3-Hydroxybenzaldehyde (BioDeep_00000000733)

 

Secondary id: BioDeep_00000868586

natural product PANOMIX_OTCML-2023 Cytotoxicity BioNovoGene_Lab2019


代谢物信息卡片


Benzaldehyde, 3-hydroxy-

化学式: C7H6O2 (122.0368)
中文名称: 间羟基苯甲醛, 3-羟基苯甲醛
谱图信息: 最多检出来源 Viridiplantae(plant) 10.8%

Reviewed

Last reviewed on 2024-08-06.

Cite this Page

3-Hydroxybenzaldehyde. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/3-hydroxybenzaldehyde (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000733). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=CC(=C1)O)C=O
InChI: InChI=1S/C7H6O2/c8-5-6-2-1-3-7(9)4-6/h1-5,9H

描述信息

3-hydroxybenzaldehyde is a hydroxybenzaldehyde carrying a hydroxy substituent at position 3.
3-Hydroxybenzaldehyde is a natural product found in Rhytidoponera metallica, Marchantia polymorpha, and other organisms with data available.

3-Hydroxybenzaldehyde, also known as 3-hydroxybenzaldehyde or m-hydroxybenzaldehyde, is an organic compound belonging to the class of aromatic aldehydes. Its chemical formula is C7H6O2 and it is characterized by a benzene ring with a hydroxyl group (-OH) and an aldehyde group (-CHO) attached at the meta position on the ring.
Biologically, 3-hydroxybenzaldehyde has been found to possess several interesting properties:
1. **Antioxidant Activity**: It exhibits antioxidant properties, which means it can neutralize harmful free radicals in the body. This can be beneficial in reducing oxidative stress, which is associated with various diseases and aging.
2. **Antimicrobial Effects**: 3-Hydroxybenzaldehyde has shown antimicrobial activity against a range of microorganisms, including bacteria and fungi. This makes it a potential candidate for the development of new antimicrobial agents.
3. **Anti-inflammatory Properties**: Some studies have indicated that this compound may have anti-inflammatory effects, which could be useful in the treatment of inflammatory conditions.
4. **Cytotoxicity**: It has been observed to have cytotoxic effects on certain types of cancer cells, suggesting a potential role in cancer therapy. However, more research is needed in this area.
5. **Enzyme Inhibition**: 3-Hydroxybenzaldehyde can inhibit the activity of certain enzymes, which may have implications in the management of conditions where these enzymes play a pathological role.
It's important to note that while 3-hydroxybenzaldehyde has these biological properties, its use in practical applications, especially in a medical context, is still largely experimental and requires further research. The compound's effects and safety profile need to be thoroughly evaluated before it can be considered for widespread use in therapeutic or preventive treatments.

3-Hydroxybenzaldehyde. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=100-83-4 (retrieved 2024-08-06) (CAS RN: 100-83-4). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
3-Hydroxybenzaldehyde?is a precursor compound for phenolic compounds, such as Protocatechualdehyde (HY-N0295). 3-Hydroxybenzaldehyde is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans (ALDH2). 3-Hydroxybenzaldehyde has vasculoprotective effects?in vitro and in vivo[1].
3-Hydroxybenzaldehyde?is a precursor compound for phenolic compounds, such as Protocatechualdehyde (HY-N0295). 3-Hydroxybenzaldehyde is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans (ALDH2). 3-Hydroxybenzaldehyde has vasculoprotective effects?in vitro and in vivo[1].
3-Hydroxybenzaldehyde?is a precursor compound for phenolic compounds, such as Protocatechualdehyde (HY-N0295). 3-Hydroxybenzaldehyde is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans (ALDH2). 3-Hydroxybenzaldehyde has vasculoprotective effects?in vitro and in vivo[1].

同义名列表

27 个代谢物同义名

3-Hydroxybenzaldehyde, purum, >=95.0\\% (HPLC), faintly yellow to light brown; 4-08-00-00240 (Beilstein Handbook Reference); InChI=1/C7H6O2/c8-5-6-2-1-3-7(9)4-6/h1-5,9; (3-hydroxyphenyl) formaldehyde; 3-Hydroxybenzaldehyde, >=99\\%; (3-hydroxyphenyl)methanone; Benzaldehyde, 3-hydroxy-; Benzaldehyde, m-hydroxy-; meta-hydroxybenzaldehyde; HYDROXYBENZALDEHYDE. 3-; 3-hydroxy benzoaldehyde; m-hydroxy benzaldehyde; 3-oxidanylbenzaldehyde; 3-HYDROXY-BENZALDEHYDE; 3-hydroxy benzaldehyde; 3-hydroxylbenzaldehyde; m-hydroxybenzaldehyde; 3-Hydroxybenzaldehyde; 3-Hydroxybenzaldehyd; UNII-8Z2819J40E; 3-Formylphenol; m-Formylphenol; 8Z2819J40E; AI3-12120; 3-Hydroxybenzaldehyde; 3-Hydroxybenzaldehyde; 3-Hydroxybenzaldehyde



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

36 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • N Aissani, R Aissani, F Zouidi, H Sebai. Nematicidal activity of o-hydroxybenzaldehyde from common buckwheat methanol extract on Meloidogyne incognita. Journal of helminthology. 2023 Jul; 97(?):e60. doi: 10.1017/s0022149x23000457. [PMID: 37492936]
  • Stephen S Nyandoro, Joan J E Munissi, Amra Gruhonjic, Sandra Duffy, Fangfang Pan, Rakesh Puttreddy, John P Holleran, Paul A Fitzpatrick, Jerry Pelletier, Vicky M Avery, Kari Rissanen, Máté Erdélyi. Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves. Journal of natural products. 2017 01; 80(1):114-125. doi: 10.1021/acs.jnatprod.6b00759. [PMID: 28001067]
  • Md Iqbal Alam, Mohammed A Alam, Ozair Alam, Amit Nargotra, Subhash Chandra Taneja, Surrinder Koul. Molecular modeling and snake venom phospholipase A2 inhibition by phenolic compounds: Structure-activity relationship. European journal of medicinal chemistry. 2016 May; 114(?):209-19. doi: 10.1016/j.ejmech.2016.03.008. [PMID: 26986086]
  • Pierluigi Caboni, Nadhem Aissani, Tiziana Cabras, Andrea Falqui, Roberto Marotta, Barbara Liori, Nikoletta Ntalli, Giorgia Sarais, Nicola Sasanelli, Graziella Tocco. Potent nematicidal activity of phthalaldehyde, salicylaldehyde, and cinnamic aldehyde against Meloidogyne incognita. Journal of agricultural and food chemistry. 2013 Feb; 61(8):1794-803. doi: 10.1021/jf305164m. [PMID: 23379671]
  • Vanisree Mulabagal, Ruby L Alexander-Lindo, David L Dewitt, Muraleedharan G Nair. Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):601249. doi: 10.1093/ecam/nep041. [PMID: 19454555]
  • Chao-Bin Xue, Li Zhang, Wan-Chun Luo, Xian-Ye Xie, Lin Jiang, Ting Xiao. 3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors. Bioorganic & medicinal chemistry. 2007 Mar; 15(5):2006-15. doi: 10.1016/j.bmc.2006.12.038. [PMID: 17258462]