Physcion 8-glucoside (BioDeep_00000008063)

Main id: BioDeep_00000017595

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


1-Hydroxy-3-methoxy-6-methyl-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)anthracene-9,10-dione

化学式: C22H22O10 (446.1213)
中文名称: 大黄素甲醚-8-O-β-D-葡萄糖苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12C(=O)C3=C(C=C(C=C3O)C)C(=O)C=1C=C(C=C2O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)OC
InChI: InChI=1S/C22H22O10/c1-8-3-10-16(19(27)15-11(17(10)25)5-9(30-2)6-12(15)24)13(4-8)31-22-21(29)20(28)18(26)14(7-23)32-22/h3-6,14,18,20-24,26,28-29H,7H2,1-2H3



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

50 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 PIK3CA, RB1, RUNX2, STMN4
Peripheral membrane protein 1 GORASP1
Endoplasmic reticulum membrane 1 SGMS2
Nucleus 2 RB1, RUNX2
cytosol 3 PIK3CA, RB1, RUNX2
nucleoplasm 3 RB1, RUNX2, SGMS2
Cell membrane 3 SELP, SGMS2, TNF
Cytoplasmic side 1 GORASP1
lamellipodium 1 PIK3CA
Cell projection, axon 1 STMN4
Cell projection, growth cone 1 STMN4
Multi-pass membrane protein 1 SGMS2
Golgi apparatus membrane 2 GORASP1, SGMS2
cell surface 3 EPO, FGG, TNF
Golgi apparatus 3 GORASP1, SGMS2, STMN4
Golgi membrane 2 GORASP1, SGMS2
growth cone 1 STMN4
neuronal cell body 1 TNF
Lysosome 1 SGSH
plasma membrane 6 F2, FGG, PIK3CA, SELP, SGMS2, TNF
Membrane 1 SGMS2
extracellular exosome 6 BMP3, EPO, F2, FGG, SELP, SGSH
extracellular space 7 BMP3, EPO, F2, FGG, IL6, SELP, TNF
lysosomal lumen 1 SGSH
perinuclear region of cytoplasm 1 PIK3CA
intercalated disc 1 PIK3CA
Single-pass type I membrane protein 1 SELP
Secreted 6 BMP3, EPO, F2, FGG, IL6, SELP
extracellular region 7 BMP3, EPO, F2, FGG, IL6, SELP, TNF
transcription regulator complex 1 RUNX2
external side of plasma membrane 3 FGG, SELP, TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
spindle 1 RB1
cis-Golgi network 1 GORASP1
PML body 1 RB1
collagen-containing extracellular matrix 2 F2, FGG
neuron projection 1 STMN4
chromatin 2 RB1, RUNX2
phagocytic cup 1 TNF
blood microparticle 2 F2, FGG
cell body 1 EPO
platelet alpha granule 1 FGG
platelet dense granule membrane 1 SELP
secretory granule lumen 1 EPO
Golgi lumen 1 F2
endoplasmic reticulum lumen 3 F2, FGG, IL6
platelet alpha granule lumen 1 FGG
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
SWI/SNF complex 1 RB1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
platelet alpha granule membrane 1 SELP
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
fibrinogen complex 1 FGG
platelet dense granule lumen 1 SELP
interleukin-6 receptor complex 1 IL6
chromatin lock complex 1 RB1
Rb-E2F complex 1 RB1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Han-Lin Gong, Wen-Fu Tang, Qin Yu, Jin Xiang, Qing Xia, Guang-Yuan Chen, Xi Huang, Mao-Zhi Liang. Effect of severe acute pancreatitis on pharmacokinetics of Da-Cheng-Qi Decoction components. World journal of gastroenterology. 2009 Dec; 15(47):5992-9. doi: 10.3748/wjg.15.5992. [PMID: 20014465]
  • Liselotte Krenn, Armin Presser, Riddhi Pradhan, Beate Bahr, Dietrich H Paper, Klaus K Mayer, Brigitte Kopp. Sulfemodin 8-O-beta-D-glucoside, a new sulfated anthraquinone glycoside, and antioxidant phenolic compounds from Rheum emodi. Journal of natural products. 2003 Aug; 66(8):1107-9. doi: 10.1021/np0301442. [PMID: 12932135]
  • S S Huang, S F Yeh, C Y Hong. Effect of anthraquinone derivatives on lipid peroxidation in rat heart mitochondria: structure-activity relationship. Journal of natural products. 1995 Sep; 58(9):1365-71. doi: 10.1021/np50123a005. [PMID: 7494143]