N-NITROSO-N-METHYLURETHANE (BioDeep_00000012743)

 

Secondary id: BioDeep_00001868476

human metabolite blood metabolite


代谢物信息卡片


N-methyl-N-oxoethoxycarbohydrazide

化学式: C4H8N2O3 (132.05348980000002)
中文名称: N-甲基-N-亚硝基尿烷
谱图信息: 最多检出来源 Homo sapiens(blood) 22.22%

分子结构信息

SMILES: CCOC(=O)N(C)N=O
InChI: InChI=1S/C4H8N2O3/c1-3-9-4(7)6(2)5-8/h3H2,1-2H3

描述信息

D009676 - Noxae > D000477 - Alkylating Agents

同义名列表

6 个代谢物同义名

N-methyl-N-oxoethoxycarbohydrazide; Ethyl methyl(nitroso)carbamate; ethyl N-methylnitrosocarbamate; N-NITROSO-N-METHYLURETHANE; Nitrosomethylurethane; Methylnitrosourethane



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Soo-Seong Lee, Sun-Ae Lee, Jungmin Yang, Jongkee Kim. Developing stable progenies of ×Brassicoraphanus, an intergeneric allopolyploid between Brassica rapa and Raphanus sativus, through induced mutation using microspore culture. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2011 Mar; 122(5):885-91. doi: 10.1007/s00122-010-1494-3. [PMID: 21113703]
  • J R Homberg, J D A Olivier, B M G Smits, J D Mul, J Mudde, M Verheul, O F M Nieuwenhuizen, A R Cools, E Ronken, T Cremers, A N M Schoffelmeer, B A Ellenbroek, E Cuppen. Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system. Neuroscience. 2007 Jun; 146(4):1662-76. doi: 10.1016/j.neuroscience.2007.03.030. [PMID: 17467186]
  • Vincent Dive, Kumari L Andarawewa, Anne Boulay, Magdalini Matziari, Fabrice Beau, Eric Guerin, Bernard Rousseau, Athanasios Yiotakis, Marie-Christine Rio. Dosing and scheduling influence the antitumor efficacy of a phosphinic peptide inhibitor of matrix metalloproteinases. International journal of cancer. 2005 Feb; 113(5):775-81. doi: 10.1002/ijc.20459. [PMID: 15499617]
  • Jaret L Malloy, Jo Rae Wright. In vivo clearance of surfactant lipids during acute pulmonary inflammation. Respiratory research. 2004 Jul; 5(?):8. doi: 10.1186/1465-9921-5-8. [PMID: 15357882]
  • P S Puligandla, T Gill, L A McCaig, L J Yao, R A Veldhuizen, F Possmayer, J F Lewis. Alveolar environment influences the metabolic and biophysical properties of exogenous surfactants. Journal of applied physiology (Bethesda, Md. : 1985). 2000 Mar; 88(3):1061-71. doi: 10.1152/jappl.2000.88.3.1061. [PMID: 10710404]
  • M Ikegami, T R Korfhagen, J A Whitsett, M D Bruno, S E Wert, K Wada, A H Jobe. Characteristics of surfactant from SP-A-deficient mice. The American journal of physiology. 1998 08; 275(2):L247-54. doi: 10.1152/ajplung.1998.275.2.l247. [PMID: 9700084]
  • T Ueda, M Ikegami. Change in properties of exogenous surfactant in injured rabbit lung. American journal of respiratory and critical care medicine. 1996 Jun; 153(6 Pt 1):1844-9. doi: 10.1164/ajrccm.153.6.8665044. [PMID: 8665044]
  • J Lewis, M Ikegami, R Higuchi, A Jobe, D Absolom. Nebulized vs. instilled exogenous surfactant in an adult lung injury model. Journal of applied physiology (Bethesda, Md. : 1985). 1991 Oct; 71(4):1270-6. doi: 10.1152/jappl.1991.71.4.1270. [PMID: 1757348]
  • D F Liau, C R Barrett, A L Bell, S F Ryan. Functional abnormalities of lung surfactant in experimental acute alveolar injury in the dog. The American review of respiratory disease. 1987 Aug; 136(2):395-401. doi: 10.1164/ajrccm/136.2.395. [PMID: 3619199]
  • D F Liau, C R Barrett, A L Bell, S F Ryan. Normal surface properties of phosphatidylglycerol-deficient surfactant from dog after acute lung injury. Journal of lipid research. 1985 Nov; 26(11):1338-44. doi: 10.1016/s0022-2275(20)34260-7. [PMID: 3840829]
  • D F Liau, C R Barrett, A L Bell, G Cernansky, S F Ryan. Diphosphatidylglycerol in experimental acute alveolar injury in the dog. Journal of lipid research. 1984 Jul; 25(7):678-83. doi: 10.1016/s0022-2275(20)37756-7. [PMID: 6481242]
  • F L Glauser, R K Falls, J A Mathers, J E Millen. Pulmonary microvascular and alveolar epithelial permeability characteristics in N-nitroso-N-methylurethane-injected dogs. Chest. 1981 Feb; 79(2):217-21. doi: 10.1378/chest.79.2.217. [PMID: 6161758]
  • T Kokubu, E Ueda, T Joh, K Nishimura. Purification and properties of angiotensin I-converting enzyme in human lung and its role on the metabolism of vasoactive peptides in pulmonary circulation. Advances in experimental medicine and biology. 1979; 120B(?):467-75. doi: NULL. [PMID: 229710]
  • R Preussmann, R Deutsch-Wenzel, G Eisenbrand. The effect of heavy metal ions on the rate of decomposition of N-ethyl-N-nitrosourea and other carcinogenic N-nitrosamides. Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology. 1975 Sep; 84(1):75-80. doi: 10.1007/bf00305691. [PMID: 242130]