Vitamin K (BioDeep_00000004129)

 

Secondary id: BioDeep_00000017491

PANOMIX_OTCML-2023 natural product BioNovoGene_Lab2019


代谢物信息卡片


2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-dione

化学式: C31H46O2 (450.34976159999997)
中文名称: 维生素K, 维他命K, 维生素K1, 维生素 K1
谱图信息: 最多检出来源 Viridiplantae(plant) 50%

分子结构信息

SMILES: CC(=CCC1=C(C)C(=O)c2ccccc2C1=O)CCCC(C)CCCC(C)CCCC(C)C
InChI: InChI=1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+

描述信息

D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics
D050299 - Fibrin Modulating Agents > D000933 - Antifibrinolytic Agents
D018977 - Micronutrients > D014815 - Vitamins
Widely distributed in green leaves and vegetables, especies cabbage and spinach. Infant formula fortifier. Phytomenadione is found in many foods, some of which are swiss chard, fruit salad, milk (cow), and common buckwheat.
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

同义名列表

10 个代谢物同义名

Vitamin K; Phytomenadione; 2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-dione; 2-methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)naphthalene-1,4-dione; 2-Methyl-3-phytyl-1,4-naphthoquinone; Phylloquinone; Phytonadione; Vitamin K1; Phylloquinone; Vitamin K



数据库引用编号

32 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

10 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(6)

  • vitamin K-epoxide cycle: H+ + H2O + a [protein] 4-carboxy-L-glutamate + vitamin K 2,3-epoxide ⟶ CO2 + O2 + a [protein]-α-L-glutamate + phylloquinol
  • vitamin K-epoxide cycle: a reduced thioredoxin + phylloquinone ⟶ an oxidized thioredoxin + phylloquinol
  • menaquinol-4 biosynthesis II: H+ + NADH + menadione ⟶ NAD+ + menadiol
  • menaquinol-4 biosynthesis II: H2O + phylloquinone ⟶ menadione + phytol
  • vitamin K degradation: O2 + a reduced [NADPH-hemoprotein reductase] + phylloquinone ⟶ ω-hydroxyphylloquinone + H2O + an oxidized [NADPH-hemoprotein reductase]
  • vitamin K degradation: O2 + a reduced [NADPH-hemoprotein reductase] + phylloquinone ⟶ ω-hydroxyphylloquinone + H2O + an oxidized [NADPH-hemoprotein reductase]

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(4)

  • Vitamin K Metabolism: Carbon dioxide + Oxygen + Peptidyl-4-carboxyglutamate + Phylloquinol ⟶ Peptidyl-glutamate + Vitamin K1 2,3-epoxide + Water
  • Vitamin K Metabolism: Carbon dioxide + Oxygen + Reduced Vitamin K (phylloquinone) + Unknown ⟶ Unknown + Vitamin K1 2,3-epoxide + Water
  • Vitamin K Metabolism: Oxidized dithiothreitol + Vitamin K1 ⟶ 1,4-Dithiothreitol + Vitamin K1 2,3-epoxide
  • Vitamin K Metabolism: Oxidized dithiothreitol + Vitamin K1 ⟶ 1,4-Dithiothreitol + Vitamin K1 2,3-epoxide

PharmGKB(0)

25 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • HaoLiang Zhang, Shiqin Chen, QianYuan Zhu, ZongShan Li, Tian Lv, Chengjiang Liu. Mechanical Thrombectomy in Anticoagulated Patients With Acute Ischemic Stroke: A Meta-Analysis. The neurologist. 2024 May; 29(3):194-203. doi: 10.1097/nrl.0000000000000542. [PMID: 38019090]
  • Vasiliki Adamopoulou, Argyro Bekatorou, Vasilios Brinias, Panagiota Michalopoulou, Charalampos Dimopoulos, John Zafeiropoulos, Theano Petsi, Athanasios A Koutinas. Optimization of bacterial cellulose production by Komagataeibacter sucrofermentans in synthetic media and agrifood side streams supplemented with organic acids and vitamins. Bioresource technology. 2024 Apr; 398(?):130511. doi: 10.1016/j.biortech.2024.130511. [PMID: 38437963]
  • Diana Moldovan, Crina Rusu, Alina Potra, Dacian Tirinescu, Maria Ticala, Ina Kacso. Food to Prevent Vascular Calcification in Chronic Kidney Disease. Nutrients. 2024 Feb; 16(5):. doi: 10.3390/nu16050617. [PMID: 38474744]
  • Natália Gonçalves Silva, Marco Preto, Vitor Vasconcelos, Ralph Urbatzka. Reduction of neutral lipid reservoirs, bioconversion and untargeted metabolomics reveal distinct roles for vitamin K isoforms on lipid metabolism. Food & function. 2024 Feb; 15(4):2170-2180. doi: 10.1039/d3fo02915h. [PMID: 38312068]
  • Qiu-Yan Zhao, Qiu Li, Minoo Hasan Rashedi, Mohammadhassan Sohouli, Pejman Rohani, Periyannan Velu. The effect of vitamin K supplementation on cardiovascular risk factors: a systematic review and meta-analysis. Journal of nutritional science. 2024; 13(?):e3. doi: 10.1017/jns.2023.106. [PMID: 38282652]
  • Lenka Vlasatikova, Michal Zeman, Magdalena Crhanova, Jitka Matiasovicova, Daniela Karasova, Marcela Faldynova, Hana Prikrylova, Alena Sebkova, Ivan Rychlik. Colonization of chickens with competitive exclusion products results in extensive differences in metabolite composition in cecal digesta. Poultry science. 2024 Jan; 103(1):103217. doi: 10.1016/j.psj.2023.103217. [PMID: 37980752]
  • Ateequr Rehman, Van Pham, Nicole Seifert, Nathalie Richard, Wilbert Sybesma, Robert E Steinert. The Polyunsaturated Fatty Acids Eicosapentaenoic Acid and Docosahexaenoic Acid, and Vitamin K1 Modulate the Gut Microbiome: A Study Using an In Vitro Shime Model. Journal of dietary supplements. 2024; 21(2):135-153. doi: 10.1080/19390211.2023.2198007. [PMID: 37078491]
  • Roseani da Silva Andrade, Fabíola Isabel Suano de Souza, Carolina Sanchez Aranda, Marcia Carvalho Mallozi, Ariel Cordeiro Ferreira, Talita Lemos Neves Barreto, Fernando Luiz Affonso Fonseca, Roseli Oselka Saccardo Sarni, Dirceu Solé. Antioxidant defense of children and adolescents with atopic dermatitis: Association with disease severity. Allergologia et immunopathologia. 2024; 52(1):65-70. doi: 10.15586/aei.v52i1.933. [PMID: 38186195]
  • Anqi Chen, Jialu Li, Nianxuan Shen, Haifeng Huang, Qinglei Hang. Vitamin K: New insights related to senescence and cancer metastasis. Biochimica et biophysica acta. Reviews on cancer. 2023 Dec; 1879(2):189057. doi: 10.1016/j.bbcan.2023.189057. [PMID: 38158025]
  • Camelia Munteanu, Betty Schwartz. B Vitamins, Glucoronolactone and the Immune System: Bioavailability, Doses and Efficiency. Nutrients. 2023 Dec; 16(1):. doi: 10.3390/nu16010024. [PMID: 38201854]
  • Éva Szabó, Ildikó Csölle, Regina Felső, Daniela Kuellenberg de Gaudry, Patrick Nyamemba Nyakundi, Kazahyet Ibrahim, Maria-Inti Metzendorf, Tamás Ferenci, Szimonetta Lohner. Benefits and Harms of Edible Vegetable Oils and Fats Fortified with Vitamins A and D as a Public Health Intervention in the General Population: A Systematic Review of Interventions. Nutrients. 2023 Dec; 15(24):. doi: 10.3390/nu15245135. [PMID: 38140394]
  • Amani M Ali, Maggie M Abbassi, Nirmeen A Sabry, May Fawzi, Shrook Mousa. The effect of vitamin K4 supplementation on insulin resistance in individuals with type 2 diabetes: a double-blind randomised placebo-controlled clinical trial. European journal of nutrition. 2023 Dec; 62(8):3241-3249. doi: 10.1007/s00394-023-03215-8. [PMID: 37552330]
  • Dries S Martens, De-Wei An, Yu-Ling Yu, Babangida S Chori, Congrong Wang, Ana Inês Silva, Fang-Fei Wei, Chen Liu, Katarzyna Stolarz-Skrzypek, Marek Rajzer, Agnieszka Latosinska, Harald Mischak, Jan A Staessen, Tim S Nawrot. Association of Air Pollution with a Urinary Biomarker of Biological Aging and Effect Modification by Vitamin K in the FLEMENGHO Prospective Population Study. Environmental health perspectives. 2023 Dec; 131(12):127011. doi: 10.1289/ehp13414. [PMID: 38078706]
  • Jiameng Liu, Luqi Qin, Jiahuan Zheng, Litao Tong, Wei Lu, Cong Lu, Jing Sun, Bei Fan, Fengzhong Wang. Research Progress on the Relationship between Vitamins and Diabetes: Systematic Review. International journal of molecular sciences. 2023 Nov; 24(22):. doi: 10.3390/ijms242216371. [PMID: 38003557]
  • Karina A Pedroza-García, Gabriela Careaga-Cárdenas, Carmen Díaz-Galindo, J Luis Quintanar, Irma Hernández-Jasso, Ricardo E Ramírez-Orozco. Bioactive role of vitamins as a key modulator of oxidative stress, cellular damage and comorbidities associated with spinal cord injury (SCI). Nutritional neuroscience. 2023 Nov; 26(11):1120-1137. doi: 10.1080/1028415x.2022.2133842. [PMID: 36537581]
  • María Ciudad-Mulero, Laura Domínguez, Patricia Morales, Virginia Fernández-Ruiz, Montaña Cámara. A Review of Foods of Plant Origin as Sources of Vitamins with Proven Activity in Oxidative Stress Prevention according to EFSA Scientific Evidence. Molecules (Basel, Switzerland). 2023 Oct; 28(21):. doi: 10.3390/molecules28217269. [PMID: 37959689]
  • Alexandru Vasile Rusu, Monica Trif, João Miguel Rocha. Microbial Secondary Metabolites via Fermentation Approaches for Dietary Supplementation Formulations. Molecules (Basel, Switzerland). 2023 Aug; 28(16):. doi: 10.3390/molecules28166020. [PMID: 37630272]
  • Toshitaka Nakamura, Clara Hipp, André Santos Dias Mourão, Jan Borggräfe, Maceler Aldrovandi, Bernhard Henkelmann, Jonas Wanninger, Eikan Mishima, Elena Lytton, David Emler, Bettina Proneth, Michael Sattler, Marcus Conrad. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul; 619(7969):371-377. doi: 10.1038/s41586-023-06255-6. [PMID: 37380771]
  • Zhaofang Li, Yajing Li, Yijing Hou, Yahui Fan, Hong Jiang, Baoyu Li, Hailu Zhu, Yaning Liu, Lei Zhang, Jie Zhang, Min Wu, Tianyou Ma, Tong Zhao, Le Ma. Association of Plasma Vitamins and Carotenoids, DNA Methylation of LCAT, and Risk of Age-Related Macular Degeneration. Nutrients. 2023 Jun; 15(13):. doi: 10.3390/nu15132985. [PMID: 37447314]
  • Eikan Mishima, Adam Wahida, Tobias Seibt, Marcus Conrad. Diverse biological functions of vitamin K: from coagulation to ferroptosis. Nature metabolism. 2023 Jun; ?(?):. doi: 10.1038/s42255-023-00821-y. [PMID: 37337123]
  • Clement G Yedjou, Jameka Grigsby, Ariane Mbemi, Daryllynn Nelson, Bryan Mildort, Lekan Latinwo, Paul B Tchounwou. The Management of Diabetes Mellitus Using Medicinal Plants and Vitamins. International journal of molecular sciences. 2023 May; 24(10):. doi: 10.3390/ijms24109085. [PMID: 37240430]
  • Khushnuma Saleem, Tariq Aziz, Ayaz Ali Khan, Ali Muhammad, Shafiq Ur Rahman, Metab Alharbi, Abdulrahman Alshammari, Abdullah F Alasmari. Evaluating the in-vivo effects of olive oil, soya bean oil, and vitamins against oxidized ghee toxicity. Acta biochimica Polonica. 2023 May; 70(2):305-312. doi: 10.18388/abp.2020_6549. [PMID: 37163731]
  • Oladapo F Fagbohun, Caroline R Gillies, Kieran P J Murphy, H P Vasantha Rupasinghe. Role of Antioxidant Vitamins and Other Micronutrients on Regulations of Specific Genes and Signaling Pathways in the Prevention and Treatment of Cancer. International journal of molecular sciences. 2023 Mar; 24(7):. doi: 10.3390/ijms24076092. [PMID: 37047063]
  • Alireza Ekhlasian, Ebrahim Eftekhar, Sajedeh Daei, Roghayeh Abbasalipourkabir, Alireza Nourian, Nasrin Ziamajidi. The antioxidant and anti-apoptotic properties of vitamins A, C and E in heart tissue of rats exposed to zinc oxide nanoparticles. Molecular biology reports. 2023 Mar; 50(3):2357-2365. doi: 10.1007/s11033-022-08103-8. [PMID: 36580195]
  • Saša Đurović, Darko Micić, Saša Šorgić, Saša Popov, Uroš Gašić, Tomislav Tosti, Marija Kostić, Yulia A Smyatskaya, Stevan Blagojević, Zoran Zeković. Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. Molecules (Basel, Switzerland). 2023 Feb; 28(5):. doi: 10.3390/molecules28052278. [PMID: 36903524]
  • Jiayue Xia, Junhui Yu, Hai Xu, Yuhao Zhou, Hui Li, Shiyu Yin, Dengfeng Xu, Yuanyuan Wang, Hui Xia, Wang Liao, Shaokang Wang, Guiju Sun. Comparative effects of vitamin and mineral supplements in the management of type 2 diabetes in primary care: A systematic review and network meta-analysis of randomized controlled trials. Pharmacological research. 2023 Feb; 188(?):106647. doi: 10.1016/j.phrs.2023.106647. [PMID: 36638933]
  • Cristiane Hermes Sales, Mariane de Mello Fontanelli, Marcelo Macedo Rogero, Flávia Mori Sarti, Regina Mara Fisberg. Dietary inadequacies overestimate the blood deficiencies of magnesium, zinc, and vitamins A, C, E, and D among residents of Sao Paulo. Clinical nutrition ESPEN. 2023 02; 53(?):196-205. doi: 10.1016/j.clnesp.2022.12.015. [PMID: 36657914]
  • Sergio Moreno-Nombela, Javier Romero-Parra, Francisco Javier Ruiz-Ojeda, Patricio Solis-Urra, Aiman Tariq Baig, Julio Plaza-Diaz. Genome Editing and Protein Energy Malnutrition. Advances in experimental medicine and biology. 2023; 1396(?):215-232. doi: 10.1007/978-981-19-5642-3_15. [PMID: 36454470]
  • Chunli Fan, Tingting Feng, Xingwei Wang, Shuqin Xia, Caleb John Swing. Liposomes for encapsulation of liposoluble vitamins (A, D, E and K): Comparation of loading ability, storage stability and bilayer dynamics. Food research international (Ottawa, Ont.). 2023 01; 163(?):112264. doi: 10.1016/j.foodres.2022.112264. [PMID: 36596175]
  • Guicun Yang, Nianrong Wang, Hao Liu, Lina Si, Yan Zhao. The association between umbilical cord blood fat-soluble vitamin concentrations and infant birth weight. Frontiers in endocrinology. 2023; 14(?):1048615. doi: 10.3389/fendo.2023.1048615. [PMID: 37810886]
  • Wei-Li Kong, Xin-Rong Lu, Lin-Lin Hou, Xiu-Fa Sun, Gui-Qin Sun, Li Chen. [Vitamins and Immune System Health]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2023 Jan; 54(1):7-13. doi: 10.12182/20230160107. [PMID: 36647636]
  • Muhammad Zahoor Khan, Bingjian Huang, Xiyan Kou, Yinghui Chen, Huili Liang, Qudrat Ullah, Ibrar Muhammad Khan, Adnan Khan, Wenqiong Chai, Changfa Wang. Enhancing bovine immune, antioxidant and anti-inflammatory responses with vitamins, rumen-protected amino acids, and trace minerals to prevent periparturient mastitis. Frontiers in immunology. 2023; 14(?):1290044. doi: 10.3389/fimmu.2023.1290044. [PMID: 38259482]
  • Tommaso Cai, Luca Gallelli, Erika Cione, Paolo Verze, Alessandro Palmieri, Vincenzo Mirone, Gernot Bonkat, Florian M Wagenlehner, Truls E Bjerklund Johansen. The efficacy and tolerability of pollen extract in combination with hyaluronic acid and vitamins in the management of patients affected by chronic prostatitis/chronic pelvic pain syndrome: a 26 weeks, randomized, controlled, single-blinded, phase III study. Minerva urology and nephrology. 2022 Dec; 74(6):780-788. doi: 10.23736/s2724-6051.21.04141-2. [PMID: 33781014]
  • Huaying Song, Zhufeng Cong, Changlin Wang, Mengyuan He, Congying Liu, Peng Gao. Research progress on Walnut oil: Bioactive compounds, health benefits, extraction methods, and medicinal uses. Journal of food biochemistry. 2022 12; 46(12):e14504. doi: 10.1111/jfbc.14504. [PMID: 36369998]
  • Birgitta Ryback, Miriam Bortfeld-Miller, Julia A Vorholt. Metabolic adaptation to vitamin auxotrophy by leaf-associated bacteria. The ISME journal. 2022 12; 16(12):2712-2724. doi: 10.1038/s41396-022-01303-x. [PMID: 35987782]
  • Toshinobu Hondo, Chihiro Ota, Yumi Miyake, Hiroshi Furutani, Michisato Toyoda. Microscale supercritical fluid extraction combined with supercritical fluid chromatography and proton-transfer-reaction ionization time-of-flight mass spectrometry for a magnitude lower limit of quantitation of lipophilic compounds. Journal of chromatography. A. 2022 Oct; 1682(?):463495. doi: 10.1016/j.chroma.2022.463495. [PMID: 36126560]
  • Tal Hirschhorn, Brent R Stockwell. Vitamin K: A new guardian against ferroptosis. Molecular cell. 2022 10; 82(20):3760-3762. doi: 10.1016/j.molcel.2022.10.001. [PMID: 36270246]
  • Xinyang Li, Yingyi Mao, Shuang Liu, Jin Wang, Xiang Li, Yanrong Zhao, David R Hill, Shuo Wang. Vitamins, Vegetables and Metal Elements Are Positively Associated with Breast Milk Oligosaccharide Composition among Mothers in Tianjin, China. Nutrients. 2022 Oct; 14(19):. doi: 10.3390/nu14194131. [PMID: 36235783]
  • Melanie P Muller, James H Morrissey, Emad Tajkhorshid. Molecular View into Preferential Binding of the Factor VII Gla Domain to Phosphatidic Acid. Biochemistry. 2022 08; 61(16):1694-1703. doi: 10.1021/acs.biochem.2c00266. [PMID: 35853076]
  • Vincenzo Russo, Roberta Bottino, Antonello D'Andrea, Angelo Silverio, Marco Di Maio, Paolo Golino, Gerardo Nigro, Orazio Valsecchi, Emilio Attena, Mario Enrico Canonico, Gennaro Galasso, Guido Parodi, Fernando Scudiero. Chronic Oral Anticoagulation and Clinical Outcome in Hospitalized COVID-19 Patients. Cardiovascular drugs and therapy. 2022 Aug; 36(4):705-712. doi: 10.1007/s10557-021-07194-y. [PMID: 33988835]
  • Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-Ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A Pratt, Marcus Conrad. A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature. 2022 08; 608(7924):778-783. doi: 10.1038/s41586-022-05022-3. [PMID: 35922516]
  • Shaughn Nalezinski. Methods to Correct Drug-Induced Coagulopathy in Bleeding Emergencies: A Comparative Review. Laboratory medicine. 2022 Jul; 53(4):336-343. doi: 10.1093/labmed/lmab115. [PMID: 35073576]
  • Lin Li, Min Dai, Yingying Fu. Non-vitamin K antagonist oral anticoagulants (NOACs) in preventing thromboembolism in atrial fibrillation patients with moderate to severe mitral stenosis: Results from a pilot trial. International journal of cardiology. 2022 07; 358(?):58. doi: 10.1016/j.ijcard.2022.04.029. [PMID: 35417739]
  • Sajidah Alkhameys, Ravina Barrett. Impact of the COVID-19 pandemic on England's national prescriptions of oral vitamin K antagonist (VKA) and direct-acting oral anticoagulants (DOACs): an interrupted time series analysis (January 2019-February 2021). Current medical research and opinion. 2022 Jul; 38(7):1081-1092. doi: 10.1080/03007995.2022.2078100. [PMID: 35582854]
  • Bodil Roth, Ewa Larsson, Bodil Ohlsson. Poor intake of vitamins and minerals is associated with symptoms among patients with irritable bowel syndrome. Journal of gastroenterology and hepatology. 2022 Jul; 37(7):1253-1262. doi: 10.1111/jgh.15830. [PMID: 35304769]
  • Nicole E Lock, Alexandra A Sawyer, Linda Wise, Jatinder Bhatia, Brian K Stansfield. Vitamin K and ECMO for neonatal hypoxic respiratory failure. Perfusion. 2022 07; 37(5):484-492. doi: 10.1177/02676591211003870. [PMID: 33761796]
  • Takahiro Sakai, Hirohiko Motoki, Aya Fuchida, Takahiro Takeuchi, Kyuhachi Otagiri, Masafumi Kanai, Kazuhiro Kimura, Masatoshi Minamisawa, Koji Yoshie, Tatsuya Saigusa, Soichiro Ebisawa, Ayako Okada, Hiroshi Kitabayashi, Koichiro Kuwahara. Comparison of prognostic impact of anticoagulants in heart failure patients with atrial fibrillation and renal dysfunction: direct oral anticoagulants versus vitamin K antagonists. Heart and vessels. 2022 Jul; 37(7):1232-1241. doi: 10.1007/s00380-022-02027-w. [PMID: 35064298]
  • Karin Willeit, Peter Santer, Lena Tschiderer, Raimund Pechlaner, Cees Vermeer, Johann Willeit, Stefan Kiechl. Association of desphospho-uncarboxylated matrix gla protein with incident cardiovascular disease and all-cause mortality: Results from the prospective Bruneck Study. Atherosclerosis. 2022 07; 353(?):20-27. doi: 10.1016/j.atherosclerosis.2022.06.1017. [PMID: 35764030]
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  • Andreas Meinitzer, Dietmar Enko, Sieglinde Zelzer, Florian Prüller, Nerea Alonso, Eva Fritz-Petrin, Markus Herrmann. Development of a liquid chromatography mass spectrometry method for the determination of vitamin K1, menaquinone-4, menaquinone-7 and vitamin K1-2,3 epoxide in serum of individuals without vitamin K supplements. Clinical chemistry and laboratory medicine. 2022 06; 60(7):1011-1019. doi: 10.1515/cclm-2022-0192. [PMID: 35427444]
  • Daan Kremer, Dion Groothof, Charlotte A Keyzer, Coby Eelderink, Tim J Knobbe, Adrian Post, Marco van Londen, Michele F Eisenga, TransplantLines Investigators, Leon J Schurgers, Stefan P Berger, Martin H de Borst, Stephan J L Bakker. Reply to Janssen et al. Comment on 'Kremer et al. Kidney Function-Dependence of Vitamin K-Status Parameters: Results from the TransplantLines Biobank and Cohort Studies. Nutrients 2021, 13, 3069'. Nutrients. 2022 Jun; 14(12):. doi: 10.3390/nu14122440. [PMID: 35745170]
  • Rob Janssen, Jona Walk, Cees Vermeer. Comment on Kremer et al. Kidney Function-Dependence of Vitamin K-Status Parameters: Results from the TransplantLines Biobank and Cohort Studies. Nutrients 2021, 13, 3069. Nutrients. 2022 Jun; 14(12):. doi: 10.3390/nu14122439. [PMID: 35745169]
  • Cheng Xu, Yang Cunqing, Gu Chun, Wu Min, Li Jun, Hou Xueyun, Fei Jiaxin, Sun Li, An Cheng, Liu Guijian, Shi Fengxiang, Pang Bo. The relationship between serum vitamin K concentration and coronary artery calcification in middle-aged and elderly people. Clinica chimica acta; international journal of clinical chemistry. 2022 Jun; 531(?):325-330. doi: 10.1016/j.cca.2022.04.1001. [PMID: 35504322]
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