Desflurane (BioDeep_00000006522)

human metabolite blood metabolite Volatile Flavor Compounds

代谢物信息卡片

(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether

化学式: C3H2F6O (168.0009834)
中文名称: 脱氟醚1-653
谱图信息: 最多检出来源 Homo sapiens(blood) 89.47%

分子结构信息

SMILES: C(C(F)(F)F)(OC(F)F)F
InChI: InChI=1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H

描述信息

Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into cellular membranes and could expand the volume of the cell membrane and subsequently distort channels necessary for sodium ion flux and the development of action potentials necessary for synaptic transmission. Desflurane preconditions human myocardium against ischemia through activation of mitochondrial K(ATP) channels, adenosine A1 receptor, and alpha and beta adrenoceptors.
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics
N - Nervous system > N01 - Anesthetics > N01A - Anesthetics, general > N01AB - Halogenated hydrocarbons
C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent

同义名列表

12 个代谢物同义名

(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether; 1,1,1,2-Tetrafluoro-2-(difluoromethoxy)ethane; Difluoromethyl 1,2,2,2-tetrafluoroethyl ether; 1,2,2,2-Tetrafluoroethyl difluoromethyl ether; 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane; Baxter anaesthesia brand OF desflurane; Ohmeda brand OF desflurane; Zeneca brand OF desflurane; Baxter brand OF desflurane; DESFLURANE; Suprane; Desflurane

数据库引用编号

16 个数据库交叉引用编号

ChEBI: CHEBI:4445
KEGG: C07519
KEGGdrug: D00546
PubChem: 42113
HMDB: HMDB0015320
Metlin: METLIN66668
DrugBank: DB01189
ChEMBL: CHEMBL1200733
Wikipedia: Desflurane
MeSH: Desflurane
chemspider: 38403
CAS: 57041-67-5
PMhub: MS000019571
PubChem: 9722
NIKKAJI: J444.212A
KNApSAcK: 4445

分类词条

Organofluorides

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

9606 - Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Amitabh Dutta, Nitin Sethi, Goverdhan D Puri, Jayashree Sood, Prabhat Kumar Choudhary, Anil Kumar Jain, Bhuwan Chand Panday, Manish Gupta. Automated Closed-Loop Propofol Anesthesia Versus Desflurane Inhalation Anesthesia in Obese Patients Undergoing Bariatric Surgery: A Comparative Randomized Analysis of Recovery Profile. Asian journal of anesthesiology. 2023 Jun; ?(?):. doi: 10.6859/aja.202306/pp.0001. [PMID: 37386923]
Pedro Alves Machado-Junior, Ana Beatriz Farias de Souza, Thalles de Freitas Castro, Luiza Oliveira Perucci, André Talvani, Silvia Dantas Cangussú, Frank Silva Bezerra. The deleterious impact of exposure to different inhaled anesthetics is time dependent. Life sciences. 2022 Nov; 309(?):121004. doi: 10.1016/j.lfs.2022.121004. [PMID: 36170891]
Thomas A Neff, Julia Braun, Dhanu Rana, Milo Puhan, Miodrag Filipovic, Manfred Seeberger, Frank Stüber, Simona B Neff, Beatrice Beck-Schimmer, Martin Schläpfer. Interleukin-6 Is an Early Plasma Marker of Severe Postoperative Complications in Thoracic Surgery: Exploratory Results From a Substudy of a Randomized Controlled Multicenter Trial. Anesthesia and analgesia. 2022 01; 134(1):123-132. doi: 10.1213/ane.0000000000005639. [PMID: 34132704]
Berna Ayanoğlu Taş, Ceren Şanlı Karip, Süheyla Abitağaoğlu, Mehmet Celal Öztürk, Dilek Erdoğan Arı. Comparison of minimal-flow sevoflurane versus desflurane anesthesia: randomized clinical trial. Brazilian journal of anesthesiology (Elsevier). 2022 Jan; 72(1):77-82. doi: 10.1016/j.bjane.2021.05.012. [PMID: 34119569]
Aycan Ozdemirkan, Aysegul Kucuk, Isin Gunes, Mustafa Arslan, Aydin Tuncay, Volkan Sivgin, Saban C Sezen, Hakan Boyunaga. The effect of cerium oxide on lung injury following lower extremity ischemia-reperfusion injury in rats under desflurane anesthesia. Saudi medical journal. 2021 Nov; 42(11):1247-1251. doi: 10.15537/smj.2021.42.11.20210104. [PMID: 34732559]
Mustafa Tosun, Hasan Olmez, Edhem Unver, Yusuf Kemal Arslan, Ferda Keskin Cimen, Adalet Ozcicek, Mehmet Aktas, Halis Suleyman. Oxidative and pro-inflammatory lung injury induced by desflurane inhalation in rats and the protective effect of rutin. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 2021 Sep; 30(9):941-948. doi: 10.17219/acem/136194. [PMID: 34418333]
Mukilan Balasubramanian, Aswini Kuberan, Amit Rawat, Sivashanmugam Dhandapani, Nidhi Panda, Ajay Kumar, Asish K Sahoo, Munish Kumar, Tanavi Sharma, Paul S Garcia, Hemant Bhagat. Effect of General Anesthetics on Caspase-3 Levels in Patients With Aneurysmal Subarachnoid Hemorrhage: A Preliminary Study. Journal of neurosurgical anesthesiology. 2021 Apr; 33(2):172-176. doi: 10.1097/ana.0000000000000648. [PMID: 31599811]
Mengxia Zhong, Lei Che, Meiqing Du, Ke Liu, Dalong Wang. Desflurane protects against liver ischemia/reperfusion injury via regulating miR-135b-5p. Journal of the Chinese Medical Association : JCMA. 2021 Jan; 84(1):38-45. doi: 10.1097/jcma.0000000000000427. [PMID: 32898087]
Chung-Sik Oh, Ji Min Choi, Eun Hi Park, Liyun Piao, Hyun-Jun Park, Ka-Young Rhee, Seong-Hyop Kim. Impact of Anesthetic Agents on Endothelial Glycocalyx Injury during Total Knee Arthroplasty: Desflurane- vs. Propofol-Based Anesthesia-A Prospective Randomized Controlled Trial. BioMed research international. 2021; 2021(?):8880267. doi: 10.1155/2021/8880267. [PMID: 33564684]
Jaesik Park, Minhee Kim, Yong Hyun Park, Jung-Woo Shim, Hyung Mook Lee, Yong-Suk Kim, Young Eun Moon, Sang Hyun Hong, Min Suk Chae. Comparison of the effects of intravenous propofol and inhalational desflurane on the quality of early recovery after hand-assisted laparoscopic donor nephrectomy: a prospective, randomised controlled trial. BMJ open. 2020 12; 10(12):e039881. doi: 10.1136/bmjopen-2020-039881. [PMID: 33323432]
Arpa Chutipongtanate, Sasichol Prukviwat, Nutkridta Pongsakul, Supanart Srisala, Nakarin Kamanee, Nuttapon Arpornsujaritkun, Goragoch Gesprasert, Nopporn Apiwattanakul, Suradej Hongeng, Wichai Ittichaikulthol, Vasant Sumethkul, Somchai Chutipongtanate. Effects of Desflurane and Sevoflurane anesthesia on regulatory T cells in patients undergoing living donor kidney transplantation: a randomized intervention trial. BMC anesthesiology. 2020 08; 20(1):215. doi: 10.1186/s12871-020-01130-7. [PMID: 32854613]
Arnulfo Calixto-Flores, Monserrat Román-Sánchez, Edgar Jiménez-Sánchez, José Cruz-Santiago, Guillermo Meza-Jiménez, Germán Bernáldez-Gómez. Evaluation of Renal Function at 24, 48, and 72 Hours and 3 Months After Transplant: Comparison of 3 Anesthetic Techniques. Transplantation proceedings. 2020 May; 52(4):1094-1101. doi: 10.1016/j.transproceed.2020.02.011. [PMID: 32178928]
Yan Zheng, Hui Lu, Huiqiong Huang. Desflurane Preconditioning Protects Against Renal Ischemia-Reperfusion Injury and Inhibits Inflammation and Oxidative Stress in Rats Through Regulating the Nrf2-Keap1-ARE Signaling Pathway. Drug design, development and therapy. 2020; 14(?):1351-1362. doi: 10.2147/dddt.s223742. [PMID: 32308368]
Zhi-Fu Wu, Wei-Lin Lin, Meei-Shyuan Lee, Nan-Kai Hung, Yuan-Shiou Huang, Teng-Wei Chen, Chueng-He Lu. Propofol vs desflurane on the cytokine, matrix metalloproteinase-9, and heme oxygenase-1 response during living donor liver transplantation: A pilot study. Medicine. 2019 Nov; 98(48):e18244. doi: 10.1097/md.0000000000018244. [PMID: 31770287]
Nayara M Arruda, Leandro G Braz, Flávia R Nogueira, Kátina M Souza, Aline G Aun, Drielle B S Figueiredo, Juliana R Lara, Mariane Aparecida P Silva, Marjorie A Golim, Lídia R de Carvalho, José Reinaldo C Braz, Mariana G Braz. Inflammation and DNA damage induction in surgical patients maintained with desflurane anesthesia. Mutation research. Genetic toxicology and environmental mutagenesis. 2019 Oct; 846(?):403073. doi: 10.1016/j.mrgentox.2019.07.003. [PMID: 31585635]
Seokyung Shin, Dong J Joo, Myoung S Kim, Myung I Bae, Eunjin Heo, Jong-Seok Lee, Dong W Kim, Young C Yoo. Propofol intravenous anaesthesia with desflurane compared with desflurane alone on postoperative liver function after living-donor liver transplantation: A randomised controlled trial. European journal of anaesthesiology. 2019 Sep; 36(9):656-666. doi: 10.1097/eja.0000000000001018. [PMID: 31083000]
Zafer Cukurova, Halil Cetingok, Sukru Ozturk, Asuman Gedikbasi, Oya Hergunsel, Derya Ozturk, Burak Don, Kivanc Cefle, Sukru Palanduz, Devrimsel Harika Ertem. DNA damage effects of inhalation anesthetics in human bronchoalveolar cells. Medicine. 2019 Aug; 98(32):e16518. doi: 10.1097/md.0000000000016518. [PMID: 31393354]
Bridget Bishop, Nicholas Hannah, Adam Doyle, Francesco Amico, Brad Hockey, David Moore, Siddharth Sood, Alexandra Gorelik, Danny Liew, Dolores Njoku, Amanda Nicoll. A prospective study of the incidence of drug-induced liver injury by the modern volatile anaesthetics sevoflurane and desflurane. Alimentary pharmacology & therapeutics. 2019 04; 49(7):940-951. doi: 10.1111/apt.15168. [PMID: 30761577]
Meltem Savran Karadeniz, Hayriye Senturk Ciftci, Tzevat Tefik, Tayfun Oktar, Ismet Nane, Aydin Turkmen, Fatma Oguz, Kamil Mehmet Tugrul. Effects of Different Volatile Anesthetics on Cytokine and Chemokine Production After Ischemia-Reperfusion Injury in Patients Undergoing Living-Donor Kidney Transplant. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 2019 01; 17(Suppl 1):68-74. doi: 10.6002/ect.mesot2018.o10. [PMID: 30777526]
David Miller, Sharon R Lewis, Michael W Pritchard, Oliver J Schofield-Robinson, Cliff L Shelton, Phil Alderson, Andrew F Smith. Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. The Cochrane database of systematic reviews. 2018 08; 8(?):CD012317. doi: 10.1002/14651858.cd012317.pub2. [PMID: 30129968]
R S Mangus, S B Kinsella, D T Farar, J A Fridell, L T Woolf, C A Kubal. Impact of Volatile Anesthetic Agents on Early Clinical Outcomes in Liver Transplantation. Transplantation proceedings. 2018 Jun; 50(5):1372-1377. doi: 10.1016/j.transproceed.2018.03.001. [PMID: 29880359]
Flávia R Nogueira, Leandro G Braz, Kátina M Souza, Aline G Aun, Nayara M Arruda, Lídia R Carvalho, Chung-Yen O Chen, José Reinaldo C Braz, Mariana G Braz. Comparison of DNA Damage and Oxidative Stress in Patients Anesthetized With Desflurane Associated or Not With Nitrous Oxide: A Prospective Randomized Clinical Trial. Anesthesia and analgesia. 2018 04; 126(4):1198-1205. doi: 10.1213/ane.0000000000002729. [PMID: 29293177]
Xue Lin, Ying-Nan Ju, Wei Gao, Dong-Mei Li, Chang-Chun Guo. Desflurane Attenuates Ventilator-Induced Lung Injury in Rats with Acute Respiratory Distress Syndrome. BioMed research international. 2018; 2018(?):7507314. doi: 10.1155/2018/7507314. [PMID: 29670906]
Preet Mohinder Singh, Anuradha Borle, Jason McGavin, Anjan Trikha, Ashish Sinha. Comparison of the Recovery Profile between Desflurane and Sevoflurane in Patients Undergoing Bariatric Surgery-a Meta-Analysis of Randomized Controlled Trials. Obesity surgery. 2017 11; 27(11):3031-3039. doi: 10.1007/s11695-017-2929-6. [PMID: 28916989]
M S Karadeniz, H S Ciftci, T Tefik, O Mammadov, H Yazıcı, I Nane, A Turkmen, F Oguz, K M Tugrul. Comparison of Two Different Inhalation Anesthetics on Grafted Kidney Function in Patients Undergoing Renal Transplantation Surgery: Desflurane or Sevoflurane?. Transplantation proceedings. 2017 Apr; 49(3):448-453. doi: 10.1016/j.transproceed.2017.01.014. [PMID: 28340810]
Derek R Laver, John Attia, Christopher Oldmeadow, Anthony W Quail. Cardiac Calcium Release Channel (Ryanodine Receptor 2) Regulation by Halogenated Anesthetics. Anesthesiology. 2017 Mar; 126(3):495-506. doi: 10.1097/aln.0000000000001519. [PMID: 28079567]
D X Kang, Y Q Rao, B Ji, J Li. [Effects of sevoflurane and desflurane on pharmacodynamics of rocuronium in children]. Zhonghua yi xue za zhi. 2017 Feb; 97(6):429-433. doi: 10.3760/cma.j.issn.0376-2491.2017.06.006. [PMID: 28219129]
Safinaz Karabayirli, Onder Surgit, Hulya Kasikara, Cemile Koca Bicer, Merve Ergin, Ruveyda Irem Demircioglu, Bunyamin Muslu. The effects of adding ischemic preconditioning during desflurane inhalation anesthesia or propofol total intravenous anesthesia on pneumoperitoneum-induced oxidative stress. Acta chirurgica Belgica. 2017 Feb; 117(1):36-44. doi: 10.1080/00015458.2016.1242215. [PMID: 27771984]
Sumidtra Prathep, Sasithorn Mahattanaporn, Wirat Wasinwong. Target Controlled Infusion versus Sevoflurane/Desflurane Anesthesia for Laparoscopic Cholecystectomy: Comparison Postoperative Nausea/Vomiting and Extubation Time. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2015 Dec; 98(12):1187-92. doi: NULL. [PMID: 27004303]
Alexandre Hideaki Oshiro, Denise Aya Otsuki, Marcelo Waldir M Hamaji, Kaleizu T Rosa, Keila Kazue Ida, Denise T Fantoni, José Otavio Costa Auler. Pulse pressure variation and stroke volume variation under different inhaled concentrations of isoflurane, sevoflurane and desflurane in pigs undergoing hemorrhage. Clinics (Sao Paulo, Brazil). 2015 Dec; 70(12):804-9. doi: 10.6061/clinics/2015(12)07. [PMID: 26735220]
Jae Hee Woo, Hee Jung Baik, Chi Hyo Kim, Rack Kyung Chung, Dong Yeon Kim, Guie Yong Lee, Eun Hee Chun. Effect of Propofol and Desflurane on Immune Cell Populations in Breast Cancer Patients: A Randomized Trial. Journal of Korean medical science. 2015 Oct; 30(10):1503-8. doi: 10.3346/jkms.2015.30.10.1503. [PMID: 26425050]
Poonam Malhotra Kapoor, Sameer Taneja, Usha Kiran, P Rajashekhar. Comparison of the effects of inhalational anesthesia with desflurane and total intravenous anesthesia on cardiac biomarkers after aortic valve replacement. Annals of cardiac anaesthesia. 2015 Oct; 18(4):502-9. doi: 10.4103/0971-9784.166455. [PMID: 26440236]
M Abou Hussein, F Mahmoud, R Beltagy, A Hasanin, K Yassen, A Attar. DESFLURANE COMPARED TO SEVOFLURANE FOR CIRRHOTIC PATIENTS UNDERGOING MAJOR LIVER RESECTION. A RANDOMIZED CONTROL STUDY. Middle East journal of anaesthesiology. 2015 Jun; 23(2):213-23. doi: . [PMID: 26442399]
Dilek Kalaycı, Bayazit Dikmen, Murat Kaçmaz, Vildan Taşpınar, Dilşen Ornek, Ozlem Turan. Plasma levels of interleukin-10 and nitric oxide in response to two different desflurane anesthesia flow rates. Brazilian journal of anesthesiology (Elsevier). 2014 Jul; 64(4):292-8. doi: 10.1016/j.bjane.2013.06.008. [PMID: 24998117]
Elif Doğan Baki, Mustafa Aldemir, Serdar Kokulu, Halit Buğra Koca, Yüksel Ela, Remziye Gül Sıvacı, Nilgün Kavrut Öztürk, Mustafa Emmiler, Fahri Adalı, Hanife Uzel. Comparison of the effects of desflurane and propofol anesthesia on the inflammatory response and s100β protein during coronary artery bypass grafting. Inflammation. 2013 Dec; 36(6):1327-33. doi: 10.1007/s10753-013-9671-6. [PMID: 23775574]
You Yu, Yan Zhang. Desflurane accelerates neuronal cytotoxicity of Aβ by downregulating miR-214. Neuroscience letters. 2013 Oct; 554(?):28-33. doi: 10.1016/j.neulet.2013.08.063. [PMID: 24021802]
Min-Soo Kim, Jeong-Rim Lee, Myoung-Soo Kim, Sung-Yeon Ham, Seung-Ho Choi. Kidney function in living donors undergoing nephrectomy by sevoflurane or desflurane anesthesia. Yonsei medical journal. 2013 Sep; 54(5):1266-72. doi: 10.3349/ymj.2013.54.5.1266. [PMID: 23918580]
Saban Yalcin, Harun Aydoğan, Hasan Husnu Yuce, Ahmet Kucuk, Mahmut Alp Karahan, Mehmet Vural, Aysun Camuzcuoğlu, Nurten Aksoy. Effects of sevoflurane and desflurane on oxidative stress during general anesthesia for elective cesarean section. Wiener klinische Wochenschrift. 2013 Aug; 125(15-16):467-73. doi: 10.1007/s00508-013-0397-0. [PMID: 23860695]
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Pooja Singh, Sandeep Chauhan, Gaurav Jain, Sachin Talwar, Neeti Makhija, Usha Kiran. Comparison of cardioprotective effects of volatile anesthetics in children undergoing ventricular septal defect closure. World journal for pediatric & congenital heart surgery. 2013 Jan; 4(1):24-9. doi: 10.1177/2150135112457580. [PMID: 23799751]
E Marana, A Russo, S Colicci, L Polidori, F Bevilacqua, D Viviani, E Di Stasio. Desflurane versus sevoflurane: a comparison on stress response. Minerva anestesiologica. 2013 Jan; 79(1):7-14. doi: . [PMID: 23090102]
Bruno Laviolle, Cédric Basquin, David Aguillon, Philippe Compagnon, Isabelle Morel, Valérie Turmel, Philippe Seguin, Karim Boudjema, Eric Bellissant, Yannick Mallédant. Effect of an anesthesia with propofol compared with desflurane on free radical production and liver function after partial hepatectomy. Fundamental & clinical pharmacology. 2012 Dec; 26(6):735-42. doi: 10.1111/j.1472-8206.2011.00958.x. [PMID: 21692846]
Tumer Aldemir, Sema Turan, Ismail Gomceli, Ihsan Ayik, Ozlem Erdem, Seyhan Yagar, Nurhan Kul, Ozcan Erdemli. A comparison of the effects of desflurane and isoflurane on rat pulmonary parenchyme histopathology and malondialdehyde levels. JPMA. The Journal of the Pakistan Medical Association. 2012 Nov; 62(11):1174-8. doi: ". [PMID: 23866405]
H I Toprak, T Şahin, S Aslan, K Karahan, M Şanli, M Ö Ersoy. Effects of desflurane and isoflurane on hepatic and renal functions and coagulation profile during donor hepatectomy. Transplantation proceedings. 2012 Jul; 44(6):1635-9. doi: 10.1016/j.transproceed.2012.05.047. [PMID: 22841233]
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Jin Ha Park, Jae Hoon Lee, Dong Jin Joo, Ki Jun Song, Yu Seun Kim, Bon-Nyeo Koo. Effect of sevoflurane on grafted kidney function in renal transplantation. Korean journal of anesthesiology. 2012 Jun; 62(6):529-35. doi: 10.4097/kjae.2012.62.6.529. [PMID: 22778888]
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Sheryl H Glassman, Michael S Green, Melissa Brodsky. Asystole following Reintubation during Suspension Laryngoscopy. Case reports in anesthesiology. 2012; 2012(?):916306. doi: 10.1155/2012/916306. [PMID: 22606412]
Maria I Lioudyno, Matteo Broccio, Yuri Sokolov, Suhail Rasool, Jessica Wu, Michael T Alkire, Virginia Liu, J Ashot Kozak, Philip R Dennison, Charles G Glabe, Mathias Lösche, James E Hall. Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance. PloS one. 2012; 7(4):e35090. doi: 10.1371/journal.pone.0035090. [PMID: 22563377]
Thomas Schilling, Alf Kozian, Mert Senturk, Christof Huth, Annegret Reinhold, Göran Hedenstierna, Thomas Hachenberg. Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients. Anesthesiology. 2011 Jul; 115(1):65-74. doi: 10.1097/aln.0b013e318214b9de. [PMID: 21399490]
Berit G Ceylan, Mustafa Nazıroğlu, A Cihangir Uğuz, Cihan Barak, Bülent Erdem, Lütfi Yavuz. Effects of vitamin C and E combination on element and oxidative stress levels in the blood of operative patients under desflurane anesthesia. Biological trace element research. 2011 Jun; 141(1-3):16-25. doi: 10.1007/s12011-010-8712-3. [PMID: 20464539]
Hülya Türkan, Ahmet Aydin, Ahmet Sayal, Ayşe Eken, Cemal Akay, Bensu Karahalil. Oxidative and antioxidative effects of desflurane and sevoflurane on rat tissue in vivo. Arhiv za higijenu rada i toksikologiju. 2011 Jun; 62(2):113-9. doi: 10.2478/10004-1254-62-2011-2096. [PMID: 21705298]
Leda Kovatsi, Dimitrios Giannakis, Vasileios Arzoglou, Victoria Samanidou. Development and validation of a direct headspace GC-FID method for the determination of sevoflurane, desflurane and other volatile compounds of forensic interest in biological fluids: application on clinical and post-mortem samples. Journal of separation science. 2011 May; 34(9):1004-10. doi: 10.1002/jssc.201000921. [PMID: 21404443]
Tobias Eckle, Michael Koeppen, Holger Eltzschig. Use of a hanging weight system for coronary artery occlusion in mice. Journal of visualized experiments : JoVE. 2011 Apr; ?(50):. doi: 10.3791/2526. [PMID: 21540816]
Jae Hyun Ahn, Choon Hak Lim, Hye In Chung, Seong Uk Choi, Seung Zoo Youn, Hae Ja Lim. Postoperative renal function in patients is unaltered after robotic-assisted radical prostatectomy. Korean journal of anesthesiology. 2011 Mar; 60(3):192-7. doi: 10.4097/kjae.2011.60.3.192. [PMID: 21490821]
H Türkan, A Aydin, A Sayal, B Karahalil. The effect of sevoflurane and desflurane on markers of oxidative status in erythrocyte. Toxicology and industrial health. 2011 Mar; 27(2):181-6. doi: 10.1177/0748233710384911. [PMID: 20935031]
Leopold H J Eberhart, Jürgen Graf, Astrid M Morin, Thomas Stief, Matthias Kalder, Ralph Lattermann, Thomas Schricker. Randomised controlled trial of the effect of oral premedication with dexamethasone on hyperglycaemic response to abdominal hysterectomy. European journal of anaesthesiology. 2011 Mar; 28(3):195-201. doi: 10.1097/eja.0b013e32834296b9. [PMID: 21192268]
Dong Hun Chung, Nan Sook Kim, Mi Kyoung Lee, Hee-Kyung Jo. The effect and optimal dose of sufentanil in reducing injection pain of microemulsion propofol. Korean journal of anesthesiology. 2011 Feb; 60(2):83-9. doi: 10.4097/kjae.2011.60.2.83. [PMID: 21390162]
Woosik Eom, Jung Min Lee, Jeongmi Park, Kyungho Choi, Sung-Jun Jung, Hee-Soo Kim. The effects of midazolam and sevoflurane on the GABA(A) receptors with alternatively spliced variants of the γ2 subunit. Korean journal of anesthesiology. 2011 Feb; 60(2):109-18. doi: 10.4097/kjae.2011.60.2.109. [PMID: 21390166]
Siva K Nalabotu, Madhukar B Kolli, William E Triest, Jane Y Ma, Nandini D P K Manne, Anjaiah Katta, Hari S Addagarla, Kevin M Rice, Eric R Blough. Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats. International journal of nanomedicine. 2011; 6(?):2327-35. doi: 10.2147/ijn.s25119. [PMID: 22072870]
Khaled Mahmoud, Amany Ammar. Immunomodulatory Effects of Anesthetics during Thoracic Surgery. Anesthesiology research and practice. 2011; 2011(?):317410. doi: 10.1155/2011/317410. [PMID: 22110498]
Soon Eun Park, Dae-Young Kim, Eun-Sun Park. Hyperkalemia in a patient with rhabdomyolysis and compartment syndrome -A case report-. Korean journal of anesthesiology. 2010 Dec; 59 Suppl(?):S37-40. doi: 10.4097/kjae.2010.59.s.s37. [PMID: 21286456]
Carsten Ochmann, Benjamin Tuschy, Ralf Beschmann, Florian Hamm, Kerstin D Röhm, Swen N Piper. Supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting. European journal of anaesthesiology. 2010 Dec; 27(12):1036-43. doi: 10.1097/eja.0b013e32833b04e4. [PMID: 20613542]
M P Sulbaek Andersen, S P Sander, O J Nielsen, D S Wagner, T J Sanford, T J Wallington. Inhalation anaesthetics and climate change. British journal of anaesthesia. 2010 Dec; 105(6):760-6. doi: 10.1093/bja/aeq259. [PMID: 20935004]
F K Pühringer, P Kristen, C Rex. Sugammadex reversal of rocuronium-induced neuromuscular block in Caesarean section patients: a series of seven cases. British journal of anaesthesia. 2010 Nov; 105(5):657-60. doi: 10.1093/bja/aeq227. [PMID: 20736231]
Joy Allee, Joseph D Tobias. Perioperative care of a child with non-ketotic hyperglycinemia. Saudi journal of anaesthesia. 2010 Sep; 4(3):197-201. doi: 10.4103/1658-354x.71578. [PMID: 21189859]
Cynthia A Wong. Advances in labor analgesia. International journal of women's health. 2010 Aug; 1(?):139-54. doi: 10.2147/ijwh.s4553. [PMID: 21072284]
Hendrikus J m Lemmens. Perioperative pharmacology in morbid obesity. Current opinion in anaesthesiology. 2010 Aug; 23(4):485-91. doi: 10.1097/aco.0b013e32833b0a8c. [PMID: 20531173]
M-L Guye, B Mc Gregor, G Weil, F Arnal, V Piriou. [Ischaemic and pharmacologic preconditioning: desflurane reduces renal reperfusion injury in rabbits]. Annales francaises d'anesthesie et de reanimation. 2010 Jul; 29(7-8):518-23. doi: 10.1016/j.annfar.2010.03.027. [PMID: 20621434]
Justin S Ko, Mi S Gwak, Soo J Choi, Mikyung Yang, Myung J Kim, Jin Y Lee, Gaab S Kim, Choon H D Kwon, Jae W Joh. The effects of desflurane and sevoflurane on hepatic and renal functions after right hepatectomy in living donors*. Transplant international : official journal of the European Society for Organ Transplantation. 2010 Jul; 23(7):736-44. doi: 10.1111/j.1432-2277.2009.01050.x. [PMID: 20102552]
Eun Ho Lee, Sun-Key Kim, Young Goo Yeo, Kyu Taek Choi. Effects of anesthesia on fluid volume kinetics after infusion of colloid solution during blood donation. Korean journal of anesthesiology. 2010 Jun; 58(6):514-20. doi: 10.4097/kjae.2010.58.6.514. [PMID: 20589174]
Fusun Eroglu, Lutfi Yavuz, Berit G Ceylan, Funda Yilmaz, Erol Eroglu, Namik Delibas, Mustafa Naziroğlu. New volatile anesthetic, desflurane, reduces vitamin E level in blood of operative patients via oxidative stress. Cell biochemistry and function. 2010 Apr; 28(3):211-6. doi: 10.1002/cbf.1641. [PMID: 20232492]
Georgia Kostopanagiotou, Konstantinos Kalimeris, Kalliopi Christodoulaki, Constantinos Nastos, Nikolaos Papoutsidakis, Cleanthi Dima, Charalampos Chrelias, Ageliki Pandazi, Iordanis Mourouzis, Constantinos Pantos. The differential impact of volatile and intravenous anaesthetics on stress response in the swine. Hormones (Athens, Greece). 2010 Jan; 9(1):67-75. doi: 10.14310/horm.2002.1255. [PMID: 20363724]
Natalie Urwyler, Sven Trelle, Lorenz Theiler, Peter Jüni, Lukas P Staub, Cedric Luyet, Lorenzo Alberio, Kay Stricker, Robert Greif. Does point of care prothrombin time measurement reduce the transfusion of fresh frozen plasma in patients undergoing major surgery? The POC-OP randomized-controlled trial. Trials. 2009 Nov; 10(?):107. doi: 10.1186/1745-6215-10-107. [PMID: 19930626]
Richard K Ellerkmann, Joergen Bruhn, Martin Soehle, Michael Kehrer, Andreas Hoeft, Sascha Kreuer. Maximizing prediction probability PK as an alternative semiparametric approach to estimate the plasma effect-site equilibration rate constant ke0. Anesthesia and analgesia. 2009 Nov; 109(5):1470-8. doi: 10.1213/ane.0b013e3181b61efd. [PMID: 19713250]
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Jasper Stevens, Ernst Suidgeest, Piet Hein van der Graaf, Meindert Danhof, Elizabeth C M de Lange. A new minimal-stress freely-moving rat model for preclinical studies on intranasal administration of CNS drugs. Pharmaceutical research. 2009 Aug; 26(8):1911-7. doi: 10.1007/s11095-009-9907-1. [PMID: 19452129]
Thomas Meyer, Joseph D Tobias. Perioperative blood pressure management with clevidipine during coiling of cerebral artery aneurysms. Saudi journal of anaesthesia. 2009 Jul; 3(2):83-6. doi: 10.4103/1658-354x.57880. [PMID: 20532109]
Seung Ho Choi, Chang Seok Kim, Jong Hoon Kim, Bum Su Kim, Eun Mi Kim, Kyeong Tae Min. A single dose of esmolol blunts the increase in bispectral index to tracheal intubation during sevoflurane but not desflurane anesthesia. Journal of neurosurgical anesthesiology. 2009 Jul; 21(3):214-7. doi: 10.1097/ana.0b013e3181a41e69. [PMID: 19542998]
Berit G Ceylan, Funda Yilmaz, Fusun Eroglu, Lutfi Yavuz, Senol Gulmen, Huseyin Vural. Oxidant and antioxidant activities of different anesthetic techniques. Propofol versus desflurane. Saudi medical journal. 2009 Mar; 30(3):371-6. doi: . [PMID: 19271065]
K E Joubert. Computer simulations of propofol infusions for total intravenous anaesthesia in dogs. Journal of the South African Veterinary Association. 2009 Mar; 80(1):2-9. doi: 10.4102/jsava.v80i1.161. [PMID: 19653512]
P Gritti, B Carrara, M Khotcholava, G Bortolotti, D Giardini, L A Lanterna, A Benigni, V Sonzogni. The use of desflurane or propofol in combination with remifentanil in myasthenic patients undergoing a video-assisted thoracoscopic-extended thymectomy. Acta anaesthesiologica Scandinavica. 2009 Mar; 53(3):380-9. doi: 10.1111/j.1399-6576.2008.01853.x. [PMID: 19243323]
Fang Luo, Nan Ji, Shuzhen Zhang, Jizong Zhao, Tao Wang. Changes of endothelin and calcitonin gene-related peptide concentrations in plasma during propofol anesthesia. Journal of neurosurgical anesthesiology. 2009 Jan; 21(1):47-50. doi: 10.1097/ana.0b013e31818a65b7. [PMID: 19098623]
Endrit Bala, Daniel I Sessler, Dileep R Nair, Robert McLain, Jarrod E Dalton, Ehab Farag. Motor and somatosensory evoked potentials are well maintained in patients given dexmedetomidine during spine surgery. Anesthesiology. 2008 Sep; 109(3):417-25. doi: 10.1097/aln.0b013e318182a467. [PMID: 18719439]
Justin Sang Ko, Mi Sook Gwak, Soo Joo Choi, Gaab Soo Kim, Jie Ae Kim, Mikyung Yang, Sangmin Maria Lee, Hyun Sung Cho, In Sun Chung, Myung Hee Kim. The effects of desflurane and propofol-remifentanil on postoperative hepatic and renal functions after right hepatectomy in liver donors. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2008 Aug; 14(8):1150-8. doi: 10.1002/lt.21490. [PMID: 18668648]
E Dedola, A Albertin, D Poli, L La Colla, A Gandolfi, C Martani, G Torri. Effect of nitrous oxide on desflurane MACBAR at two target-controlled concentrations of remifentanil. Minerva anestesiologica. 2008 May; 74(5):165-72. doi: NULL. [PMID: 18414359]
Nan Chiang, Jan M Schwab, Gabrielle Fredman, Kie Kasuga, Simon Gelman, Charles N Serhan. Anesthetics impact the resolution of inflammation. PloS one. 2008 Apr; 3(4):e1879. doi: 10.1371/journal.pone.0001879. [PMID: 18382663]
Betty Herndon, Mark Yagan, George Reisz, J C Ireland. Metabolic and biochemical responses of the healthy human lung to nonthoracic surgery. Lung. 2008 Jan; 186(1):63-70. doi: 10.1007/s00408-007-9058-2. [PMID: 18066622]
G Baldini, H Bagry, F Carli. Depth of anesthesia with desflurane does not influence the endocrine-metabolic response to pelvic surgery. Acta anaesthesiologica Scandinavica. 2008 Jan; 52(1):99-105. doi: 10.1111/j.1399-6576.2007.01470.x. [PMID: 17976225]
Colin Forbes Royse, David F L Liew, Christine E Wright, Alistair G Royse, James A Angus. Persistent depression of contractility and vasodilation with propofol but not with sevoflurane or desflurane in rabbits. Anesthesiology. 2008 Jan; 108(1):87-93. doi: 10.1097/01.anes.0000296077.32685.26. [PMID: 18156886]
Cecilia M Rosales, Thomas Young, Michael J Laster, Edmond I Eger, Uttam Garg. Sevoflurane concentrations in blood, brain, and lung after sevoflurane-induced death. Journal of forensic sciences. 2007 Nov; 52(6):1408-10. doi: 10.1111/j.1556-4029.2007.00556.x. [PMID: 17944910]
Bahar Oc, Meral Kanbak, Seda B Akinci, Eda Satana, Ulku Aypar. The perioperative renal function in cyanotic versus acyanotic children undergoing desflurane anesthesia for open-heart surgery. Saudi medical journal. 2007 Nov; 28(11):1753-5. doi: NULL. [PMID: 17965808]
Ahmet Koroglu, Muslum Cicek, Huseyin I Toprak, Yunus Karakoc, Funda Noyan, Ozcan M Ersoy. Comparison of the effects of desflurane and sevoflurane on the expression of platelet surface glycoproteins in unstimulated and adenosine diphosphate-induced platelets in vitro. Journal of clinical anesthesia. 2007 Aug; 19(5):328-33. doi: 10.1016/j.jclinane.2007.02.002. [PMID: 17869981]
Massimo Meco, Silvia Cirri, Chiara Gallazzi, Giulia Magnani, Daniele Cosseta. Desflurane preconditioning in coronary artery bypass graft surgery: a double-blinded, randomised and placebo-controlled study. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 2007 Aug; 32(2):319-25. doi: 10.1016/j.ejcts.2007.05.005. [PMID: 17574858]
G Cinnella, G Vendemiale, M Dambrosio, G Serviddio, P L Pugliese, G Aspromonte, E Altomare. Effect of Propofol, Sevoflurane and Desflurane on systemic redox balance. International journal of immunopathology and pharmacology. 2007 Jul; 20(3):585-93. doi: 10.1177/039463200702000316. [PMID: 17880771]
S Kreuer, J Bruhn, W Wilhelm, T Bouillon. [Pharmacokinetic-pharmacodynamic models for inhaled anaesthetics]. Der Anaesthesist. 2007 Jun; 56(6):538-56. doi: 10.1007/s00101-007-1188-7. [PMID: 17530207]
Theodosios Saranteas, Annete Tachmintzis, Nikos Katsikeris, Eustathios Lykoudis, Iordanis Mourouzis, Dimitrios Anteriotis, Chrisanthos Alexopoulos, Antonia Dimakopoulou, Vasilios Dimitriou, Costantinos Pantos, Christina Tesseromatis. Perioperative thyroid hormone kinetics in patients undergoing major oral and maxillofacial operations. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 2007 Mar; 65(3):408-14. doi: 10.1016/j.joms.2005.12.067. [PMID: 17307585]
M D Larson, P D Berry, J May, A Bjorksten, D I Sessler. Autonomic effects of epidural and intravenous fentanyl. British journal of anaesthesia. 2007 Feb; 98(2):263-9. doi: 10.1093/bja/ael335. [PMID: 17210735]