AI3-03389 (BioDeep_00000870606)
代谢物信息卡片
化学式: C5H8O4 (132.0423)
中文名称: 丁二酸单甲酯, 琥珀酸单甲酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC(=O)CCC(=O)O
InChI: InChI=1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)
描述信息
同义名列表
21 个代谢物同义名
Succinic acid, monomethyl ester (8CI); Butanedioic acid, monomethyl ester; Succinic acid, monomethyl ester; mono-Methyl hydrogen succinate; Succinic acid monomethyl ester; 4-methoxy-4-oxo-butanoic acid; 4-keto-4-methoxy-butyric acid; 3-Carbomethoxypropanoic acid; 4-Methoxy-4-oxobutanoic acid; Methyl hydrogen succinate; Monomethyl succinate; EINECS 223-408-2; M81101_ALDRICH; ARONIS006766; 14193_FLUKA; ALD-N007777; AI3-03389; 3878-55-5; NSC 511; NSC511; Monomethyl succinate
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 33090 - 月季花: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ying Xiong, Ke-Zhong Deng, Wen-Yuan Gao, Yuan-Qiang Guo. [Studies on chemical constituents of Ranunculus ternatus].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Apr; 33(8):909-11. doi:
". [PMID: 18619350] - Emma Heart, Gordon C Yaney, Richard F Corkey, Vera Schultz, Esthere Luc, Lihan Liu, Jude T Deeney, Orian Shirihai, Keith Tornheim, Peter J S Smith, Barbara E Corkey. Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose.
The Biochemical journal.
2007 Apr; 403(1):197-205. doi:
10.1042/bj20061209. [PMID: 17181533] - Michael J MacDonald. Synergistic potent insulin release by combinations of weak secretagogues in pancreatic islets and INS-1 cells.
The Journal of biological chemistry.
2007 Mar; 282(9):6043-52. doi:
10.1074/jbc.m606652200. [PMID: 17210580] - Christophe Marin, Christine Schippa. Identification of monomenthyl succinate in natural mint extracts by LC-ESI-MS-MS and GC-MS.
Journal of agricultural and food chemistry.
2006 Jun; 54(13):4814-9. doi:
10.1021/jf060729c. [PMID: 16787033] - A Farret, M Vignaud, S Dietz, J Vignon, P Petit, R Gross. P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism.
Diabetes.
2004 Dec; 53 Suppl 3(?):S63-6. doi:
10.2337/diabetes.53.suppl_3.s63. [PMID: 15561924] - Hans Ehrsson, Inger Wallin. Liquid chromatographic determination of oxaliplatin in blood using post-column derivatization in a microwave field followed by photometric detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Oct; 795(2):291-4. doi:
10.1016/s1570-0232(03)00590-7. [PMID: 14522033] - Isabelle Briaud, Cynthia L Kelpe, Lisa M Johnson, Phuong Oanh T Tran, Vincent Poitout. Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats.
Diabetes.
2002 Mar; 51(3):662-8. doi:
10.2337/diabetes.51.3.662. [PMID: 11872664] - P Maechler, L Jornot, C B Wollheim. Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.
The Journal of biological chemistry.
1999 Sep; 274(39):27905-13. doi:
10.1074/jbc.274.39.27905. [PMID: 10488138] - L Ladrière, W J Malaisse. Nutritional value of succinic acid monoethyl ester in starvation.
Annals of nutrition & metabolism.
1997; 41(2):118-25. doi:
10.1159/000177987. [PMID: 9267586] - F Malaisse-Lagae, A Bakkali Nadi, W J Malaisse. Insulinotropic response to enterally administered succinic and glutamic acid methyl esters.
Archives internationales de pharmacodynamie et de therapie.
1994 Sep; 328(2):235-42. doi:
NULL. [PMID: 7710308] - D Vicent, M L Villanueva-Peñacarrillo, I Valverde, W J Malaisse. Impaired in vivo insulin secretion in response to non-glucidic secretagogues in adult rats after neonatal streptozotocin.
Acta diabetologica.
1994 Sep; 31(3):133-7. doi:
10.1007/bf00570366. [PMID: 7827350] - D Vicent, M L Villanueva-Penacarrillo, F Malaisse-Lagae, V Leclercq-Meyer, I Valverde, W J Malaisse. In vivo stimulation of insulin release by succinic acid methyl esters.
Archives internationales de pharmacodynamie et de therapie.
1994 Mar; 327(2):246-50. doi:
NULL. [PMID: 7979832] - A R Karuri, E Dobrowsky, I F Tannock. Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment.
British journal of cancer.
1993 Dec; 68(6):1080-7. doi:
10.1038/bjc.1993.485. [PMID: 8260358] - E Maeda, M Matsuo, K Saiki, H Nakamura, T Matsuo, H Takemine. Methylsuccinate and mesaconate in urine of patients treated with sodium benzoate.
Acta paediatrica Japonica : Overseas edition.
1989 Dec; 31(6):721-6. doi:
10.1111/j.1442-200x.1989.tb01386.x. [PMID: 2533792] - P A Wood, B A Amendt, W J Rhead, D S Millington, F Inoue, D Armstrong. Short-chain acyl-coenzyme A dehydrogenase deficiency in mice.
Pediatric research.
1989 Jan; 25(1):38-43. doi:
10.1203/00006450-198901000-00010. [PMID: 2919115] - S R Gullans, B C Kone, M J Avison, G Giebisch. Succinate alters respiration, membrane potential, and intracellular K+ in proximal tubule.
The American journal of physiology.
1988 Dec; 255(6 Pt 2):F1170-7. doi:
10.1152/ajprenal.1988.255.6.f1170. [PMID: 3202180] - K S Chen, H A Lardy. 3-Aminopicolinate inhibits phosphoenolpyruvate carboxykinase in hepatocytes and increases release of gluconeogenic precursors from peripheral tissues.
The Journal of biological chemistry.
1984 Jun; 259(11):6920-4. doi:
10.1016/s0021-9258(17)39815-0. [PMID: 6725275] - K J Ullrich, H Fasold, G Rumrich, S Klöss. Secretion and contraluminal uptake of dicarboxylic acids in the proximal convolution of rat kidney.
Pflugers Archiv : European journal of physiology.
1984 Mar; 400(3):241-9. doi:
10.1007/bf00581554. [PMID: 6728645] - G Fritzsch, W Haase, G Rumrich, H Fasold, K J Ullrich. A stopped flow capillary perfusion method to evaluate contraluminal transport parameters of methylsuccinate from interstitium into renal proximal tubular cells.
Pflugers Archiv : European journal of physiology.
1984 Mar; 400(3):250-6. doi:
10.1007/bf00581555. [PMID: 6728646]
