pentobarbital (BioDeep_00000408809)
Main id: BioDeep_00000002742
代谢物信息卡片
pentobarbital
化学式: C11H18N2O3 (226.1317358)
中文名称: 戊巴比妥
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC(C)C(CC)(C(=O)1)C(=O)N=C(O)N1
InChI: InChI=1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CA - Barbiturates, plain
C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C67084 - Barbiturate
D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators
同义名列表
3 个代谢物同义名
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chang-Lei Li, Xiao-Qing Chen, Hui-Ling Yi, Bao-Miao Ma. Effect of Repeated Application of Flos Daturae on Sedative and Hypnotic in Mice.
Studies in health technology and informatics.
2023 Nov; 308(?):42-47. doi:
10.3233/shti230822. [PMID: 38007723] - J W Walker, B M Shoemake, D G Quadros, J W Thorne, N C Cahill. Selecting goats for juniper consumption did not improve their liver Phase I detoxification.
Journal of animal science.
2023 Jun; ?(?):. doi:
10.1093/jas/skad180. [PMID: 37328163] - Chun Woong Park, Ki-Bae Hong, Hyung Joo Suh, Yejin Ahn. Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors.
Journal of food and drug analysis.
2023 Jun; 31(2):278-288. doi:
10.38212/2224-6614.3456. [PMID: 37335157] - Kei Kawada, Tomoaki Ishida, Kohei Jobu, Shumpei Morisawa, Motoki Nishida, Naohisa Tamura, Saburo Yoshioka, Mitsuhiko Miyamura. Glycyrrhizae Radix suppresses lipopolysaccharide- and diazepam-induced nerve inflammation in the hippocampus, and contracts the duration of pentobarbital- induced loss of righting reflex in a mouse model.
Journal of natural medicines.
2023 Apr; ?(?):. doi:
10.1007/s11418-023-01700-2. [PMID: 37115471] - Keman Mu, Jian Zhang, Xinqian Feng, Di Zhang, Kangning Li, Rui Li, Peng Yang, Shengjun Mao. Sedative-hypnotic effects of Boropinol-B on mice via activation of GABAA receptors.
The Journal of pharmacy and pharmacology.
2023 Jan; 75(1):57-65. doi:
10.1093/jpp/rgac077. [PMID: 36385301] - Shana Wuken, Junjun Li, Xiaoli Gao, Shungang Jiao, Xiaojing Ma, Suyile Chen, Pengfei Tu, Luqi Huang, Xingyun Chai. Zerumbone, a major sesquiterpene from Syringa pinnatifolia Hemsl., exerts the sedative effect by regulating GABAergic nervous system.
Journal of ethnopharmacology.
2023 Jan; 301(?):115813. doi:
10.1016/j.jep.2022.115813. [PMID: 36220513] - María de la Cabeza Fernández, Marta Sánchez, Armando Caceres, Irene Iglesias, Maria Pilar Gómez-Serranillos. Neuropharmacological Effects in Animal Models and HPLC-Phytochemical Profiling of Byrsonima crassifolia (L.) Kunth Bark Extracts.
Molecules (Basel, Switzerland).
2023 Jan; 28(2):. doi:
10.3390/molecules28020764. [PMID: 36677821] - Luo-Xuan Wang, Qian Zhao, Yang Zhang, Rui Xue, Shuo Li, Ying Li, Ji-Jun Yu, Jing-Cao Li, You-Zhi Zhang. Network pharmacology and pharmacological evaluation for deciphering novel indication of Sishen Wan in insomnia treatment.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Jan; 108(?):154500. doi:
10.1016/j.phymed.2022.154500. [PMID: 36288650] - Wei-Liang Liu, Bai-Fen Wu, Jian-Hua Shang, Xue-Feng Wang, Yun-Li Zhao, Ai-Xiang Huang. Moringa oleifera seed ethanol extract and its active component kaempferol potentiate pentobarbital-induced sleeping behaviours in mice via a GABAergic mechanism.
Pharmaceutical biology.
2022 Dec; 60(1):810-824. doi:
10.1080/13880209.2022.2056207. [PMID: 35587996] - Misato Ota, Yasuhito Maki, Ling-Yu Xu, Toshiaki Makino. Prolonging effects of Valeriana fauriei root extract on pentobarbital-induced sleep in caffeine-induced insomnia model mice and the pharmacokinetics of its active ingredients under conditions of glycerol fatty acid ester as emulsifiers.
Journal of ethnopharmacology.
2022 Nov; 298(?):115625. doi:
10.1016/j.jep.2022.115625. [PMID: 35970315] - Duhyeon Kim, Minseok Yoon, Seonghui Kim, Min Young Um, Suengmok Cho. Effects of Green Kiwifruit Peel Extract on Sleep-Wake Profiles in Mice: A Polysomnographic Study Based on Electroencephalogram and Electromyogram Recordings.
Nutrients.
2022 Nov; 14(22):. doi:
10.3390/nu14224732. [PMID: 36432419] - Meng-Xuan Gui, Bin Huang, Jun Peng, Xi Chen, Ragunath Muthu, Ying Gao, Rui-Guo Wang, Jiu-Mao Lin. Babao Dan Alleviates 5-Fluorouracil-Induced Intestinal Damage via Wnt/β-Catenin Pathway.
Chinese journal of integrative medicine.
2022 Nov; 28(11):1000-1006. doi:
10.1007/s11655-021-3282-0. [PMID: 33420580] - Jidong Zhou, Hang Li, Liying Xun, Lei Wang, Qitao Zhao. Hyperlipidemia attenuates the mobilization of endothelial progenitor cells induced by acute myocardial ischemia via VEGF/eNOS/NO/MMP-9 pathway.
Aging.
2022 10; 14(19):7877-7889. doi:
10.18632/aging.204314. [PMID: 36202115] - Huan-Hua Xu, Liang Yang, Ming-Xia Tang, An-Ping Ye, Bo-Dan Tu, Zhen-Hong Jiang, Jian-Feng Yi. From cis-Lobeline to trans-Lobeline: Study on the Pharmacodynamics and Isomerization Factors.
Molecules (Basel, Switzerland).
2022 Sep; 27(19):. doi:
10.3390/molecules27196253. [PMID: 36234790] - Xiaoyu Gu, Xuelin Zhao, Zhihao Mao, Yan Shi, Meng Xu, Maolin Cai, Fei Xie. Effect of different anesthetic dose of pentobarbital on respiratory activity in rabbits.
Computers in biology and medicine.
2022 06; 145(?):105501. doi:
10.1016/j.compbiomed.2022.105501. [PMID: 35417816] - Kei Kawada, Tomoaki Ishida, Kohei Jobu, Shumpei Morisawa, Tetsushi Kawazoe, Motoki Nishida, Satomi Nishimura, Naohisa Tamura, Saburo Yoshioka, Mitsuhiko Miyamura. Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital.
Journal of natural medicines.
2022 Jun; 76(3):634-644. doi:
10.1007/s11418-022-01612-7. [PMID: 35257304] - Minseok Yoon, Jonghoon Jung, Minjung Kim, Changho Lee, Suengmok Cho, Minyoung Um. Effect of Black Pepper (Piper nigrum) Extract on Caffeine-Induced Sleep Disruption and Excitation in Mice.
Nutrients.
2022 May; 14(11):. doi:
10.3390/nu14112249. [PMID: 35684048] - Adam W Stern, Manavi Muralidhar, Cynthia Cole. Evaluation of a human urine barbiturate test to screen for pentobarbital euthanasia of dogs and cats.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2022 Mar; 34(2):226-230. doi:
10.1177/10406387211070539. [PMID: 35012382] - Mohammad-Ali Sobhanifar, Roghayeh Rashidi, Arezoo Rajabian, Fatemeh Forouzanfar, Maede Hasanpour, Mehrdad Iranshahi, Hassan Rakhshandeh, Azar Hosseini. The possible mechanism of Datura stramonium on pentobarbital-induced sleep in mice.
The International journal of neuroscience.
2022 Feb; ?(?):1-9. doi:
10.1080/00207454.2021.1998045. [PMID: 35213269] - Yu Ri Kim, Sun Young Lee, So Min Lee, Insop Shim, Mi Young Lee. Effect of Hibiscus syriacus Linnaeus extract and its active constituent, saponarin, in animal models of stress-induced sleep disturbances and pentobarbital-induced sleep.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Feb; 146(?):112301. doi:
10.1016/j.biopha.2021.112301. [PMID: 34915415] - Li Han, Aimei Chen, Ling Liu, Fang Wang. Leonurine Preconditioning Attenuates Ischemic Acute Kidney Injury in Rats by Promoting Nrf2 Nuclear Translocation and Suppressing TLR4/NF-κB Pathway.
Chemical & pharmaceutical bulletin.
2022; 70(1):66-73. doi:
10.1248/cpb.c21-00740. [PMID: 34980736] - Kathleen A Cooney, Jennifer A Coates, Lesley M Leach, Kristin R Hrenchir, Lori R Kogan. The use of intrarenal injection of sodium pentobarbital for euthanasia in cats.
American journal of veterinary research.
2021 Nov; 83(1):95-99. doi:
10.2460/ajvr.21.08.0123. [PMID: 34757922] - Duhyeon Kim, Jinsoo Kim, Seonghui Kim, Minseok Yoon, Minyoung Um, Dongmin Kim, Sangoh Kwon, Suengmok Cho. Arousal-Inducing Effect of Garcinia cambogia Peel Extract in Pentobarbital-Induced Sleep Test and Electroencephalographic Analysis.
Nutrients.
2021 Aug; 13(8):. doi:
10.3390/nu13082845. [PMID: 34445005] - Oswaldo Frausto-González, Claudia J Bautista, Fernando Narváez-González, Alberto Hernandez-Leon, Erika Estrada-Camarena, Fausto Rivero-Cruz, María Eva González-Trujano. Bertholletia excelsa Seeds Reduce Anxiety-Like Behavior, Lipids, and Overweight in Mice.
Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
10.3390/molecules26113212. [PMID: 34072024] - Harriet Lea-Banks, Ying Meng, Sheng-Kai Wu, Rania Belhadjhamida, Clement Hamani, Kullervo Hynynen. Ultrasound-sensitive nanodroplets achieve targeted neuromodulation.
Journal of controlled release : official journal of the Controlled Release Society.
2021 04; 332(?):30-39. doi:
10.1016/j.jconrel.2021.02.010. [PMID: 33600879] - A-Hyun Jeong, Jisu Hwang, Kyungae Jo, Singeun Kim, Yejin Ahn, Hyung Joo Suh, Hyeon-Son Choi. Fermented Gamma Aminobutyric Acid Improves Sleep Behaviors in Fruit Flies and Rodent Models.
International journal of molecular sciences.
2021 Mar; 22(7):. doi:
10.3390/ijms22073537. [PMID: 33805468] - Mohammad Madadzadeh, Mehdi Abbasnejad, Mahtab Mollashahi, Ali Mohammad Pourrahimi, Saeed Esmaeili-Mahani. Phytohormone abscisic acid boosts pentobarbital-induced sleep through activation of GABA-A, PPARβ and PPARγ receptor signaling.
Arquivos de neuro-psiquiatria.
2021 03; 79(3):216-221. doi:
10.1590/0004-282x-anp-2019-0393. [PMID: 33886795] - Lucas W Smedley, Denise Rios, Colleen A Barthol, Rachel E Garvin. Iatrogenic Propylene Glycol Intoxication Due to High-Dose Pentobarbital for Refractory Intracranial Hypertension: A Case Report.
Journal of pharmacy practice.
2020 Dec; 33(6):895-898. doi:
10.1177/0897190019854575. [PMID: 31238770] - Nan Zhang, Mu Luo, Lei He, Lei Yao. Chemical Composition of Essential Oil from Flower of 'Shanzhizi' (Gardenia jasminoides Ellis) and Involvement of Serotonergic System in Its Anxiolytic Effect.
Molecules (Basel, Switzerland).
2020 Oct; 25(20):. doi:
10.3390/molecules25204702. [PMID: 33066512] - Yang Zou, Qiming Liu, Piaoting Guo, Yang Huang, Zhengcong Ye, Jiong Hu. Anti‑chondrocyte apoptosis effect of genistein in treating inflammation‑induced osteoarthritis.
Molecular medicine reports.
2020 09; 22(3):2032-2042. doi:
10.3892/mmr.2020.11254. [PMID: 32582961] - Chun-Yan Shen, Lin Wan, Jing-Jing Zhu, Jian-Guo Jiang. Targets and underlying mechanisms related to the sedative and hypnotic activities of saponin extracts from semen Ziziphus jujube.
Food & function.
2020 May; 11(5):3895-3903. doi:
10.1039/d0fo00098a. [PMID: 32407431] - Wei-Liang Liu, Bai-Fen Wu, Jian-Hua Shang, Yun-Li Zhao, Ai-Xiang Huang. Moringa oleifera Lam Seed Oil Augments Pentobarbital-Induced Sleeping Behaviors in Mice via GABAergic Systems.
Journal of agricultural and food chemistry.
2020 Mar; 68(10):3149-3162. doi:
10.1021/acs.jafc.0c00037. [PMID: 32062961] - Ayman S Mohamed, Mohamed Hosney, Heba Bassiony, Sarah S Hassanein, Amel M Soliman, Sohair R Fahmy, Khadiga Gaafar. Sodium pentobarbital dosages for exsanguination affect biochemical, molecular and histological measurements in rats.
Scientific reports.
2020 01; 10(1):378. doi:
10.1038/s41598-019-57252-7. [PMID: 31942001] - Fatemeh Forouzanfar, Mohammad M Vahedi, Azita Aghaei, Hassan Rakhshandeh. Hydroalcoholic Extract of Cuscuta Epithymum Enhances Pentobarbitalinduced Sleep: Possible Involvement of GABAergic System.
Current drug discovery technologies.
2020; 17(3):332-337. doi:
10.2174/1570163815666181105091801. [PMID: 30394211] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Laura E Burns, David J Borts. Rapid untargeted screening for drug residues in animal tissues with liquid microjunction surface sampling probe mass spectrometry.
Analytica chimica acta.
2019 Jul; 1063(?):75-81. doi:
10.1016/j.aca.2019.01.029. [PMID: 30967188] - Stephanie M Wolahan, Elliott Lebby, Howard C Mao, David McArthur, Courtney Real, Paul Vespa, Daniel Braas, Thomas C Glenn. Novel Metabolomic Comparison of Arterial and Jugular Venous Blood in Severe Adult Traumatic Brain Injury Patients and the Impact of Pentobarbital Infusion.
Journal of neurotrauma.
2019 01; 36(2):212-221. doi:
10.1089/neu.2018.5674. [PMID: 29901425] - Shokouhsadat Hamedi, Fatemeh Forouzanfar, Hassan Rakhshandeh, Amirali Arian. Hypnotic Effect of Portulaca oleracea on Pentobarbital-Induced Sleep in Mice.
Current drug discovery technologies.
2019; 16(2):198-203. doi:
10.2174/1570163815666180308142543. [PMID: 29521239] - Igor Maksimovic, Song Zhang, Ivan Vuckovic, Maria V Irazabal. Kidney harvesting and metabolite extraction for metabolomics studies in rodents.
Methods in cell biology.
2019; 154(?):15-29. doi:
10.1016/bs.mcb.2019.05.009. [PMID: 31493816] - Dino F Druda, Santosh Gone, Andis Graudins. Deliberate Self-poisoning with a Lethal Dose of Pentobarbital with Confirmatory Serum Drug Concentrations: Survival After Cardiac Arrest with Supportive Care.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2019 Jan; 15(1):45-48. doi:
10.1007/s13181-018-0675-3. [PMID: 30073621] - David M Hensler, Deepika P McConnell, Kimberly E Levasseur-Franklin, Kasey M Greathouse. Pentobarbital Removal During Continuous Venovenous Hemofiltration: Case Report and Review of the Literature.
Journal of pharmacy practice.
2018 Dec; 31(6):682-686. doi:
10.1177/0897190017743130. [PMID: 29162023] - Vafa Baradaran Rahimi, Vahid Reza Askari, Amineh Sadat Tajani, Azar Hosseini, Hassan Rakhshandeh. Evaluation of the Sleep-Prolonging Effect of Lagenaria vulgaris and Cucurbita pepo Extracts on Pentobarbital-Induced Sleep and Possible Mechanisms of Action.
Medicina (Kaunas, Lithuania).
2018 Jul; 54(4):. doi:
10.3390/medicina54040055. [PMID: 30344286] - Hiroaki Takemoto, Jun Takahashi, Sumiko Hyuga, Hiroshi Odaguchi, Nahoko Uchiyama, Takuro Maruyama, Tadatoshi Yamashita, Masashi Hyuga, Naohiro Oshima, Yoshiaki Amakura, Takashi Hakamatsuka, Yukihiro Goda, Toshihiko Hanawa, Yoshinori Kobayashi. Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.
Biological & pharmaceutical bulletin.
2018; 41(2):247-253. doi:
10.1248/bpb.b17-00803. [PMID: 29386484] - Manoj Kumar, Manish Kumar, John M Freund, Glenn H Dillon. A Single Amino Acid Residue at Transmembrane Domain 4 of the α Subunit Influences Carisoprodol Direct Gating Efficacy at GABAA Receptors.
The Journal of pharmacology and experimental therapeutics.
2017 09; 362(3):395-404. doi:
10.1124/jpet.117.242156. [PMID: 28642232] - Yang Song, Chun-Juan Yang, Zhi-Bin Wang, Nan Zhao, Xue-Song Feng, Fan-Hao Meng. Chemical constituents of Eleutherococcus sessiliflorus extract and its sedative-hypnotic effect.
Natural product research.
2017 Sep; 31(17):1995-2000. doi:
10.1080/14786419.2016.1272106. [PMID: 28049349] - Xin Li, Zichen Tang, Dongqing Fei, Yunhong Liu, Min Zhang, Shaoyang Liu. Evaluation of the sedative and hypnotic effects of astragalin isolated from Eucommia ulmoides leaves in mice.
Natural product research.
2017 Sep; 31(17):2072-2076. doi:
10.1080/14786419.2016.1272108. [PMID: 28013568] - Paula Pierozan, Fredrik Jernerén, Yusuf Ransome, Oskar Karlsson. The Choice of Euthanasia Method Affects Metabolic Serum Biomarkers.
Basic & clinical pharmacology & toxicology.
2017 Aug; 121(2):113-118. doi:
10.1111/bcpt.12774. [PMID: 28244216] - Paula Melo, Pedro Costa, Maria José Quintas, André Castro, Sónia Tarelho, João Miguel Franco, Helena M Teixeira. Pentobarbital in the context of possible suicides: Analysis of a Case.
Forensic science international.
2017 May; 274(?):109-112. doi:
10.1016/j.forsciint.2016.11.042. [PMID: 28007369] - Deirdre Edge, Christine M Shortt, E J Johns, Oliviero L Gobbo, Farouk Markos, Mohammed H Abdulla, Elaine F Barry. Assessment of renal function in the anaesthetised rat following injection of superparamagnetic iron oxide nanoparticles.
Canadian journal of physiology and pharmacology.
2017 Apr; 95(4):443-446. doi:
10.1139/cjpp-2016-0405. [PMID: 28177696] - Anne M Fink, Caron Dean, Mariann R Piano, David W Carley. The pedunculopontine tegmentum controls renal sympathetic nerve activity and cardiorespiratory activities in nembutal-anesthetized rats.
PloS one.
2017; 12(11):e0187956. doi:
10.1371/journal.pone.0187956. [PMID: 29121095] - Xin-Guo Zhang, Wen-Na Wang, Chun-Sheng Zhang, Kun Li, Guo-Di Ma, Jian-Yong Li. Expression and Purification of Delta Sleep-Inducing Peptide Fused with Protein Transduction Domain and Human Serum Albumin in Pichia pastoris.
Protein and peptide letters.
2017; 24(7):668-675. doi:
10.2174/0929866524666170426113022. [PMID: 28462721] - Noriyuki Nakatsu, Yoshinobu Igarashi, Taiki Aoshi, Isao Hamaguchi, Masumichi Saito, Takuo Mizukami, Haruka Momose, Ken J Ishii, Hiroshi Yamada. Isoflurane is a suitable alternative to ether for anesthetizing rats prior to euthanasia for gene expression analysis.
The Journal of toxicological sciences.
2017; 42(4):491-497. doi:
10.2131/jts.42.491. [PMID: 28717108] - Yusuke Sano, Shogo Ito, Mamoru Yoneda, Kai Nagasawa, Natsumi Matsuura, Yuichiro Yamada, Ayako Uchinaka, Yasuko K Bando, Toyoaki Murohara, Kohzo Nagata. Effects of various types of anesthesia on hemodynamics, cardiac function, and glucose and lipid metabolism in rats.
American journal of physiology. Heart and circulatory physiology.
2016 12; 311(6):H1360-H1366. doi:
10.1152/ajpheart.00181.2016. [PMID: 27694213] - G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metges. Acute effects of general anesthesia with propofol, pentobarbital or isoflurane plus propofol on plasma metabolites and hormones in adult pigs.
Journal of animal science.
2016 Dec; 94(12):5182-5191. doi:
10.2527/jas.2016-1018. [PMID: 28046175] - Gabriela Ávila-Villarreal, María Eva González-Trujano, Azucena Ibeth Carballo-Villalobos, Berenice Aguilar-Guadarrama, Sara García-Jiménez, Diana Elizabeth Giles-Rivas, Patricia Castillo-España, Rafael Villalobos-Molina, Samuel Estrada-Soto. Anxiolytic-like effects and toxicological studies of Brickellia cavanillesii (Cass.) A. Gray in experimental mice models.
Journal of ethnopharmacology.
2016 Nov; 192(?):90-98. doi:
10.1016/j.jep.2016.07.006. [PMID: 27381041] - Francisco Javier Sierra-Valdez, J C Ruiz-Suárez, Ilse Delint-Ramirez. Pentobarbital modifies the lipid raft-protein interaction: A first clue about the anesthesia mechanism on NMDA and GABAA receptors.
Biochimica et biophysica acta.
2016 11; 1858(11):2603-2610. doi:
10.1016/j.bbamem.2016.07.011. [PMID: 27457704] - Hyejin Yang, Junsung Woo, Ae Nim Pae, Min Young Um, Nam-Chul Cho, Ki Duk Park, Minseok Yoon, Jiyoung Kim, C Justin Lee, Suengmok Cho. α-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Mice through GABAA-benzodiazepine Receptors.
Molecular pharmacology.
2016 Nov; 90(5):530-539. doi:
10.1124/mol.116.105080. [PMID: 27573669] - Hongyan Zhu, Lina Zhang, Guoli Wang, Zhongmei He, Yan Zhao, Yonghua Xu, Yugang Gao, Lianxue Zhang. Sedative and hypnotic effects of supercritical carbon dioxide fluid extraction from Schisandra chinensis in mice.
Journal of food and drug analysis.
2016 10; 24(4):831-838. doi:
10.1016/j.jfda.2016.05.005. [PMID: 28911622] - D Cao, Y Liu, J Li, J Gong. Isoflurane: An Ideal Anesthetic for Rodent Orthotopic Liver Transplantation Surgery?.
Transplantation proceedings.
2016 Oct; 48(8):2815-2820. doi:
10.1016/j.transproceed.2016.06.057. [PMID: 27788823] - Sidra Ishaq, Muhammad Adil Rasheed, Muhammad Ashraf, Imran Altaf, Saima Rehmat, Ghulam Fatima. Effect of calcium hypochlorite and chloramine on blood biochemistry and sodium pentobarbital induced sleeping time in mice.
Pakistan journal of pharmaceutical sciences.
2016 Sep; 29(5):1625-1632. doi:
NULL. [PMID: 27731822] - Rosendo Pérez-Isidoro, J C Ruiz-Suárez. Calcium and protons affect the interaction of neurotransmitters and anesthetics with anionic lipid membranes.
Biochimica et biophysica acta.
2016 09; 1858(9):2215-2222. doi:
10.1016/j.bbamem.2016.06.017. [PMID: 27362370] - Yoshinori Kobayashi, Hiroaki Takemoto, Ziqi Fua, Emiko Shimizu, Yukitaka Kinjo. Enhancement of Pentobarbital-induced Sleep by the Vaporized Essential Oil of Citrus keraji var. kabuchii and its Characteristic Component, y-Terpinene.
Natural product communications.
2016 Aug; 11(8):1175-1178. doi:
. [PMID: 30725585] - Zhijuan Cao, Wenling Dai, Ran Zhang, Lu Chen, Xiangyu Yang, Liang Hu, Li-Yang Chiang, Wentao Liu. Opening of the Adenosine Triphosphate-sensitive Potassium Channel Attenuates Morphine Tolerance by Inhibiting JNK and Astrocyte Activation in the Spinal Cord.
The Clinical journal of pain.
2016 07; 32(7):617-23. doi:
10.1097/ajp.0000000000000299. [PMID: 26626290] - Johanne A Windeløv, Jens Pedersen, Jens J Holst. Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice.
Physiological reports.
2016 Jun; 4(11):. doi:
10.14814/phy2.12824. [PMID: 27255361] - Fatemeh Abdollahnejad, Mahmoud Mosaddegh, Mohammad Kamalinejad, Javad Mirnajafi-Zadeh, Forough Najafi, Mehrdad Faizi. Investigation of sedative and hypnotic effects of Amygdalus communis L. extract: behavioral assessments and EEG studies on rat.
Journal of natural medicines.
2016 Apr; 70(2):190-7. doi:
10.1007/s11418-015-0958-9. [PMID: 26711831] - O A Adeoluwa, A O Aderibigbe, G O Agu. Pharmacological Evaluation of Central Nervous System Effects of Ethanol Leaf Extract of Olax Subscorpioidea in Experimental Animals.
Drug research.
2016 Apr; 66(4):203-10. doi:
10.1055/s-0035-1564137. [PMID: 26624003] - Yasuhiro Tsubokura, Toshio Kobayashi, Yutaka Oshima, Naoki Hashizume, Makoto Nakai, Shozo Ajimi, Nobuya Imatanaka. Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats.
The Journal of toxicological sciences.
2016; 41(5):595-604. doi:
10.2131/jts.41.595. [PMID: 27665769] - Robert M Humble, Alexandra Ehlers, Brittany L Pakalniskis, Cory Morris, Denny Drees, Jeff Kulhavy, Matthew D Krasowski. Therapeutic Drug Monitoring of Pentobarbital: Experience at an Academic Medical Center.
Therapeutic drug monitoring.
2015 Dec; 37(6):783-91. doi:
10.1097/ftd.0000000000000217. [PMID: 26565790] - Wenfang Zhao, Yun Li, William Ma, Yazhong Ge, Yahui Huang. A study on quality components and sleep-promoting effects of GABA black tea.
Food & function.
2015 Oct; 6(10):3393-8. doi:
10.1039/c5fo00265f. [PMID: 26290415] - Hao Liu, Zhi Song, Da-Guang Liao, Tian-Yi Zhang, Feng Liu, Kai Zhuang, Kui Luo, Liang Yang, Jing He, Jian-Ping Lei. Anticonvulsant and Sedative Effects of Eudesmin isolated from Acorus tatarinowii on mice and rats.
Phytotherapy research : PTR.
2015 Jul; 29(7):996-1003. doi:
10.1002/ptr.5337. [PMID: 25851178] - Xue-Yan Wu, Yu-Ting Hu, Lei Guo, Jing Lu, Qiong-Bin Zhu, Er Yu, Juan-Li Wu, Li-Gen Shi, Man-Li Huang, Ai-Min Bao. Effect of pentobarbital and isoflurane on acute stress response in rat.
Physiology & behavior.
2015 Jun; 145(?):118-21. doi:
10.1016/j.physbeh.2015.04.003. [PMID: 25846436] - Yuki Ota, Yukio Ago, Tatsunori Tanaka, Shigeru Hasebe, Yui Toratani, Yusuke Onaka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda. Anxiolytic-like effects of restraint during the dark cycle in adolescent mice.
Behavioural brain research.
2015 May; 284(?):103-11. doi:
10.1016/j.bbr.2015.02.010. [PMID: 25687845] - Kathryn A Morbitzer, J Dedrick Jordan, Denise H Rhoney. Vancomycin pharmacokinetic parameters in patients with acute brain injury undergoing controlled normothermia, therapeutic hypothermia, or pentobarbital infusion.
Neurocritical care.
2015 Apr; 22(2):258-64. doi:
10.1007/s12028-014-0079-4. [PMID: 25330755] - Yuefeng Li, Pingan Wu, Yanmei Ning, Xingke Yan, Tiantian Zhu, Chongbing Ma, Anguo Liu. Sedative and hypnotic effect of freeze-dried paeoniflorin and sini san freeze-dried powder in pentobarbital sodium-induced mice.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2014 Apr; 34(2):184-7. doi:
10.1016/s0254-6272(14)60076-5. [PMID: 24783931] - Aleksandar Rašković, Jelena Cvejić, Nebojša Stilinović, Svetlana Goločorbin-Kon, Saša Vukmirović, Neda Mimica-Dukić, Momir Mikov. Interaction between different extracts of Hypericum perforatum L. from Serbia and pentobarbital, diazepam and paracetamol.
Molecules (Basel, Switzerland).
2014 Mar; 19(4):3869-82. doi:
10.3390/molecules19043869. [PMID: 24686576] - Jean-François Renard, Frédéric Lecomte, Philippe Hubert, Xavier de Leval, Bernard Pirotte. N-(3-Arylaminopyridin-4-yl)alkanesulfonamides as pyridine analogs of nimesulide: cyclooxygenases inhibition, anti-inflammatory studies and insight on metabolism.
European journal of medicinal chemistry.
2014 Mar; 74(?):12-22. doi:
10.1016/j.ejmech.2013.12.033. [PMID: 24440378] - Zhenhua Jin, Sojin Kim, Suengmok Cho, In-Ho Kim, Daeseok Han, Young-Ho Jin. Potentiating effect of glabridin on GABAA receptor-mediated responses in dorsal raphe neurons.
Planta medica.
2013 Oct; 79(15):1408-12. doi:
10.1055/s-0033-1350698. [PMID: 23975867] - Ping Li, Megan M Eaton, Joe Henry Steinbach, Gustav Akk. The benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists.
Anesthesiology.
2013 Jun; 118(6):1417-25. doi:
10.1097/aln.0b013e318289bcd3. [PMID: 23407108] - M Katayama, P Jiamsripong, A E Bukatina, T R Lombari, E M McMahon, N M Gades, M Belohlavek. Optimized administration regimen of lopinavir for a myocardial ischaemia reperfusion study in Sprague-Dawley rats.
Laboratory animals.
2013 Apr; 47(2):122-6. doi:
10.1177/0023677213476864. [PMID: 23563365] - Sheikh Rayees, Rohit Sharma, Gurdarshan Singh, Ishtiyaq Ahmad Najar, Amarinder Singh, Dastagir Basheer Ahamad, Subash Chander Sharma, Manoj Kumar Tikoo, Vijay Kumar Gupta, Payare Lal Sangwan, Surjeet Singh, Surinder Koul, Rakesh Kamal Johri. Acute, sub-acute and general pharmacological evaluation of 5-(3,4-methylenedioxyphenyl)-4-ethyl-2E,4E-pentadienoic acid piperidide (SK-20): a novel drug bioavailability enhancer.
Environmental toxicology and pharmacology.
2013 Mar; 35(2):347-59. doi:
10.1016/j.etap.2012.08.007. [PMID: 23182722] - Wanna Sirisangtragul, Bungorn Sripanidkulchai. Moduratory effect of Thai traditional medicine (Yahom Tultavai) on hepatic cytochrome P450 enzymes and pentobarbital-induced sleeping in mice.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2013; 10(4):128-36. doi:
10.4314/ajtcam.v10i4.21. [PMID: 24146513] - Hyejin Yang, Young-Chul Lee, Kyoung-Sik Han, Harjinder Singh, Minseok Yoon, Ji-Hae Park, Chang-Won Cho, Suengmok Cho. Green and gold kiwifruit peel ethanol extracts potentiate pentobarbital-induced sleep in mice via a GABAergic mechanism.
Food chemistry.
2013 Jan; 136(1):160-3. doi:
10.1016/j.foodchem.2012.07.111. [PMID: 23017407] - Maria Pedro Guarino, Ana Isabel Santos, Miguel Mota-Carmo, Pedro Freire Costa. Effects of anaesthesia on insulin sensitivity and metabolic parameters in Wistar rats.
In vivo (Athens, Greece).
2013 Jan; 27(1):127-32. doi:
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Journal of the American Association for Laboratory Animal Science : JAALAS.
2013 Jan; 52(1):34-43. doi:
NULL. [PMID: 23562031] - Fei Du, Yi Zhang, Xiao-Hong Zhu, Wei Chen. Simultaneous measurement of glucose blood-brain transport constants and metabolic rate in rat brain using in-vivo 1H MRS.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2012 Sep; 32(9):1778-87. doi:
10.1038/jcbfm.2012.82. [PMID: 22714049] - Germain Sotoing Taïwe, Elisabeth Ngo Bum, Emmanuel Talla, Amadou Dawe, Fleur Clarisse Okomolo Moto, Gwladys Temkou Ngoupaye, Neteydji Sidiki, Bernard Dabole, Paul Désiré Djomeni Dzeufiet, Théophile Dimo, Michel De Waard. Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents.
Journal of ethnopharmacology.
2012 Aug; 143(1):213-20. doi:
10.1016/j.jep.2012.06.026. [PMID: 22750453] - Liang Xiong, Cheng Peng, Xiao-Fang Xie, Li Guo, Cheng-Jun He, Zhao Geng, Feng Wan, Ou Dai, Qin-Mei Zhou. Alkaloids isolated from the lateral root of Aconitum carmichaelii.
Molecules (Basel, Switzerland).
2012 Aug; 17(8):9939-46. doi:
10.3390/molecules17089939. [PMID: 22907155] - Pablinny Moreira Galdino, Marcus Vinícius Mariano Nascimento, Iziara Ferreira Florentino, Roberta Campos Lino, James Oluwagbamigbe Fajemiroye, Beatriz Abdallah Chaibub, José Realino de Paula, Thereza Christina Monteiro de Lima, Elson Alves Costa. The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice.
Progress in neuro-psychopharmacology & biological psychiatry.
2012 Aug; 38(2):276-84. doi:
10.1016/j.pnpbp.2012.04.012. [PMID: 22542869] - Isidora Samojlik, Stojan Petković, Neda Mimica-Dukić, Biljana Božin. Acute and chronic pretreatment with essential oil of peppermint (Mentha × piperita L., Lamiaceae) influences drug effects.
Phytotherapy research : PTR.
2012 Jun; 26(6):820-5. doi:
10.1002/ptr.3638. [PMID: 22076909] - Suengmok Cho, Ji-Hae Park, Ae Nim Pae, Daeseok Han, Dongsoo Kim, Nam-Chul Cho, Kyoung Tai No, Hyejin Yang, Minseok Yoon, Changho Lee, Makoto Shimizu, Nam-In Baek. Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol.
Bioorganic & medicinal chemistry.
2012 Jun; 20(11):3493-501. doi:
10.1016/j.bmc.2012.04.011. [PMID: 22543233] - M Brückner, C S Schwedes. Successful treatment of permethrin toxicosis in two cats with an intravenous lipid administration.
Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere.
2012 Apr; 40(2):129-34. doi:
10.1055/s-0038-1623631. [PMID: 22526817] - Agung Nugroho, Myung-Hoe Kim, Jongwon Choi, Jae Sue Choi, Won Tae Jung, Kyung-Tae Lee, Hee-Juhn Park. Phytochemical studies of the phenolic substances in Aster glehni extract and its sedative and anticonvulsant activity.
Archives of pharmacal research.
2012 Mar; 35(3):423-30. doi:
10.1007/s12272-012-0304-7. [PMID: 22477188] - Norbert Kummerfeld, Marko Legler, Peter Wohlsein, Maren Kummerfeld. [Morphological studies in different avian species on artefacts induced by euthanasia with T 61 " or Pentobarbital (Narcoren)].
Berliner und Munchener tierarztliche Wochenschrift.
2012 Jan; 125(1-2):27-31. doi:
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Natural product research.
2012; 26(22):2095-8. doi:
10.1080/14786419.2011.613388. [PMID: 21988208] - M Herrera-Ruiz, A Zamilpa, M González-Cortazar, R Reyes-Chilpa, E León, M P García, J Tortoriello, M Huerta-Reyes. Antidepressant effect and pharmacological evaluation of standardized extract of flavonoids from Byrsonima crassifolia.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 Nov; 18(14):1255-61. doi:
10.1016/j.phymed.2011.06.018. [PMID: 21788126] - Karyn Bischoff, Robin Jaeger, Joseph G Ebel. An unusual case of relay pentobarbital toxicosis in a dog.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2011 Sep; 7(3):236-9. doi:
10.1007/s13181-011-0160-8. [PMID: 21660622] - Kuichang Hua, Lei Zhang, Zhenhui Zhang, Yong Guo, Tianying Guo. Surface hydrophilic modification with a sugar moiety for a uniform-sized polymer molecularly imprinted for phenobarbital in serum.
Acta biomaterialia.
2011 Aug; 7(8):3086-93. doi:
10.1016/j.actbio.2011.05.006. [PMID: 21605708] - Mohan G Kalaskar, Sanjay J Surana. Free radical scavenging and hepatoprotective potential of Ficus microcarpa L. fil. bark extracts.
Journal of natural medicines.
2011 Jul; 65(3-4):633-40. doi:
10.1007/s11418-011-0532-z. [PMID: 21625948] - Yu-Feng Chen, Ming-Hong Zhao, Ming Yan, Guo-Bing Shi, Guan-Xin Hou, Ying Huang, Xin Wang, Qin-Chun Zhao. Analgesic activity of the aqueous fraction from the ethanolic extract of Chrysanthemum indicum in mice.
Die Pharmazie.
2011 Jul; 66(7):538-42. doi:
". [PMID: 21812331]