactate is involved in the butanoate metabolism and pantothenate and CoA biosynthesis pathways.

   

N-Carbamoylsarcosine

[Carbamoyl(methyl)amino]acetic acid

C4H8N2O3 (132.0535)


N-Carbamoylsarcosine is an intermediate in arginine and proline metabolism. It is also involved in a metabolic pathway for the degradation of creatinine. In this pathway, creatinine is not hydrolyzed back to creatine. Instead, it is deaminated to N-methylhydantoin, releasing an amonia molecule, by the action of creatinine deaminase (also known as creatinine iminohydrolase). N-methylhydantoin is then hydrolyzed to N-carbamoylsarcosine, by the action of N-methylhydantoin amidohydrolase, at the expense of one ATP molecule. N-carbamoylsarcosine is deaminated further to sarcosine by N-carbamoylsarcosine amidohydrolase, releasing a second ammonia molecule. In the last step of this pathway, sarcosine is hydrolyzed to glycine and formaldehyde, by either sarcosine dehydrogenase or sarcosine oxidase. [HMDB] N-Carbamoylsarcosine is an intermediate in arginine and proline metabolism. It is also involved in a metabolic pathway for the degradation of creatinine. In this pathway, creatinine is not hydrolyzed back to creatine. Instead, it is deaminated to N-methylhydantoin, releasing an amonia molecule, by the action of creatinine deaminase (also known as creatinine iminohydrolase). N-methylhydantoin is then hydrolyzed to N-carbamoylsarcosine, by the action of N-methylhydantoin amidohydrolase, at the expense of one ATP molecule. N-carbamoylsarcosine is deaminated further to sarcosine by N-carbamoylsarcosine amidohydrolase, releasing a second ammonia molecule. In the last step of this pathway, sarcosine is hydrolyzed to glycine and formaldehyde, by either sarcosine dehydrogenase or sarcosine oxidase.

   

Deoxyribonolactone

(4S,5R)-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

C5H8O4 (132.0423)


   

4-Hydroxy-2-oxovalerate

4-Hydroxy-2-oxopentanoic acid

C5H8O4 (132.0423)


   

2-(hydroxymethyl)-4-oxobutanoic acid

2-(hydroxymethyl)-4-oxobutanoic acid

C5H8O4 (132.0423)


   

3-Hydroxy-3-methyl-2-oxobutanoic acid

3-Hydroxy-3-methyl-2-oxobutanoic acid

C5H8O4 (132.0423)


   

Pteridine

1,3,5,8-Tetraazanaphthalene

C6H4N4 (132.0436)


   

4,5-dihydroxypentane-2,3-dione

(4S)-4,5-Dihydroxy-2,3-pentanedione

C5H8O4 (132.0423)


   

METHYLAZOXYMETHANOL ACETATE

METHYLAZOXYMETHANOL ACETATE

C4H8N2O3 (132.0535)


D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors D009676 - Noxae > D009498 - Neurotoxins

   

N-NITROSO-N-METHYLURETHANE

N-methyl-N-oxoethoxycarbohydrazide

C4H8N2O3 (132.0535)


D009676 - Noxae > D000477 - Alkylating Agents

   

(S)-2-Acetolactate

(2S)-2-hydroxy-2-methyl-3-oxobutanoic acid

C5H8O4 (132.0423)


(S)-2-Acetolactate is an intermediate in the biosynthesis of valine, leucine and isoleucine (KEGG ID C06010 ). It is the sixth to last step in the synthesis of protein and is converted from 2-hydroxy-3-methyl-2-oxobutanoate via the enzyme acetolactate synthase [EC:2.2.1.6]. It is then converted to 3-hydroxy-3-methyl-2-oxobutanoate via the enzyme ketol-acid reductoisomerase [EC:1.1.1.86]. [HMDB]. (S)-2-Acetolactate is found in many foods, some of which are chickpea, japanese persimmon, fruits, and star fruit. (S)-2-Acetolactate is an intermediate in the biosynthesis of valine, leucine and isoleucine (KEGG ID C06010 ). It is the sixth to last step in the synthesis of protein and is converted from 2-hydroxy-3-methyl-2-oxobutanoate via the enzyme acetolactate synthase [EC:2.2.1.6]. It is then converted to 3-hydroxy-3-methyl-2-oxobutanoate via the enzyme ketol-acid reductoisomerase [EC:1.1.1.86]. D018377 - Neurotransmitter Agents > D018847 - Opioid Peptides D018377 - Neurotransmitter Agents > D004399 - Dynorphins

   

D-Asparagine

(2R)-2-Amino-3-carbamoylpropanoic acid

C4H8N2O3 (132.0535)


D-Asparagine, also known as DSG, belongs to the class of organic compounds known as asparagine and derivatives. D-Asparagome is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. Asparagine and derivatives are compounds containing asparagine or a derivative thereof resulting from reaction of asparagine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. It is codified by the codons AAU and AAC. It is biosynthesized from Aspartic acid and Ammonia by asparagine synthetase.

   

DL-Asparagine

2-amino-3-(C-hydroxycarbonimidoyl)propanoic acid

C4H8N2O3 (132.0535)


DL-Asparagine is a racemic melange of the Aparagine L and D-enantiomers. DL-Asparagine has been used in growth-media for bacteria-growth[1]. DL-Asparagine is a racemic melange of the Aparagine L and D-enantiomers. DL-Asparagine has been used in growth-media for bacteria-growth[1].

   

Ethylmalonate

1,1-Propanedicarboxylic acid

C5H8O4 (132.0423)


Ethylmalonic acid, also known as alpha-carboxybutyric acid or ethylmalonate, is a member of the class of compounds known as branched fatty acids. Branched fatty acids are fatty acids containing one or more branched chains. Ethylmalonic acid is soluble (in water) and a moderately acidic compound (based on its pKa). Ethylmalonic acid can be synthesized from malonic acid, and can be synthesized into (S)-ethylmalonyl-CoA and (R)-ethylmalonyl-CoA. Ethylmalonic acid can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid is found to be associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency. Ethylmalonic acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Chronically high levels of ethylmalonic acid are associated with at least two inborn errors of metabolism, including short-chain acyl-CoA dehydrogenase deficiency (SCAD deficiency) and ethylmalonic encephalopathy. Ethylmalonic acid is identified in the urine of patients with short-chain acyl-CoA dehydrogenase deficiency, which is a fatty acid metabolism disorder. When present at sufficiently high levels, ethylmalonic acid can act as an acidogen and a metabotoxin. An acidogen is an acidic compound that induces acidosis, which has multiple adverse effects on many organ systems. A metabotoxin is an endogenously produced metabolite that causes adverse health effects at chronically high levels. Ethylmalonic acid is an organic acid. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis. Acidosis typically occurs when arterial pH falls below 7.35. In infants with acidosis, the initial symptoms include poor feeding, vomiting, loss of appetite, weak muscle tone (hypotonia), and lack of energy (lethargy). These can progress to heart abnormalities, kidney abnormalities, liver damage, seizures, coma, and possibly death. These are also the characteristic symptoms of the untreated IEMs mentioned above. Many affected children with organic acidemias experience intellectual disability or delayed development. In adults, acidosis or acidemia is characterized by headaches, confusion, feeling tired, tremors, sleepiness, and seizures. Ethylmalonic acid is identified in the urine of patients with short-chain acyl-coenzyme A dehydrogenase deficiency, which is a fatty acid metabolism disorder. [HMDB] Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.

   

Methylsuccinate

(-)-(S)-alpha-Methylsuccinic acid

C5H8O4 (132.0423)


Methylsuccinic acid (CAS: 498-21-5) is a normal metabolite found in human fluids. Increased urinary levels of methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy (OMIM: 602473), a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay, hyperlactic acidemia, recurrent petechiae, orthostatic acrocyanosis, and chronic diarrhea (PMID:12382164). The underlying biochemical defect involves isoleucine catabolism (PMID:9667231). Methylsuccinic acid levels were found to have decreased in the urine of animals under D-serine-induced nephrotoxicity (D-serine causes selective necrosis of the proximal straight tubules in the rat kidney) (PMID:15596249). Moreover, methylsuccinic acid is found to be associated with ethylmalonic encephalopathy, isovaleric acidemia, and medium-chain acyl-CoA dehydrogenase deficiency, which are also inborn errors of metabolism. Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy (OMIM 602473 ), a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay, hyperlactic acidemia, recurrent petechiae, orthostatic acrocyanosis, and chronic diarrhea. (PMID 12382164) T he underlying biochemical defect involves isoleucine catabolism. (PMID 9667231) 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.

   

2-Deoxy-L-ribono-1,4-lactone

(4S,5R)-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

C5H8O4 (132.0423)


2-Deoxy-L-ribono-1,4-lactone is found in herbs and spices. 2-Deoxy-L-ribono-1,4-lactone is a constituent of the fruit of Foeniculum vulgare (fennel). Constituent of the fruit of Foeniculum vulgare (fennel). 2-Deoxy-L-ribono-1,4-lactone is found in herbs and spices.

   

2-Hydroxy-4-oxopentanoic acid

PENTANOIC ACID, 2-HYDROXY-4-OXO-

C5H8O4 (132.0423)


2-Hydroxy-4-oxopentanoic acid is found in alcoholic beverages. 2-Hydroxy-4-oxopentanoic acid is formed in beer wort fermentation Alitretinoin (9-cis-retinoic acid) is a naturally-occurring endogenous retinoid indicated for topical treatment of cutaneous lesions in patients with AIDS-related Kaposis sarcoma. Alitretinoin inhibits the growth of Kaposis sarcoma (KS) cells in vitro. Retinoic acid is the oxidized form of Vitamin A. It functions in determining position along embryonic anterior/posterior axis in chordates. It acts through Hox genes, which ultimately control anterior/posterior patterning in early developmental stages. Retinoic acid acts by binding to heterodimers of the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), which then bind to retinoic acid response elements (RAREs) in the regulatory regions of direct targets (including Hox genes), thereby activating gene transcription. Retinoic acid receptors mediate transcription of different sets of genes of cell differentiation, thus it also depends on the target cells. 2-Hydroxy-4-oxopentanoic acid is one of the target genes is the gene of the retinoic acid receptor itself which occurs during positive regulation. Control of retinoic acid levels is maintained by a suite of proteins. Retinoic acid is the oxidized form of Vitamin A. It functions in determining position along embryonic anterior/posterior axis in chordates. It acts through Hox genes, which ultimately controls anterior/posterior patterning in early developmental stages (PMID: 17495912). It is an important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth and embryonic development. 2-Hydroxy-4-oxopentanoic acid is an excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute). Formed in beer wort fermentation

   

2-C-Methyl-1,4-erythrono-D-lactone

2-C-Methyl-1,4-erythrono-D-lactone

C5H8O4 (132.0423)


Constituent of Trifolium incarnatum (crimson clover) and Phaseolus vulgaris (kidney bean). 2-C-Methyl-1,4-erythrono-D-lactone is found in many foods, some of which are tea, yellow wax bean, green bean, and pulses. (2xi,3xi)-4,5-Dihydro-3,4-dihydroxy-3-methyl-2(3H)-furanone is found in pulses. (2xi,3xi)-4,5-Dihydro-3,4-dihydroxy-3-methyl-2(3H)-furanone is isolated from chickpea Cicer arietinum.

   

Monoethyl malonic acid

Malonic acid monoethyl ester

C5H8O4 (132.0423)


Monoethyl malonic acid is an organic acid identified in the urine in a healthy pediatric population. (PMID 14708889) [HMDB] Monoethyl malonic acid is an organic acid identified in the urine in a healthy pediatric population. (PMID 14708889). 3-Ethoxy-3-oxopropanoic acid is an endogenous metabolite. 3-Ethoxy-3-oxopropanoic acid promotes plant growth[1].

   

Dimethylmalonic acid

Hydrogen 2,2-dimethylmalonate

C5H8O4 (132.0423)


Dimethylmalonic acid is a dicarboxylic acid that is malonic acid in which both methylene hydrogens have been replaced by methyl groups. It has a role as a fatty acid synthesis inhibitor. Dimethylmalonic acid, also known as 2,2-dimethylmalonate or propanedioate, belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. Dimethylmalonic acid is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. Dimethylmalonic acid is a short-chain dicarboxylic acid occasionally found in human serum (PMID 7762817). Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath[1].

   

N-carbamoylalanine

2-(carbamoylamino)propanoic acid

C4H8N2O3 (132.0535)


   

(Methyl-ONN-azoxy)methyl acetate

[(acetyloxy)methyl](methyl-oxo-λ⁵-azanylidene)amine

C4H8N2O3 (132.0535)


   

Monomethyl succinate

Butanedioic acid monomethyl ester

C5H8O4 (132.0423)


   

Methyl(acetoxymethyl)nitrosamine

[methyl(nitroso)amino]methyl acetate

C4H8N2O3 (132.0535)


D009676 - Noxae > D002273 - Carcinogens

   

Dimethyl malonate

1,3-dimethyl propanedioate

C5H8O4 (132.0423)


Dimethyl malonate, also known as dimethyl malonic acid, belongs to dicarboxylic acids and derivatives class of compounds. Those are organic compounds containing exactly two carboxylic acid groups. Dimethyl malonate is soluble (in water) and a very weakly acidic compound (based on its pKa). Dimethyl malonate is a fruity tasting compound found in pineapple, which makes dimethyl malonate a potential biomarker for the consumption of this food product. Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1]. Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1].

   

Pyrimido[5,4-d]pyrimidine

pyrimido[5,4-d][1,3]diazine

C6H4N4 (132.0436)


   

Formyl 3-hydroxybutanoate

Formyl 3-hydroxybutanoic acid

C5H8O4 (132.0423)


   

2-Deoxy-D-ribono-1,4-lactone

(4S,5R)-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

C5H8O4 (132.0423)


   

SCHEMBL7305255

SCHEMBL7305255

C5H8O4 (132.0423)


   

3,4-dihydroxy-2-methylidenebutanoic acid

3,4-dihydroxy-2-methylidenebutanoic acid

C5H8O4 (132.0423)


   

SCHEMBL21350260

SCHEMBL21350260

C5H8O4 (132.0423)


   

methyl N-(methylcarbamoyl)carbamate

methyl N-(methylcarbamoyl)carbamate

C4H8N2O3 (132.0535)


   

Isoasparagine

Isoasparagine

C4H8N2O3 (132.0535)


   

2-Acetoxypropanoic acid

2-Acetoxypropanoic acid

C5H8O4 (132.0423)


   

3-hydroxy-5-hydroxymethyl-dihydro-furan-2-one

3-hydroxy-5-hydroxymethyl-dihydro-furan-2-one

C5H8O4 (132.0423)


   

4-Methoxy-4-oxobutanoic acid

4-Methoxy-4-oxobutanoic acid

C5H8O4 (132.0423)


   

3,4-Dihydroxy-5-methyl-dihydrofuran-2-one

3,4-Dihydroxy-5-methyl-dihydrofuran-2-one

C5H8O4 (132.0423)


   

Ethyl allophanate

Ethyl allophanate

C4H8N2O3 (132.0535)


   

SCHEMBL9144805

SCHEMBL9144805

C5H8O4 (132.0423)


   

Dimethyl malonate

Dimethyl malonate

C5H8O4 (132.0423)


Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1]. Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1].

   

5-hydroxy-4-oxopentanoic acid

5-hydroxy-4-oxopentanoic acid

C5H8O4 (132.0423)


   

5-hydroxy-2-oxopentanoic acid

5-hydroxy-2-oxopentanoic acid

C5H8O4 (132.0423)


   

Dimethyl_malonate

PROPANEDIOIC ACID,DIMETHYL ESTER (MALONIC ACID,DIMETHYL ESTER)

C5H8O4 (132.0423)


Dimethyl malonate is a natural product found in Astragalus mongholicus, Myrtus communis, and Astragalus membranaceus with data available. Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1]. Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1].

   

Methylsuccinic acid

(2S)-2-methylbutanedioic acid

C5H8O4 (132.0423)


Acquisition and generation of the data is financially supported in part by CREST/JST. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.

   

L-Asparagine

L-Asparagine

C4H8N2O3 (132.0535)


An optically active form of asparagine having L-configuration. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

   

Ureidopropionic acid

N-Carbamoyl-beta-alanine

C4H8N2O3 (132.0535)


A beta-alanine derivative that is propionic acid bearing a ureido group at position 3. Ureidopropionic acid, also known as 3-ureidopropionate or N-carbamoyl-beta-alanine, is a member of the class of compounds known as ureas. Ureas are compounds containing two amine groups joined by a carbonyl (C=O) functional group. Ureidopropionic acid is soluble (in water) and a weakly acidic compound (based on its pKa). Ureidopropionic acid can be found in a number of food items such as brussel sprouts, cascade huckleberry, common sage, and atlantic herring, which makes ureidopropionic acid a potential biomarker for the consumption of these food products. Ureidopropionic acid can be found primarily in blood, cerebrospinal fluid (CSF), feces, and urine. In humans, ureidopropionic acid is involved in a couple of metabolic pathways, which include beta-alanine metabolism and pyrimidine metabolism. Ureidopropionic acid is also involved in several metabolic disorders, some of which include MNGIE (mitochondrial neurogastrointestinal encephalopathy), dihydropyrimidinase deficiency, UMP synthase deficiency (orotic aciduria), and gaba-transaminase deficiency. Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil.

   

ETHYLMALONIC ACID

2-ethyl-propanedioic acid

C5H8O4 (132.0423)


A dicarboxylic acid obtained by substitution of one of the methylene hydrogens of malonic acid by an ethyl group. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.

   

Gly-gly

H-Gly-Gly-OH

C4H8N2O3 (132.0535)


Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor.

   

GLUTARIC ACID

GLUTARIC ACID

C5H8O4 (132.0423)


An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3]. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3].

   

Glycyl-glycine

Glycyl-glycine

C4H8N2O3 (132.0535)


Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor.

   

Monoethyl malonic acid

3-Ethoxy-3-oxopropanoic acid

C5H8O4 (132.0423)


3-Ethoxy-3-oxopropanoic acid is an endogenous metabolite. 3-Ethoxy-3-oxopropanoic acid promotes plant growth[1].

   

DIMETHYLMALONIC ACID

2,2-Dimethylmalonic acid

C5H8O4 (132.0423)


Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath[1].

   

3-Ureidopropionic acid

3-Ureidopropionic acid

C4H8N2O3 (132.0535)


   

L-Asparagine

L-Asparagine

C4H8N2O3 (132.0535)


An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 2-amino-2-oxoethyl group. COVID info from PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

   

Glutaric acid (Not validated)

Glutaric acid (Not validated)

C5H8O4 (132.0423)


Annotation level-2

   

N-carbamoyl-beta-alaninate

N-carbamoyl-beta-alaninate

C4H8N2O3 (132.0535)


   

3-Ureidopropionate

3-Ureidopropionate

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; LC-tDDA; CE10

3-Ureidopropionic acid; LC-tDDA; CE10

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; LC-tDDA; CE20

3-Ureidopropionic acid; LC-tDDA; CE20

C4H8N2O3 (132.0535)


   

Asparagine; LC-tDDA; CE10

Asparagine; LC-tDDA; CE10

C4H8N2O3 (132.0535)


   

Asparagine; LC-tDDA; CE20

Asparagine; LC-tDDA; CE20

C4H8N2O3 (132.0535)


   

Asparagine; LC-tDDA; CE30

Asparagine; LC-tDDA; CE30

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; AIF; CE0; CorrDec

3-Ureidopropionic acid; AIF; CE0; CorrDec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; AIF; CE10; CorrDec

3-Ureidopropionic acid; AIF; CE10; CorrDec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; AIF; CE30; CorrDec

3-Ureidopropionic acid; AIF; CE30; CorrDec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; AIF; CE0; MS2Dec

3-Ureidopropionic acid; AIF; CE0; MS2Dec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; AIF; CE10; MS2Dec

3-Ureidopropionic acid; AIF; CE10; MS2Dec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; AIF; CE30; MS2Dec

3-Ureidopropionic acid; AIF; CE30; MS2Dec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE0; CorrDec

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE0; CorrDec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE10; CorrDec

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE10; CorrDec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE30; CorrDec

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE30; CorrDec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE0; MS2Dec

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE0; MS2Dec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE10; MS2Dec

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE10; MS2Dec

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE30; MS2Dec

3-Ureidopropionic acid [M+H-H2O]+; AIF; CE30; MS2Dec

C4H8N2O3 (132.0535)


   

Asparagine; AIF; CE0; CorrDec

Asparagine; AIF; CE0; CorrDec

C4H8N2O3 (132.0535)


   

Asparagine; AIF; CE10; CorrDec

Asparagine; AIF; CE10; CorrDec

C4H8N2O3 (132.0535)


   

Asparagine; AIF; CE30; CorrDec

Asparagine; AIF; CE30; CorrDec

C4H8N2O3 (132.0535)


   

Asparagine; AIF; CE0; MS2Dec

Asparagine; AIF; CE0; MS2Dec

C4H8N2O3 (132.0535)


   

Asparagine; AIF; CE10; MS2Dec

Asparagine; AIF; CE10; MS2Dec

C4H8N2O3 (132.0535)


   

Asparagine; AIF; CE30; MS2Dec

Asparagine; AIF; CE30; MS2Dec

C4H8N2O3 (132.0535)


   

Asparagine; LC-tDDA; CE40

Asparagine; LC-tDDA; CE40

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; LC-tDDA; CE30

3-Ureidopropionic acid; LC-tDDA; CE30

C4H8N2O3 (132.0535)


   

3-Ureidopropionic acid; LC-tDDA; CE40

3-Ureidopropionic acid; LC-tDDA; CE40

C4H8N2O3 (132.0535)


   

Glutarate

GLUTARIC ACID

C5H8O4 (132.0423)


Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3]. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3].

   

Ethylmalonate

ETHYLMALONIC ACID

C5H8O4 (132.0423)


Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.

   

Ureidopropionate

Ureidopropionic acid

C4H8N2O3 (132.0535)


Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil.

   

3,5-Dimethoxyphenol

3,5-Dimethoxyphenol

C5H8O4 (132.0423)


   
   

Pyrotartarate

(S)-2-HYDROXY-2-METHYLSUCCINIC ACID

C5H8O4 (132.0423)


2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.

   

Dimethylmalonate

2,2-dimethylpropanedioic acid

C5H8O4 (132.0423)


Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath[1].

   

3,4-dihydroxy-3-methyloxolan-2-one

3,4-dihydroxy-3-methyloxolan-2-one

C5H8O4 (132.0423)


   

L-erythro-Form

4,5-dihydro-4-Hydroxy-5-(hydroxymethyl)-2(3H)-furanone

C5H8O4 (132.0423)


   

Acetolactic acid

PENTANOIC ACID, 2-HYDROXY-4-OXO-

C5H8O4 (132.0423)


   

FA 5:1;O2

(4S)-4-hydroxy-2-ketovaleric acid;(4S)-4-hydroxy-2-oxovaleric acid;(S)-4-hydroxy-2-ketopentanoic acid

C5H8O4 (132.0423)


D018377 - Neurotransmitter Agents > D018847 - Opioid Peptides D018377 - Neurotransmitter Agents > D004399 - Dynorphins 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.

   

Thiourea, N-(aminoiminomethyl)-N-methyl- (9CI)

Thiourea, N-(aminoiminomethyl)-N-methyl- (9CI)

C3H8N4S (132.047)


   

2-hydroxybutanediamide

2-hydroxybutanediamide

C4H8N2O3 (132.0535)


   

Pyrimido[4,5-d]pyrimidine (8CI,9CI)

Pyrimido[4,5-d]pyrimidine (8CI,9CI)

C6H4N4 (132.0436)


   

Pyrimido[4,5-d]pyridazine (7CI,8CI,9CI)

Pyrimido[4,5-d]pyridazine (7CI,8CI,9CI)

C6H4N4 (132.0436)


   

(4S)-4-(Methoxymethyl)-1,3-dioxolan-2-one

(4S)-4-(Methoxymethyl)-1,3-dioxolan-2-one

C5H8O4 (132.0423)


   

3-(hydrazinecarbonyl)propanoic acid

3-(hydrazinecarbonyl)propanoic acid

C4H8N2O3 (132.0535)


   

3-methylazetidine-3-carbonitrile hydrochloride

3-methylazetidine-3-carbonitrile hydrochloride

C5H9ClN2 (132.0454)


   

1-Methylimidazole-4,5-dicarbonitrile

1-Methylimidazole-4,5-dicarbonitrile

C6H4N4 (132.0436)


   

(R)-PYRROLIDINE-2-CARBONITRILE HYDROCHLORIDE

(R)-PYRROLIDINE-2-CARBONITRILE HYDROCHLORIDE

C5H9ClN2 (132.0454)


   

4-NITRO MORPHOLINE

4-NITRO MORPHOLINE

C4H8N2O3 (132.0535)


   

(R)-(+)-Methylsuccinic Acid

(R)-(+)-Methylsuccinic Acid

C5H8O4 (132.0423)


   

Methylene diacetate

Methylene diacetate

C5H8O4 (132.0423)


   

ethyl 2-hydrazinyl-2-oxoacetate

ethyl 2-hydrazinyl-2-oxoacetate

C4H8N2O3 (132.0535)


   

Tricyanoaminopropene

Tricyanoaminopropene

C6H4N4 (132.0436)


   

1-Aminocyclobutanecarbonitrile hydrochloride

1-Aminocyclobutanecarbonitrile hydrochloride

C5H9ClN2 (132.0454)


   

Pyrimido[5,4-d]pyrimidine

Pyrimido[5,4-d]pyrimidine (7CI,8CI,9CI)

C6H4N4 (132.0436)


   

(S)-Pyrrolidine-2-carbonitrile hydrochloride

(S)-Pyrrolidine-2-carbonitrile hydrochloride

C5H9ClN2 (132.0454)


   

2-(Acetyloxy)-propanoic acid

2-(Acetyloxy)-propanoic acid

C5H8O4 (132.0423)


   

2-Pyrrolidinecarbonitrile hydrochloride

2-Pyrrolidinecarbonitrile hydrochloride

C5H9ClN2 (132.0454)


   

(3R)-pyrrolidine-3-carbonitrile,hydrochloride

(3R)-pyrrolidine-3-carbonitrile,hydrochloride

C5H9ClN2 (132.0454)


   

(3S)-pyrrolidine-3-carbonitrile,hydrochloride

(3S)-pyrrolidine-3-carbonitrile,hydrochloride

C5H9ClN2 (132.0454)


   

1,4-Dioxane-2-carboxylic acid

1,4-Dioxane-2-carboxylic acid

C5H8O4 (132.0423)


   

Pyrido[2,3-e][1,2,4]triazine

Pyrido[2,3-e][1,2,4]triazine

C6H4N4 (132.0436)


   

2-methoxymalonamide

2-methoxymalonamide

C4H8N2O3 (132.0535)


   

Ethyl (2E)-amino(hydroxyimino)acetate

Ethyl (2E)-amino(hydroxyimino)acetate

C4H8N2O3 (132.0535)


   

3-Methoxy-2-methyl-3-oxopropanoic acid

3-Methoxy-2-methyl-3-oxopropanoic acid

C5H8O4 (132.0423)


   

((1E)-1-METHOXY-2-NITROVINYL)METHYLAMINE

((1E)-1-METHOXY-2-NITROVINYL)METHYLAMINE

C4H8N2O3 (132.0535)


   

(+/-)-1-PHENYL-3-AZABICYCLO[3.1.0]HEXANE

(+/-)-1-PHENYL-3-AZABICYCLO[3.1.0]HEXANE

C5H8O4 (132.0423)


   

1-(aminomethyl)cyclopropanecarbonitrile hcl

1-(aminomethyl)cyclopropanecarbonitrile hcl

C5H9ClN2 (132.0454)


   

L-threo-Pentonic acid, 2-deoxy-, .gamma.-lactone

L-threo-Pentonic acid, 2-deoxy-, .gamma.-lactone

C5H8O4 (132.0423)


   

Pyrimido[5,4-c]pyridazine (7CI,8CI,9CI)

Pyrimido[5,4-c]pyridazine (7CI,8CI,9CI)

C6H4N4 (132.0436)


   
   

(s)-(-)-2-acetoxypropionic acid

(s)-(-)-2-acetoxypropionic acid

C5H8O4 (132.0423)


   

2-[(2-azanylacetyl)amino]acetic acid

2-[(2-azanylacetyl)amino]acetic acid

C4H8N2O3 (132.0535)


   

1-methoxy-1-methylamino-2-nitroethylene

1-methoxy-1-methylamino-2-nitroethylene

C4H8N2O3 (132.0535)


   

4,5-Dimethyl-1H-imidazolhydrochlorid

4,5-Dimethyl-1H-imidazolhydrochlorid

C5H9ClN2 (132.0454)


   

d-aspartic acid α-amide hydrochloride

d-aspartic acid α-amide hydrochloride

C4H8N2O3 (132.0535)


   

2,5-Dihydroxy-4-pentanolide

2,5-Dihydroxy-4-pentanolide

C5H8O4 (132.0423)


   

C-(1H-Pyrrol-3-yl)-methylamine hydrochloride

C-(1H-Pyrrol-3-yl)-methylamine hydrochloride

C5H9ClN2 (132.0454)


   

(R)-(+)-3-HYDROXY-3-PHENYLPROPIONICACID

(R)-(+)-3-HYDROXY-3-PHENYLPROPIONICACID

C5H8O4 (132.0423)


   

Pyrimido[4,5-c]pyridazine (7CI,8CI,9CI)

Pyrimido[4,5-c]pyridazine (7CI,8CI,9CI)

C6H4N4 (132.0436)


   

3-(Difluoromethyl)-5-methyl-1H-pyrazole

3-(Difluoromethyl)-5-methyl-1H-pyrazole

C5H6F2N2 (132.0499)


   

(1H-Pyrrol-2-yl)methanamine hydrochloride

(1H-Pyrrol-2-yl)methanamine hydrochloride

C5H9ClN2 (132.0454)


   

2(1H)-Pyridinone,5-methyl-, sodium salt (1:1)

2(1H)-Pyridinone,5-methyl-, sodium salt (1:1)

C6H7NNaO+ (132.0425)


   

Glycine Anhydride

Glycine Anhydride

C4H8N2O3 (132.0535)


   

(S)-4,5-dihydroxypentane-2,3-dione

(4S)-4,5-Dihydroxy-2,3-pentanedione

C5H8O4 (132.0423)


Pentane substituted at the 2- and 3-positions by oxo groups, at the 4- and 5-positions by hydroxy groups and with S stereoconfiguration at C-4.

   

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

C5H8O4 (132.0423)


   

Pentanoic acid, 5-hydroxy-4-oxo-

Pentanoic acid, 5-hydroxy-4-oxo-

C5H8O4 (132.0423)


   

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

C5H8O4 (132.0423)


   

DL-Asparagine

DL-Asparagine

C4H8N2O3 (132.0535)


   

l-Isoasparagine

l-Isoasparagine

C4H8N2O3 (132.0535)


   

3-(N-Nitroso-N-methylamino)propionic acid

3-(N-Nitroso-N-methylamino)propionic acid

C4H8N2O3 (132.0535)


   

(2S)-2-(carbamoylamino)propanoic acid

(2S)-2-(carbamoylamino)propanoic acid

C4H8N2O3 (132.0535)


   

2-(2H-imidazol-2-ylidene)-2H-imidazole

2-(2H-imidazol-2-ylidene)-2H-imidazole

C6H4N4 (132.0436)


   

N~2~-Formyl-L-serinamide

N~2~-Formyl-L-serinamide

C4H8N2O3 (132.0535)


   

3,4-Dihydroxy-2-methylenebutyric acid

3,4-Dihydroxy-2-methylenebutyric acid

C5H8O4 (132.0423)


   

N-carbamoyl-alanine

N-carbamoyl-alanine

C4H8N2O3 (132.0535)


   

108-59-8

PROPANEDIOIC ACID,DIMETHYL ESTER (MALONIC ACID,DIMETHYL ESTER)

C5H8O4 (132.0423)


Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1]. Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1].

   

AI3-03389

Succinic acid, monomethyl ester (8CI)

C5H8O4 (132.0423)


   

H-Gly-Gly-OH

L-Isoleucyl-L-proline

C4H8N2O3 (132.0535)


A dipeptide found in urine (PMID: 3782411). This is a proteolytic breakdown product of larger proteins. [HMDB] Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor.

   

(2S)-4-amino-2-ammonio-4-oxobutanoate

(2S)-4-amino-2-ammonio-4-oxobutanoate

C4H8N2O3 (132.0535)


   

[(Ammonioacetyl)amino]acetate

[(Ammonioacetyl)amino]acetate

C4H8N2O3 (132.0535)


   

(2R)-4-amino-2-azaniumyl-4-oxobutanoate

(2R)-4-amino-2-azaniumyl-4-oxobutanoate

C4H8N2O3 (132.0535)


   

2-Deoxy-ribono-1,5-lactone

2-Deoxy-ribono-1,5-lactone

C5H8O4 (132.0423)


   

N-(carboxylatoaminomethyl)urea

N-(carboxylatoaminomethyl)urea

C3H6N3O3- (132.0409)


   

(Z)-2,4-dihydroxypent-2-enoic acid

(Z)-2,4-dihydroxypent-2-enoic acid

C5H8O4 (132.0423)


   

(4R,5S)-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

(4R,5S)-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

C5H8O4 (132.0423)


   

3-Deoxy-d-glycero-pentos-2-ulose

3-Deoxy-d-glycero-pentos-2-ulose

C5H8O4 (132.0423)


   

2-Deoxy-d-glycero-pentos-3-ulose

2-Deoxy-d-glycero-pentos-3-ulose

C5H8O4 (132.0423)


   

4-Hydroxy-3-methyl-2-oxobutanoic acid

4-Hydroxy-3-methyl-2-oxobutanoic acid

C5H8O4 (132.0423)


   

1,1,3,3-Tetramethyldisiloxane

1,1,3,3-Tetramethyldisiloxane

C4H12OSi2 (132.0427)


   

MALONIC ACID DIMETHYL ESTER (1,1,1,7,7,7-D6)

MALONIC ACID DIMETHYL ESTER (1,1,1,7,7,7-D6)

C5H8O4 (132.0423)


   

Glycylglycine

Glycylglycine

C4H8N2O3 (132.0535)


A dipeptide formed from glycine residues. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor.

   

Ethyl methyl(nitroso)carbamate

Ethyl methyl(nitroso)carbamate

C4H8N2O3 (132.0535)


D009676 - Noxae > D000477 - Alkylating Agents

   

D-Asparagine

D-(-)-Asparagine monohydrate

C4H8N2O3 (132.0535)


An optically active form of asparagine having D-configuration.

   

2-acetyllactic acid

2-hydroxy-2-methyl-3-oxobutanoic acid

C5H8O4 (132.0423)


A derivative of butyric acid having methyl, hydroxy and oxo substituents at the 2-, 2- and 3-positions respectively.

   

2-Fluorobenzamide

N-Carbamoylsarcosine

C4H8N2O3 (132.0535)


   

(2S)-2-hydroxy-2-methyl-3-oxobutanoic acid

(2S)-2-hydroxy-2-methyl-3-oxobutanoic acid

C5H8O4 (132.0423)


D018377 - Neurotransmitter Agents > D018847 - Opioid Peptides D018377 - Neurotransmitter Agents > D004399 - Dynorphins

   

PTERIDINE

PTERIDINE

C6H4N4 (132.0436)


   

4-Hydroxy-2-oxopentanoic acid

4-Hydroxy-2-oxopentanoic acid

C5H8O4 (132.0423)


   

Monomethyl succinate

4-Methoxy-4-oxobutanoic acid

C5H8O4 (132.0423)


   

glycylglycine zwitterion

glycylglycine zwitterion

C4H8N2O3 (132.0535)


The zwitterion from the dipeptide glycylglycine formed by proton transfer from the OH of the carboxy group to the terminal amino group.

   

D-asparagine zwitterion

D-asparagine zwitterion

C4H8N2O3 (132.0535)


A D-alpha-amino acid zwitterion that is D-asparagine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3.

   

L-asparagine zwitterion

L-asparagine zwitterion

C4H8N2O3 (132.0535)


Zwitterionic form of L-asparagine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3.

   

(4S)-4-hydroxy-2-oxopentanoic acid

(4S)-4-hydroxy-2-oxopentanoic acid

C5H8O4 (132.0423)


   

(2S)-2-methylbutanedioic acid

(2S)-2-methylbutanedioic acid

C5H8O4 (132.0423)


   

2-Hydroxy-4-oxopentanoic acid

PENTANOIC ACID, 2-HYDROXY-4-OXO-

C5H8O4 (132.0423)


   

4-hydroxy-5-(hydroxymethyl)oxolan-2-one

4-hydroxy-5-(hydroxymethyl)oxolan-2-one

C5H8O4 (132.0423)


   

(S)-4-hydroxy-2-oxopentanoic acid

(S)-4-hydroxy-2-oxopentanoic acid

C5H8O4 (132.0423)


An optically active form of 4-hydroxy-2-oxopentanoic acid having 4S-configuration.

   

Acetolactate

Acetolactate

C5H8O4 (132.0423)


   

N-Carbamoylalanine

N-Carbamoylalanine

C4H8N2O3 (132.0535)


   

2,3-dihydroxy-2-methyl-butyolactone

NA

C5H8O4 (132.0423)


{"Ingredient_id": "HBIN004042","Ingredient_name": "2,3-dihydroxy-2-methyl-butyolactone","Alias": "NA","Ingredient_formula": "C5H8O4","Ingredient_Smile": "CC1(C(COC1=O)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "6026","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}

   

5-deoxy-1,4-lyxonolactone; l-form

NA

C5H8O4 (132.0423)


{"Ingredient_id": "HBIN011512","Ingredient_name": "5-deoxy-1,4-lyxonolactone; l-form","Alias": "NA","Ingredient_formula": "C5H8O4","Ingredient_Smile": "NA","Ingredient_weight": "132.11","OB_score": "NA","CAS_id": "248256-29-3","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7686","PubChem_id": "NA","DrugBank_id": "NA"}

   

d(-)-asparagine monohydrate

d(-)-asparagine monohydrate

C4H8N2O3 (132.0535)


   

4,5-dihydroxy-2,3-pentanedione

4,5-dihydroxy-2,3-pentanedione

C5H8O4 (132.0423)


   

[(2-amino-1-hydroxyethylidene)amino]acetic acid

[(2-amino-1-hydroxyethylidene)amino]acetic acid

C4H8N2O3 (132.0535)


   

succinamic acid, 3-amino-

succinamic acid, 3-amino-

C4H8N2O3 (132.0535)


   

(3s)-3-amino-3-(c-hydroxycarbonimidoyl)propanoic acid

(3s)-3-amino-3-(c-hydroxycarbonimidoyl)propanoic acid

C4H8N2O3 (132.0535)


   

(3s,4r)-3,4-dihydroxy-3-methyloxolan-2-one

(3s,4r)-3,4-dihydroxy-3-methyloxolan-2-one

C5H8O4 (132.0423)


   

(3r,4r)-3,4-dihydroxy-3-methyloxolan-2-one

(3r,4r)-3,4-dihydroxy-3-methyloxolan-2-one

C5H8O4 (132.0423)