THIORPHAN (BioDeep_00001868906)

Main id: BioDeep_00000004725

 


代谢物信息卡片


THIORPHAN

化学式: C12H15NO3S (253.07726)
中文名称: 3-巯基-2苄基丙基甘氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)CC(CS)C(=O)NCC(=O)O
InChI: InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)

描述信息

D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors

同义名列表

1 个代谢物同义名

THIORPHAN



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Lan Li, Chenlin Shen, Lian Tang, Yanxia Yu, Qin Zhou, Xiaohui Huang, Sudong Xue. Determination of thiorphan, a racecadotril metabolite, in human plasma by LC-MS/MS and its application to a bioequivalence study in Chinese subjects
. International journal of clinical pharmacology and therapeutics. 2020 Jul; 58(7):408-414. doi: 10.5414/cp203588. [PMID: 32352368]
  • Peter Serfozo, Jan Wysocki, Gvantca Gulua, Arndt Schulze, Minghao Ye, Pan Liu, Jing Jin, Michael Bader, Timo Myöhänen, J Arturo García-Horsman, Daniel Batlle. Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent. Hypertension (Dallas, Tex. : 1979). 2020 01; 75(1):173-182. doi: 10.1161/hypertensionaha.119.14071. [PMID: 31786979]
  • Vajir Malek, Nisha Sharma, Anil Bhanudas Gaikwad. Simultaneous inhibition of neprilysin and activation of ACE2 prevented diabetic cardiomyopathy. Pharmacological reports : PR. 2019 Oct; 71(5):958-967. doi: 10.1016/j.pharep.2019.05.008. [PMID: 31470292]
  • Vajir Malek, Nisha Sharma, Himanshu Sankrityayan, Anil Bhanudas Gaikwad. Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy. Life sciences. 2019 Mar; 221(?):159-167. doi: 10.1016/j.lfs.2019.02.027. [PMID: 30769114]
  • R Murray McKinnell, Paul Fatheree, Seok-Ki Choi, Roland Gendron, Keith Jendza, Brooke Olson Blair, Joe Budman, Craig M Hill, Laxminarayan G Hegde, Cecile Yu, Donavon McConn, Sharath S Hegde, Daniel G Marquess, Uwe Klein. Discovery of TD-0212, an Orally Active Dual Pharmacology AT1 Antagonist and Neprilysin Inhibitor (ARNI). ACS medicinal chemistry letters. 2019 Jan; 10(1):86-91. doi: 10.1021/acsmedchemlett.8b00462. [PMID: 30655952]
  • Lodi C W Roksnoer, Estrellita Uijl, René de Vries, Ingrid M Garrelds, A H Jan Danser. Neprilysin inhibition and endothelin-1 elevation: Focus on the kidney. European journal of pharmacology. 2018 Apr; 824(?):128-132. doi: 10.1016/j.ejphar.2018.02.007. [PMID: 29432709]
  • Oliver Domenig, Arndt Manzel, Nadja Grobe, Eva Königshausen, Christopher C Kaltenecker, Johannes J Kovarik, Johannes Stegbauer, Susan B Gurley, Dunja van Oyen, Marlies Antlanger, Michael Bader, Daisy Motta-Santos, Robson A Santos, Khalid M Elased, Marcus D Säemann, Ralf A Linker, Marko Poglitsch. Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney. Scientific reports. 2016 09; 6(?):33678. doi: 10.1038/srep33678. [PMID: 27649628]
  • David W Griggs, Michael J Prinsen, Jonathan Oliva, Mary A Campbell, Stacy D Arnett, Deena Tajfirouz, Peter G Ruminski, Ying Yu, Brian R Bond, Yuhua Ji, Georg Neckermann, Robert K M Choy, Eugenio de Hostos, Marvin J Meyers. Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea. The Journal of pharmacology and experimental therapeutics. 2016 May; 357(2):423-31. doi: 10.1124/jpet.115.231167. [PMID: 26907621]
  • Lodi C W Roksnoer, Richard van Veghel, René de Vries, Ingrid M Garrelds, Usha M Bhaggoe, Edith C H Friesema, Frank P J Leijten, Marko Poglitsch, Oliver Domenig, Marian C Clahsen-van Groningen, Ewout J Hoorn, A H Jan Danser, Wendy W Batenburg. Optimum AT1 receptor-neprilysin inhibition has superior cardioprotective effects compared with AT1 receptor blockade alone in hypertensive rats. Kidney international. 2015 Jul; 88(1):109-20. doi: 10.1038/ki.2015.107. [PMID: 25830765]
  • Raphaëlle Pelc, Sébastien Redant, Sébastien Julliand, Juan Llor, Mathie Lorrot, Rianne Oostenbrink, Vincent Gajdos, François Angoulvant. Pediatric gastroenteritis in the emergency department: practice evaluation in Belgium, France, The Netherlands and Switzerland. BMC pediatrics. 2014 May; 14(?):125. doi: 10.1186/1471-2431-14-125. [PMID: 24884619]
  • Jean-Nicholas Mess, Marie-Pierre Taillon, Cynthia Côté, Fabio Garofolo. Dried blood spot on-card derivatization: an alternative form of sample handling to overcome the instability of thiorphan in biological matrix. Biomedical chromatography : BMC. 2012 Dec; 26(12):1617-24. doi: 10.1002/bmc.2745. [PMID: 22511292]
  • Yung-Hua Koh, Shabbir Moochhala, Madhav Bhatia. The role of neutral endopeptidase in caerulein-induced acute pancreatitis. Journal of immunology (Baltimore, Md. : 1950). 2011 Nov; 187(10):5429-39. doi: 10.4049/jimmunol.1102011. [PMID: 22013111]
  • Philippe Lehert, Gérard Chéron, Guillermo Alvarez Calatayud, Jean-Pierre Cézard, Pedro Gutierrez Castrellón, José-Manuel Meléndez Garcia, Mar Santos, M R Savitha. Racecadotril for childhood gastroenteritis: an individual patient data meta-analysis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 2011 Sep; 43(9):707-13. doi: 10.1016/j.dld.2011.03.001. [PMID: 21514257]
  • J-P Lee, K-C Cheng, H-H Chung, H-T Wu, C-T Chen, J-T Cheng. Inhibition of insulin degrading enzyme by racecadotril in the brain of Wistar rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2011 Jun; 43(7):489-93. doi: 10.1055/s-0031-1277183. [PMID: 21557151]
  • H T Wu, C K Chang, K C Cheng, C H Chang, C H Yeh, J T Cheng. Increase of plasma insulin by racecadotril, an inhibitor of enkephalinase, in Wistar rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2010 Apr; 42(4):261-7. doi: 10.1055/s-0029-1246190. [PMID: 20143290]
  • Takayuki Matsumoto, Yuta Ozawa, Kumiko Taguchi, Tsuneo Kobayashi, Katsuo Kamata. Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction. Peptides. 2010 Feb; 31(2):346-53. doi: 10.1016/j.peptides.2009.11.029. [PMID: 19962413]
  • Flavia Axelband, Juliana Dias, Filipe Miranda, Fernanda M Ferrão, Nilana M Barros, Adriana K Carmona, Lucienne S Lara, Adalberto Vieyra. A scrutiny of the biochemical pathways from Ang II to Ang-(3-4) in renal basolateral membranes. Regulatory peptides. 2009 Nov; 158(1-3):47-56. doi: 10.1016/j.regpep.2009.08.004. [PMID: 19703499]
  • Kanetaka Maeshiro, Shinzo Takamori, Hiroharu Mifune, Toshihiro Matsuo, Norman Y Kimura, Junichi Honda, Kazuo Shirouzu. Changes in A-type natriuretic peptide and its receptors induced by a neutral endopeptidase inhibitor in a rat model of sepsis. Surgery today. 2008; 38(2):130-4. doi: 10.1007/s00595-007-3586-5. [PMID: 18239869]
  • Fan Xu, Lingli Yang, Guili Xu. A rapid and validated HPLC method to quantify racecadotril metabolite, thiorphan, in human plasma using solid-phase extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2008 Jan; 861(1):130-5. doi: 10.1016/j.jchromb.2007.11.038. [PMID: 18083074]
  • Yu Xu, Jinchang Huang, Fei Liu, Shu Gao, Qingxiang Guo. Quantitative analysis of racecadotril metabolite in human plasma using a liquid chromatography/tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Jun; 852(1-2):101-7. doi: 10.1016/j.jchromb.2006.12.041. [PMID: 17241825]
  • Giovanni Sansoè, Manuela Aragno, Raffaella Mastrocola, Francesca Restivo, Giulio Mengozzi, Antonina Smedile, Floriano Rosina, Oliviero Danni, Maurizio Parola, Mario Rizzetto. Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?. Journal of hepatology. 2005 Nov; 43(5):791-8. doi: 10.1016/j.jhep.2005.04.017. [PMID: 16085334]
  • Christoph Schmid, Claudia Ghirlanda-Keller, Martina Gosteli-Peter. Ascorbic acid decreases neutral endopeptidase activity in cultured osteoblastic cells. Regulatory peptides. 2005 Aug; 130(1-2):57-66. doi: 10.1016/j.regpep.2005.03.007. [PMID: 15908023]
  • Marie-Hélène Fecteau, Jean-Claude Honoré, Mirco Plante, Julie Labonté, Giles A Rae, Pedro D'Orléans-Juste. Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension (Dallas, Tex. : 1979). 2005 Jul; 46(1):87-92. doi: 10.1161/01.hyp.0000170460.24604.23. [PMID: 15956117]
  • Anthony C Sulpizio, Mark A Pullen, Richard M Edwards, David P Brooks. The effect of acute angiotensin-converting enzyme and neutral endopeptidase 24.11 inhibition on plasma extravasation in the rat. The Journal of pharmacology and experimental therapeutics. 2004 Jun; 309(3):1141-7. doi: 10.1124/jpet.103.064105. [PMID: 14769834]
  • Catherine Rougeot, Michaël Messaoudi, Véronique Hermitte, Anne Gaëlle Rigault, Thierry Blisnick, Christophe Dugave, Didier Desor, François Rougeon. Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity. Proceedings of the National Academy of Sciences of the United States of America. 2003 Jul; 100(14):8549-54. doi: 10.1073/pnas.1431850100. [PMID: 12835417]
  • K S Park, Y Li, Y Zhang, A L Gerbes, H Liu, M G Swain, S S Lee. Effects of the neutral endopeptidase inhibitor thiorphan on cardiovascular and renal function in cirrhotic rats. British journal of pharmacology. 2003 May; 139(1):81-8. doi: 10.1038/sj.bjp.0705219. [PMID: 12746226]
  • S Huighebaert, F Awouters, G N J Tytgat. Racecadotril versus loperamide: antidiarrheal research revisited. Digestive diseases and sciences. 2003 Feb; 48(2):239-50. doi: 10.1023/a:1021989606317. [PMID: 12643598]
  • François Piquard, Ruddy Richard, Anne Charloux, Stephane Doutreleau, Thierry Hannedouche, Gabrielle Brandenberger, Bernard Geny. Hormonal, renal, hemodynamic responses to acute neutral endopeptidase inhibition in heart transplant patients. Journal of applied physiology (Bethesda, Md. : 1985). 2002 Aug; 93(2):569-75. doi: 10.1152/japplphysiol.00027.2002. [PMID: 12133866]
  • A Chevrier, J S Mort, P Crine, C D Hoemann, M D Buschmann. Soluble recombinant neprilysin induces aggrecanase-mediated cleavage of aggrecan in cartilage explant cultures. Archives of biochemistry and biophysics. 2001 Dec; 396(2):178-86. doi: 10.1006/abbi.2001.2608. [PMID: 11747295]
  • G Capasso, R Unwin, F Ciani, A Rizzo, F Russo, A Pica, N G De Santo. Inhibition of neutral endopeptidase potentiates the effects of atrial natriuretic peptide on acute cyclosporin-induced nephrotoxicity. Nephron. 2000 Nov; 86(3):298-305. doi: 10.1159/000045785. [PMID: 11096287]
  • E Salazar-Lindo, J Santisteban-Ponce, E Chea-Woo, M Gutierrez. Racecadotril in the treatment of acute watery diarrhea in children. The New England journal of medicine. 2000 Aug; 343(7):463-7. doi: 10.1056/nejm200008173430703. [PMID: 10944563]
  • G Freyer, P Rougier, R Bugat, J P Droz, M Marty, H Bleiberg, D Mignard, L Awad, P Herait, S Culine, V Trillet-Lenoir. Prognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5FU failure. CPT-11 F205, F220, F221 and V222 study groups. British journal of cancer. 2000 Aug; 83(4):431-7. doi: 10.1054/bjoc.2000.1303. [PMID: 10945486]
  • Y Takeda, S Inaba, K Furukawa, A Fujimura, I Miyamori, H Mabuchi. Effects of chronic neutral endopeptidase inhibition in rats with cyclosporine-induced hypertension. Journal of hypertension. 2000 Jul; 18(7):927-33. doi: 10.1097/00004872-200018070-00015. [PMID: 10930191]
  • P Solter, D Sisson, W Thomas, L Goetze. Intrarenal effects of ecadotril during acute volume expansion in dogs with congestive heart failure. The Journal of pharmacology and experimental therapeutics. 2000 Jun; 293(3):989-95. doi: NULL. [PMID: 10869402]
  • T Maertins, E von Keutz, L Goetze. Acute, subchronic, and chronic toxicity of ecadotril in dogs. American journal of veterinary research. 2000 Apr; 61(4):425-9. doi: 10.2460/ajvr.2000.61.425. [PMID: 10772108]
  • N B Olivier, S M Kutas, S Beals, B Hanson, S Windram. Short-term effects of ecadotril in dogs with induced congestive heart failure. American journal of veterinary research. 2000 Mar; 61(3):333-8. doi: 10.2460/ajvr.2000.61.333. [PMID: 10714529]
  • M B Pamnani, S Chen, H J Bryant, J F Schooley, F J Haddy, R D Ghai. Effects of a neutral endoprotease enzyme inhibitor, thiorphan, on hemodynamics and renal excretory function in four models of experimental hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993). 2000 Jan; 22(1):45-62. doi: 10.1081/ceh-100100061. [PMID: 10685724]
  • C M O'Connor, W A Gattis, M Gheorghiade, C B Granger, J Gilbert, J M McKenney, F C Messineo, J C Burnett, S D Katz, U Elkayam, E K Kasper, S Goldstein, R J Cody, B M Massie. A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: the U.S. ecadotril pilot safety study. American heart journal. 1999 Dec; 138(6 Pt 1):1140-8. doi: 10.1016/s0002-8703(99)70081-5. [PMID: 10577446]
  • G Prasanna, A Dibas, A Finkley, T Yorio. Identification of endothelin converting enzyme-1 in human non-pigmented ciliary epithelial cells. Experimental eye research. 1999 Aug; 69(2):175-83. doi: 10.1006/exer.1999.0691. [PMID: 10433854]
  • Y Takagawa, N Ura, M Nanba, J Agata, K Higashiura, T Torii, M Takada, K Shimamoto. The contribution of nitric oxide to diuretic and natriuretic effects of renal kinins in normotensive rats. Hypertension research : official journal of the Japanese Society of Hypertension. 1999 Jul; 22(2):129-34. doi: 10.1291/hypres.22.129. [PMID: 10487329]
  • H Beaulieu, A Elagöz, P Crine, L A Rokeach. Interaction of mammalian neprilysin with binding protein and calnexin in Schizosaccharomyces pombe. The Biochemical journal. 1999 Jun; 340 ( Pt 3)(?):813-9. doi: 10.1042/bj3400813. [PMID: 10359668]
  • J Ozaki, H Shimizu, Y Hashimoto, H Itoh, K Nakao, K Inui. Enzymatic inactivation of major circulating forms of atrial and brain natriuretic peptides. European journal of pharmacology. 1999 Apr; 370(3):307-12. doi: 10.1016/s0014-2999(99)00115-6. [PMID: 10334507]
  • A M Duncan, G M James, F Anastasopoulos, A Kladis, T A Briscoe, D J Campbell. Interaction between neutral endopeptidase and angiotensin converting enzyme inhibition in rats with myocardial infarction: effects on cardiac hypertrophy and angiotensin and bradykinin peptide levels. The Journal of pharmacology and experimental therapeutics. 1999 Apr; 289(1):295-303. doi: NULL. [PMID: 10087017]
  • M F Hand, W G Haynes, D J Webb. Reduced endogenous endothelin-1-mediated vascular tone in chronic renal failure. Kidney international. 1999 Feb; 55(2):613-20. doi: 10.1046/j.1523-1755.1999.00291.x. [PMID: 9987085]
  • H Ito, M Majima, S Nakajima, I Hayashi, M Katori, T Izumi. Effect of prolonged administration of a urinary kinase inhibitor, ebelactone B on the development of deoxycorticosterone acetate-salt hypertension in rats. British journal of pharmacology. 1999 Feb; 126(3):613-20. doi: 10.1038/sj.bjp.0702340. [PMID: 10188971]
  • B L Koch, A A Edvinsson, L O Koskinen. Inhalation of substance P and thiorphan: acute toxicity and effects on respiration in conscious guinea pigs. Journal of applied toxicology : JAT. 1999 Jan; 19(1):19-23. doi: 10.1002/(sici)1099-1263(199901/02)19:1<19::aid-jat533>3.0.co;2-r. [PMID: 9989473]
  • J R Gontijo, L A Smith, U C Kopp. CGRP activates renal pelvic substance P receptors by retarding substance P metabolism. Hypertension (Dallas, Tex. : 1979). 1999 Jan; 33(1 Pt 2):493-8. doi: 10.1161/01.hyp.33.1.493. [PMID: 9931154]
  • E A Kuijpers, J den Hartigh, P Vermeij. A stability study involving HPLC analysis of aqueous thiorphan solutions in the presence of human serum albumin. Pharmaceutical development and technology. 1998 May; 3(2):185-92. doi: 10.3109/10837459809028494. [PMID: 9653755]
  • J K Vishwanatha, R G Davis, S Blumberg, X P Gao, I Rubinstein. Increased tissue neutral endopeptidase 24.11 activity in spontaneously hypertensive hamsters. American journal of hypertension. 1998 May; 11(5):585-90. doi: 10.1016/s0895-7061(98)00028-4. [PMID: 9633795]
  • J D Aubert, B Carnal, J Ricou, P Fioroni, L Juillerat-Jeanneret, F Pinet. Characterization of the enzyme involved in the processing of big endothelin-1 in human lung epithelial cells. Pulmonary pharmacology & therapeutics. 1998 Apr; 11(2-3):209-13. doi: 10.1006/pupt.1998.0140. [PMID: 9918758]
  • M Kimura, K Umemura, K Ohashi, M Nakashima. Effect of ecadotril, a neutral endopeptidase inhibitor, on myocardial hypertrophy in the rat aortic insufficiency model. The Canadian journal of cardiology. 1998 Jan; 14(1):63-8. doi: NULL. [PMID: 9487275]
  • S Nakajima, M Majima, H Ito, I Hayashi, Y Yajima, M Katori. Effects of a neutral endopeptidase inhibitor, BP102, on the development of deoxycorticosterone acetate-salt hypertension in kininogen-deficient Brown Norway Katholiek rats. International journal of tissue reactions. 1998; 20(2):45-56. doi: NULL. [PMID: 9638501]
  • X P Gao, H Suzuki, C O Olopade, S Pakhlevaniants, I Rubinstein. Angiotensin-converting enzyme and neutral endopeptidase modulate smokeless tobacco-induced increase in macromolecular efflux from the oral mucosa in vivo. The Journal of laboratory and clinical medicine. 1997 Oct; 130(4):395-400. doi: 10.1016/s0022-2143(97)90039-1. [PMID: 9358078]
  • T A Hinterleitner, W Petritsch, G Dimsity, H Berard, J M Lecomte, G J Krejs. Acetorphan prevents cholera-toxin-induced water and electrolyte secretion in the human jejunum. European journal of gastroenterology & hepatology. 1997 Sep; 9(9):887-91. doi: 10.1097/00042737-199709000-00012. [PMID: 9355788]
  • G M Ksander, R de Jesus, A Yuan, R D Ghai, A Trapani, C McMartin, R Bohacek. Ortho-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors. Journal of medicinal chemistry. 1997 Feb; 40(4):495-505. doi: 10.1021/jm960582o. [PMID: 9046340]
  • M Wegner, D Ganten, J P Stasch. Neutral endopeptidase inhibition potentiates the effects of natriuretic peptides in renin transgenic rats. Hypertension research : official journal of the Japanese Society of Hypertension. 1996 Dec; 19(4):229-38. doi: 10.1291/hypres.19.229. [PMID: 8986453]
  • J M Soleilhac, C Lafuma, J M Porcher, G Auburtin, B P Roques. Characterization of a soluble form of neutral endopeptidase-24.11 (EC 3.4.24.11) in human serum: enhancement of its activity in serum of underground miners exposed to coal dust particles. European journal of clinical investigation. 1996 Nov; 26(11):1011-7. doi: 10.1046/j.1365-2362.1996.2420580.x. [PMID: 8957208]
  • V L Tucker. Contribution of ANP to plasma protein escape during VE: effects of thiorphan and atrial appendectomy. The American journal of physiology. 1996 Sep; 271(3 Pt 2):R610-8. doi: 10.1152/ajpregu.1996.271.3.r610. [PMID: 8853382]
  • J P Stasch, C Hirth-Dietrich, D Ganten, M Wegner. Renal and antihypertensive effects of neutral endopeptidase inhibition in transgenic rats with an extra renin gene. American journal of hypertension. 1996 Aug; 9(8):795-802. doi: 10.1016/0895-7061(96)00099-4. [PMID: 8862226]
  • M Wegner, C Hirth-Dietrich, J P Stasch. Role of neutral endopeptidase 24.11 in AV fistular rat model of heart failure. Cardiovascular research. 1996 Jun; 31(6):891-8. doi: NULL. [PMID: 8759244]
  • K Barnes, K Shimada, M Takahashi, K Tanzawa, A J Turner. Metallopeptidase inhibitors induce an up-regulation of endothelin-converting enzyme levels and its redistribution from the plasma membrane to an intracellular compartment. Journal of cell science. 1996 May; 109 ( Pt 5)(?):919-28. doi: 10.1242/jcs.109.5.919. [PMID: 8743939]
  • H Tsushima, M Mori, T Matsuda. Peptidase inhibitor-induced antidiuresis mediated through angiotensin and opioid receptors in the rat hypothalamus. Japanese journal of pharmacology. 1996 May; 71(1):61-71. doi: 10.1254/jjp.71.61. [PMID: 8791172]
  • L Beaugerie, P Baumer, S Chaussade, H Berard, W Rozenbaum, G Pialoux, Y Le Quintrec, J C Schwartz, J M Lecomte. Treatment of refractory diarrhoea in AIDS with acetorphan and octreotide: a randomized crossover study. European journal of gastroenterology & hepatology. 1996 May; 8(5):485-9. doi: ". [PMID: 8804878]
  • I Pham, W Gonzalez, J Doucet, M C Fournie-Zaluski, B P Roques, J B Michel. Effects of angiotensin-converting enzyme and neutral endopeptidase inhibitors: influence of bradykinin. European journal of pharmacology. 1996 Feb; 296(3):267-76. doi: 10.1016/0014-2999(95)00706-7. [PMID: 8904078]
  • E P Masler, R M Wagner, E S Kovaleva. In vitro metabolism of an insect neuropeptide by neural membrane preparations from Lymantria dispar. Peptides. 1996; 17(2):321-6. doi: 10.1016/0196-9781(95)02098-5. [PMID: 8801540]
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