Cinnamic acid (BioDeep_00000014351)

Main id: BioDeep_00000270977

 

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 natural product


代谢物信息卡片


cinnamic acid, 14C-labeled cpd (E)-isomer

化学式: C9H8O2 (148.0524)
中文名称: 反式肉桂酸, 肉桂酸, 別桂皮酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(/C=C/C(=O)O)ccccc1
InChI: InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+

描述信息

Cinnamic acid, also known as (Z)-cinnamate or 3-phenyl-acrylate, belongs to the class of organic compounds known as cinnamic acids. These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Cinnamic acid can be obtained from oil of cinnamon, or from balsams such as storax. Cinnamic acid is a weakly acidic compound (based on its pKa). It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Cinnamic acid exists in all living organisms, ranging from bacteria to plants to humans. Outside of the human body, cinnamic acid has been detected, but not quantified in, chinese cinnamons. In plants, cinnamic acid is a central intermediate in the biosynthesis of myriad natural products include lignols (precursors to lignin and lignocellulose), flavonoids, isoflavonoids, coumarins, aurones, stilbenes, catechin, and phenylpropanoids.
CONFIDENCE standard compound; INTERNAL_ID 191; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3778; ORIGINAL_PRECURSOR_SCAN_NO 3776
CONFIDENCE standard compound; INTERNAL_ID 191; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3783; ORIGINAL_PRECURSOR_SCAN_NO 3781
Cinnamic acid is a white crystalline hydroxycinnamic acid, which is slightly soluble in water. It is obtained from oil of cinnamon, or from balsams such as storax. cis-Cinnamic acid is found in chinese cinnamon.
CONFIDENCE standard compound; INTERNAL_ID 183
Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[1].
trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[1].

同义名列表

76 个代谢物同义名

cinnamic acid, 14C-labeled cpd (E)-isomer; cinnamic acid, 3H-labeled cpd (Z)-isomer; cinnamic acid, 3H-labeled cpd (E)-isomer; (E)-cinnamic acid, 2-(14)C-labeled cpd; cinnamic acid, sodium salt(Z)-isomer; cinnamic acid, sodium salt(E)-isomer; cinnamic acid, zinc salt(E)-isomer; cinnamic acid, 2-(13)C-labeled cpd; cinnamic acid, 2-(14)C-labeled cpd; cinnamic acid, 1-(13)C-labeled cpd; cinnamic acid, 3-(14)C-labeled cpd; tritium labeled (Z)-cinnamic acid; cinnamic acid, ion(1-)-(E)-isomer; cinnamic acid, (trans)-(E)-isomer; tritium labeled (E)-cinnamic acid; cinnamic acid, 1-14C-labeled cpd; cinnamic acid, nickel (+2) salt; cinnamic acid, 13C-labeled cpd; cinnamic acid, radical ion(1-); (2Z)-3-Phenyl-2-propenoic acid; (2Z)-3-phenylprop-2-enoic acid; cinnamic acid, 14C-labeled cpd; cinnamic acid, potassium salt; (E)-3-Phenyl-2-propenoic acid; (Z)-3-Phenyl-2-propenoic acid; cinnamic acid, sodium salt; (2Z)-3-Phenyl-2-propenoate; 3-Phenyl-2-propenoic acid; (e)-3-Phenyl-2-propenoate; cinnamic acid, (Z)-isomer; (Z)-3-Phenyl-2-propenoate; (2Z)-3-Phenylacrylic acid; (Z)-3-Phenylacrylic acid; .beta-Phenylacrylic acid; cis-beta-Carboxystyrene; beta-Phenylacrylic acid; cinnamic acid, ion(1-); Benzylideneacetic acid; 3-Phenylpropenoic acid; 3-Phenyl-2-propenoate; 3-Phenyl-acrylic acid; (2Z)-3-Phenylacrylate; Benzenepropenoic acid; cis-Β-carboxystyrene; 3-Phenylacrylic acid; cis-b-Carboxystyrene; Β-phenylacrylic acid; Benzeneacrylic acid; trans-cinnamic acid; Phenylacrylic acid; 3-Phenylpropenoate; cis-cinnamic acid; 3-Phenyl-acrylate; (E)-Cinnamic acid; E-Z cinnamic acid; (Z)-Cinnamic acid; Allocinnamic acid; Benzenepropenoate; 3-Phenylacrylate; Isocinnamic acid; sodium cinnamate; Z-Cinnamic acid; Cinnamylic acid; trans-Cinnamate; E-cinnamic acid; Phenylacrylate; cis-Zimtsaeure; cis-Cinnamate; (Z)-Cinnamate; Cinnamic Acid; cinnamate; Cinnamic acid; trans-3-Phenylacrylic acid; Cinnamic acid; trans-Cinnamate; trans-Cinnamic acid



数据库引用编号

38 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

623 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Menglu Wu, Zi-An Deng, Chaoyi Shen, Zhichao Yang, Zihan Cai, Di Wu, Kunsong Chen. Fabrication of antimicrobial PCL/EC nanofibrous films containing natamycin and trans-cinnamic acid by microfluidic blow spinning for fruit preservation. Food chemistry. 2024 Jun; 442(?):138436. doi: 10.1016/j.foodchem.2024.138436. [PMID: 38244441]
  • Rong Fan, Zining Liang, Qing Wang, Sizhe Chen, Shiting Huang, Jiansu Liu, Rui Huang, Jie Chen, Feilan Zhao, Wei Huang. Beneficial action of cinnamic acid against ovarian cancer via network pharmacology analysis and the pharmacological activity assessment. Naunyn-Schmiedeberg's archives of pharmacology. 2024 05; 397(5):2987-2994. doi: 10.1007/s00210-023-02766-1. [PMID: 37870582]
  • Micheli Negri Brusamarello, Antonio Pedro Brusamarello, Mário Antônio Alves da Cunha, Cleverson Busso. Biological and phytochemical potential of Baccharis trimera (Less.) DC leaf extract on swine clinical isolates. Natural product research. 2024 May; 38(10):1799-1805. doi: 10.1080/14786419.2023.2222217. [PMID: 37292020]
  • Yanan Lu, Xue Han. Therapeutic Implications of Phenolic Acids for Ameliorating Inflammatory Bowel Disease. Nutrients. 2024 Apr; 16(9):. doi: 10.3390/nu16091347. [PMID: 38732594]
  • Tarun Kumar Kar, Sananda Sil, Angshita Ghosh, Ananya Barman, Sandip Chattopadhyay. Mitigation of letrozole induced polycystic ovarian syndrome associated inflammatory response and endocrinal dysfunction by Vitex negundo seeds. Journal of ovarian research. 2024 Apr; 17(1):76. doi: 10.1186/s13048-024-01378-4. [PMID: 38589892]
  • O V Ravikumar, Vanitha Marunganathan, Meenakshi Sundaram Kishore Kumar, Magesh Mohan, Mohammed Rafi Shaik, Baji Shaik, Ajay Guru, Khairiyah Mat. Zinc oxide nanoparticles functionalized with cinnamic acid for targeting dental pathogens receptor and modulating apoptotic genes in human oral epidermal carcinoma KB cells. Molecular biology reports. 2024 Feb; 51(1):352. doi: 10.1007/s11033-024-09289-9. [PMID: 38400866]
  • Hanru Liu, Chonglin Cai, Xingjia Zhang, Wenkui Li, Zhiqing Ma, Juntao Feng, Xili Liu, Peng Lei. Discovery of Novel Cinnamic Acid Derivatives as Fungicide Candidates. Journal of agricultural and food chemistry. 2024 Feb; 72(5):2492-2500. doi: 10.1021/acs.jafc.3c05655. [PMID: 38271672]
  • Fábio Florença Cardoso, Guilherme Henrique Marchi Salvador, Walter Luís Garrido Cavalcante, Maeli Dal-Pai, Marcos Roberto de Mattos Fontes. BthTX-I, a phospholipase A2-like toxin, is inhibited by the plant cinnamic acid derivative: chlorogenic acid. Biochimica et biophysica acta. Proteins and proteomics. 2024 02; 1872(2):140988. doi: 10.1016/j.bbapap.2023.140988. [PMID: 38142025]
  • Baoyun Shan, Jian Mo, Jiayi Yang, Xiaochun Qin, Haina Yu. Cloning and functional characterization of a cinnamate 4-hydroxylase gene from the hornwort Anthoceros angustus. Plant science : an international journal of experimental plant biology. 2024 Jan; 341(?):111989. doi: 10.1016/j.plantsci.2024.111989. [PMID: 38232819]
  • Runqin Wang, Xueling Zhang, Xiangyu Meng, Li Yang, Rongrong Xing, Xuan Chen, Shuang Hu. Hydroxyl-rich ferrofluid for efficient liquid phase microextraction of cinnamic acid derivatives in traditional Chinese medicine. Journal of separation science. 2024 Jan; 47(1):e2300796. doi: 10.1002/jssc.202300796. [PMID: 38234030]
  • Mariza Severina de Lima Silva, Marcilene Souza da Silva, Rômulo Carlos Dantas da Cruz, Bruno de Oliveira Veras, Ivone Antonia de Souza, Rafael Matos Ximenes, Thiago Mendonça de Aquino, Alexandre José da Silva Góes. Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae). Experimental parasitology. 2024 Jan; 256(?):108657. doi: 10.1016/j.exppara.2023.108657. [PMID: 38043764]
  • Yao Zhao, Jitao Hu, Yilin Zhang, Han Tao, Linying Li, Yuqing He, Xueying Zhang, Chi Zhang, Gaojie Hong. Unveiling targeted spatial metabolome of rice seed at the dough stage using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry imaging. Food research international (Ottawa, Ont.). 2023 Dec; 174(Pt 1):113578. doi: 10.1016/j.foodres.2023.113578. [PMID: 37986446]
  • Agata Wilczańska, Barbara Sparzak-Stefanowska, Adam Kokotkiewicz, Anna Jesionek, Aleksandra Królicka, Maria Łuczkiewicz, Mirosława Krauze-Baranowska. Biotechnological strategies for controlled accumulation of flavones in hairy root culture of Scutellaria lateriflora L. Scientific reports. 2023 11; 13(1):20422. doi: 10.1038/s41598-023-47757-7. [PMID: 37990031]
  • Xiaoxue Li, Yue Hu, Bingxin He, Lingyu Li, Yu Tian, Yingjie Xiao, Hai Shang, Zhongmei Zou. Design, synthesis and evaluation of ursodeoxycholic acid-cinnamic acid hybrids as potential anti-inflammatory agents by inhibiting Akt/NF-κB and MAPK signaling pathways. European journal of medicinal chemistry. 2023 Nov; 260(?):115785. doi: 10.1016/j.ejmech.2023.115785. [PMID: 37678142]
  • Fangping Zhong, Qi Zhang, Kejia Chen, Shichao Lan, Wenchao Yang, Xiuhai Gan. Eco-Friendly Cinnamic Acid Derivatives Containing Glycoside Scaffolds as Potential Antiviral Agents. Journal of agricultural and food chemistry. 2023 Nov; ?(?):. doi: 10.1021/acs.jafc.3c06318. [PMID: 37943715]
  • Yu Shi, Lan-Tu Xiong, Hui Li, Wen-Long Li, Dylan O'Neill Rothenberg, Li-Sheng Liao, Xin Deng, Gao-Peng Song, Zi-Ning Cui. Derivative of cinnamic acid inhibits T3SS of Xanthomonas oryzae pv. oryzae through the HrpG-HrpX regulatory cascade. Bioorganic chemistry. 2023 Sep; 141(?):106871. doi: 10.1016/j.bioorg.2023.106871. [PMID: 37734193]
  • Farkhondeh Safari, Hamid Hassanpour, Ahmad Alijanpour. Evaluation of hackberry (Celtis australis L.) fruits as sources of bioactive compounds. Scientific reports. 2023 07; 13(1):12233. doi: 10.1038/s41598-023-39421-x. [PMID: 37507445]
  • Yimeng Cui, Peiwei Wang, Mengli Li, Yujue Wang, Xinmiao Tang, Jingang Cui, Yu Chen, Teng Zhang. Cinnamic acid mitigates left ventricular hypertrophy and heart failure in part through modulating FTO-dependent N6-methyladenosine RNA modification in cardiomyocytes. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Jul; 165(?):115168. doi: 10.1016/j.biopha.2023.115168. [PMID: 37453198]
  • Giuseppe Di Pede, Pedro Mena, Letizia Bresciani, Mariem Achour, Rosa Mª Lamuela, Ramón Estruch, Rikard Landberg, Sabine E Kulling, David Wishart, Ana Rodriguez-Mateos, Michael N Clifford, Alan Crozier, Claudine Manach, Daniele Del Rio. A systematic review and comprehensive evaluation of human intervention studies to unravel the bioavailability of hydroxycinnamic acids. Antioxidants & redox signaling. 2023 Jun; ?(?):. doi: 10.1089/ars.2023.0254. [PMID: 37382416]
  • Kateryna Kukil, Elias Englund, Nick Crang, Elton P Hudson, Pia Lindberg. Laboratory evolution of Synechocystis PCC6803 for phenylpropanoid production. Metabolic engineering. 2023 Jun; ?(?):. doi: 10.1016/j.ymben.2023.06.014. [PMID: 37392984]
  • Zühal Bayrakçeken Güven, Iclal Saracoglu, Akito Nagatsu, Mustafa Abdullah Yilmaz, A Ahmet Basaran. Anti-tyrosinase and antimelanogenic effect of cinnamic acid derivatives from Prunus mahaleb L.: Phenolic composition, isolation, identification and inhibitory activity. Journal of ethnopharmacology. 2023 Jun; 310(?):116378. doi: 10.1016/j.jep.2023.116378. [PMID: 36924865]
  • Aline Costa Santos, Felipe Akihiro Melo Otsuka, Rodrigo Brito Santos, Danielle de Jesus Trindade, Humberto Reis Matos. Antiglycation potential and antioxidant activity of genipap (Genipa americana L.) in oxidative stress mediated by hydrogen peroxide on cell culture. Natural product research. 2023 Jun; 37(12):2065-2069. doi: 10.1080/14786419.2022.2116700. [PMID: 36093565]
  • Nariman E Mahdy, Passent M Abdel-Baki, Ahmed A El-Rashedy, Rana M Ibrahim. Modulatory Effect of Pyrus pyrifolia Fruit and its Phenolics on Key Enzymes against Metabolic Syndrome: Bioassay-Guided Approach, HPLC Analysis, and In Silico Study. Plant foods for human nutrition (Dordrecht, Netherlands). 2023 May; ?(?):. doi: 10.1007/s11130-023-01069-3. [PMID: 37219720]
  • Abdullah Mashraqi, Yosra Modafer, Mohamed A Al Abboud, Hanaa M Salama, Emad Abada. HPLC Analysis and Molecular Docking Study of Myoporum serratum Seeds Extract with Its Bioactivity against Pathogenic Microorganisms and Cancer Cell Lines. Molecules (Basel, Switzerland). 2023 May; 28(10):. doi: 10.3390/molecules28104041. [PMID: 37241781]
  • M Amundsen, L Jaakola, K Aaby, I Martinussen, N Kelanne, S Tuominen, O Laaksonen, B Yang, A L Hykkerud. Effect of ripening temperature on the chemical composition of lingonberries (Vaccinium vitis-idaea L.) of northern and southern origin. Food research international (Ottawa, Ont.). 2023 05; 167(?):112738. doi: 10.1016/j.foodres.2023.112738. [PMID: 37087220]
  • Yusen Shen, Jiansheng Wang, Ranjan K Shaw, Xiaoguang Sheng, Huifang Yu, Ferdinando Branca, Honghui Gu. Comparative Transcriptome and Targeted Metabolome Profiling Unravel the Key Role of Phenylpropanoid and Glucosinolate Pathways in Defense against Alternaria brassicicola in Broccoli. Journal of agricultural and food chemistry. 2023 Apr; 71(16):6499-6510. doi: 10.1021/acs.jafc.2c08486. [PMID: 37061924]
  • Pengdong Xie, Yangyang Yang, William Oyom, Tingting Su, Yingbo Tang, Yi Wang, Yongcai Li, Dov Prusky, Yang Bi. Chitooligosaccharide accelerated wound healing in potato tubers by promoting the deposition of suberin polyphenols and lignin at wounds. Plant physiology and biochemistry : PPB. 2023 Apr; 199(?):107714. doi: 10.1016/j.plaphy.2023.107714. [PMID: 37119550]
  • Anita Bułakowska, Jarosław Sławiński, Rafał Hałasa, Anna Hering, Magdalena Gucwa, J Renata Ochocka, Justyna Stefanowicz-Hajduk. An In Vitro Antimicrobial, Anticancer and Antioxidant Activity of N-[(2-Arylmethylthio)phenylsulfonyl]cinnamamide Derivatives. Molecules (Basel, Switzerland). 2023 Mar; 28(7):. doi: 10.3390/molecules28073087. [PMID: 37049849]
  • Linmei Deng, Lifen Luo, Yue Li, Luotao Wang, Junxing Zhang, Bianxian Zi, Chen Ye, Yixiang Liu, Huichuan Huang, Xinyue Mei, Weiping Deng, Xiahong He, Shusheng Zhu, Min Yang. Autotoxic Ginsenoside Stress Induces Changes in Root Exudates to Recruit the Beneficial Burkholderia Strain B36 as Revealed by Transcriptomic and Metabolomic Approaches. Journal of agricultural and food chemistry. 2023 Mar; 71(11):4536-4549. doi: 10.1021/acs.jafc.3c00311. [PMID: 36893094]
  • Bin-Xin Yang, Zhen-Xing Li, Shuai-Shuai Liu, Jie Yang, Pei-Yi Wang, Hong-Wu Liu, Xiang Zhou, Li-Wei Liu, Zhi-Bing Wu, Song Yang. Novel cinnamic acid derivatives as a versatile tool for developing agrochemicals for controlling plant virus and bacterial diseases by enhancing plant defense responses. Pest management science. 2023 Mar; ?(?):. doi: 10.1002/ps.7433. [PMID: 36864774]
  • Yumin Cao, Ning Zhou, Tong Liu, Jinying Zhang, Yongxiang Wang, Bingxian Zhang, Zhenkai Zhang, Weisheng Feng, Xiaoke Zheng. Comparative pharmacokinetic studies of Ephedra herba in common cold and nephrotic syndrome rat models. Journal of separation science. 2023 Feb; ?(?):e2200895. doi: 10.1002/jssc.202200895. [PMID: 36823773]
  • Junying Ma, Xiaoyan Li, Maolin He, Yanwen Li, Wei Lu, Mengyao Li, Bo Sun, Yangxia Zheng. A Joint Transcriptomic and Metabolomic Analysis Reveals the Regulation of Shading on Lignin Biosynthesis in Asparagus. International journal of molecular sciences. 2023 Jan; 24(2):. doi: 10.3390/ijms24021539. [PMID: 36675053]
  • Praveen Khatri, Ling Chen, Istvan Rajcan, Sangeeta Dhaubhadel. Functional characterization of Cinnamate 4-hydroxylase gene family in soybean (Glycine max). PloS one. 2023; 18(5):e0285698. doi: 10.1371/journal.pone.0285698. [PMID: 37186600]
  • Jahir Antonio Barajas-Ramírez, Angel Humberto Cabrera-Ramírez, Victoria Guadalupe Aguilar-Raymundo. Antioxidant Activity, Total Phenolic, Tannin, and Flavonoid Content of Five Plants Used in Traditional Medicine in Penjamo, Guanajuato. Chemistry & biodiversity. 2023 Jan; 20(1):e202200834. doi: 10.1002/cbdv.202200834. [PMID: 36447306]
  • Rayudika Aprilia Patindra Purba, Pramote Paengkoum. Exploring the Phytochemical Profiles and Antioxidant, Antidiabetic, and Antihemolytic Properties of Sauropus androgynus Dried Leaf Extracts for Ruminant Health and Production. Molecules (Basel, Switzerland). 2022 Dec; 27(23):. doi: 10.3390/molecules27238580. [PMID: 36500671]
  • Rongfei Lu, Jianwei Xu, Zhen Wang, Shaoyong Zhang, Hailong Wang, Hui Xu, Min Lv. Semisynthesis and Pesticidal Activities of Novel Cholesterol Ester Derivatives Containing Cinnamic Acid-like Fragments. Molecules (Basel, Switzerland). 2022 Dec; 27(23):. doi: 10.3390/molecules27238437. [PMID: 36500528]
  • Anupama Nair, M R Preetha Rani, Palayyan Salin Raj, S Ranjit, K Rajankutty, K G Raghu. Cinnamic acid is beneficial to diabetic cardiomyopathy via its cardioprotective, anti-inflammatory, anti-dyslipidemia, and antidiabetic properties. Journal of biochemical and molecular toxicology. 2022 Dec; 36(12):e23215. doi: 10.1002/jbt.23215. [PMID: 36117386]
  • Liangfeng Liu, Huai Chen, Yixin He, Jianliang Liu, Xue Dan, Lin Jiang, Wei Zhan. Carbon stock stability in drained peatland after simulated plant carbon addition: Strong dependence on deeper soil. The Science of the total environment. 2022 Nov; 848(?):157539. doi: 10.1016/j.scitotenv.2022.157539. [PMID: 35908690]
  • Wenhao Yang, Yu Li, Qian Zhao, Yuting Guo, Yan Dong. Intercropping alleviated the phytotoxic effects of cinnamic acid on the root cell wall structural resistance of faba bean and reduced the occurrence of Fusarium wilt. Physiologia plantarum. 2022 Nov; 174(6):e13827. doi: 10.1111/ppl.13827. [PMID: 36403196]
  • Javier A G Vanegas, Horácio B Pacule, Rebeca M Capitão, Carlos R D Correia, Willian C Terra, Vicente P Campos, Denilson F Oliveira. Methyl Esters of (E)-Cinnamic Acid: Activity against the Plant-Parasitic Nematode Meloidogyne incognita and In Silico Interaction with Histone Deacetylase. Journal of agricultural and food chemistry. 2022 Jun; 70(22):6624-6633. doi: 10.1021/acs.jafc.1c08142. [PMID: 35622462]
  • Yin-Peng Bai, Cheng-Jie Yang, Nan Deng, Mi Zhang, Zhi-Jun Zhang, Lei Li, Yong Zhou, Xiong-Fei Luo, Chuan-Rui Xu, Bao-Qi Zhang, Yue Ma, Ying-Qian Liu. Design and synthesis of novel 7-ethyl-10-fluoro-20-O-(cinnamic acid ester)-camptothecin derivatives as potential high selectivity and low toxicity topoisomerase I inhibitors for hepatocellular carcinoma. Biochemical pharmacology. 2022 06; 200(?):115049. doi: 10.1016/j.bcp.2022.115049. [PMID: 35469784]
  • Fei Luan, Zhili Rao, Lixia Peng, Ziqin Lei, Jiuseng Zeng, Xi Peng, Ruocong Yang, Rong Liu, Nan Zeng. Cinnamic acid preserves against myocardial ischemia/reperfusion injury via suppression of NLRP3/Caspase-1/GSDMD signaling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Jun; 100(?):154047. doi: 10.1016/j.phymed.2022.154047. [PMID: 35320770]
  • Cheng Chen. Anti-atherosclerotic Activity of Para Methoxy Cinnamic Acid in High Fat Diet Induced Hyperlipidemia Model Rats. Applied biochemistry and biotechnology. 2022 May; 194(5):1911-1924. doi: 10.1007/s12010-021-03735-1. [PMID: 34997446]
  • Ayako Kusakabe, Chen Wang, Ya-Ming Xu, István Molnár, S Patricia Stock. Selective Toxicity of Secondary Metabolites from the Entomopathogenic Bacterium Photorhabdus luminescens sonorensis against Selected Plant Parasitic Nematodes of the Tylenchina Suborder. Microbiology spectrum. 2022 02; 10(1):e0257721. doi: 10.1128/spectrum.02577-21. [PMID: 35138171]
  • Kateryna Kukil, Pia Lindberg. Expression of phenylalanine ammonia lyases in Synechocystis sp. PCC 6803 and subsequent improvements of sustainable production of phenylpropanoids. Microbial cell factories. 2022 Jan; 21(1):8. doi: 10.1186/s12934-021-01735-8. [PMID: 35012528]
  • Xuemei Xiao, Ju Li, Jian Lyu, Linli Hu, Yue Wu, Zhongqi Tang, Jihua Yu, Alejandro Calderón-Urrea. Grafting-enhanced tolerance of cucumber to toxic stress is associated with regulation of phenolic and other aromatic acids metabolism. PeerJ. 2022; 10(?):e13521. doi: 10.7717/peerj.13521. [PMID: 35669966]
  • Weijie Li, Kexin Wang, Yudong Liu, Hao Wu, Yan He, Congchong Li, Qian Wang, Xiaohui Su, Shikai Yan, Weiwei Su, Yanqiong Zhang, Na Lin. A Novel Drug Combination of Mangiferin and Cinnamic Acid Alleviates Rheumatoid Arthritis by Inhibiting TLR4/NFκB/NLRP3 Activation-Induced Pyroptosis. Frontiers in immunology. 2022; 13(?):912933. doi: 10.3389/fimmu.2022.912933. [PMID: 35799788]
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