REMIFENTANIL (BioDeep_00000398454)

Main id: BioDeep_00000002029

 


代谢物信息卡片


REMIFENTANIL

化学式: C20H28N2O5 (376.1998)
中文名称: 瑞芬太尼
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC
InChI: InChI=1S/C20H28N2O5/c1-4-17(23)22(16-8-6-5-7-9-16)20(19(25)27-3)11-14-21(15-12-20)13-10-18(24)26-2/h5-9H,4,10-15H2,1-3H3

描述信息

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
N - Nervous system > N01 - Anesthetics > N01A - Anesthetics, general > N01AH - Opioid anesthetics
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist
D002491 - Central Nervous System Agents > D000700 - Analgesics

同义名列表

2 个代谢物同义名

REMIFENTANIL; Remifentanil



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ABCB1, AXIN2, IL18, MAPK14, POMC
Endoplasmic reticulum membrane 1 CD4
Nucleus 2 AXIN2, MAPK14
cytosol 5 AVP, AXIN2, GPT, IL18, MAPK14
dendrite 2 AVP, OPRM1
trans-Golgi network 1 PCSK5
centrosome 1 AXIN2
nucleoplasm 1 MAPK14
Cell membrane 6 ABCB1, CD4, CD8A, OPRD1, OPRM1, TNF
Cell projection, axon 1 OPRM1
Multi-pass membrane protein 4 ABCB1, CACNA1I, OPRD1, OPRM1
Synapse 1 OPRM1
cell surface 2 ABCB1, TNF
glutamatergic synapse 1 MAPK14
Golgi apparatus 2 OPRM1, PCSK5
Golgi membrane 2 INS, PCSK5
neuronal cell body 1 TNF
presynaptic membrane 1 OPRD1
Cytoplasm, cytosol 1 IL18
endosome 1 OPRM1
plasma membrane 8 ABCB1, AXIN2, CACNA1I, CD4, CD8A, OPRD1, OPRM1, TNF
synaptic vesicle membrane 1 OPRD1
Membrane 5 ABCB1, CACNA1I, OPRD1, OPRM1, PCSK5
apical plasma membrane 1 ABCB1
axon 1 OPRM1
extracellular exosome 2 ABCB1, GPT
endoplasmic reticulum 1 OPRM1
extracellular space 11 AVP, CRP, CXCL8, IL10, IL18, IL6, INS, PCSK5, POMC, TCN1, TNF
mitochondrion 1 MAPK14
Single-pass type I membrane protein 2 CD4, CD8A
Secreted 8 AVP, CRP, CXCL8, IL10, IL18, IL6, INS, POMC
extracellular region 13 AVP, CD8A, CRP, CXCL8, IL10, IL18, IL6, INS, MAPK14, PCSK5, POMC, TCN1, TNF
[Isoform 2]: Secreted 1 CD8A
external side of plasma membrane 3 CD4, CD8A, TNF
perikaryon 1 OPRM1
beta-catenin destruction complex 1 AXIN2
Early endosome 1 CD4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Apical cell membrane 1 ABCB1
Membrane raft 2 CD4, TNF
secretory granule 2 AVP, POMC
nuclear speck 1 MAPK14
receptor complex 1 CD8A
neuron projection 2 OPRD1, OPRM1
phagocytic cup 1 TNF
spindle pole 1 MAPK14
endosome lumen 1 INS
Cell projection, dendrite 1 OPRM1
plasma membrane raft 1 CD8A
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 3 INS, MAPK14, POMC
Golgi lumen 2 INS, PCSK5
endoplasmic reticulum lumen 3 CD4, IL6, INS
axon terminus 1 OPRD1
voltage-gated calcium channel complex 1 CACNA1I
specific granule lumen 1 TCN1
tertiary granule lumen 1 TCN1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
postsynaptic density membrane 1 OPRD1
neuronal dense core vesicle 2 AVP, OPRD1
clathrin-coated endocytic vesicle membrane 2 AVP, CD4
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cell membrane 1 CD8A
dendrite membrane 1 OPRD1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 2 CD4, CD8A
interleukin-6 receptor complex 1 IL6
[Isoform 12]: Cytoplasm 1 OPRM1
spine apparatus 1 OPRD1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Zhenming Kang, Guoshao Zhu, Changsheng Su, Kai Zeng, Shunyuan Li, Xiaodan Wu. Differential effects of remifentanil and sufentanil anesthesia on post-operative pain and cognitive functions. International immunopharmacology. 2022 Jul; 108(?):108888. doi: 10.1016/j.intimp.2022.108888. [PMID: 35729829]
  • Nicole Wylie, Lee Beale, Ian Westley. Consistency of remifentanil concentrations in propofol-Remifentanil infusions. A laboratory-based study. Paediatric anaesthesia. 2022 06; 32(6):727-731. doi: 10.1111/pan.14427. [PMID: 35234322]
  • Jun Okuda, Takeshi Suzuki, Kenta Wakaizumi, Jungo Kato, Takashige Yamada, Hiroshi Morisaki. Effects of Thoracic Epidural Anesthesia on Systemic and Local Inflammatory Responses in Patients Undergoing Lung Cancer Surgery: A Randomized Controlled Trial. Journal of cardiothoracic and vascular anesthesia. 2022 05; 36(5):1380-1386. doi: 10.1053/j.jvca.2021.08.026. [PMID: 34518101]
  • M-X Yang, Z-Z Wu, X-Y Liao, B-L Zhang, X Chen, Y Wu, J-D Lin. Remifentanil reduces multiple organ and energy metabolism disturbances in a rat sepsis model. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2022 Feb; 73(1):. doi: 10.26402/jpp.2022.1.08. [PMID: 35639040]
  • Youqing Li, Jiangping Yu, Mingmin Zhang, Meng Jia. Clinical Application of Remifentanil Combined with Sevoflurane in Manual Reduction of Humeral Supracondylar Fracture in Children. Computational and mathematical methods in medicine. 2022; 2022(?):2410433. doi: 10.1155/2022/2410433. [PMID: 35844458]
  • Xiaojun Li, Zhenping Gui, Huizi Liu, Shaojie Qian, Yanan Jia, Xiaopan Luo. Remifentanil pretreatment ameliorates H/R-induced cardiac microvascular endothelial cell dysfunction by regulating the PI3K/Akt/HIF-1α signaling pathway. Bioengineered. 2021 12; 12(1):7872-7881. doi: 10.1080/21655979.2021.1969843. [PMID: 34612779]
  • Tae Kyun Kim. Obesity and anesthetic pharmacology: simulation of target-controlled infusion models of propofol and remifentanil. Korean journal of anesthesiology. 2021 12; 74(6):478-487. doi: 10.4097/kja.21345. [PMID: 34407372]
  • Ping-Ping Jiang, Yan-Xia Guo, Xiao-Lin Yang, Juan Xu, Dan Wang. Effects of different remifentanil target concentrations on MACBAR of sevoflurane in patients with liver dysfunction under carbon dioxide pneumoperitoneum stimulus: A randomized controlled trial. Journal of clinical pharmacy and therapeutics. 2021 Dec; 46(6):1776-1783. doi: 10.1111/jcpt.13524. [PMID: 34514614]
  • Dan Wang, Juan Xu, Xiao-Lin Yang, Yan-Xia Guo, Ping-Ping Jiang, Guo-Yuan Zhang. Effects of different plasma target concentrations of remifentanil on the MACBAR of sevoflurane in children with laparoscopic surgery. BMC anesthesiology. 2021 09; 21(1):231. doi: 10.1186/s12871-021-01453-z. [PMID: 34560835]
  • L Van Hese, E Cuypers, T Theys, A Absalom, S Rex. Comparison of predicted and real propofol and remifentanil concentrations in plasma and brain tissue during target-controlled infusion: a reply. Anaesthesia. 2021 06; 76(6):861-862. doi: 10.1111/anae.15452. [PMID: 33662142]
  • Y Luo, L Wang, G W Li, Z Y Yang, X Z Lin. [Dexmedetomidine up-regulates peripheral blood microRNA 183 to improve remifentanil-related hyperalgesia]. Zhonghua yi xue za zhi. 2021 May; 101(17):1246-1249. doi: 10.3760/cma.j.cn112137-20200825-02467. [PMID: 34865393]
  • Analía I Alet, Marcus V Batista da Silva, Horacio V Castellini, Nicolás A Alet, Bibiana D Riquelme. In vitro alteration on erythrocytes mechanical properties by propofol, remifentanil and vecuronium. Microvascular research. 2021 05; 135(?):104132. doi: 10.1016/j.mvr.2021.104132. [PMID: 33421433]
  • Sirkku Ahlström, Paula Bergman, Ritva Jokela, Linda Ottensmann, Ari Ahola-Olli, Matti Pirinen, Klaus T Olkkola, Mari A Kaunisto, Eija Kalso. First genome-wide association study on rocuronium dose requirements shows association with SLCO1A2. British journal of anaesthesia. 2021 May; 126(5):949-957. doi: 10.1016/j.bja.2021.01.029. [PMID: 33676726]
  • Hyung-Been Yhim, Hyung-Min Oh, Hyun-Kyu Yoon, Yong Hwy Kim, Hee-Pyoung Park. A Retrospective Observational Study of the Neuroendocrine Stress Response in Patients Undergoing Endoscopic Transsphenoidal Surgery for Removal of Pituitary Adenomas: Total Intravenous Versus Balanced Anesthesia. Journal of neurosurgical anesthesiology. 2021 Apr; 33(2):137-146. doi: 10.1097/ana.0000000000000638. [PMID: 31453876]
  • Natsuki Akashi, Yusuke Murahata, Masahumi Hosokawa, Yoshiaki Hikasa, Yoshiharu Okamoto, Tomohiro Imagawa. Cardiovascular and renal effects of constant rate infusions of remifentanil, dexmedetomidine and their combination in dogs anesthetized with sevoflurane. The Journal of veterinary medical science. 2021 Mar; 83(2):285-296. doi: 10.1292/jvms.20-0457. [PMID: 33310997]
  • Linda Y Tang, Jingping Wang. Response to 'Systematic Application of Rapid Sequence Intubation With Remifentanil During COVID-19 Pandemic'. Seminars in cardiothoracic and vascular anesthesia. 2021 03; 25(1):76. doi: 10.1177/1089253220943026. [PMID: 32696727]
  • Sergio Bevilacqua, Vanessa Bottari, Ilaria Galeotti. Systematic Application of Rapid Sequence Intubation With Remifentanil During COVID-19 Pandemic. Seminars in cardiothoracic and vascular anesthesia. 2021 Mar; 25(1):74-75. doi: 10.1177/1089253220941369. [PMID: 32664787]
  • Sandra Funcke, Hans O Pinnschmidt, Charlotte Brinkmann, Stefan Wesseler, Burkhard Beyer, Marlene Fischer, Rainer Nitzschke. Nociception level-guided opioid administration in radical retropubic prostatectomy: a randomised controlled trial. British journal of anaesthesia. 2021 02; 126(2):516-524. doi: 10.1016/j.bja.2020.09.051. [PMID: 33228979]
  • Elizabeth Jabbour, Carsten Fütterer, Sebastian Zach, Anna-Isabelle Kälsch, Michael Keese, Nuh N Rahbari, Bernhard K Krämer, Kay G Schwenke. Implantation of a peritoneal dialysis catheter in patients with ESRD using local anesthesia and Remifentanil. PloS one. 2021; 16(11):e0259351. doi: 10.1371/journal.pone.0259351. [PMID: 34735524]
  • Ning Yang, Ming Yang, Wenping Peng, Siwen Zhao, Jie Bao, Mingzhang Zuo. Comparison of anesthesia effects between closed-loop and open-loop target controlled infusion of propofol using the bispectral index in abdominal surgery. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2020 Dec; 45(12):1419-1424. doi: 10.11817/j.issn.1672-7347.2020.190489. [PMID: 33472997]
  • Jean Jung, Allan Kolodziej, Elise Pape, Michael Bisch, Lucie Javot, Valérie Gibaja, Jean-Yves Jouzeau, Julien Scala-Bertola, Nicolas Gambier. Multiplex detection of 14 fentanyl analogues and U-47700 in biological samples: Application to a panel of French hospitalized patients. Forensic science international. 2020 Dec; 317(?):110437. doi: 10.1016/j.forsciint.2020.110437. [PMID: 33007729]
  • Daneele Thorpe, Ryan T Lacy, Justin C Strickland. Acquisition of remifentanil self-administration: Enhanced in female rats but no effect of adolescent stress exposure. Pharmacology, biochemistry, and behavior. 2020 12; 199(?):173038. doi: 10.1016/j.pbb.2020.173038. [PMID: 32910927]
  • Zhiqiang Yu, Peijun Zhang, Haiyun Wang, Li Zhang, Wei Wei, Wenqian Fang, Xingbo Mu. Effects of dexmedetomidine versus remifentanil on mothers and neonates during cesarean section under general anesthesia. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 2020 Dec; 164(4):417-424. doi: 10.5507/bp.2019.055. [PMID: 31762471]
  • Anthony R Absalom, Ann E Rigby-Jones, Andrew R Rushton, J Robert Sneyd. De-mystifying the 'Mixifusor'. Paediatric anaesthesia. 2020 12; 30(12):1292-1298. doi: 10.1111/pan.14039. [PMID: 33051933]
  • L Van Hese, T Theys, A R Absalom, S Rex, E Cuypers. Comparison of predicted and real propofol and remifentanil concentrations in plasma and brain tissue during target-controlled infusion: a prospective observational study. Anaesthesia. 2020 12; 75(12):1626-1634. doi: 10.1111/anae.15125. [PMID: 32506561]
  • Rongsheng Zhou, Shuang Li, Xiaopeng Mei, Tao Jiang, Qiang Wang. Remifentanil up-regulates HIF1α expression to ameliorate hepatic ischaemia/reperfusion injury via the ZEB1/LIF axis. Journal of cellular and molecular medicine. 2020 11; 24(22):13196-13207. doi: 10.1111/jcmm.15929. [PMID: 32996684]
  • Douglas J Eleveld, Pieter Colin, Anthony R Absalom, Michel M R F Struys. Target-controlled-infusion models for remifentanil dosing consistent with approved recommendations. British journal of anaesthesia. 2020 10; 125(4):483-491. doi: 10.1016/j.bja.2020.05.051. [PMID: 32654750]
  • Yi-Heng Liu, Xiao-Bing Hu, Xia-Min Yang, Ying-Wei Wang, Meng Deng. Comparing remifentanil and sufentanil in stress reduction during neurosurgery: a randomised controlled trial. International journal of clinical pharmacy. 2020 Oct; 42(5):1326-1334. doi: 10.1007/s11096-020-01094-1. [PMID: 32686050]
  • Matthew Stewart, Adam Thaler, Patrick Hunt, Leonard Estephan, Maurits Boon, Colin Huntley. Preferential use of total intravenous anesthesia in ambulatory otolaryngology surgery during the COVID-19 pandemic. American journal of otolaryngology. 2020 Sep; 41(5):102570. doi: 10.1016/j.amjoto.2020.102570. [PMID: 32505994]
  • Dirk J Bosch, Matijs V Meurs, Rianne M Jongman, Peter Heeringa, Wayel H Abdulahad, Michel M R F Struys. Effects of propofol and dexmedetomidine with and without remifentanil on serum cytokine concentrations in healthy volunteers: a post hoc analysis. British journal of anaesthesia. 2020 09; 125(3):267-274. doi: 10.1016/j.bja.2020.05.039. [PMID: 32660717]
  • Laura N Hannivoort, Anthony R Absalom, Michel M R F Struys. The role of pharmacokinetics and pharmacodynamics in clinical anaesthesia practice. Current opinion in anaesthesiology. 2020 Aug; 33(4):483-489. doi: 10.1097/aco.0000000000000881. [PMID: 32530894]
  • Kohei Fukuta, Asuka Kasai, Noriko Niki, Yuki Ishikawa, Ryosuke Kawanishi, Nami Kakuta, Yoko Sakai, Yasuo M Tsutsumi, Katsuya Tanaka. The effect of 1\% glucose loading on metabolism in the elderly patients during remifentanil-induced anesthesia: a randomized controlled trial. BMC anesthesiology. 2020 06; 20(1):143. doi: 10.1186/s12871-020-01061-3. [PMID: 32505171]
  • Gonul Sagiroglu, Ayse Baysal. Continuous intravenous versus intermittent bolus midazolam with remifentanil during arteriovenous fistula placement with monitored anesthesia care in chronic renal failure patients: a randomized controlled trial. Annals of Saudi medicine. 2020 May; 40(3):175-182. doi: 10.5144/0256-4947.2020.175. [PMID: 32493052]
  • Sang Hwan Ji, Ji Hyun Lee, Joo Youn Cho, Hwa Suk Kim, Young Eun Jang, Eun Hee Kim, Jin Tae Kim, Hee Soo Kim. External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old. Journal of Korean medical science. 2020 03; 35(11):e70. doi: 10.3346/jkms.2020.35.e70. [PMID: 32193901]
  • Egidijus Semenas, Maria Lönnemark, Pär Dahlman, Michael Hultström, Mats Eriksson. Analgesic effects of dexmedetomidine and remifentanil on periprocedural pain during percutaneous ablation of renal carcinoma. Upsala journal of medical sciences. 2020 Feb; 125(1):52-57. doi: 10.1080/03009734.2020.1720047. [PMID: 32067572]
  • Jungchan Park, Seung-Hwa Lee, Jong-Hwan Lee, Jeong Jin Min, Ji-Hye Kwon, Ah-Ran Oh, Keumhee Carriere, Joonghyun Ahn. Volatile versus total intravenous anesthesia for 30-day mortality following non-cardiac surgery in patients with preoperative myocardial injury. PloS one. 2020; 15(9):e0238661. doi: 10.1371/journal.pone.0238661. [PMID: 32915840]
  • Marija S Kutlesic, Gordana Kocic, Ranko M Kutlesic. [The effects of remifentanil used during cesarean section on oxidative stress markers in correlation with maternal hemodynamics and neonatal outcome: a randomized controlled trial]. Brazilian journal of anesthesiology (Elsevier). 2019 Nov; 69(6):537-545. doi: 10.1016/j.bjan.2019.05.005. [PMID: 31796304]
  • Ru Ouyang, Haijing Ren, Wei Liu, Xi Yuan, Enjun Lei. Remifentanil inhibits the traumatic stress response in emergent trauma surgery. Journal of clinical laboratory analysis. 2019 Oct; 33(8):e22971. doi: 10.1002/jcla.22971. [PMID: 31373418]
  • Brian J Anderson, Oliver Bagshaw. Practicalities of Total Intravenous Anesthesia and Target-controlled Infusion in Children. Anesthesiology. 2019 07; 131(1):164-185. doi: 10.1097/aln.0000000000002657. [PMID: 30920966]
  • Michael C Montana, Lindsay Juriga, Anshuman Sharma, Evan D Kharasch. Opioid Sensitivity in Children with and without Obstructive Sleep Apnea. Anesthesiology. 2019 06; 130(6):936-945. doi: 10.1097/aln.0000000000002664. [PMID: 30870164]
  • Heleen J Blussé van Oud-Alblas, Margreke J E Brill, Mariska Y M Peeters, Dick Tibboel, Meindert Danhof, Catherijne A J Knibbe. Population pharmacokinetic-pharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: a study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints. BMC anesthesiology. 2019 01; 19(1):15. doi: 10.1186/s12871-019-0684-z. [PMID: 30669968]
  • Qiang Jia, Fen Tian, Wei-Na Duan, Yi-Fan Jia, Hua-Xin Wang, Zhong-Yuan Xia. Effects of Dezocine-Remifentanil Intravenous Anaesthesia on Perioperative Signs, Serum TNF-&aipha; and IL-6 in Liver Cancer Patients undergoing Radiofrequency Ablation. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. 2019 Jan; 29(1):4-7. doi: 10.29271/jcpsp.2019.01.4. [PMID: 30630559]
  • Suchun Ding, Hongzhong Ma, Gao Wang, Zhenyu Yu, Kezhong Li, Aijie Huang. Effect of Remifentanil Combined Anesthesia on Cytokines and Oxidative Stress in Patients undergoing Laparoscopic Surgery for Colon Cancer. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. 2019 Jan; 29(1):8-11. doi: 10.29271/jcpsp.2019.01.8. [PMID: 30630560]
  • Mohamed R El-Tahan, Samah El Kenany, Ehsan M Abdelaty, Eiad A Ramzy. Comparison of the effects of low doses of dexmedetomidine and remifentanil on the maternal hemodynamic changes during caesarean delivery in patients with severe preeclampsia: a randomized trial. Minerva anestesiologica. 2018 12; 84(12):1343-1351. doi: 10.23736/s0375-9393.18.12312-1. [PMID: 29516705]
  • J Li, H-P Hu, Y Li, W Shao, J-Z Zhang, L-M Wang. Influences of remifentanil on myocardial ischemia-reperfusion injury and the expressions of Bax and Bcl-2 in rats. European review for medical and pharmacological sciences. 2018 12; 22(24):8951-8960. doi: 10.26355/eurrev_201812_16665. [PMID: 30575939]
  • Mohamed Said Nakhli, Mohamed Kahloul, Taieb Guizani, Chekib Zedini, Ajmi Chaouch, Walid Naija. Intravenous lidocaine as adjuvant to general anesthesia in renal surgery. The Libyan journal of medicine. 2018 Dec; 13(1):1433418. doi: 10.1080/19932820.2018.1433418. [PMID: 29433385]
  • Ping-Chen, Qing-Song Lin, Xian-Zhong Lin. Optimal concentration of the transversus abdominis plane block in enhanced recovery after surgery protocols for patients of advanced age undergoing laparoscopic rectal cancer surgery. The Journal of international medical research. 2018 Nov; 46(11):4437-4446. doi: 10.1177/0300060518790699. [PMID: 30111216]
  • Daan J Reesink, J M W Scheltema, M M Barendrecht, A E Boeken Kruger, A Jansonius, J Wiltink, F van der Windt. Extracorporeal shock wave lithotripsy under intravenous sedation for treatment of urolithiasis. Scandinavian journal of urology. 2018 Oct; 52(5-6):453-458. doi: 10.1080/21681805.2018.1524398. [PMID: 30451054]
  • Shigeru Maeda, Tsugunobu Andoh, Rieko Onishi, Yumiko Tomoyasu, Hitoshi Higuchi, Takuya Miyawaki. Remifentanil suppresses increase in interleukin-6 mRNA in the brain by inhibiting cyclic AMP synthesis. Journal of anesthesia. 2018 10; 32(5):731-739. doi: 10.1007/s00540-018-2548-y. [PMID: 30167784]
  • Monica Simeoni, Chao Chen. Population Pharmacokinetic Modelling for Estimation of Remifentanil Metabolic-Ratio Using Non-steady-State Concentrations under Rapidly Adaptive Dosing. Pharmaceutical research. 2018 Sep; 35(11):216. doi: 10.1007/s11095-018-2508-0. [PMID: 30255401]
  • Tao Yan, Guo-Hua Zhang, Bao-Na Wang, Li Sun, Hui Zheng. Effects of propofol/remifentanil-based total intravenous anesthesia versus sevoflurane-based inhalational anesthesia on the release of VEGF-C and TGF-β and prognosis after breast cancer surgery: a prospective, randomized and controlled study. BMC anesthesiology. 2018 09; 18(1):131. doi: 10.1186/s12871-018-0588-3. [PMID: 30243294]
  • Hélène I Morue, Shalini Raj-Lawrence, Sarah Saxena, Anne Delbaere, Edgard Engelman, Luc A Barvais. Placebo versus low-dose ketamine infusion in addition to remifentanil target-controlled infusion for conscious sedation during oocyte retrieval: A double-blinded, randomised controlled trial. European journal of anaesthesiology. 2018 09; 35(9):667-674. doi: 10.1097/eja.0000000000000826. [PMID: 29757924]
  • Luis I Cortínez, Brian J Anderson. Advances in pharmacokinetic modeling: target controlled infusions in the obese. Current opinion in anaesthesiology. 2018 Aug; 31(4):415-422. doi: 10.1097/aco.0000000000000619. [PMID: 29794852]
  • Wataru Sakai, Yusuke Yoshikawa, Michiaki Yamakage. In reply: Why remifentanil?. Journal of anesthesia. 2018 06; 32(3):459. doi: 10.1007/s00540-018-2487-7. [PMID: 29616346]
  • Guillermo Lema. …why remifentanil?. Journal of anesthesia. 2018 06; 32(3):458. doi: 10.1007/s00540-018-2488-6. [PMID: 29594514]
  • Seokha Yoo, Karam Nam, Won Ho Kim. Association between remifentanil and acute kidney injury. Journal of anesthesia. 2018 04; 32(2):306. doi: 10.1007/s00540-018-2450-7. [PMID: 29327277]
  • L-Q Ren, X-X Sun, Y Guan. Effects of sevoflurane or propofol combined with remifentanil anesthesia on clinical efficacy and stress response in pregnant women with pregnancy-induced hypertension. European review for medical and pharmacological sciences. 2018 03; 22(6):1825-1829. doi: 10.26355/eurrev_201803_14602. [PMID: 29630132]
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