Oxandrolone (BioDeep_00001867867)
Main id: BioDeep_00000006481
Volatile Flavor Compounds
代谢物信息卡片
Oxandrolone
化学式: C19H30O3 (306.21948299999997)
中文名称: 氧甲氢龙
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCC3C(C1CCC2(C)O)CCC4C3(COC(=O)C4)C
InChI: InChI=1S/C19H30O3/c1-17-11-22-16(20)10-12(17)4-5-13-14(17)6-8-18(2)15(13)7-9-19(18,3)21/h12-15,21H,4-11H2,1-3H3/t12-,13+,14-,15-,17-,18-,19-/m0/s1
描述信息
A - Alimentary tract and metabolism > A14 - Anabolic agents for systemic use > A14A - Anabolic steroids > A14AA - Androstan derivatives
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
同义名列表
2 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:7820
- KEGG: C07346
- KEGGdrug: D00462
- PubChem: 5878
- DrugBank: DB00621
- ChEMBL: CHEMBL1200436
- MeSH: Oxandrolone
- CAS: 53-39-4
- PubChem: 9553
- NIKKAJI: J1.367F
- RefMet: Oxandrolone
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Caitlin Harding, Marjaana Viljanto, Charlotte Cutler, Jocelyn Habershon-Butcher, Simon Biddle, James Scarth. In vitro and in vivo metabolism of the anabolic-androgenic steroid oxandrolone in the horse.
Drug testing and analysis.
2022 Jan; 14(1):39-55. doi:
10.1002/dta.3139. [PMID: 34378336] - Emanuel Airton de Oliveira Farias, Nielson José Silva Furtado, Isaac Yves Lopes de Macêdo, Eric de Souza Gil, Freddy Fernandes Guimarães, Ruan Sousa Bastos, Jefferson Almeida Rocha, Lívio César Cunha Nunes, Roberto Alves de Sousa Luz, Carla Eiras. Poly(Alizarin Red S) on pyrolytic graphite electrodes as a new multi-electronic system for sensing oxandrolone in urine.
Biosensors & bioelectronics.
2021 Aug; 185(?):113234. doi:
10.1016/j.bios.2021.113234. [PMID: 33945892] - Flavio Cadegiani, Erica M Lin, Andy Goren, Carlos G Wambier. Potential risk for developing severe COVID-19 disease among anabolic steroid users.
BMJ case reports.
2021 Feb; 14(2):. doi:
10.1136/bcr-2021-241572. [PMID: 33637513] - Jaroslav Galba, Juraj Piešťanský, Andrej Kováč, Dominika Olešová, Ondrej Cehlár, Martin Kertys, Petr Kozlík, Petra Chaľová, Barbora Tirčová, Kristián Slíž, Peter Mikuš. Fast and Sensitive Screening of Oxandrolone and Its Major Metabolite 17-Epi-Oxandrolone in Human Urine by UHPLC-MS/MS with On-Line SPE Sample Pretreatment.
Molecules (Basel, Switzerland).
2021 Jan; 26(2):. doi:
10.3390/molecules26020480. [PMID: 33477515] - Akbar Ahmad, David N Herndon, Csaba Szabo. Oxandrolone protects against the development of multiorgan failure, modulates the systemic inflammatory response and promotes wound healing during burn injury.
Burns : journal of the International Society for Burn Injuries.
2019 05; 45(3):671-681. doi:
10.1016/j.burns.2018.10.006. [PMID: 31018913] - Shanlee M Davis, Najiba Lahlou, Matthew Cox-Martin, Karen Kowal, Philip S Zeitler, Judith L Ross. Oxandrolone Treatment Results in an Increased Risk of Gonadarche in Prepubertal Boys With Klinefelter Syndrome.
The Journal of clinical endocrinology and metabolism.
2018 09; 103(9):3449-3455. doi:
10.1210/jc.2018-00682. [PMID: 29931143] - Ashley N Guillory, David N Herndon, Michael B Silva, Clark R Andersen, Oscar E Suman, Celeste C Finnerty. Oxandrolone Coadministration Does Not Alter Plasma Propranolol Concentrations in Severely Burned Pediatric Patients.
Journal of burn care & research : official publication of the American Burn Association.
2017 Jul; 38(4):243-250. doi:
10.1097/bcr.0000000000000494. [PMID: 28240622] - S Rzeppa, L Viet. Analysis of sulfate metabolites of the doping agents oxandrolone and danazol using high performance liquid chromatography coupled to tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Sep; 1029-1030(?):1-9. doi:
10.1016/j.jchromb.2016.06.028. [PMID: 27394004] - Ahmed M Alkhunaizi, Mohamed A ElTigani, Rola S Rabah, Samih H Nasr. Acute bile nephropathy secondary to anabolic steroids.
Clinical nephrology.
2016 Feb; 85(2):121-6. doi:
10.5414/cn108696. [PMID: 26587777] - Matthew W Linakis, Chris Stockmann, Sarah C Campbell, Richard V Williams, Phillip T Burch, Linda M Lambert, Catherine M T Sherwin, Christopher A Reilly, Michael G Spigarelli. Quantitative Assay Validation for Oxandrolone in Human Plasma Using LC-MS-MS.
Journal of analytical toxicology.
2015 Sep; 39(7):526-31. doi:
10.1093/jat/bkv056. [PMID: 26017381] - Susan R Rose, Mi-Ok Kim, Leslie Korbee, Kimberly A Wilson, M Douglas Ris, Ori Eyal, Rosa Sherafat-Kazemzadeh, Sureka Bollepalli, Richard Harris, Michael R Jeng, David A Williams, Franklin O Smith. Oxandrolone for the treatment of bone marrow failure in Fanconi anemia.
Pediatric blood & cancer.
2014 Jan; 61(1):11-9. doi:
10.1002/pbc.24617. [PMID: 24019220] - S Guddat, G Fußhöller, S Beuck, A Thomas, H Geyer, A Rydevik, U Bondesson, M Hedeland, A Lagojda, W Schänzer, M Thevis. Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing.
Analytical and bioanalytical chemistry.
2013 Oct; 405(25):8285-94. doi:
10.1007/s00216-013-7218-1. [PMID: 23877183] - Konrad Bork. Current management options for hereditary angioedema.
Current allergy and asthma reports.
2012 Aug; 12(4):273-80. doi:
10.1007/s11882-012-0273-4. [PMID: 22729959] - Marc G Jeschke, Felicia N Williams, Celeste C Finnerty, Noe A Rodriguez, Gabriela A Kulp, Arny Ferrando, William B Norbury, Oscar E Suman, Robert Kraft, Ludwik K Branski, Ahmed M Al-mousawi, David N Herndon. The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes.
PloS one.
2012; 7(5):e35465. doi:
10.1371/journal.pone.0035465. [PMID: 22606232] - Jiyeol Yoon, Se Hoon Kim, Chang-Seok Ki, Min-Jung Kwon, Mie-Jin Lim, Seong-Ryul Kwon, Kowoon Joo, Chang-Gi Moon, Won Park. Carrier woman of Duchenne muscular dystrophy mimicking inflammatory myositis.
Journal of Korean medical science.
2011 Apr; 26(4):587-91. doi:
10.3346/jkms.2011.26.4.587. [PMID: 21468271] - Asja Stipić Marković, Martina Janzeković. [Increasing incidence of angioedema without urticaria--clinical features].
Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti.
2011; 65(2):119-27. doi:
. [PMID: 22359877] - Marc G Jeschke, Gerd G Gauglitz, Gabriela A Kulp, Celeste C Finnerty, Felicia N Williams, Robert Kraft, Oscar E Suman, Ronald P Mlcak, David N Herndon. Long-term persistance of the pathophysiologic response to severe burn injury.
PloS one.
2011; 6(7):e21245. doi:
10.1371/journal.pone.0021245. [PMID: 21789167] - Martha P D Zeger, Kavita Shah, Karen Kowal, Gordon B Cutler, Harvey Kushner, Judith L Ross. Prospective study confirms oxandrolone-associated improvement in height in growth hormone-treated adolescent girls with Turner syndrome.
Hormone research in paediatrics.
2011; 75(1):38-46. doi:
10.1159/000317529. [PMID: 20733274] - Monica Mazzarino, Sara Riggi, Xavier de la Torre, Francesco Botrè. Speeding up the process urine sample pre-treatment: some perspectives on the use of microwave assisted extraction in the anti-doping field.
Talanta.
2010 Jun; 81(4-5):1264-72. doi:
10.1016/j.talanta.2010.02.019. [PMID: 20441894] - Norleena P Gullett, Gautam Hebbar, Thomas R Ziegler. Update on clinical trials of growth factors and anabolic steroids in cachexia and wasting.
The American journal of clinical nutrition.
2010 Apr; 91(4):1143S-1147S. doi:
10.3945/ajcn.2010.28608e. [PMID: 20164318] - L S Halstead, S L Groah, A Libin, L F Hamm, L Priestley. The effects of an anabolic agent on body composition and pulmonary function in tetraplegia: a pilot study.
Spinal cord.
2010 Jan; 48(1):55-9. doi:
10.1038/sc.2009.82. [PMID: 19581914] - Hideo Sugita, Shin'ichi Takeda. Progress in muscular dystrophy research with special emphasis on gene therapy.
Proceedings of the Japan Academy. Series B, Physical and biological sciences.
2010; 86(7):748-56. doi:
10.2183/pjab.86.748. [PMID: 20689232] - M Iqbal Choudhary, Mohammad Yasin Mohammad, Syed Ghulam Musharraf, Masood Parvez, Amal Al-Aboudi, Atta-ur-Rahman. New oxandrolone derivatives by biotransformation using Rhizopus stolonifer.
Steroids.
2009 Nov; 74(13-14):1040-4. doi:
10.1016/j.steroids.2009.08.003. [PMID: 19698730] - Gloria Lena Vega, Fredrick L Dunn, Scott M Grundy. Impaired hepatic ketogenesis in moderately obese men with hypertriglyceridemia.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
2009 Apr; 57(4):590-4. doi:
10.2310/jim.0b013e31819e2f61. [PMID: 19342925] - Andrei S Chagin, Johanna Vannesjö, Lars Sävendahl. Androgen receptor modulation does not affect longitudinal growth of cultured fetal rat metatarsal bones.
Hormone research.
2009; 71(4):219-27. doi:
10.1159/000201111. [PMID: 19258714] - Gloria Lena Vega, Jacob J Clarenbach, Fredrick Dunn, Scott M Grundy. Oxandrolone enhances hepatic ketogenesis in adult men.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
2008 Oct; 56(7):920-4. doi:
10.2310/jim.0b013e318189153d. [PMID: 18797410] - James T Miller, Imad F Btaiche. Oxandrolone in pediatric patients with severe thermal burn injury.
The Annals of pharmacotherapy.
2008 Sep; 42(9):1310-5. doi:
10.1345/aph.1l162. [PMID: 18682543] - Aneta Gawlik, Ewa Malecka-Tendera. Hormonal therapy in a patient with a delayed diagnosis of Turner's syndrome.
Nature clinical practice. Endocrinology & metabolism.
2008 Mar; 4(3):173-7. doi:
10.1038/ncpendmet0747. [PMID: 18227816] - Marc G Jeschke, Celeste C Finnerty, Oscar E Suman, Gabriela Kulp, Ronald P Mlcak, David N Herndon. The effect of oxandrolone on the endocrinologic, inflammatory, and hypermetabolic responses during the acute phase postburn.
Annals of surgery.
2007 Sep; 246(3):351-60; discussion 360. doi:
10.1097/sla.0b013e318146980e. [PMID: 17717439] - Nicholas Namias. Advances in burn care.
Current opinion in critical care.
2007 Aug; 13(4):405-10. doi:
10.1097/mcc.0b013e328263888f. [PMID: 17599010] - Oscar J Pozo, Koen Deventer, Peter Van Eenoo, Frans T Delbeke. Presence of endogenous interferences in the urinary detection of selected anabolic steroids by liquid chromatography/electrospray tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2007; 21(17):2785-96. doi:
10.1002/rcm.3140. [PMID: 17661313] - Nighat N Kahn, Asru K Sinha, Ann M Spungen, William A Bauman. Effects of oxandrolone, an anabolic steroid, on hemostasis.
American journal of hematology.
2006 Feb; 81(2):95-100. doi:
10.1002/ajh.20532. [PMID: 16432848] - Rene Przkora, Marc G Jeschke, Robert E Barrow, Oscar E Suman, Walter J Meyer, Celeste C Finnerty, Arthur P Sanford, Jong Lee, David L Chinkes, Ronald P Mlcak, David N Herndon. Metabolic and hormonal changes of severely burned children receiving long-term oxandrolone treatment.
Annals of surgery.
2005 Sep; 242(3):384-9, discussion 390. doi:
10.1097/01.sla.0000180398.70103.24. [PMID: 16135924] - Nola H Yu, Emmie N M Ho, David K K Leung, Terence S M Wan. Screening of anabolic steroids in horse urine by liquid chromatography-tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2005 Apr; 37(5):1031-8. doi:
10.1016/j.jpba.2004.08.041. [PMID: 15862683] - Zvi Zadik, Tali Sinai, Amnon Zung, Ram Reifen. Longitudinal monitoring of bone measured by quantitative multisite ultrasound in patients with Crohn's disease.
Journal of clinical gastroenterology.
2005 Feb; 39(2):120-3. doi:
NULL. [PMID: 15681906] - E Todd Schroeder, Ling Zheng, Michelle D Ong, Carmen Martinez, Carla Flores, Yolanda Stewart, Colleen Azen, Fred R Sattler. Effects of androgen therapy on adipose tissue and metabolism in older men.
The Journal of clinical endocrinology and metabolism.
2004 Oct; 89(10):4863-72. doi:
10.1210/jc.2004-0784. [PMID: 15472177] - Kevin D Murphy, Suchmor Thomas, Ronald P Mlcak, David L Chinkes, Gordon L Klein, David N Herndon. Effects of long-term oxandrolone administration in severely burned children.
Surgery.
2004 Aug; 136(2):219-24. doi:
10.1016/j.surg.2004.04.022. [PMID: 15300183] - Kélem de Nardi Chagas, Viviana Galimbert Arruk, Maria Elisa Bertocco Andrade, Dewton de Moraes Vasconcelos, Michael Kirschfink, Alberto José da Silva Duarte, Anete Sevciovic Grumach. [Therapeutic approach of hereditary angioedema].
Revista da Associacao Medica Brasileira (1992).
2004 Jul; 50(3):314-9. doi:
10.1590/s0104-42302004000300041. [PMID: 15499486] - Z Zadik, T Sinai, A Zung, R Reifen. Vitamin A and iron supplementation is as efficient as hormonal therapy in constitutionally delayed children.
Clinical endocrinology.
2004 Jun; 60(6):682-7. doi:
10.1111/j.1365-2265.2004.02034.x. [PMID: 15163330] - Michele M Gottschlich, Theresa Mayes, Jane Khoury, Glenn D Warden. Hypovitaminosis D in acutely injured pediatric burn patients.
Journal of the American Dietetic Association.
2004 Jun; 104(6):931-41, quiz 1031. doi:
10.1016/j.jada.2004.03.020. [PMID: 15175591] - Joseph A Church. Oxandrolone treatment of childhood hereditary angioedema.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2004 Mar; 92(3):377-8. doi:
10.1016/s1081-1206(10)61578-5. [PMID: 15049404] - Antti Leinonen, Tiia Kuuranne, Tapio Kotiaho, Risto Kostiainen. Screening of free 17-alkyl-substituted anabolic steroids in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry.
Steroids.
2004 Feb; 69(2):101-9. doi:
10.1016/j.steroids.2003.10.007. [PMID: 15013688] - Meir Lampit, Ze'ev Hochberg. Androgen therapy in constitutional delay of growth.
Hormone research.
2003; 59(6):270-5. doi:
10.1159/000070624. [PMID: 12784090] - J M Gervasio, R N Dickerson, J Swearingen, M E Yates, C Yuen, T C Fabian, M A Croce, R O Brown. Oxandrolone in trauma patients.
Pharmacotherapy.
2000 Nov; 20(11):1328-34. doi:
10.1592/phco.20.17.1328.34889. [PMID: 11079282] - N C Nathwani, R Unwin, C G Brook, P C Hindmarsh. The influence of renal and cardiovascular abnormalities on blood pressure in Turner syndrome.
Clinical endocrinology.
2000 Mar; 52(3):371-7. doi:
10.1046/j.1365-2265.2000.00961.x. [PMID: 10718836] - A M Spungen, D R Grimm, M Strakhan, P M Pizzolato, W A Bauman. Treatment with an anabolic agent is associated with improvement in respiratory function in persons with tetraplegia: a pilot study.
The Mount Sinai journal of medicine, New York.
1999 May; 66(3):201-5. doi:
NULL. [PMID: 10377553] - U Querfeld, S Döpper, A Gradehand, P Kiencke, F Wahn, H J Zeisel. Long-term treatment with growth hormone has no persisting effect on lipoprotein(a) in patients with Turner's syndrome.
The Journal of clinical endocrinology and metabolism.
1999 Mar; 84(3):967-70. doi:
10.1210/jcem.84.3.5516. [PMID: 10084580] - E Vazquez. Comparing Oxandrin and Anadrol-50.
Positively aware : the monthly journal of the Test Positive Aware Network.
1998 Jul; 9(4):49-51. doi:
. [PMID: 11365632] - N C Nathwani, P C Hindmarsh, A A Massarano, C G Brook. Gonadotrophin pulsatility in girls with the Turner syndrome: modulation by exogenous sex steroids.
Clinical endocrinology.
1998 Jul; 49(1):107-13. doi:
10.1046/j.1365-2265.1998.00495.x. [PMID: 9797854] - G Haeusler, K Schmitt, P Blümel, E Plöchl, T Waldhör, H Frisch. Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone.
The Journal of clinical endocrinology and metabolism.
1996 Feb; 81(2):536-41. doi:
10.1210/jcem.81.2.8636264. [PMID: 8636264] - J C Lovejoy, G A Bray, C S Greeson, M Klemperer, J Morris, C Partington, R Tulley. Oral anabolic steroid treatment, but not parenteral androgen treatment, decreases abdominal fat in obese, older men.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
1995 Sep; 19(9):614-24. doi:
. [PMID: 8574271] - S D Frasier, B M Lippe. Short stature.
Current therapy in endocrinology and metabolism.
1994; 5(?):60-3. doi:
NULL. [PMID: 7704803] - G P Gubbins, T E Moritz, L S Marsano, R Talwalkar, C J McClain, C L Mendenhall. Helicobacter pylori is a risk factor for hepatic encephalopathy in acute alcoholic hepatitis: the ammonia hypothesis revisited. The Veterans Administration Cooperative Study Group No. 275.
The American journal of gastroenterology.
1993 Nov; 88(11):1906-10. doi:
NULL. [PMID: 8237940] - A Malhotra, E Poon, W Y Tse, P J Pringle, P C Hindmarsh, C G Brook. The effects of oxandrolone on the growth hormone and gonadal axes in boys with constitutional delay of growth and puberty.
Clinical endocrinology.
1993 Apr; 38(4):393-8. doi:
10.1111/j.1365-2265.1993.tb00520.x. [PMID: 8319371] - F C Wu, D C Brown, G E Butler, H F Stirling, C J Kelnar. Early morning plasma testosterone is an accurate predictor of imminent pubertal development in prepubertal boys.
The Journal of clinical endocrinology and metabolism.
1993 Jan; 76(1):26-31. doi:
10.1210/jcem.76.1.8421096. [PMID: 8421096] - H Bi, R Massé. Studies on anabolic steroids--12. Epimerization and degradation of anabolic 17 beta-sulfate-17 alpha-methyl steroids in human: qualitative and quantitative GC/MS analysis.
The Journal of steroid biochemistry and molecular biology.
1992 Jun; 42(5):533-46. doi:
10.1016/0960-0760(92)90267-m. [PMID: 1616883] - G Haeusler, H Frisch. Growth hormone treatment in Turner's syndrome: short and long-term effects on metabolic parameters.
Clinical endocrinology.
1992 Mar; 36(3):247-53. doi:
10.1111/j.1365-2265.1992.tb01440.x. [PMID: 1563078] - B H Grokett, N Ahmad, D W Warren. The effects of an anabolic steroid (oxandrolone) on reproductive development in the male rat.
Acta endocrinologica.
1992 Feb; 126(2):173-8. doi:
10.1530/acta.0.1260173. [PMID: 1543024] - S Loche, C Pintor, P Cambiaso, A Lampis, D Carta, R Corda, M Cappa. The effect of short-term growth hormone or low-dose oxandrolone treatment in boys with constitutional growth delay.
Journal of endocrinological investigation.
1991 Oct; 14(9):747-50. doi:
10.1007/bf03347908. [PMID: 1761810] - H L Bonkovsky, D A Fiellin, G S Smith, D P Slaker, D Simon, J T Galambos. A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. I. Short-term effects on liver function.
The American journal of gastroenterology.
1991 Sep; 86(9):1200-8. doi:
. [PMID: 1909085] - H L Bonkovsky, R H Singh, I H Jafri, D A Fiellin, G S Smith, D Simon, G A Cotsonis, D P Slaker. A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition.
The American journal of gastroenterology.
1991 Sep; 86(9):1209-18. doi:
. [PMID: 1909086] - L Rees, S P Rigden, C Chantler. The influence of steroid therapy and recombinant human erythropoietin on the growth of children with renal disease.
Pediatric nephrology (Berlin, Germany).
1991 Jul; 5(4):556-8. doi:
10.1007/bf01453701. [PMID: 1911137] - A Ulloa-Aguirre, R M Blizzard, E Garcia-Rubi, A D Rogol, K Link, C M Christie, M L Johnson, J D Veldhuis. Testosterone and oxandrolone, a nonaromatizable androgen, specifically amplify the mass and rate of growth hormone (GH) secreted per burst without altering GH secretory burst duration or frequency or the GH half-life.
The Journal of clinical endocrinology and metabolism.
1990 Oct; 71(4):846-54. doi:
10.1210/jcem-71-4-846. [PMID: 2401714] - C L Mendenhall, C J Grossman, G A Roselle, Z Hertelendy, S J Ghosn, K Lamping, K Martin. Anabolic steroid effects on immune function: differences between analogues.
The Journal of steroid biochemistry and molecular biology.
1990 Sep; 37(1):71-6. doi:
10.1016/0960-0760(90)90374-t. [PMID: 2242353] - L Rees, S A Greene, S P Rigden, G B Haycock, C Chantler, M A Preece. Oxandrolone for delayed puberty in boys taking long-term steroid therapy for renal disease.
Pediatric nephrology (Berlin, Germany).
1990 Mar; 4(2):160-2. doi:
10.1007/bf00858829. [PMID: 2397183] - R Massé, H G Bi, C Ayotte, R Dugal. Studies on anabolic steroids. II--Gas chromatographic/mass spectrometric characterization of oxandrolone urinary metabolites in man.
Biomedical & environmental mass spectrometry.
1989 Jun; 18(6):429-38. doi:
10.1002/bms.1200180612. [PMID: 2765703] - R Stanhope, C R Buchanan, G C Fenn, M A Preece. Double blind placebo controlled trial of low dose oxandrolone in the treatment of boys with constitutional delay of growth and puberty.
Archives of disease in childhood.
1988 May; 63(5):501-5. doi:
10.1136/adc.63.5.501. [PMID: 3389864] - D M Wilson, J W Frane, B Sherman, A J Johanson, R L Hintz, R G Rosenfeld. Carbohydrate and lipid metabolism in Turner syndrome: effect of therapy with growth hormone, oxandrolone, and a combination of both.
The Journal of pediatrics.
1988 Feb; 112(2):210-7. doi:
10.1016/s0022-3476(88)80057-x. [PMID: 3276862] - R G Rosenfeld, R L Hintz, A J Johanson, B Sherman. Results from the first 2 years of a clinical trial with recombinant DNA-derived human growth hormone (somatrem) in Turner's syndrome.
Acta paediatrica Scandinavica. Supplement.
1987; 331(?):59-69. doi:
10.1111/j.1651-2227.1987.tb17100.x. [PMID: 3300157] - S Loche, R Corda, A Lampis, R Puggioni, S G Cella, E E Muller, C Pintor. The effect of oxandrolone on the growth hormone response to growth hormone releasing hormone in children with constitutional growth delay.
Clinical endocrinology.
1986 Aug; 25(2):195-200. doi:
10.1111/j.1365-2265.1986.tb01682.x. [PMID: 3098462] - K Link, R M Blizzard, W S Evans, D L Kaiser, M W Parker, A D Rogol. The effect of androgens on the pulsatile release and the twenty-four-hour mean concentration of growth hormone in peripubertal males.
The Journal of clinical endocrinology and metabolism.
1986 Jan; 62(1):159-64. doi:
10.1210/jcem-62-1-159. [PMID: 3940264] - W R Hazzard, P W Wahl, C Gagne, D Applebaum-Bowden, G R Warnick, J J Albers. Plasma and lipoprotein lipid responses to four hypolipid drugs.
Lipids.
1984 Feb; 19(2):73-9. doi:
10.1007/bf02534494. [PMID: 6708754] - B R Krause, A D Hartman. Accumulation of adipocyte cholesterol during hypolipidemic drug treatment in cholesterol-fed rats.
Biochimica et biophysica acta.
1982 Dec; 713(3):485-93. doi:
10.1016/0005-2760(82)90308-3. [PMID: 7150624] - W Schönberger, P Benes, B Morsches, B Zabel, E Scheidt. [Improvement in the longitudinal growth in Ullrich-Turner syndrome with oxandrolone. Function of urinary excretion of steroid hormones].
Deutsche medizinische Wochenschrift (1946).
1982 Jul; 107(26):1008-11. doi:
10.1055/s-2008-1070063. [PMID: 6211346] - T Hara, J P Miller, A M Gotto, J R Patsch. Oxandrolone and plasma triglyceride reduction: effect on triglyceride-rich and high density lipoproteins.
Artery.
1981; 9(5):328-41. doi:
. [PMID: 7316782] - R W Jones, M M El Bishti, S R Bloom, J Burke, J E Carter, R Counahan, R N Dalton, M C Morris, C Chantler. The effects of anabolic steroids on growth, body composition, and metabolism in boys with chronic renal failure on regular hemodialysis.
The Journal of pediatrics.
1980 Oct; 97(4):559-66. doi:
10.1016/s0022-3476(80)80009-6. [PMID: 7420218] - J M de Olivera. [Effect of oxandrolone on lipid metabolism and its influence on the atheromatous process: experiments in animals].
Arquivos brasileiros de cardiologia.
1980 Apr; 34(4):285-8. doi:
". [PMID: 7436786] - R C Franklin, G C Rennie, H G Burger, D P Cameron. Endocrine influences on serum acid-ethanol soluble non-suppressible in insulin-like activity (NSILA-S).
Clinical endocrinology.
1980 Feb; 12(2):127-36. doi:
10.1111/j.1365-2265.1980.tb02127.x. [PMID: 6772355] - M W Freeman, E Spring-Mills, A L Jones. The effect of oxandrolone on low and high density lipoprotein profiles in retired breeder rats.
Journal of gerontology.
1980 Jan; 35(1):31-8. doi:
10.1093/geronj/35.1.31. [PMID: 7350219] - N J Hopwood, R P Kelch, W B Zipf, R J Hernandez. The effect of synthetic androgens on the hypothalamic-pituitary-gonadal axis in boys with constitutionally delayed growth.
The Journal of pediatrics.
1979 Apr; 94(4):657-62. doi:
10.1016/s0022-3476(79)80046-3. [PMID: 372514] - T Tamai, T Nakai, S Yamada, T Kobayashi, T Hayashi, Y Kutsumi, R Takeda. Effects of oxandrolone on plasma lipoproteins in patients with type IIa, IIb and IV hyperlipoproteinemia: occurrence of hypo-high density lipoproteinemia.
Artery.
1979 Feb; 5(2):125-43. doi:
. [PMID: 231951] - A Aynsley-Green, M Zachmann, E A Werder, R Illig, A Prader. Endocrine studies in Fanconi's anaemia. Report of 4 cases.
Archives of disease in childhood.
1978 Feb; 53(2):126-31. doi:
10.1136/adc.53.2.126. [PMID: 25628] - C L Malmendier, C J van den Bergen, G Emplit, C Delcroix. A long-term study of the efficacy of oxandrolone in hyperlipoproteinemias.
Journal of clinical pharmacology.
1978 Jan; 18(1):42-53. doi:
10.1002/j.1552-4604.1978.tb01559.x. [PMID: 338645] - R S Lees, A M Lees. Therapy of the hyperlipidemias.
Postgraduate medicine.
1976 Sep; 60(3):99-107. doi:
10.1080/00325481.1976.11712083. [PMID: 959087] - C J Glueck, P Gartside, R W Fallat, S Mendoza. Effect of sex hormones on protamine inactivated and resistant postheparin plasma lipases.
Metabolism: clinical and experimental.
1976 Jun; 25(6):625-32. doi:
10.1016/0026-0495(76)90059-7. [PMID: 178980] - L Rivera-Calimlim, H Nasrallah, J Strauss, L Lasagna. Clinical response and plasma levels: effect of dose, dosage schedules, and drug interactions on plasma chlorpromazine levels.
The American journal of psychiatry.
1976 Jun; 133(6):646-52. doi:
10.1176/ajp.133.6.646. [PMID: 5901] - D Kritchevsky, S A Tepper, J A Story. Influence of four agents (tibric acid, DH 990, oxandrolone and Sch 9122) on aspects of lipid metabolism in rats).
Arzneimittel-Forschung.
1976; 26(5):862-4. doi:
NULL. [PMID: 989359] - G J Schapel, K D Edwards. Efficacy and interactions of oxandrolone, halo-fenate and clofibrate in a factorial study on experimental acute nephrotic hyperlipidemia.
The Journal of pharmacology and experimental therapeutics.
1975 Jul; 194(1):274-84. doi:
. [PMID: 1171221] - C Ehnholm, J K Huttunen, P J Kinnunen, T A Miettinen, E A Nikkilä. Effect of oxandrolone treatment on the activity of lipoprotein lipase, hepatic lipase and phospholipase A1 of human postheparin plasma.
The New England journal of medicine.
1975 Jun; 292(25):1314-7. doi:
10.1056/nejm197506192922503. [PMID: 1128607] - P A Lee, A Kowarski, C J Migeon, R M Blizzard. Lack of correlation between gonadotropin and adrenal androgen levels in agonadal children.
The Journal of clinical endocrinology and metabolism.
1975 Apr; 40(4):664-9. doi:
10.1210/jcem-40-4-664. [PMID: 165213] - D L Schmucker, A L Jones. Hepatic fine structure in young and aging rats treated with oxandrolone: a morphometric study.
Journal of lipid research.
1975 Mar; 16(2):143-50. doi:
. [PMID: 1127354] - M Saeed uz Zafar, R C Mellinger, C Wolf, L B Morrow, C Whitten, D DeJongh, E Hills. Nitrogen metabolism in growth hormone-deficient children receiving oxandrolone and human growth hormone.
Metabolism: clinical and experimental.
1974 Mar; 23(3):239-47. doi:
10.1016/0026-0495(74)90062-6. [PMID: 4591987] - A G Olsson, L Orö, S Rössner. Effects of oxandrolone on plasma lipoproteins and the intravenous fat tolerance in man.
Atherosclerosis.
1974 Mar; 19(2):337-46. doi:
10.1016/0021-9150(74)90068-9. [PMID: 4360244] - E S Mills, B M Kriz, A L Jones. Reduction of plasma cholesterol levels in male retired breeder rats by an anabolic steroid, oxandrolone.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1973 Dec; 144(3):861-3. doi:
10.3181/00379727-144-37698. [PMID: 4765965] - O H Bolch, J C Warren. Induction of premature menstruation with anabolic steroids.
American journal of obstetrics and gynecology.
1973 Sep; 117(1):121-5. doi:
10.1016/0002-9378(73)90738-2. [PMID: 4722368] - E Zorrilla, C Magos, P A Serrano. [Effect of oxandrolone on the serum lipids in type IV and IIb hyperlipidemia].
Archivos del Instituto de Cardiologia de Mexico.
1973 Mar; 43(2):270-8. doi:
. [PMID: 4712792] - A G Goldman, Z Zarday. Effects of oxandrolone in advanced renal insufficiency. Report of metabolic balance studies.
New York state journal of medicine.
1973 Jan; 73(2):316-9. doi:
NULL. [PMID: 4509855] - C Sirtori, R Fumagalli, R Paoletti. Hypolipidemic drugs.
Advances in experimental medicine and biology.
1973; 38(?):171-98. doi:
". [PMID: 4594063] - S Rössner. The intravenous fat tolerance test with intralipid in various types of hyperlipidaemias and comparison between metabolism of intralipid and VLDL.
Advances in experimental medicine and biology.
1973; 38(?):69-85. doi:
". [PMID: 4358294]