2-Naphthaldehyde (BioDeep_00000009687)

 

Secondary id: BioDeep_00001874203

human metabolite natural product


代谢物信息卡片


2-Naphthalenecarboxaldehyde

化学式: C11H8O (156.0575)
中文名称: 2-萘甲醛, 2-萘
谱图信息: 最多检出来源 Homo sapiens(blood) 39.74%

分子结构信息

SMILES: C1=CC=C2C=C(C=CC2=C1)C=O
InChI: InChI=1S/C11H8O/c12-8-9-5-6-10-3-1-2-4-11(10)7-9/h1-8H

描述信息

This compound belongs to the family of Naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.

同义名列表

12 个代谢物同义名

2-Naphthalenecarboxaldehyde; naphthalene-2-carbaldehyde; beta-Formylnaphthalene; beta-Naphthaldehyde; Β-formylnaphthalene; 2-Formylnaphthalene; b-Formylnaphthalene; 2-Naphthaldehyde; Β-naphthaldehyde; b-Naphthaldehyde; 2-Naphthaldehyde; 2-Naphthaldehyde



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ANXA5, BCL2, CASP3, FGFR4, PLA2G12A, TUBB4B
Peripheral membrane protein 2 ANXA5, CYP1B1
Endoplasmic reticulum membrane 2 BCL2, CYP1B1
Nucleus 3 BCL2, CASP3, TUBB4B
cytosol 4 ANXA5, BCL2, CASP3, TUBB4B
nucleoplasm 1 CASP3
Cell membrane 2 FGFR4, OPRD1
Multi-pass membrane protein 1 OPRD1
glutamatergic synapse 1 CASP3
Golgi apparatus 1 FGFR4
lysosomal membrane 1 GAA
neuronal cell body 1 CASP3
presynaptic membrane 1 OPRD1
sarcolemma 1 ANXA5
Lysosome 1 GAA
endosome 1 FGFR4
plasma membrane 3 FGFR4, GAA, OPRD1
synaptic vesicle membrane 1 OPRD1
Membrane 7 ANXA5, BCL2, CYP1B1, ENTPD5, FGFR4, GAA, OPRD1
extracellular exosome 3 ANXA5, GAA, TUBB4B
Lysosome membrane 1 GAA
endoplasmic reticulum 3 BCL2, ENTPD5, FGFR4
extracellular space 1 ENTPD5
lysosomal lumen 1 GAA
mitochondrion 2 BCL2, CYP1B1
protein-containing complex 1 BCL2
intracellular membrane-bounded organelle 2 CYP1B1, GAA
Microsome membrane 1 CYP1B1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 FGFR4
Secreted 3 ENTPD5, GAA, PLA2G12A
extracellular region 6 ANXA5, ENTPD5, FGFR4, GAA, PLA2G12A, TUBB4B
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 ANXA5
Extracellular vesicle 1 TUBB4B
microtubule cytoskeleton 1 TUBB4B
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 ANXA5
microtubule 1 TUBB4B
collagen-containing extracellular matrix 1 ANXA5
receptor complex 1 FGFR4
Zymogen granule membrane 1 ANXA5
neuron projection 1 OPRD1
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
axonemal microtubule 1 TUBB4B
tertiary granule membrane 1 GAA
myelin sheath 1 BCL2
axon terminus 1 OPRD1
transport vesicle 1 FGFR4
azurophil granule membrane 1 GAA
azurophil granule lumen 1 TUBB4B
postsynaptic density membrane 1 OPRD1
neuronal dense core vesicle 1 OPRD1
vesicle membrane 1 ANXA5
ficolin-1-rich granule membrane 1 GAA
death-inducing signaling complex 1 CASP3
dendrite membrane 1 OPRD1
endothelial microparticle 1 ANXA5
autolysosome lumen 1 GAA
BAD-BCL-2 complex 1 BCL2
spine apparatus 1 OPRD1


文献列表

  • Simone K Huber, Georg Höfner, Klaus T Wanner. Application of the concept of oxime library screening by mass spectrometry (MS) binding assays to pyrrolidine-3-carboxylic acid derivatives as potential inhibitors of γ-aminobutyric acid transporter 1 (GAT1). Bioorganic & medicinal chemistry. 2019 07; 27(13):2753-2763. doi: 10.1016/j.bmc.2019.05.001. [PMID: 31097402]
  • Felix Kern, Klaus T Wanner. Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors γ-aminobutyric acid transporter 1. Bioorganic & medicinal chemistry. 2019 04; 27(7):1232-1245. doi: 10.1016/j.bmc.2019.02.015. [PMID: 30777661]
  • Pierluigi Caboni, Nadhem Aissani, Tiziana Cabras, Andrea Falqui, Roberto Marotta, Barbara Liori, Nikoletta Ntalli, Giorgia Sarais, Nicola Sasanelli, Graziella Tocco. Potent nematicidal activity of phthalaldehyde, salicylaldehyde, and cinnamic aldehyde against Meloidogyne incognita. Journal of agricultural and food chemistry. 2013 Feb; 61(8):1794-803. doi: 10.1021/jf305164m. [PMID: 23379671]
  • Fernanda Spezia Pedrini, Louise Domeneghini Chiaradia, Marley Aparecida Licínio, Ana Carolina Rabello de Moraes, Juliana Costa Curta, Aline Costa, Alessandra Mascarello, Tânia Beatriz Creczinsky-Pasa, Ricardo José Nunes, Rosendo Augusto Yunes, Maria Cláudia Santos-Silva. Induction of apoptosis and cell cycle arrest in L-1210 murine lymphoblastic leukaemia cells by (2E)-3-(2-naphthyl)-1-(3'-methoxy-4'-hydroxy-phenyl)-2-propen-1-one. The Journal of pharmacy and pharmacology. 2010 Sep; 62(9):1128-36. doi: 10.1111/j.2042-7158.2010.01141.x. [PMID: 20796191]