(20R)-20-hydroxypregn-4-en-3-one (BioDeep_00001868341)

Main id: BioDeep_00000637533

 

Volatile Flavor Compounds


代谢物信息卡片


Pregn-4-en-3-one,20-hydroxy-, (20S)-

化学式: C21H32O2 (316.24021719999996)
中文名称: 20β-二氢黄体酮, 二氢孕酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16+,17-,18+,19+,20+,21-/m1/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D011372 - Progestins

同义名列表

4 个代谢物同义名

(20R)-20-hydroxypregn-4-en-3-one; Pregn-4-en-3-one,20-hydroxy-, (20S)-; (20S)-20-hydroxypregn-4-en-3-one; 20alpha-Hydroxy-4-pregnen-3-one



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Cecilia Rustichelli, Emanuela Monari, Rossella Avallone, Elisa Bellei, Stefania Bergamini, Aldo Tomasi, Anna Ferrari. Dehydroepiandrosterone sulfate, dehydroepiandrosterone, 5α-dihydroprogesterone and pregnenolone in women with migraine: Analysis of serum levels and correlation with age, migraine years and frequency. Journal of pharmaceutical and biomedical analysis. 2021 Nov; 206(?):114388. doi: 10.1016/j.jpba.2021.114388. [PMID: 34597839]
  • Kristina M Deligiannidis, Aimee R Kroll-Desrosiers, Yanglan Tan, Michelle L Dubuke, Scott A Shaffer. Longitudinal proneuroactive and neuroactive steroid profiles in medication-free women with, without and at-risk for perinatal depression: A liquid chromatography-tandem mass spectrometry analysis. Psychoneuroendocrinology. 2020 11; 121(?):104827. doi: 10.1016/j.psyneuen.2020.104827. [PMID: 32828068]
  • Jie Wang, Xiang-Zhong Gu, Li-Ming He, Chen-Chen Li, Wen-Wei Qiu. Synthesis of ursodeoxycholic acid from plant-source (20S)-21-hydroxy-20-methylpregn-4-en-3-one. Steroids. 2020 05; 157(?):108600. doi: 10.1016/j.steroids.2020.108600. [PMID: 32068080]
  • Yu-Ling Wang, Wei Wu, Yong-Nan Su, Zhi-Peng Ai, Han-Chuan Mou, Luo-Sheng Wan, Ying Luo, Ming-Hua Qiu, Ji-Hong Zhang. Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Mar; 68(?):153187. doi: 10.1016/j.phymed.2020.153187. [PMID: 32097779]
  • Philippe Liere, Charlotte A Cornil, Marie Pierre de Bournonville, Antoine Pianos, Matthieu Keller, Michael Schumacher, Jacques Balthazart. Steroid profiles in quail brain and serum: Sex and regional differences and effects of castration with steroid replacement. Journal of neuroendocrinology. 2019 02; 31(2):e12681. doi: 10.1111/jne.12681. [PMID: 30585662]
  • Gaia Cermenati, Silvia Giatti, Matteo Audano, Marzia Pesaresi, Roberto Spezzano, Donatella Caruso, Nico Mitro, Roberto Cosimo Melcangi. Diabetes alters myelin lipid profile in rat cerebral cortex: Protective effects of dihydroprogesterone. The Journal of steroid biochemistry and molecular biology. 2017 04; 168(?):60-70. doi: 10.1016/j.jsbmb.2017.02.002. [PMID: 28167298]
  • Kristina M Deligiannidis, Aimee R Kroll-Desrosiers, Shunyan Mo, Hien P Nguyen, Abby Svenson, Nina Jaitly, Janet E Hall, Bruce A Barton, Anthony J Rothschild, Scott A Shaffer. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. Psychoneuroendocrinology. 2016 08; 70(?):98-107. doi: 10.1016/j.psyneuen.2016.05.010. [PMID: 27209438]
  • Erin L Legacki, Elizabeth L Scholtz, Barry A Ball, Scott D Stanley, Trish Berger, Alan J Conley. The dynamic steroid landscape of equine pregnancy mapped by mass spectrometry. Reproduction (Cambridge, England). 2016 Apr; 151(4):421-30. doi: 10.1530/rep-15-0547. [PMID: 26814209]
  • L V Bayunova. [THE EFFECT OF HORMONAL STIMULATION OF STERLET (ACIPENSER RUTHENUS L.) ON STEROID LEVELS IN TISSUE INCUBATES]. Zhurnal evoliutsionnoi biokhimii i fiziologii. 2016 Jan; 52(1):17-25. doi: 10.1134/s0022093016010026. [PMID: 27220236]
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  • Yonghua Zhang, Mélanie Nadeau, Frédérick Faucher, Odette Lescelleur, Simon Biron, Marleen Daris, Caroline Rhéaume, Van Luu-The, André Tchernof. Progesterone metabolism in adipose cells. Molecular and cellular endocrinology. 2009 Jan; 298(1-2):76-83. doi: 10.1016/j.mce.2008.09.034. [PMID: 18984031]
  • Pia Rantakari, Leena Strauss, Riku Kiviranta, Heidi Lagerbohm, Jenni Paviala, Irma Holopainen, Seppo Vainio, Pirjo Pakarinen, Matti Poutanen. Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene. Molecular endocrinology (Baltimore, Md.). 2008 Mar; 22(3):665-75. doi: 10.1210/me.2007-0257. [PMID: 18048640]
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