liothyronine (BioDeep_00000405232)

Main id: BioDeep_00000002932

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


liothyronine

化学式: C15H12I3NO4 (650.7901)
中文名称: 3,3,5-三碘-L-甲腺原氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O
InChI: InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1553 - Thyroid Agent
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3].

同义名列表

5 个代谢物同义名

liothyronine; Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3; Triiodothyronine



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 BGLAP, CAT, HPGDS, POMC, PRL, THRSP
Peripheral membrane protein 1 ACHE
Endoplasmic reticulum membrane 1 DIO1
Nucleus 5 ACHE, PRL, THRA, THRB, THRSP
cytosol 5 CAT, GPT, HPGDS, THRA, THRSP
dendrite 1 BGLAP
nuclear body 1 THRB
nucleoplasm 5 HPGDS, PRL, THRA, THRB, THRSP
RNA polymerase II transcription regulator complex 3 PRL, THRA, THRB
Cell membrane 2 ACHE, TSHR
Multi-pass membrane protein 1 TSHR
Synapse 1 ACHE
cell surface 3 ACHE, TPO, TSHR
Golgi apparatus 1 ACHE
neuromuscular junction 1 ACHE
plasma membrane 5 ACHE, DIO1, GCG, TPO, TSHR
Membrane 5 ACHE, CAT, DIO1, TPO, TSHR
basolateral plasma membrane 1 TSHR
extracellular exosome 4 CAT, GPT, SERPINA7, TTR
extracellular space 11 ACHE, BGLAP, GCG, IGF1, POMC, PRL, PTH, SERPINA7, TG, TPO, TTR
perinuclear region of cytoplasm 1 ACHE
mitochondrion 1 CAT
protein-containing complex 1 CAT
intracellular membrane-bounded organelle 2 CAT, HPGDS
Single-pass type I membrane protein 1 TPO
Secreted 9 ACHE, BGLAP, GCG, IGF1, POMC, PRL, TG, TRH, TTR
extracellular region 12 ACHE, BGLAP, CAT, GCG, IGF1, POMC, PRL, PTH, SERPINA7, TG, TRH, TTR
Single-pass membrane protein 1 DIO1
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
perikaryon 1 BGLAP
vesicle 1 BGLAP
focal adhesion 1 CAT
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 2 POMC, TRH
lateral plasma membrane 1 TSHR
receptor complex 1 TSHR
chromatin 3 PRL, THRA, THRB
Basolateral cell membrane 1 TSHR
Lipid-anchor, GPI-anchor 1 ACHE
Endomembrane system 1 DIO1
endosome lumen 1 PRL
side of membrane 1 ACHE
exocytic vesicle 1 IGF1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, GCG, POMC
Golgi lumen 1 BGLAP
endoplasmic reticulum lumen 2 BGLAP, GCG
platelet alpha granule lumen 1 IGF1
azurophil granule lumen 1 TTR
synaptic cleft 1 ACHE
[Glucagon-like peptide 1]: Secreted 1 GCG
catalase complex 1 CAT
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
[Isoform Alpha-2]: Cytoplasm 1 THRA
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • Yang Li, Wen Yang, Xuewei Yang, Aijia Ma, Xuepeng Zhang, Hongxia Li, Hui Wu. Quemeiteng granule relieves goiter by suppressing thyroid microvascular endothelial cell proliferation and angiogenesis via miR-217-5p-mediated targeting of FGF2-induced regulation of the ERK pathway. Journal of ethnopharmacology. 2024 May; 326(?):117908. doi: 10.1016/j.jep.2024.117908. [PMID: 38367931]
  • Lin-Na Xie, Xiao-Chen Wang, Li-Qin Su, Sai-Sai Ji, Wen Gu, Holly Barrett, Xiao-Jie Dong, Hui-Juan Zhu, Sha-Sha Hou, Zhen-Huan Li, Yi-Lin Liu, Ling Zhang, Ying Zhu. The association between per-/polyfluoroalkyl substances in serum and thyroid function parameters: A cross-sectional study on teenagers living near a Chinese fluorochemical industrial plant. The Science of the total environment. 2024 Apr; 920(?):170985. doi: 10.1016/j.scitotenv.2024.170985. [PMID: 38367719]
  • James C Fazioli, Margaret K Mulligan, Erin K Ison, J Alex Pasternak. Impact of methimazole-induced hypothyroidism on postnatal swine. Physiological reports. 2024 Apr; 12(8):e16007. doi: 10.14814/phy2.16007. [PMID: 38658325]
  • Issac Sachmechi, Kathryn Jean Lucas, Larry D Stonesifer, John Fitzgerald Ansley, Paul Sack, Francesco S Celi, Claudia Scarsi, Gabriele Lanzi, Leonard Wartofsky, Kenneth D Burman. Efficacy of Levothyroxine Sodium Soft Gelatin Capsules in Thyroidectomized Patients Taking Proton Pump Inhibitors: An Open-Label Study. Thyroid : official journal of the American Thyroid Association. 2023 Nov; ?(?):. doi: 10.1089/thy.2023.0382. [PMID: 37885233]
  • Muyun Li, Linlin Xiu, Wenyong Liao, Yuna Ren, Min Huo, Haiyan Liu, Shaohong Chen, Na Li, Yuan Gao, Xue Yu, Angran Fan, Gansheng Zhong. Exploring the effect and mechanism of Haizao Yuhu decoction containing three variants of glycyrrhiza on goiter using an integrated strategy of network pharmacology and RNA sequencing. Journal of ethnopharmacology. 2023 Nov; 316(?):116750. doi: 10.1016/j.jep.2023.116750. [PMID: 37295576]
  • V Calcaterra, A Gazzarri, A De Silvestri, C Madia, P Baldassarre, V Rossi, V Garella, G Zuccotti. Thyroid function, sensitivity to thyroid hormones, and metabolic syndrome in euthyroid children and adolescents with Down syndrome. Journal of endocrinological investigation. 2023 Nov; 46(11):2319-2325. doi: 10.1007/s40618-023-02086-4. [PMID: 37040064]
  • Xin Zhao, Jianbin Sun, Xiumei Xu, Sixu Xin, Xiaomei Zhang. The effect of Central and peripheral thyroid resistance indices on diabetic retinopathy: a study of hospitalized euthyroid patients with T2DM in China. Annals of medicine. 2023 Aug; ?(?):2249017. doi: 10.1080/07853890.2023.2249017. [PMID: 37634057]
  • Selin Kir, Suheyla Gorar, Isilay Kalan Sari, Hamit Yasar Ellidag, Ayhan Hilmi Cekin, Esin Yilmaz. Omentin-1 Levels in Hypothyroid Patients with Autoimmune Thyroiditis. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. 2023 Aug; 33(8):842-846. doi: 10.29271/jcpsp.2023.08.842. [PMID: 37553919]
  • Yanchun Lin, Amy E Riek, Ann M Gronowski, Christopher W Farnsworth. Limited Utility of Free Triiodothyronine Testing. The journal of applied laboratory medicine. 2023 Jul; ?(?):. doi: 10.1093/jalm/jfad032. [PMID: 37473430]
  • Yan Zhang, Hua-Li Wang, Chao-Qiong Zhou, Da-Hai He, Feng Wu, Hong-Chuan Li, Qian-Rong Xie, Yu Luo, Li-Rui Kong. Intraday Changes and Clinical Applications of Thyroid Function Biomarkers in Healthy Subjects. Laboratory medicine. 2023 May; 54(3):282-286. doi: 10.1093/labmed/lmac105. [PMID: 36222001]
  • Zhifeng Chen, Binaya Wasti, Yulin Shang, Aijun Jia, Xudong Xiang, Ruoyun Ouyang. Clinical characteristics and risk factors of patients with eosinophilic fasciitis associated with pleural effusion. Scientific reports. 2023 Apr; 13(1):5452. doi: 10.1038/s41598-023-32678-2. [PMID: 37012347]
  • Lucas Solla Mathias, Carina Herman-de-Sousa, Sarah Santiloni Cury, Célia Regina Nogueira, Paulo Correia-de-Sá, Miriane de Oliveira. RNA-seq reveals that anti-obesity irisin and triiodothyronine (T3) hormones differentially affect the purinergic signaling transcriptomics in differentiated human adipocytes. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2023 Apr; 1868(4):159276. doi: 10.1016/j.bbalip.2022.159276. [PMID: 36642213]
  • Mei Qiu, Fangjun Luo, Lixin Du. Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?. Endocrine. 2023 04; 80(1):231. doi: 10.1007/s12020-022-03255-w. [PMID: 36378244]
  • Rafael Aguiar Marschner, Ana Cristina Roginski, Rafael Teixeira Ribeiro, Larisse Longo, Mário Reis Álvares-da-Silva, Simone Magagnin Wajner. Uncovering Actions of Type 3 Deiodinase in the Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD). Cells. 2023 03; 12(7):. doi: 10.3390/cells12071022. [PMID: 37048095]
  • Meng-Chao Liu, Jia-Lin Li, Yue-Fen Wang, Yuan Meng, Zhen Cai, Cun Shen, Meng-di Wang, Wen-Jing Zhao, Wen-Quan Niu. Association between thyroid hormones and diabetic kidney disease in Chinese adults. BMC endocrine disorders. 2023 Mar; 23(1):56. doi: 10.1186/s12902-023-01299-1. [PMID: 36882783]
  • Yijia Liu, Mei Ma, Lin Li, Fanfan Liu, Zhu Li, Lu Yu, Tong Yang, Yang Wang, Shan Gao, Sheng Gao, Rongrong Yang, Chunquan Yu. Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease. Endocrine. 2023 03; 79(3):459-468. doi: 10.1007/s12020-022-03254-x. [PMID: 36434323]
  • Yiruo Ma, Siyi Shen, Ying Yan, Shengjie Zhang, Shengnan Liu, Zhili Tang, Jing Yu, Mei Ma, Zhoumin Niu, Zhuoyang Li, Yuting Wu, Lin Zhao, Zhiqiang Lu, Chunchun Wei, Weiping J Zhang, Ying Xue, Qiwei Zhai, Yu Li, Cheng Hu, Jingjing Jiang, Yuying Li, Hao Ying. Adipocyte thyroid hormone β receptor-mediated hormone action fine-tunes the intracellular glucose and lipid metabolism and systemic homeostasis. Diabetes. 2023 Feb; ?(?):. doi: 10.2337/db22-0656. [PMID: 36724137]
  • A Tropeano, D Corica, S Curatola, A Li Pomi, C Casto, A Alibrandi, G Pepe, T Aversa, M Wasniewska. The effect of obesity-related allostatic changes on cardio-metabolic risk in euthyroid children. Journal of endocrinological investigation. 2023 Feb; 46(2):285-295. doi: 10.1007/s40618-022-01899-z. [PMID: 35986868]
  • Chengfei Zhang, Qiue Zhang, Lingling Qin, Zhiyi Yan, Lili Wu, Tonghua Liu. Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling. Drug design, development and therapy. 2023; 17(?):2273-2285. doi: 10.2147/dddt.s410901. [PMID: 37551407]
  • Mei Liu, An Li, Lingling Meng, Gaoxin Zhang, Xiaoling Guan, Jiang Zhu, Yingming Li, Qinghua Zhang, Guibin Jiang. Exposure to Novel Brominated Flame Retardants and Organophosphate Esters and Associations with Thyroid Cancer Risk: A Case-Control Study in Eastern China. Environmental science & technology. 2022 12; 56(24):17825-17835. doi: 10.1021/acs.est.2c04759. [PMID: 36468700]
  • Qingxu Liu, Xiaoqin Yin, Pin Li. Clinical, hormonal, and biochemical characteristics of 70 chinese children with moderate to severe type 1 diabetic ketoacidosis. BMC endocrine disorders. 2022 Dec; 22(1):301. doi: 10.1186/s12902-022-01227-9. [PMID: 36460989]
  • Mengqi Zhang, Fengmin Huang, Feiyu Jiang, Meiting Mai, Xiaorou Guo, Ying Zhang, Ying Xu, Hengbing Zu. Clinical efficacy and safety of low-dose doxepin in Chinese patients with generalized anxiety disorder: A before-after study. Medicine. 2022 Oct; 101(42):e31201. doi: 10.1097/md.0000000000031201. [PMID: 36281170]
  • Kyeezu Kim, Maria Argos, Victoria W Persky, Sally Freels, Robert M Sargis, Mary E Turyk. Associations of exposure to metal and metal mixtures with thyroid hormones: Results from the NHANES 2007-2012. Environmental research. 2022 Sep; 212(Pt C):113413. doi: 10.1016/j.envres.2022.113413. [PMID: 35537494]
  • Kaihong Xu, Zichen Feng, Francis Kojo Afrim, Jun Ma, Shuo Yang, Xuanyin Zhang, Zeyuan Niu, Ning An, Yuhui Du, Fangfang Yu, Guoyu Zhou, Yue Ba. Interaction of fluoride exposure and CREB1 gene polymorphisms on thyroid function in school-age children. Chemosphere. 2022 Sep; 303(Pt 2):135156. doi: 10.1016/j.chemosphere.2022.135156. [PMID: 35640685]
  • Elisa Merchan-Ramirez, Guillermo Sanchez-Delgado, Cristina Arrizabalaga-Arriazu, Francisco M Acosta, Maria Jose Arias-Tellez, Manuel Muñoz-Torres, Jose V Garcia-Lario, Jose M Llamas-Elvira, Jonatan R Ruiz. Circulating concentrations of free triiodothyronine are associated with central adiposity and cardiometabolic risk factors in young euthyroid adults. Journal of physiology and biochemistry. 2022 Aug; 78(3):629-640. doi: 10.1007/s13105-022-00881-w. [PMID: 35381950]
  • Ichiro Yamauchi, Yoriko Sakane, Yukiko Okuno, Taku Sugawa, Takuro Hakata, Haruka Fujita, Kentaro Okamoto, Daisuke Taura, Takafumi Yamashita, Keisho Hirota, Yohei Ueda, Toshihito Fujii, Akihiro Yasoda, Nobuya Inagaki. High-throughput Screening in Combination With a Cohort Study for Iodothyronine Deiodinases. Endocrinology. 2022 08; 163(8):. doi: 10.1210/endocr/bqac090. [PMID: 35695766]
  • Leonardo Vinicius Monteiro de Assis, Lisbeth Harder, José Thalles Lacerda, Rex Parsons, Meike Kaehler, Ingolf Cascorbi, Inga Nagel, Oliver Rawashdeh, Jens Mittag, Henrik Oster. Rewiring of liver diurnal transcriptome rhythms by triiodothyronine (T3) supplementation. eLife. 2022 07; 11(?):. doi: 10.7554/elife.79405. [PMID: 35894384]
  • Ying Wang, Sha Lu, Xianrong Xu, Lijun Zhang, Jun Yang, Wensheng Hu. The interactive effects of pre-pregnancy body mass index, thyroid function, and blood lipid levels on the risk of gestational diabetes mellitus: a crossover analysis. BMC pregnancy and childbirth. 2022 Jul; 22(1):580. doi: 10.1186/s12884-022-04908-4. [PMID: 35858832]
  • Shuai Chen, Xiaohe Sun, Guowei Zhou, Jie Jin, Zhiwei Li. Association between sensitivity to thyroid hormone indices and the risk of osteoarthritis: an NHANES study. European journal of medical research. 2022 Jul; 27(1):114. doi: 10.1186/s40001-022-00749-1. [PMID: 35820977]
  • Klara Gustin, Marie Vahter, Malin Barman, Bo Jacobsson, Helena Skröder, Helena Filipsson Nyström, Anna Sandin, Ann-Sofie Sandberg, Agnes E Wold, Maria Kippler. Assessment of Joint Impact of Iodine, Selenium, and Zinc Status on Women's Third-Trimester Plasma Thyroid Hormone Concentrations. The Journal of nutrition. 2022 Jul; 152(7):1737-1746. doi: 10.1093/jn/nxac081. [PMID: 35383840]
  • Xiao-Hui Liao, Pablo Avalos, Oksana Shelest, Raz Ofan, Michael Shilo, Catherine Bresee, Shibi Likhite, Jean-Philippe Vit, Heike Heuer, Brian Kaspar, Kathrin Meyer, Alexandra M Dumitrescu, Samuel Refetoff, Clive N Svendsen, Gad D Vatine. AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency. Thyroid : official journal of the American Thyroid Association. 2022 07; 32(7):849-859. doi: 10.1089/thy.2022.0034. [PMID: 35350867]
  • Zhigang Xie, Ibrahim M Ahmad, Lirong Zuo, Feng Xiao, Yongpeng Wang, Dongming Li. Hibernation with rhythmicity: the circadian clock and hormonal adaptations of the hibernating Asiatic toads (Bufo gargarizans). Integrative zoology. 2022 Jul; 17(4):656-669. doi: 10.1111/1749-4877.12613. [PMID: 34791783]
  • Sibel Demiral Sezer, Omercan Topaloglu. Effects of thyroid hormones in women with gestational diabetes. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 2022 Jul; 38(7):588-591. doi: 10.1080/09513590.2022.2076832. [PMID: 35604060]
  • Yushu Liu, Yanyi Huang, Guoheng Mo, Tao Zhou, Qian Hou, Chaoqun Shi, Jichun Yu, Yunxia Lv. Combined prognostic value of preoperative serum thyrotrophin and thyroid hormone concentration in papillary thyroid cancer. Journal of clinical laboratory analysis. 2022 Jul; 36(7):e24503. doi: 10.1002/jcla.24503. [PMID: 35666615]
  • Ekim Comert, Ulufer Celebi, Bilge Piri Cinar, Mustafa Acikgoz, Esra Aciman Demirel, Huseyin Tugrul Atasoy. Thyroid functions as a parameter in monitoring of antiepileptic drugs. Neurological research. 2022 Jul; 44(7):614-621. doi: 10.1080/01616412.2021.2025317. [PMID: 35019830]
  • Güldeniz Şekerci, Yavuz Erden, Suat Tekin. Effects of meteorin-like hormone on endocrine function of hypothalamo-hypophysial system and peripheral uncoupling proteins in rats. Molecular biology reports. 2022 Jul; 49(7):5919-5925. doi: 10.1007/s11033-022-07374-5. [PMID: 35332411]
  • Iordanis Mourouzis, Vassiliki Apostolaki, Athanasios Trikas, Leonidas Kokkinos, Natassa Alexandrou, Maria Avdikou, Myrto Giannoulopoulou, Aimilia Vassi, Ioulia Tseti, Constantinos Pantos. The Potential of Thyroid Hormone Therapy in Severe COVID-19: Rationale and Preliminary Evidence. International journal of environmental research and public health. 2022 Jun; 19(13):. doi: 10.3390/ijerph19138063. [PMID: 35805716]
  • Jinfeng Xiao, Chonggui Zhu, Xinxin Zhang, Longhao Sun, Chang Gao, Xiaoyu Liang, Qing He, Ming Liu. Associations among FT4 level, FT3/FT4 ratio, and non-alcoholic fatty liver disease in Chinese patients with hypopituitarism. Endocrine journal. 2022 Jun; 69(6):659-667. doi: 10.1507/endocrj.ej21-0536. [PMID: 35034938]
  • Sachiko Nakamura, Nozomi Kido, Miki Watanabe, Yuka Ohmachi, Yuko Inayama, Yuya Kashitani, Keiko Ishii, Ikuhiro Ishida, Naho Goda, Yasunori Fujita, Keiji Iida. Analysis of thyroid function in Japanese patients with coronavirus disease 2019. Endocrine journal. 2022 Jun; 69(6):643-648. doi: 10.1507/endocrj.ej21-0609. [PMID: 34955465]
  • Adeleh Esform, Tahereh Farkhondeh, Saeed Samarghandian, Maryam Rezaei, Ali Naghizadeh. Environmental arsenic exposure and its toxicological effect on thyroid function: a systematic review. Reviews on environmental health. 2022 Jun; 37(2):281-289. doi: 10.1515/reveh-2021-0025. [PMID: 34090316]
  • Emre Urhan, Zuleyha Karaca, Canan Sehit Kara, Zeynep Ture Yuce, Kursad Unluhizarci. The potential impact of COVID-19 on thyroid gland volumes among COVID-19 survivors. Endocrine. 2022 Jun; 76(3):635-641. doi: 10.1007/s12020-022-03019-6. [PMID: 35239124]
  • H Salman Jasim, N Khalid Shafeeq, E A A Abass. Vitamin D Level and its Relation with the Newly Diagnosed Diabetic Neuropathy in Women with Hypothyroidism. Archives of Razi Institute. 2022 06; 77(3):1139-1145. doi: 10.22092/ari.2022.357389.2029. [PMID: 36618309]
  • Ceyhun Bereketoglu, Ajay Pradhan. Plasticizers: negative impacts on the thyroid hormone system. Environmental science and pollution research international. 2022 Jun; 29(26):38912-38927. doi: 10.1007/s11356-022-19594-0. [PMID: 35303231]
  • Ya Zhang, Ruijie Xie, Jun Ou. A U-shaped association between serum albumin with total triiodothyronine in adults. Journal of clinical laboratory analysis. 2022 Jun; 36(6):e24473. doi: 10.1002/jcla.24473. [PMID: 35524426]
  • Qiu Li, Benqiang Yao, Shiting Zhao, Zhou Lu, Yan Zhang, Qiuping Xiang, Xishan Wu, Haonan Yu, Cheng Zhang, Junhua Li, Xiaoxi Zhuang, Donghai Wu, Yong Li, Yong Xu. Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist. Journal of medicinal chemistry. 2022 05; 65(10):7193-7211. doi: 10.1021/acs.jmedchem.2c00144. [PMID: 35507418]
  • Eleonora Nicolai, Marzia Nuccetelli, Serena Sarubbi, Valerio Basile, Marco Alfonso Perrone, Alessandro Terrinoni, Marilena Minieri, Massimo Pieri, Sergio Bernardini. Performance evaluation of the new Chemiluminescence Immunoassay CL-1200i Thyroid Panel. Journal of immunoassay & immunochemistry. 2022 May; 43(3):333-345. doi: 10.1080/15321819.2021.2017301. [PMID: 34927566]
  • Mohamed M Elgebaly, Asmaa R Abdel-Hamed, Noha M Mesbah, Dina M Abo-Elmatty, Amr Abouzid, Mohamed A Abdelrazek. Hypothyroidism affect progression and worse outcomes of breast cancer but not ovarian cancer. Journal of immunoassay & immunochemistry. 2022 May; 43(3):288-298. doi: 10.1080/15321819.2021.2001003. [PMID: 34787075]
  • Zhong-Ru Tang, Shen-Yue Chen, Wei Lu, Hao-Di Zhang, Ming Li, Jin-Song Liu. Morphological and physiological correlates of among- individual variation in basal metabolic rate in two passerine birds. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2022 05; 267(?):111160. doi: 10.1016/j.cbpa.2022.111160. [PMID: 35124186]
  • Domenico Salvatore, Tommaso Porcelli, Matthew D Ettleson, Antonio C Bianco. The relevance of T3 in the management of hypothyroidism. The lancet. Diabetes & endocrinology. 2022 05; 10(5):366-372. doi: 10.1016/s2213-8587(22)00004-3. [PMID: 35240052]
  • Patrick Quinlan, Alexandra Horvath, Carl Eckerström, Anders Wallin, Johan Svensson. Higher thyroid function is associated with accelerated hippocampal volume loss in Alzheimer's disease. Psychoneuroendocrinology. 2022 05; 139(?):105710. doi: 10.1016/j.psyneuen.2022.105710. [PMID: 35278981]
  • Yao Gao, Liang Zhao, Jun Seok Son, Xiangdong Liu, Yanting Chen, Jeanene Marie Deavila, Mei-Jun Zhu, Gordon K Murdoch, Min Du. Maternal Exercise Before and During Pregnancy Facilitates Embryonic Myogenesis by Enhancing Thyroid Hormone Signaling. Thyroid : official journal of the American Thyroid Association. 2022 05; 32(5):581-593. doi: 10.1089/thy.2021.0639. [PMID: 35286177]
  • Rosaria Sciarrillo, Alessandra Falzarano, Vito Gallicchio, Aldo Mileo, Maria De Falco. Toxic Effects on Thyroid Gland of Male Adult Lizards (Podarcis Siculus) in Contact with PolyChlorinated Biphenyls (PCBs)-Contaminated Soil. International journal of molecular sciences. 2022 Apr; 23(9):. doi: 10.3390/ijms23094790. [PMID: 35563180]
  • Li Wang, Youde Liu, Haifeng Yu, Kun Ding, Zhiqiang Zou. Low serum free triiodothyronineis level predicts worse outcome of patients with severe fever with thrombocytopenia syndrome. BMC infectious diseases. 2022 Apr; 22(1):391. doi: 10.1186/s12879-022-07367-6. [PMID: 35443632]
  • Adrian Post, Erwin Garcia, Eke G Gruppen, Daan Kremer, Margery A Connelly, Stephan J L Bakker, Robin P F Dullaart. Higher Free Triiodothyronine Is Associated With Higher HDL Particle Concentration and Smaller HDL Particle Size. The Journal of clinical endocrinology and metabolism. 2022 04; 107(5):e1807-e1815. doi: 10.1210/clinem/dgac044. [PMID: 35106588]
  • Budour Alkaf, Mohsin Siddiqui, Tomader Ali, Ali Bakir, Kevin Murphy, Karim Meeran, Nader Lessan. Ramadan Fasting and Changes in Thyroid Function in Hypothyroidism: Identifying Patients at Risk. Thyroid : official journal of the American Thyroid Association. 2022 04; 32(4):368-375. doi: 10.1089/thy.2021.0512. [PMID: 35152772]
  • C Sparano, E Zago, A Morettini, C Nozzoli, D Yannas, V Adornato, E Caldini, M Vaudo, M Maggi, L Petrone. Euthyroid sick syndrome as an early surrogate marker of poor outcome in mild SARS-CoV-2 disease. Journal of endocrinological investigation. 2022 Apr; 45(4):837-847. doi: 10.1007/s40618-021-01714-1. [PMID: 34850365]
  • Zi-Xuan Zhuang, Shuen-Ei Chen, Chih-Feng Chen, En-Chung Lin, San-Yuan Huang. Single-nucleotide polymorphisms in genes related to oxidative stress and ion channels in chickens are associated with semen quality and hormonal responses to thermal stress. Journal of thermal biology. 2022 Apr; 105(?):103220. doi: 10.1016/j.jtherbio.2022.103220. [PMID: 35393054]
  • Laszlo Hegedüs, Antonio C Bianco, Jacqueline Jonklaas, Simon H Pearce, Anthony P Weetman, Petros Perros. Primary hypothyroidism and quality of life. Nature reviews. Endocrinology. 2022 04; 18(4):230-242. doi: 10.1038/s41574-021-00625-8. [PMID: 35042968]
  • Chang Liu, Weichao Zheng, Lirong Zhu, Qin Tong, Du Li. Effect of elevated carbon dioxide on chicken eggs during the early and late incubation periods. Animal : an international journal of animal bioscience. 2022 Apr; 16(4):100499. doi: 10.1016/j.animal.2022.100499. [PMID: 35344888]
  • Linjie Weng, Guoqing Huang, Luping Gong, Jialu Xu, Yushan Mao, Yan Li, Mingcai Li. Low levels of serum IL-39 are associated with autoimmune thyroid disease. Journal of clinical laboratory analysis. 2022 Apr; 36(4):e24284. doi: 10.1002/jcla.24284. [PMID: 35182078]
  • Eva Miranda Marwali, Albert Lopolisa, Alvin A Sani, Muhammad Rayhan, Poppy S Roebiono, Dicky Fakhri, Nikolaus A Haas, April Slee, Michael A Portman. Indonesian Study: Triiodothyronine for Infants Less than 5 Months Undergoing Cardiopulmonary Bypass. Pediatric cardiology. 2022 Apr; 43(4):726-734. doi: 10.1007/s00246-021-02779-8. [PMID: 34851445]
  • Heleen I Jansen, Eveline Bruinstroop, Annemieke C Heijboer, Anita Boelen. Biomarkers indicating tissue thyroid hormone status: ready to be implemented yet?. The Journal of endocrinology. 2022 03; 253(2):R21-R45. doi: 10.1530/joe-21-0364. [PMID: 35256536]
  • Michela Bottani, Aasne K Aarsand, Giuseppe Banfi, Massimo Locatelli, Abdurrahman Coşkun, Jorge Díaz-Garzón, Pilar Fernandez-Calle, Sverre Sandberg, Ferruccio Ceriotti, Anna Carobene. European Biological Variation Study (EuBIVAS): within- and between-subject biological variation estimates for serum thyroid biomarkers based on weekly samplings from 91 healthy participants. Clinical chemistry and laboratory medicine. 2022 03; 60(4):523-532. doi: 10.1515/cclm-2020-1885. [PMID: 33561908]
  • Esterina Fazio, Arno Lindner, Cristina Cravana, Julia Wegener, Pietro Medica, Ulrich Hart-Mann, Adriana Ferlazzo. Effects of Standardized Exercise Tests on Plasma Thyroid Hormones' Kinetics in Standardbred Racehorses. Journal of equine veterinary science. 2022 03; 110(?):103853. doi: 10.1016/j.jevs.2021.103853. [PMID: 34968655]
  • Andrea Corrales Vargas, Jorge Peñaloza Castañeda, Emelie Rietz Liljedahl, Ana María Mora, Jose Antonio Menezes-Filho, Donald R Smith, Donna Mergler, Brian Reich, Andrew Giffin, Jane A Hoppin, Christian H Lindh, Berna van Wendel de Joode. Exposure to common-use pesticides, manganese, lead, and thyroid function among pregnant women from the Infants' Environmental Health (ISA) study, Costa Rica. The Science of the total environment. 2022 Mar; 810(?):151288. doi: 10.1016/j.scitotenv.2021.151288. [PMID: 34756903]
  • Rahul S Pawar, Satyanarayanaraju Sagi, Dmitry Leontyev. Determination of thyroid hormones in dietary supplements using liquid chromatography-tandem mass spectrometry. Drug testing and analysis. 2022 Mar; 14(3):578-586. doi: 10.1002/dta.3046. [PMID: 33855795]
  • Charles Bitamazire Businge, Benjamin Longo-Mbenza, Andre Pascal Kengne. Iodine deficiency in pregnancy along a concentration gradient is associated with increased severity of preeclampsia in rural Eastern Cape, South Africa. BMC pregnancy and childbirth. 2022 Feb; 22(1):98. doi: 10.1186/s12884-021-04356-6. [PMID: 35120491]
  • Siaw Li Chan, Samuel Refetoff, Nikolina Babic, Ming Jin, Uttam Garg, Kiang-Teck J Yeo. Triiodothyroacetic Acid Cross-Reacts With Measurement of Triiodothyronine (T3) on Various Immunoassay Platforms. American journal of clinical pathology. 2022 02; 157(2):156-158. doi: 10.1093/ajcp/aqab124. [PMID: 34542585]
  • Joseph Olusegun Ayo, Joseph Ayodele Obidi, Peter Ibrahim Rekwot, Barth Izuchukwu Onyeanusi. Modulatory effects of lycopene and vitamin E on cloacal temperature, thyroid hormonal and reproductive performance responses in laying hens during the hot-dry season. Journal of thermal biology. 2022 Feb; 104(?):103105. doi: 10.1016/j.jtherbio.2021.103105. [PMID: 35180978]
  • C Mele, L Pagano, D Franciotta, M Caputo, A Nardone, G Aimaretti, P Marzullo, V Pingue. Thyroid function in the subacute phase of traumatic brain injury: a potential predictor of post-traumatic neurological and functional outcomes. Journal of endocrinological investigation. 2022 Feb; 45(2):379-389. doi: 10.1007/s40618-021-01656-8. [PMID: 34351610]
  • Shubhajit Saha, Azubuike V Chukwuka, Dip Mukherjee, Kishore Dhara, Prasenjit Pal, Nimai Chandra Saha. Physiological (haematological, growth and endocrine) and biochemical biomarker responses in air-breathing catfish, Clarias batrachus under long-term Captan® pesticide exposures. Environmental toxicology and pharmacology. 2022 Feb; 90(?):103815. doi: 10.1016/j.etap.2022.103815. [PMID: 35065295]
  • Alexandra M Dumitrescu, Erin C Hanlon, Marilyn Arosemena, Olga Duchon, Matthew Ettleson, Mihai Giurcanu, Antonio C Bianco. Extended Absorption of Liothyronine from Poly-Zinc-Liothyronine: Results from a Phase 1, Double-Blind, Randomized, and Controlled Study in Humans. Thyroid : official journal of the American Thyroid Association. 2022 02; 32(2):196-205. doi: 10.1089/thy.2021.0304. [PMID: 34641706]
  • Åse-Karen Mortensen, Jonathan Verreault, Anthony François, Magali Houde, Maeva Giraudo, Maria Dam, Bjørn Munro Jenssen. Flame retardants and their associations with thyroid hormone-related variables in northern fulmars from the Faroe Islands. The Science of the total environment. 2022 Feb; 806(Pt 2):150506. doi: 10.1016/j.scitotenv.2021.150506. [PMID: 34601176]
  • Ichiro Yamauchi, Yoriko Sakane, Takafumi Yamashita, Takuro Hakata, Taku Sugawa, Haruka Fujita, Kentaro Okamoto, Daisuke Taura, Keisho Hirota, Yohei Ueda, Toshihito Fujii, Akihiro Yasoda, Nobuya Inagaki. Thyroid hormone economy in mice overexpressing iodothyronine deiodinases. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022 02; 36(2):e22141. doi: 10.1096/fj.202101288rr. [PMID: 34981562]
  • Paul J Davis, Hung-Yun Lin, Aleck Hercbergs, Kelly A Keating, Shaker A Mousa. Possible Contributions of Nongenomic Actions of Thyroid Hormones to the Vasculopathic Complex of COVID-19 Infection. Endocrine research. 2022 Feb; 47(1):39-44. doi: 10.1080/07435800.2021.1972307. [PMID: 34775877]
  • Asieh Mousavi, Negin Salamat, Alireza Safahieh. Phenanthrene disrupting effects on the thyroid system of Arabian seabream, Acanthopagrus arabicus: In situ and in vivo study. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022 Feb; 252(?):109226. doi: 10.1016/j.cbpc.2021.109226. [PMID: 34756986]
  • Rutchanna M S Jongejan, Evert F S van Velsen, Marcel E Meima, Theo Klein, Sjoerd A A van den Berg, Elske T Massolt, W Edward Visser, Robin P Peeters, Yolanda B de Rijke. Change in Thyroid Hormone Metabolite Concentrations Across Different Thyroid States. Thyroid : official journal of the American Thyroid Association. 2022 02; 32(2):119-127. doi: 10.1089/thy.2021.0453. [PMID: 34806412]
  • Ahmed A A Abdel-Wareth, Khaled R A Hussein, Zienhom S H Ismail, Jayant Lohakare. Effects of Zinc Oxide Nanoparticles on the Performance of Broiler Chickens Under Hot Climatic Conditions. Biological trace element research. 2022 Jan; ?(?):. doi: 10.1007/s12011-022-03095-9. [PMID: 34997923]
  • Yeqing Gu, Xiaohui Wu, Qing Zhang, Li Liu, Ge Meng, Hongmei Wu, Shunming Zhang, Yawen Wang, Tingjing Zhang, Xuena Wang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Kaijun Niu. High-Normal Thyroid Function Predicts Incident Nonalcoholic Fatty Liver Disease Among Middle-Aged and Older Euthyroid Subjects. The journals of gerontology. Series A, Biological sciences and medical sciences. 2022 01; 77(1):197-203. doi: 10.1093/gerona/glab037. [PMID: 33534875]
  • Yun Cai, Zhixiao Wang, Xiaoyun Liu, Ling Wei, Shushu Li, Xuqin Zheng, Tao Yang, Xinyu Xu. The Frequency of Intrathyroidal Follicular Helper T Cells Varies with the Progression of Graves' Disease and Hashimoto's Thyroiditis. Journal of immunology research. 2022; 2022(?):4075522. doi: 10.1155/2022/4075522. [PMID: 35224111]
  • Tugce Akman, Oya Topaloglu, Alparslan Altunoglu, Salim Neselioglu, Ozcan Erel. Frequency of Euthyroid Sick Syndrome before and after renal transplantation in patients with end stage renal disease and its association with oxidative stress. Postgraduate medicine. 2022 Jan; 134(1):52-57. doi: 10.1080/00325481.2021.1994267. [PMID: 34649484]
  • Qiuhong Liu, Han Li, Weiwei He, Qing Zhao, Caoxin Huang, Qingxuan Wang, Zeyu Zheng, Xiaofang Zhang, Xiulin Shi, Xuejun Li. Role of aerobic exercise in ameliorating NASH: Insights into the hepatic thyroid hormone signaling and circulating thyroid hormones. Frontiers in endocrinology. 2022; 13(?):1075986. doi: 10.3389/fendo.2022.1075986. [PMID: 36605939]
  • Jan Krátký. Levotyroxin. Vnitrni lekarstvi. 2022; 68(1):68-72. doi: NULL. [PMID: 35459350]
  • Shanshan Chen, George F Wohlford, Alessandra Vecchie', Salvatore Carbone, Sahzene Yavuz, Benjamin Van Tassell, Antonio Abbate, Francesco S Celi. Acute Effects of Liothyronine Administration on Cardiovascular System and Energy Metabolism in Healthy Volunteers. Frontiers in endocrinology. 2022; 13(?):843539. doi: 10.3389/fendo.2022.843539. [PMID: 35295986]
  • Feifei Ge, Lin Dong, Donglin Zhu, Xingjian Lin, Jingping Shi, Ming Xiao. Comparison of Serum Triiodothyronine with Biomarkers for Alzheimer's Disease Continuum in Euthyroid Subjects. Journal of Alzheimer's disease : JAD. 2022; 85(2):605-614. doi: 10.3233/jad-215092. [PMID: 34864671]
  • Shan Qiao, Shan-Chao Zhang, Ran-Ran Zhang, Lei Wang, Zhi-Hao Wang, Jing Jiang, Ai-Hua Wang, Xue-Wu Liu. Thyroid Function and Low Free Triiodothyronine in Chinese Patients With Autoimmune Encephalitis. Frontiers in immunology. 2022; 13(?):821746. doi: 10.3389/fimmu.2022.821746. [PMID: 35222399]
  • Tobias M Wolff, Johannes W Dietrich, Matthias A Müller. Optimal Hormone Replacement Therapy in Hypothyroidism - A Model Predictive Control Approach. Frontiers in endocrinology. 2022; 13(?):884018. doi: 10.3389/fendo.2022.884018. [PMID: 35813623]
  • Yijia Liu, Zhu Li, Tong Yang, Lin Li, Lu Yu, Fanfan Liu, Tongyao Ni, Shan Gao, Chunjie Li, Rongrong Yang, Chunquan Yu. Impaired sensitivity to thyroid hormones and carotid plaque in patients with coronary heart disease: A RCSCD-TCM study in China. Frontiers in endocrinology. 2022; 13(?):940633. doi: 10.3389/fendo.2022.940633. [PMID: 36237180]
  • V Calcaterra, G Biganzoli, D Dilillo, S Mannarino, L Fiori, G Pelizzo, E Zoia, V Fabiano, P Carlucci, A Camporesi, C Corti, G Mercurio, F Izzo, E Biganzoli, G Zuccotti. Non-thyroidal illness syndrome and SARS-CoV-2-associated multisystem inflammatory syndrome in children. Journal of endocrinological investigation. 2022 Jan; 45(1):199-208. doi: 10.1007/s40618-021-01647-9. [PMID: 34312809]
  • Amichay Meirovitz, Benjamin Nisman, Tanir M Allweis, Einat Carmon, Luna Kadouri, Bella Maly, Ofra Maimon, Tamar Peretz. Thyroid Hormones and Morphological Features of Primary Breast Cancer. Anticancer research. 2022 01; 42(1):253-261. doi: 10.21873/anticanres.15480. [PMID: 34969732]
  • Yue Song, Changqiang Yang, Hua Wang. Free Triiodothyronine Is Associated with Poor Outcomes after Acute Ischemic Stroke. International journal of clinical practice. 2022; 2022(?):1982193. doi: 10.1155/2022/1982193. [PMID: 35685519]
  • Vishal Patel, Amit Joharapurkar, Samadhan Kshirsagar, Maulik Patel, Hiren Patel, Hardikkumar Savsani, Mukul Jain. Microsomal triglyceride transfer protein inhibitor lomitapide-induced liver toxicity is ameliorated by Triiodothyronine treatment following improved bile homeostasis and β-oxidation. Toxicology and applied pharmacology. 2022 01; 434(?):115825. doi: 10.1016/j.taap.2021.115825. [PMID: 34902352]
  • Dumitru Cristinel Badiu, Gabriel Cristian Popescu, Anca Zgura, Adriana Mercan Stanciu, Mihai Daniel Dodot, Claudia Mehedintu, Letitia Toma, Simu Razvan, Xenia Bacinschi, Bogdan Haineala. A Prospective Observational Study of 42 Patients with COVID-19 infection and a History of Hepatitis C Virus Infection and Thyroid Disease with Follow-Up Thyroid Function and Autoantibody Testing. Medical science monitor : international medical journal of experimental and clinical research. 2021 Dec; 27(?):e935075. doi: 10.12659/msm.935075. [PMID: 34969944]
  • Elisa Flach, Julian Koenig, Patrice van der Venne, Peter Parzer, Franz Resch, Michael Kaess. Hypothalamic-pituitary-thyroid axis function in female adolescent nonsuicidal self-injury and its association with comorbid borderline personality disorder and depression. Progress in neuro-psychopharmacology & biological psychiatry. 2021 12; 111(?):110345. doi: 10.1016/j.pnpbp.2021.110345. [PMID: 33964324]
  • Masaaki Inaba, Katsuhito Mori, Yoshihiro Tsujimoto, Shinsuke Yamada, Yuko Yamazaki, Masanori Emoto, Tetsuo Shoji. Association of Reduced Free T3 to Free T4 Ratio with Lower Serum Creatinine in Japanese Hemodialysis Patients. Nutrients. 2021 Dec; 13(12):. doi: 10.3390/nu13124537. [PMID: 34960089]
  • Ilse Vanhorebeek, Inge Derese, Jan Gunst, Pieter J Wouters, Greet Hermans, Greet Van den Berghe. Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness. Critical care (London, England). 2021 12; 25(1):430. doi: 10.1186/s13054-021-03858-1. [PMID: 34915907]
  • Xia Sun, Liping Chen, Rongzhen Wu, Dan Zhang, Yinhui He. Association of thyroid hormone with body fat content and lipid metabolism in euthyroid male patients with type 2 diabetes mellitus: a cross-sectional study. BMC endocrine disorders. 2021 Dec; 21(1):241. doi: 10.1186/s12902-021-00903-6. [PMID: 34872554]
  • Salvatore Sciacchitano, Carlo Capalbo, Christian Napoli, Andrea Negro, Luciano De Biase, Adriano Marcolongo, Paolo Anibaldi, Valentina Salvati, Lea Petrella, Luca Merlo, Daniela Alampi, Elisa Alessandri, Chiara Loffredo, Alessandra Ulivieri, Luca Lavra, Fiorenza Magi, Alessandra Morgante, Leila B Salehi, Claudia De Vitis, Rita Mancini, Flaminia Coluzzi, Monica Rocco. Nonthyroidal illness syndrome (NTIS) in severe COVID-19 patients: role of T3 on the Na/K pump gene expression and on hydroelectrolytic equilibrium. Journal of translational medicine. 2021 12; 19(1):491. doi: 10.1186/s12967-021-03163-z. [PMID: 34861865]
  • D A Wittekind, J Kratzsch, R Mergl, R Baber, V Witte, A Villringer, M Kluge. Free triiodothyronine (T3) is negatively associated with fasting ghrelin serum levels in a population sample of euthyroid subjects. Journal of endocrinological investigation. 2021 Dec; 44(12):2655-2664. doi: 10.1007/s40618-021-01578-5. [PMID: 33881751]