Dibenz[a,c]anthracene (BioDeep_00000012805)

 

Secondary id: BioDeep_00001868600

human metabolite blood metabolite


代谢物信息卡片


pentacyclo[12.8.0.0^{2,7}.0^{8,13}.0^{16,21}]docosa-1(22),2,4,6,8,10,12,14,16,18,20-undecaene

化学式: C22H14 (278.1095)
中文名称: 二苯并[a,c]蒽
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: C1=CC=C2C=C3C4=CC=CC=C4C4=CC=CC=C4C3=CC2=C1
InChI: InChI=1S/C22H14/c1-2-8-16-14-22-20-12-6-4-10-18(20)17-9-3-5-11-19(17)21(22)13-15(16)7-1/h1-14H



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AHR, AHRR, ARNT, CYP1A1, HPGDS, PRKX
Peripheral membrane protein 3 CYP1A1, CYP1B1, PPOX
Endoplasmic reticulum membrane 4 CYP1A1, CYP1A2, CYP1B1, HSP90B1
Nucleus 6 AHR, AHRR, ARNT, HSP90B1, NAP1L2, PRKX
cytosol 4 AHR, AHRR, HPGDS, HSP90B1
mitochondrial membrane 1 PPOX
nuclear body 1 ARNT
nucleoplasm 5 AHR, AHRR, ARNT, HPGDS, PRKX
RNA polymerase II transcription regulator complex 1 ARNT
Multi-pass membrane protein 1 SLC45A2
Synapse 1 PPOX
mitochondrial inner membrane 2 CYP1A1, PPOX
postsynapse 1 PPOX
sarcolemma 1 SYNM
smooth endoplasmic reticulum 1 HSP90B1
synaptic vesicle 1 PPOX
Membrane 3 CYP1B1, HSP90B1, SLC45A2
extracellular exosome 1 HSP90B1
endoplasmic reticulum 1 HSP90B1
perinuclear region of cytoplasm 2 HSP90B1, PPOX
adherens junction 1 SYNM
mitochondrion 3 CYP1A1, CYP1B1, PPOX
protein-containing complex 2 AHR, HSP90B1
intracellular membrane-bounded organelle 4 CYP1A1, CYP1A2, CYP1B1, HPGDS
Microsome membrane 3 CYP1A1, CYP1A2, CYP1B1
extracellular region 2 HSP90B1, PPOX
transcription regulator complex 2 AHR, ARNT
neuronal dense core vesicle lumen 1 PPOX
cytoplasmic vesicle 1 PPOX
Melanosome membrane 1 SLC45A2
midbody 1 HSP90B1
Mitochondrion inner membrane 2 CYP1A1, PPOX
focal adhesion 1 HSP90B1
mitochondrial intermembrane space 1 PPOX
collagen-containing extracellular matrix 1 HSP90B1
intermediate filament 1 SYNM
chromatin 4 AHR, AHRR, ARNT, NAP1L2
aryl hydrocarbon receptor complex 3 AHR, AHRR, ARNT
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
intermediate filament cytoskeleton 1 SYNM
endoplasmic reticulum lumen 1 HSP90B1
Sarcoplasmic reticulum lumen 1 HSP90B1
costamere 1 SYNM
neurofilament cytoskeleton 1 SYNM
Rough endoplasmic reticulum 1 PPOX
Intermembrane side 1 PPOX
endocytic vesicle lumen 1 HSP90B1
endoplasmic reticulum chaperone complex 1 HSP90B1
nuclear aryl hydrocarbon receptor complex 2 AHR, ARNT
cytosolic aryl hydrocarbon receptor complex 1 AHR


文献列表

  • Olivier Pouns, Arturo Mangas, Rafael Coveñas, Michel Geffard. Circulating antibodies directed against "polycyclic aromatic hydrocarbon-like" structures in the sera of cancer patients. Cancer epidemiology. 2009 Jul; 33(1):3-8. doi: 10.1016/j.canep.2009.04.013. [PMID: 19679040]
  • Hugh A Barton, V James Cogliano, Lynn Flowers, Larry Valcovic, R Woodrow Setzer, Tracey J Woodruff. Assessing susceptibility from early-life exposure to carcinogens. Environmental health perspectives. 2005 Sep; 113(9):1125-33. doi: 10.1289/ehp.7667. [PMID: 16140616]