(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate (BioDeep_00000005230)

 

Secondary id: BioDeep_00001869619

human metabolite


代谢物信息卡片


[(2R,3S)-2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acid

化学式: C11H14NO6P (287.05587140000006)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(natural_products) 0.29%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=CN2)C(C(COP(=O)(O)O)O)O
InChI: InChI=1S/C11H14NO6P/c13-10(6-18-19(15,16)17)11(14)8-5-12-9-4-2-1-3-7(8)9/h1-5,10-14H,6H2,(H2,15,16,17)

描述信息

Indole-3-glycerol phosphate, also known as c1-(3-indolyl)-glycerol 3-phosphate, is a member of the class of compounds known as 3-alkylindoles. 3-alkylindoles are compounds containing an indole moiety that carries an alkyl chain at the 3-position. Indole-3-glycerol phosphate is slightly soluble (in water) and a moderately acidic compound (based on its pKa). Indole-3-glycerol phosphate can be found in a number of food items such as german camomile, lambsquarters, other soy product, and hazelnut, which makes indole-3-glycerol phosphate a potential biomarker for the consumption of these food products. Indole-3-glycerol phosphate may be a unique E.coli metabolite.
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents

同义名列表

14 个代谢物同义名

[(2R,3S)-2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acid; (1S,2R)-1-C-(indol-3-yl)Glycerol 3-phosphoric acid; (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate; 1-C-(indol-3-yl)Glycerol 3-phosphoric acid; C1-(3-Indolyl)-glycerol 3-phosphoric acid; (3-Indolyl)-glycerol phosphoric acid; 1-C-(Indol-3-yl)glycerol 3-phosphate; C1-(3-Indolyl)-glycerol 3-phosphate; Indole-3-glycerol phosphoric acid; Indoleglycerol phosphoric acid; (3-Indolyl)-glycerol phosphate; Indole-3-glycerol phosphate; Indole-3-glycerophosphate; Indoleglycerol phosphate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

334 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

WikiPathways(1)

Plant Reactome(330)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lenny Ferrer, Melanie Mindt, Maria Suarez-Diez, Tatjana Jilg, Maja Zagorščak, Jin-Ho Lee, Kristina Gruden, Volker F Wendisch, Katarina Cankar. Fermentative Indole Production via Bacterial Tryptophan Synthase Alpha Subunit and Plant Indole-3-Glycerol Phosphate Lyase Enzymes. Journal of agricultural and food chemistry. 2022 May; 70(18):5634-5645. doi: 10.1021/acs.jafc.2c01042. [PMID: 35500281]
  • Anna Wlazło, Magdalena Święcicka, Marek D Koter, Tomasz Krępski, Leszek Bolibok, Anna Stochmal, Mariusz Kowalczyk, Monika Rakoczy-Trojanowska. Genes ScBx1 and ScIgl-Competitors or Cooperators?. Genes. 2020 02; 11(2):. doi: 10.3390/genes11020223. [PMID: 32093268]
  • Katrin Schullehner, Regina Dick, Florian Vitzthum, Wilfried Schwab, Wolfgang Brandt, Monika Frey, Alfons Gierl. Benzoxazinoid biosynthesis in dicot plants. Phytochemistry. 2008 Nov; 69(15):2668-77. doi: 10.1016/j.phytochem.2008.08.023. [PMID: 18929374]
  • M Frey, C Stettner, P W Pare, E A Schmelz, J H Tumlinson, A Gierl. An herbivore elicitor activates the gene for indole emission in maize. Proceedings of the National Academy of Sciences of the United States of America. 2000 Dec; 97(26):14801-6. doi: 10.1073/pnas.260499897. [PMID: 11106389]
  • J Ouyang, X Shao, J Li. Indole-3-glycerol phosphate, a branchpoint of indole-3-acetic acid biosynthesis from the tryptophan biosynthetic pathway in Arabidopsis thaliana. The Plant journal : for cell and molecular biology. 2000 Nov; 24(3):327-33. doi: 10.1046/j.1365-313x.2000.00883.x. [PMID: 11069706]
  • X J Yang, E W Miles. Threonine 183 and adjacent flexible loop residues in the tryptophan synthase alpha subunit have critical roles in modulating the enzymatic activities of the beta subunit in the alpha 2 beta 2 complex. The Journal of biological chemistry. 1992 Apr; 267(11):7520-8. doi: NULL. [PMID: 1559990]
  • . . . . doi: . [PMID: 11556781]