Encainide (BioDeep_00000006391)
Secondary id: BioDeep_00001868244
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
(+-)-4-Methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide
化学式: C22H28N2O2 (352.2151)
中文名称: (±)-4-甲氧基-N-[2-[2-(1-甲基-2-哌啶基)乙基]苯基]苯甲酰胺, 恩卡尼
谱图信息:
最多检出来源 Homo sapiens(blood) 20.73%
分子结构信息
SMILES: CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC
InChI: InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25)
描述信息
All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
C - Cardiovascular system > C01 - Cardiac therapy > C01B - Antiarrhythmics, class i and iii > C01BC - Antiarrhythmics, class ic
D002317 - Cardiovascular Agents > D026941 - Sodium Channel Blockers > D061567 - Voltage-Gated Sodium Channel Blockers
C78274 - Agent Affecting Cardiovascular System > C47793 - Antiarrhythmic Agent
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
D049990 - Membrane Transport Modulators
C93038 - Cation Channel Blocker
同义名列表
18 个代谢物同义名
(+-)-4-Methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide; 4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide; BENZAMIDE, 4-METHOXY-N-[2-[2-(1-METHYL-2-PIPERIDINYL)ETHYL]PHENYL]-; 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide; 4-Methoxy-2-[2-(1-methyl-2-piperidyl)ethyl]benzanilide; Bristol-myers squibb brand OF encainide hydrochloride; Bristol myers squibb brand OF encainide hydrochloride; (+-)-2-[2-(1-Methyl-2-piperidyl)ethyl]-p-anisanilide; Encainide hydrochloride, (+-)-isomer; Encainide hydrochloride; Encainide, (-)-isomer; Encainide, (+)-isomer; Encainidum; Encainide; Encainida; Enkaid; Encainide; Encainide
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:4788
- KEGG: C06978
- KEGGdrug: D07894
- PubChem: 48041
- HMDB: HMDB0015359
- Metlin: METLIN66566
- DrugBank: DB01228
- ChEMBL: CHEMBL315838
- Wikipedia: Encainide
- MeSH: Encainide
- chemspider: 43697
- CAS: 37612-13-8
- CAS: 66778-36-7
- PMhub: MS000019425
- PubChem: 9192
- NIKKAJI: J244.570K
- KNApSAcK: 4788
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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1982 Sep; 4(5):812-9. doi:
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The Journal of pharmacology and experimental therapeutics.
1982 Jun; 221(3):552-7. doi:
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Clinical pharmacology and therapeutics.
1982 Apr; 31(4):427-32. doi:
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The American journal of cardiology.
1982 Apr; 49(5):1270-8. doi:
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The American journal of cardiology.
1981 Nov; 48(5):871-6. doi:
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Circulation.
1981 Aug; 64(2):290-6. doi:
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1981 May; 3(3):532-40. doi:
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1980 Sep; 2(5):517-26. doi:
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The New England journal of medicine.
1980 Apr; 302(16):877-82. doi:
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