3,3',4',7-Tetrahydroxyflavan (BioDeep_00000007578)

 

Secondary id: BioDeep_00000600155

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,7-diol, 9ci

化学式: C15H14O5 (274.0841)
中文名称: (-)-非瑟酮醇
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 88.39%

分子结构信息

SMILES: C1C(C(OC2=C1C=CC(=C2)O)C3=CC(=C(C=C3)O)O)O
InChI: InChI=1S/C15H14O5/c16-10-3-1-8-5-13(19)15(20-14(8)7-10)9-2-4-11(17)12(18)6-9/h1-4,6-7,13,15-19H,5H2

描述信息

Quebrachocatechin, of undetd. stereochem., isolated from Quebracho in 1934.
Quebrachocatechol is isolated from quebrach

同义名列表

8 个代谢物同义名

2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,7-diol, 9ci; 2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,7-diol; 3,4,7-Trihydroxy-3-flavanol; 3,3,4,7-Tetrahydroxyflavan; 3,7,3,4-tetrahydroxyflavan; (-)-EPICEDROL; Fisetinidol; Fisetinidol



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

34 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 PRKAA2, SREBF1, TNFSF11, TYR
Peripheral membrane protein 1 GBA1
Endoplasmic reticulum membrane 1 SREBF1
Nucleus 4 MPO, PPARA, PRKAA2, SREBF1
cytosol 4 IL1B, LIPE, PRKAA2, SREBF1
dendrite 1 PRKAA2
trans-Golgi network 1 GBA1
nucleoplasm 4 MPO, PPARA, PRKAA2, SREBF1
Cell membrane 3 LIPE, TNF, TNFSF11
Multi-pass membrane protein 2 SREBF1, UCP3
Golgi apparatus membrane 1 SREBF1
cell surface 2 ADIPOQ, TNF
Golgi apparatus 2 GBA1, PRKAA2
Golgi membrane 2 INS, SREBF1
lysosomal membrane 2 GAA, GBA1
mitochondrial inner membrane 1 UCP3
neuronal cell body 2 PRKAA2, TNF
Cytoplasm, cytosol 2 IL1B, LIPE
Lysosome 5 GAA, GBA1, IL1B, MPO, TYR
plasma membrane 4 GAA, TNF, TNFRSF11B, TNFSF11
Membrane 4 GAA, LIPE, PRKAA2, TNFSF11
axon 1 PRKAA2
caveola 1 LIPE
extracellular exosome 4 AMY2A, GAA, GBA1, MPO
Lysosome membrane 2 GAA, GBA1
Lumenal side 1 GBA1
endoplasmic reticulum 3 ADIPOQ, GBA1, SREBF1
extracellular space 9 ADIPOQ, AMY2A, CXCL8, IL1B, INS, MPO, TNF, TNFRSF11B, TNFSF11
lysosomal lumen 2 GAA, GBA1
perinuclear region of cytoplasm 1 TYR
mitochondrion 1 UCP3
protein-containing complex 1 SREBF1
intracellular membrane-bounded organelle 3 GAA, MPO, TYR
Single-pass type I membrane protein 1 TYR
Secreted 7 ADIPOQ, CXCL8, GAA, IL1B, INS, TNFRSF11B, TNFSF11
extracellular region 10 ADIPOQ, AMY2A, CXCL8, GAA, IL1B, INS, MPO, TNF, TNFRSF11B, TNFSF11
external side of plasma membrane 1 TNF
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 2 TNF, TNFSF11
Mitochondrion inner membrane 1 UCP3
Membrane raft 1 TNF
extracellular matrix 1 TNFRSF11B
collagen trimer 1 ADIPOQ
collagen-containing extracellular matrix 1 ADIPOQ
secretory granule 2 IL1B, MPO
nuclear speck 1 PRKAA2
receptor complex 1 TNFRSF11B
chromatin 2 PPARA, SREBF1
phagocytic cup 1 TNF
nuclear envelope 1 SREBF1
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Cytoplasmic vesicle membrane 1 SREBF1
tertiary granule membrane 1 GAA
Melanosome 1 TYR
cytoplasmic stress granule 1 PRKAA2
azurophil granule 1 MPO
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Secreted, extracellular exosome 1 IL1B
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
ER to Golgi transport vesicle membrane 1 SREBF1
[Isoform 2]: Cytoplasm 1 TNFSF11
[Tumor necrosis factor ligand superfamily member 11, soluble form]: Secreted 1 TNFSF11
phagocytic vesicle lumen 1 MPO
ficolin-1-rich granule membrane 1 GAA
nucleotide-activated protein kinase complex 1 PRKAA2
Cytoplasmic vesicle, COPII-coated vesicle membrane 1 SREBF1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
autolysosome lumen 1 GAA
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane 1 SREBF1
[Processed sterol regulatory element-binding protein 1]: Nucleus 1 SREBF1
[Isoform SREBP-1aDelta]: Nucleus 1 SREBF1
[Isoform SREBP-1cDelta]: Nucleus 1 SREBF1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Pieter B Venter, Nadine D Senekal, Gabré Kemp, Maryam Amra-Jordaan, Pir Khan, Susan L Bonnet, Jan H van der Westhuizen. Analysis of commercial proanthocyanidins. Part 3: the chemical composition of wattle (Acacia mearnsii) bark extract. Phytochemistry. 2012 Nov; 83(?):153-67. doi: 10.1016/j.phytochem.2012.07.012. [PMID: 22917955]
  • Xing-Cui Li, Chao Liu, Li-Xin Yang, Ruo-Yun Chen. Phenolic compounds from the aqueous extract of Acacia catechu. Journal of Asian natural products research. 2011 Sep; 13(9):826-30. doi: 10.1080/10286020.2011.597384. [PMID: 21830887]
  • Nobutomo Ikarashi, Takahiro Toda, Takehiro Okaniwa, Kiyomi Ito, Wataru Ochiai, Kiyoshi Sugiyama. Anti-Obesity and Anti-Diabetic Effects of Acacia Polyphenol in Obese Diabetic KKAy Mice Fed High-Fat Diet. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):952031. doi: 10.1093/ecam/nep241. [PMID: 21799697]
  • Nobutomo Ikarashi, Rumi Takeda, Kiyomi Ito, Wataru Ochiai, Kiyoshi Sugiyama. The inhibition of lipase and glucosidase activities by acacia polyphenol. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):272075. doi: 10.1093/ecam/neq043. [PMID: 21660093]
  • Elin Mathisen, Drissa Diallo, Øyvind M Andersen, Karl Egil Malterud. Antioxidants from the bark of Burkea africana, an African medicinal plant. Phytotherapy research : PTR. 2002 Mar; 16(2):148-53. doi: 10.1002/ptr.936. [PMID: 11933117]