Etorphine (BioDeep_00000008875)
Volatile Flavor Compounds
代谢物信息卡片
6,14-Ethenomorphinan-7-methanol, 4,5-epoxy-3-hydroxy-6-methoxy-alpha,17-dimethyl-alpha-propyl-, (5alpha,7alpha(R))-
化学式: C25H33NO4 (411.2409458000001)
中文名称: 乙烯啡
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC(C)(C1CC23C=CC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)C)OC)O
InChI: InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist
D002491 - Central Nervous System Agents > D000700 - Analgesics
Same as: D07937
同义名列表
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:4912
- KEGG: C11793
- KEGGdrug: D07937
- PubChem: 644209
- PubChem: 443407
- PubChem: 26721
- PubChem: 518962
- Metlin: METLIN69223
- DrugBank: DB01497
- ChEMBL: CHEMBL140050
- ChEMBL: CHEMBL4759736
- MeSH: Etorphine
- CAS: 14521-96-1
- PMhub: MS000022579
- MetaboLights: MTBLC4912
- PubChem: 13957
- NIKKAJI: J21.212A
- KNApSAcK: 4912
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Tithipong Plangsangmas, Hathaipat Rattanathanya, Wanlaya Tipkantha, Saowaphang Sanannu, Umaporn Maikaew, Jessada Thaeonoen, Bencharong Sangkharak, Pornpiroon Chinson, Watcharin Hin-On, Nathavut Kanatiyanont, Boripat Siriaroonrat, Nantarika Chansue, Parntep Ratanakorn. Immobilization of captive plains zebras (Equus quagga) with a combination of etorphine hydrochloride, acepromazine, and xylazine hydrochloride.
The Journal of veterinary medical science.
2022 Jan; 84(1):181-185. doi:
10.1292/jvms.21-0458. [PMID: 34866094] - Erik Olofsen, Merel Boom, Elise Sarton, Monique van Velzen, Paul Baily, Kevin J Smith, Alexander Oksche, Albert Dahan, Marieke Niesters. Analgesic and Respiratory Depressant Effects of R-dihydroetorphine: A Pharmacokinetic-Pharmacodynamic Analysis in Healthy Male Volunteers.
Anesthesiology.
2019 12; 131(6):1327-1339. doi:
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Australian veterinary journal.
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2011 07; 8(7):2569-83. doi:
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BMC plant biology.
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Nutrition & metabolism.
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BMC cell biology.
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Molecular pharmacology.
2011 Feb; 79(2):326-35. doi:
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2011; 12(3):2019-35. doi:
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PloS one.
2011; 6(9):e25271. doi:
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PloS one.
2011; 6(9):e24234. doi:
10.1371/journal.pone.0024234. [PMID: 21915303] - Joanne Canonne, Daniel Marino, Laurent D Noël, Ignacio Arechaga, Carole Pichereaux, Michel Rossignol, Dominique Roby, Susana Rivas. Detection and functional characterization of a 215 amino acid N-terminal extension in the Xanthomonas type III effector XopD.
PloS one.
2010 Dec; 5(12):e15773. doi:
10.1371/journal.pone.0015773. [PMID: 21203472] - Chrisostom Ayebazibwe, Frank N Mwiine, Kirsten Tjørnehøj, Sheila N Balinda, Vincent B Muwanika, Anna R Ademun Okurut, Graham J Belsham, Preben Normann, Hans R Siegismund, Soren Alexandersen. The role of African buffalos (Syncerus caffer) in the maintenance of foot-and-mouth disease in Uganda.
BMC veterinary research.
2010 Dec; 6(?):54. doi:
10.1186/1746-6148-6-54. [PMID: 21143994] - Shaun P Murphy, Carl R Simmons, Hank W Bass. Structure and expression of the maize (Zea mays L.) SUN-domain protein gene family: evidence for the existence of two divergent classes of SUN proteins in plants.
BMC plant biology.
2010 Dec; 10(?):269. doi:
10.1186/1471-2229-10-269. [PMID: 21143845] - Phaik Har Yong, Hongliang Zong, Reinhold J Medina, G Astrid Limb, Koji Uchida, Alan W Stitt, Tim M Curtis. Evidence supporting a role for N-(3-formyl-3,4-dehydropiperidino)lysine accumulation in Müller glia dysfunction and death in diabetic retinopathy.
Molecular vision.
2010 Dec; 16(?):2524-38. doi:
NULL. [PMID: 21151599] - L A Sikkink, M Ramirez-Alvarado. Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture.
Cell death & disease.
2010 Nov; 1(?):e98. doi:
10.1038/cddis.2010.75. [PMID: 21368874] - Monika Janczarek, Jolanta Kutkowska, Tomasz Piersiak, Anna Skorupska. Rhizobium leguminosarum bv. trifolii rosR is required for interaction with clover, biofilm formation and adaptation to the environment.
BMC microbiology.
2010 Nov; 10(?):284. doi:
10.1186/1471-2180-10-284. [PMID: 21070666] - Chi-Chou Chiu, Lih-Jen Chen, Hsou-min Li. Pea chloroplast DnaJ-J8 and Toc12 are encoded by the same gene and localized in the stroma.
Plant physiology.
2010 Nov; 154(3):1172-82. doi:
10.1104/pp.110.161224. [PMID: 20841453] - Malick Mbengue, Sylvie Camut, Fernanda de Carvalho-Niebel, Laurent Deslandes, Solène Froidure, Dörte Klaus-Heisen, Sandra Moreau, Susana Rivas, Ton Timmers, Christine Hervé, Julie Cullimore, Benoit Lefebvre. The Medicago truncatula E3 ubiquitin ligase PUB1 interacts with the LYK3 symbiotic receptor and negatively regulates infection and nodulation.
The Plant cell.
2010 Oct; 22(10):3474-88. doi:
10.1105/tpc.110.075861. [PMID: 20971894] - Laura A Engel, Zheng Jing, Daniel E O'Brien, Mengyang Sun, Paul T Kotzbauer. Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism.
PloS one.
2010 Sep; 5(9):e12897. doi:
10.1371/journal.pone.0012897. [PMID: 20886109] - Wei Zeng, Nan Jiang, Ramya Nadella, Tara L Killen, Vijayanand Nadella, Ahmed Faik. A glucurono(arabino)xylan synthase complex from wheat contains members of the GT43, GT47, and GT75 families and functions cooperatively.
Plant physiology.
2010 Sep; 154(1):78-97. doi:
10.1104/pp.110.159749. [PMID: 20631319] - Lijun Tian, Heather McClafferty, Owen Jeffries, Michael J Shipston. Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels.
The Journal of biological chemistry.
2010 Jul; 285(31):23954-62. doi:
10.1074/jbc.m110.137802. [PMID: 20507996] - Brenden A Hurley, Hue T Tran, Naomi J Marty, Joonho Park, Wayne A Snedden, Robert T Mullen, William C Plaxton. The dual-targeted purple acid phosphatase isozyme AtPAP26 is essential for efficient acclimation of Arabidopsis to nutritional phosphate deprivation.
Plant physiology.
2010 Jul; 153(3):1112-22. doi:
10.1104/pp.110.153270. [PMID: 20348213] - Takafumi Abo, Takeshi Nagayasu, Yoshitaka Hishikawa, Tsutomu Tagawa, Atsushi Nanashima, Takatomo Yamayoshi, Keitaro Matsumoto, Shucai An, Takehiko Koji. Expression of keratinocyte growth factor and its receptor in rat tracheal cartilage: possible involvement in wound healing of the damaged cartilage.
Acta histochemica et cytochemica.
2010 Jun; 43(3):89-98. doi:
10.1267/ahc.10006. [PMID: 20628626] - Walburgis Brenner, Silke Beitz, Elke Schneider, Frank Benzing, Ronald E Unger, Frederik C Roos, Joachim W Thüroff, Christian Hampel. Adhesion of renal carcinoma cells to endothelial cells depends on PKCmu.
BMC cancer.
2010 May; 10(?):183. doi:
10.1186/1471-2407-10-183. [PMID: 20459627] - Pai-Hsiang Su, Hsou-min Li. Stromal Hsp70 is important for protein translocation into pea and Arabidopsis chloroplasts.
The Plant cell.
2010 May; 22(5):1516-31. doi:
10.1105/tpc.109.071415. [PMID: 20484004] - Brian G Kennedy, Asad J Torabi, Rafal Kurzawa, Stephen F Echtenkamp, Nancy J Mangini. Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium.
Molecular vision.
2010 Apr; 16(?):665-75. doi:
NULL. [PMID: 20405023] - Marion David, Estelle Wannecq, Françoise Descotes, Silvia Jansen, Blandine Deux, Johnny Ribeiro, Claire-Marie Serre, Sandra Grès, Nathalie Bendriss-Vermare, Mathieu Bollen, Simone Saez, Junken Aoki, Jean-Sébastien Saulnier-Blache, Philippe Clézardin, Olivier Peyruchaud. Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts.
PloS one.
2010 Mar; 5(3):e9741. doi:
10.1371/journal.pone.0009741. [PMID: 20305819] - Laila Sbabou, Bruna Bucciarelli, Susan Miller, Junqi Liu, Fatiha Berhada, Abdelkarim Filali-Maltouf, Deborah Allan, Carroll Vance. Molecular analysis of SCARECROW genes expressed in white lupin cluster roots.
Journal of experimental botany.
2010 Mar; 61(5):1351-63. doi:
10.1093/jxb/erp400. [PMID: 20167612] - Aneta Kasza, Paulina Wyrzykowska, Irena Horwacik, Piotr Tymoszuk, Danuta Mizgalska, Karren Palmer, Hanna Rokita, Andrew D Sharrocks, Jolanta Jura. Transcription factors Elk-1 and SRF are engaged in IL1-dependent regulation of ZC3H12A expression.
BMC molecular biology.
2010 Feb; 11(?):14. doi:
10.1186/1471-2199-11-14. [PMID: 20137095] - H Jia, L Cheng, M Tickner, A Bagherzadeh, D Selwood, I Zachary. Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity.
British journal of cancer.
2010 Feb; 102(3):541-52. doi:
10.1038/sj.bjc.6605539. [PMID: 20087344] - Mo Wang, Kejian Wang, Ding Tang, Cunxu Wei, Ming Li, Yi Shen, Zhengchang Chi, Minghong Gu, Zhukuan Cheng. The central element protein ZEP1 of the synaptonemal complex regulates the number of crossovers during meiosis in rice.
The Plant cell.
2010 Feb; 22(2):417-30. doi:
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Cell and tissue research.
2010 Feb; 339(2):449-57. doi:
10.1007/s00441-009-0882-y. [PMID: 19902259] - Silvio Notari, Francisco J Moleres, Stephen B Hunter, Ermias D Belay, Lawrence B Schonberger, Ignazio Cali, Piero Parchi, Wun-Ju Shieh, Paul Brown, Sherif Zaki, Wen-Quan Zou, Pierluigi Gambetti. Multiorgan detection and characterization of protease-resistant prion protein in a case of variant CJD examined in the United States.
PloS one.
2010 Jan; 5(1):e8765. doi:
10.1371/journal.pone.0008765. [PMID: 20098730] - Guido T Bommer, Ying Feng, Ayaka Iura, Thomas J Giordano, Rork Kuick, Hüseyin Kadikoy, Deanna Sikorski, Rong Wu, Kathleen R Cho, Eric R Fearon. IRS1 regulation by Wnt/beta-catenin signaling and varied contribution of IRS1 to the neoplastic phenotype.
The Journal of biological chemistry.
2010 Jan; 285(3):1928-38. doi:
10.1074/jbc.m109.060319. [PMID: 19843521] - Yi-Feng Chen, Zhiyong Gao, Robert J Kerris, Wuyi Wang, Brad M Binder, G Eric Schaller. Ethylene receptors function as components of high-molecular-mass protein complexes in Arabidopsis.
PloS one.
2010 Jan; 5(1):e8640. doi:
10.1371/journal.pone.0008640. [PMID: 20062808] - Marcel Schouten, Cornelis van't Veer, Joris J T H Roelofs, Marcel Levi, Tom van der Poll. Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study.
Critical care (London, England).
2010; 14(4):R145. doi:
10.1186/cc9213. [PMID: 20682036] - Kristian Kiilerich, Mikkel Gudmundsson, Jesper B Birk, Carsten Lundby, Sarah Taudorf, Peter Plomgaard, Bengt Saltin, Per A Pedersen, Jorgen F P Wojtaszewski, Henriette Pilegaard. Low muscle glycogen and elevated plasma free fatty acid modify but do not prevent exercise-induced PDH activation in human skeletal muscle.
Diabetes.
2010 Jan; 59(1):26-32. doi:
10.2337/db09-1032. [PMID: 19833896] - Xin Ge, Yu Qiu, Horace H Loh, Ping-Yee Law. GRIN1 regulates micro-opioid receptor activities by tethering the receptor and G protein in the lipid raft.
The Journal of biological chemistry.
2009 Dec; 284(52):36521-36534. doi:
10.1074/jbc.m109.024109. [PMID: 19861419] - Anke Hannemann, Jenny K Christie, Peter W Flatman. Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominant-negative effect of the AF splice variant.
The Journal of biological chemistry.
2009 Dec; 284(51):35348-58. doi:
10.1074/jbc.m109.060004. [PMID: 19854835] - Morten Tryland, Christian Lydersen, Kit M Kovacs, Stein Istre Thoresen. Serum chemistry reference values in free-ranging north Atlantic male walruses (Odobenus rosmarus rosmarus) from the Svalbard archipelago.
Veterinary clinical pathology.
2009 Dec; 38(4):501-6. doi:
10.1111/j.1939-165x.2009.00154.x. [PMID: 19473331] - Lisa R Meeks, Balasubrahmanyam Addepalli, Arthur G Hunt. Characterization of genes encoding poly(A) polymerases in plants: evidence for duplication and functional specialization.
PloS one.
2009 Nov; 4(11):e8082. doi:
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Veterinary anaesthesia and analgesia.
2009 Nov; 36(6):555-61. doi:
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PLoS pathogens.
2009 Nov; 5(11):e1000666. doi:
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PloS one.
2009 Oct; 4(10):e7575. doi:
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Molecular cancer.
2009 Sep; 8(?):74. doi:
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BMC gastroenterology.
2009 Sep; 9(?):68. doi:
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The Journal of biological chemistry.
2009 Aug; 284(34):22590-600. doi:
10.1074/jbc.m109.032599. [PMID: 19564338] - Mohammad Fallahi-Sichani, Jennifer J Linderman. Lipid raft-mediated regulation of G-protein coupled receptor signaling by ligands which influence receptor dimerization: a computational study.
PloS one.
2009 Aug; 4(8):e6604. doi:
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Human genomics and proteomics : HGP.
2009 Jun; 2009(?):453634. doi:
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Journal of the National Cancer Institute.
2009 Jun; 101(11):782-92. doi:
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Retrovirology.
2009 Jun; 6(?):53. doi:
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