L-Norleucine (BioDeep_00000001869)
Secondary id: BioDeep_00000399976, BioDeep_00000400248, BioDeep_00000897205, BioDeep_00001890546
natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 Volatile Flavor Compounds
代谢物信息卡片
化学式: C6H13NO2 (131.0946238)
中文名称: L-正亮氨酸, 正亮氨酸, DL-正亮氨酸, L-2-氨基己酸
谱图信息:
最多检出来源 Homo sapiens(blood) 0.34%
Last reviewed on 2024-07-04.
Cite this Page
L-Norleucine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/l-norleucine (retrieved
2024-11-24) (BioDeep RN: BioDeep_00000001869). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CCCCC(C(=O)O)N
InChI: InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)
描述信息
L-Norleucine, also known as L-aminohexanoate or caprine, belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. Thus, L-norleucine is considered to be a fatty acid lipid molecule. An unnatural amino acid that is used experimentally to study protein structure and function. L-Norleucine is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. L-Norleucine exists in all eukaryotes, ranging from yeast to humans. Outside of the human body, L-Norleucine has been detected, but not quantified in cow milk. This could make L-norleucine a potential biomarker for the consumption of these foods. It binds reversibly to the kringle domain of plasminogen and blocks the binding of plasminogen to fibrin and its activation to plasmin.
An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to methionine, however it does not contain sulfur.
Acquisition and generation of the data is financially supported in part by CREST/JST.
CONFIDENCE standard compound; INTERNAL_ID 22
KEIO_ID N014
L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
同义名列表
39 个代谢物同义名
(S)-2-amino-Hexanoic acid; (2S)-2-aminohexanoic acid; (S)-2-Aminohexanoic acid; alpha-Aminocaproic acid; 2S-amino-hexanoic acid; L-2-Aminohexanoic acid; (S)-Aminohexanoic acid; (S)-2-amino-Hexanoate; Norleucine, L-isomer; 2-Aminohexanoic acid; Norleucine, L isomer; L-Aminohexanoic acid; (S)-2-Aminohexanoate; 2-Aminocaproic acid; L-Isomer norleucine; Α-aminocaproic acid; alpha-Aminocaproate; a-Aminocaproic acid; 2S-Amino-hexanoate; L-2-Aminohexanoate; (S)-Aminohexanoate; L-Aminohexanoate; 2-Aminohexanoate; L-(+)-Norleucine; 2-Aminocaproate; a-Aminocaproate; Α-aminocaproate; L(+)-Norleucine; (S)-Norleucine; DL-Norleucine; L-Norleucine; Glycoleucine; H-DL-Nle-OH; Norleucine; Caprine; Nle; L-Norleucine; Norleucine; L-Norleucine
数据库引用编号
44 个数据库交叉引用编号
- ChEBI: CHEBI:18347
- ChEBI: CHEBI:36405
- KEGG: C01933
- PubChem: 21236
- PubChem: 9475
- HMDB: HMDB0001645
- Metlin: METLIN6334
- DrugBank: DB15458
- ChEMBL: CHEMBL292439
- Wikipedia: Norleucine
- LipidMAPS: LMFA01100042
- MeSH: Norleucine
- MetaCyc: L-2-AMINOHEXANOATE
- KNApSAcK: C00053319
- foodb: FDB022699
- chemspider: 19964
- CAS: 327-57-1
- MoNA: PR100583
- MoNA: KO003598
- MoNA: KO001520
- MoNA: KO003601
- MoNA: KO001521
- MoNA: KO001522
- MoNA: PR100169
- MoNA: RP002211
- MoNA: KO003600
- MoNA: RP002201
- MoNA: PS028301
- MoNA: PR100170
- MoNA: PS028304
- MoNA: RP002202
- MoNA: PS028302
- MoNA: RP002203
- MoNA: KO003599
- MoNA: PS028303
- MoNA: KO003597
- PMhub: MS000001343
- PDB-CCD: NLE
- 3DMET: B00369
- NIKKAJI: J9.189H
- medchemexpress: HY-Y0017
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-307
- PubChem: 5038
- KNApSAcK: 18347
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
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Organic & biomolecular chemistry.
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2011 Dec; 7(?):81. doi:
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Veterinary parasitology.
2011 Dec; 182(2-4):239-47. doi:
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Environmental entomology.
2011 Dec; 40(6):1572-6. doi:
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Acta veterinaria Scandinavica.
2011 Nov; 53(?):60. doi:
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Theriogenology.
2011 Sep; 76(5):933-41. doi:
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Emerging infectious diseases.
2011 Sep; 17(9):1630-5. doi:
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The Korean journal of parasitology.
2011 Sep; 49(3):213-9. doi:
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BMC veterinary research.
2011 Jul; 7(?):34. doi:
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Acta veterinaria Scandinavica.
2011 Jun; 53(?):37. doi:
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Journal of food protection.
2011 Jun; 74(6):919-24. doi:
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The Korean journal of parasitology.
2011 Jun; 49(2):133-8. doi:
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Nutrients.
2011 05; 3(5):574-603. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
2011 Apr; 108(15):6103-8. doi:
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Journal of enzyme inhibition and medicinal chemistry.
2011 Apr; 26(2):155-61. doi:
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Parasites & vectors.
2011 Apr; 4(?):47. doi:
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Parasites & vectors.
2011 Mar; 4(?):36. doi:
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Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2011 Mar; 42(1):33-9. doi:
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Australian veterinary journal.
2011 Mar; 89(3):95-100. doi:
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Molecular biology reports.
2011 Mar; 38(3):1621-8. doi:
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Revista de biologia tropical.
2011 Mar; 59(1):37-52. doi:
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Reproductive biology and endocrinology : RB&E.
2011 Jan; 9(?):3. doi:
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International journal of microbiology.
2011; 2011(?):248418. doi:
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Journal of parasitology research.
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The Plant cell.
2011 Jan; 23(1):38-53. doi:
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Frontiers in plant science.
2011; 2(?):36. doi:
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Molecular biology and evolution.
2011 Jan; 28(1):377-82. doi:
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Journal of amino acids.
2011; 2011(?):107179. doi:
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Journal of amino acids.
2011; 2011(?):198430. doi:
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PloS one.
2010 Dec; 5(12):e15716. doi:
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Veterinary medicine international.
2010 Dec; 2011(?):670987. doi:
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Animal : an international journal of animal bioscience.
2010 Dec; 4(12):1953-7. doi:
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Biochemistry.
2010 Oct; 49(42):9046-57. doi:
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Veterinary parasitology.
2010 Oct; 173(1-2):2-10. doi:
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Biochemical genetics.
2010 Oct; 48(9-10):822-8. doi:
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BMC musculoskeletal disorders.
2010 Sep; 11(?):220. doi:
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Virology journal.
2010 Sep; 7(?):245. doi:
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PloS one.
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Transgenic research.
2010 Aug; 19(4):563-74. doi:
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The British journal of nutrition.
2010 Aug; 104(3):346-54. doi:
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The Journal of nutrition.
2010 Aug; 140(8):1418-24. doi:
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Memorias do Instituto Oswaldo Cruz.
2010 Aug; 105(5):698-705. doi:
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The British journal of nutrition.
2010 Aug; 104(3):374-81. doi:
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Nutrition & metabolism.
2010 Jul; 7(?):58. doi:
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Nutrition & metabolism.
2010 Jul; 7(?):57. doi:
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Genome biology and evolution.
2010 Jul; 2(?):454-66. doi:
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Animal : an international journal of animal bioscience.
2010 Jul; 4(7):1140-66. doi:
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European journal of nuclear medicine and molecular imaging.
2010 Jul; 37(7):1386-96. doi:
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