Everninomycin (BioDeep_00000009063)
代谢物信息卡片
化学式: C70H97Cl2NO38 (1629.5065)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(CC(O1)OC2C(OC3(CC2O)OC4C(OC(C(C4(O3)C)O)OC5C(C(OC(C5OC)C)OC6C(OC(C(C6O)OC)OC7C(C8C(CO7)OC9(O8)C1C(C(CO9)OC(=O)C2=C(C=C(C=C2C)O)O)OCO1)O)COC)O)C)C)OC1CC(C(C(O1)C)OC)(C)[N+](=O)[O-])OC(=O)C1=C(C(=C(C(=C1OC)Cl)O)Cl)C
InChI: InChI=1S/C70H97Cl2NO38/c1-24-15-31(74)16-32(75)40(24)61(82)100-36-22-94-70(60-53(36)92-23-93-60)108-37-21-91-63(46(79)52(37)109-70)106-65-56(89-13)45(78)51(35(101-65)20-86-10)104-64-47(80)55(50(87-11)27(4)97-64)105-66-57(81)68(9)59(30(7)98-66)110-69(111-68)18-33(76)48(28(5)107-69)102-38-17-34(99-39-19-67(8,73(84)85)58(90-14)29(6)96-39)49(26(3)95-38)103-62(83)41-25(2)42(71)44(77)43(72)54(41)88-12/h15-16,26-30,33-39,45-53,55-60,63-66,74-81H,17-23H2,1-14H3/t26-,27-,28-,29+,30-,33-,34-,35-,36-,37+,38+,39-,45+,46-,47-,48-,49-,50+,51?,52-,53+,55+,56?,57-,58+,59-,60-,63+,64+,65+,66+,67+,68-,69?,70-/m1/s1
描述信息
同义名列表
4 个代谢物同义名
Everninomycin; b-D-Mannopyranoside,O-(1R)-4-O-(2,4-dihydroxy-6-methylbenzoyl)-2,3-O-methylene-D-xylopyranosylidene-(1?3-4)-a-L-lyxopyranosyl O-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-a-L-arabino-hexopyranosyl-(1?3)-O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-; Everninomicin; Everninomycin
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:29581
- KEGG: C12050
- PubChem: 443597
- Metlin: METLIN69276
- CAS: 53024-98-9
- PMhub: MS000022800
- PubChem: 14205
- NIKKAJI: J1.666.373E
- KNApSAcK: 29581
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- John W Davis, Federico M Goodsaid, Christopher M Bral, Leslie A Obert, George Mandakas, C Edwin Garner, Nathaniel D Collins, Roger J Smith, I Y Rosenblum. Quantitative gene expression analysis in a nonhuman primate model of antibiotic-induced nephrotoxicity.
Toxicology and applied pharmacology.
2004 Oct; 200(1):16-26. doi:
10.1016/j.taap.2004.02.001. [PMID: 15451304] - Satoru Nagashima, Masayuki Niwa, Katsuyuki Nishiki, Tatsuo Hosoya, Akira Hishida, Toshihiko Uematsu. Effects of SCH27899 (Ziracin), an oligosaccharide everninomicin antibiotic, on urate kinetics in humans.
European journal of clinical pharmacology.
2004 Jun; 60(4):255-64. doi:
10.1007/s00228-004-0755-y. [PMID: 15088132] - Ruyun Zhong, Abraham Hernandez, Kevin B Alton, Narendra S Kishnani, James E Patrick. High-performance liquid chromatographic method for the quantification of unbound evernimicin in human plasma ultrafiltrate.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2002 May; 772(1):191-5. doi:
10.1016/s1570-0232(02)00084-3. [PMID: 12016032] - O Kozawa, T Uematsu, H Matsuno, M Niwa, K Kohno, A Kawato, K Takahashi, S Nagashima, M Kanamaru. Pharmacokinetics of a new parenteral oligosaccharide antibiotic, SCH27899 (Ziracin), in healthy subjects.
Antimicrobial agents and chemotherapy.
2001 Mar; 45(3):917-21. doi:
10.1128/aac.45.3.917-921.2001. [PMID: 11181380] - E Wang, M Simard, Y Bergeron, D Beauchamp, M G Bergeron. In vivo activity and pharmacokinetics of ziracin (SCH27899), a new long-acting everninomicin antibiotic, in a murine model of penicillin-susceptible or penicillin-resistant pneumococcal pneumonia.
Antimicrobial agents and chemotherapy.
2000 Apr; 44(4):1010-8. doi:
10.1128/aac.44.4.1010-1018.2000. [PMID: 10722505] - C Lin, S Gupta, D Loebenberg, M N Cayen. Pharmacokinetics of an everninomicin (SCH 27899) in mice, rats, rabbits, and cynomolgus monkeys following intravenous administration.
Antimicrobial agents and chemotherapy.
2000 Apr; 44(4):916-9. doi:
10.1128/aac.44.4.916-919.2000. [PMID: 10722491] - C C Lin, C Korduba, D Parker. Simple and sensitive high-performance liquid chromatographic method for the determination of an everninomycin, SCH 27899, in rat plasma.
Journal of chromatography. B, Biomedical sciences and applications.
1999 Jun; 730(1):55-9. doi:
10.1016/s0378-4347(99)00204-2. [PMID: 10437672] - W E Sanders, C C Sanders. Microbiological characterization of everninomicins B and D.
Antimicrobial agents and chemotherapy.
1974 Sep; 6(3):232-8. doi:
10.1128/aac.6.3.232. [PMID: 15830468]
