2,4-Hexadienal (BioDeep_00000872548)

Main id: BioDeep_00000004211

 

natural product


代谢物信息卡片


2,4-Hexadienal

化学式: C6H8O (96.0575)
中文名称: 2,4-己二烯醛
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C/C=C/C=C/C=O
InChI: InChI=1S/C6H8O/c1-2-3-4-5-6-7/h2-6H,1H3/b3-2+,5-4+

描述信息

(e,e)-2,4-hexadienal, also known as fema 3429, is a member of the class of compounds known as medium-chain aldehydes. Medium-chain aldehydes are an aldehyde with a chain length containing between 6 and 12 carbon atoms (e,e)-2,4-hexadienal is slightly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). (e,e)-2,4-hexadienal can be found in a number of food items such as fishes, tea, nuts, and fruits, which makes (e,e)-2,4-hexadienal a potential biomarker for the consumption of these food products.

同义名列表

3 个代谢物同义名

2,4-Hexadienal; 2,4-Hexadienal; 2,4-Hexadienal



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

19 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 APOB, CYP2E1, HPGDS, SPTAN1, TYR
Peripheral membrane protein 2 CYP2E1, GBA1
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 2 APOB, CYP2E1
cytosol 6 AKR1A1, AKR1B10, APOB, HPGDS, LIPE, SPTAN1
trans-Golgi network 1 GBA1
nucleoplasm 1 HPGDS
Cell membrane 1 LIPE
Synapse 1 AKR1A1
cell cortex 1 SPTAN1
cell junction 1 SPTAN1
Golgi apparatus 2 ATRN, GBA1
lysosomal membrane 2 GAA, GBA1
mitochondrial inner membrane 1 CYP2E1
neuronal cell body 1 APOB
smooth endoplasmic reticulum 1 APOB
Cytoplasm, cytosol 2 AKR1A1, LIPE
Lysosome 4 AKR1B10, GAA, GBA1, TYR
plasma membrane 5 APOB, ATRN, BCHE, GAA, SPTAN1
Membrane 3 GAA, LIPE, SPTAN1
apical plasma membrane 1 AKR1A1
caveola 1 LIPE
extracellular exosome 6 AKR1A1, APOB, ATRN, GAA, GBA1, SPTAN1
Lysosome membrane 2 GAA, GBA1
Lumenal side 1 GBA1
endoplasmic reticulum 1 GBA1
extracellular space 4 AKR1A1, APOB, ATRN, BCHE
lysosomal lumen 3 APOB, GAA, GBA1
perinuclear region of cytoplasm 1 TYR
mitochondrion 1 AKR1B10
intracellular membrane-bounded organelle 6 APOB, CYP2E1, GAA, HPGDS, SPTAN1, TYR
Microsome membrane 1 CYP2E1
Single-pass type I membrane protein 2 ATRN, TYR
Secreted 4 AKR1B10, APOB, BCHE, GAA
extracellular region 5 AKR1B10, APOB, BCHE, GAA, SPTAN1
[Isoform 2]: Secreted 1 ATRN
Extracellular vesicle 1 SPTAN1
chylomicron 1 APOB
low-density lipoprotein particle 1 APOB
very-low-density lipoprotein particle 1 APOB
actin cytoskeleton 1 SPTAN1
microtubule cytoskeleton 1 SPTAN1
Melanosome membrane 1 TYR
Early endosome 1 APOB
Golgi-associated vesicle 1 TYR
Apical cell membrane 1 AKR1A1
Mitochondrion inner membrane 1 CYP2E1
Cytoplasm, cytoskeleton 1 SPTAN1
cell projection 1 SPTAN1
Cytoplasm, cell cortex 1 SPTAN1
blood microparticle 1 BCHE
[Isoform 3]: Secreted 1 ATRN
endosome lumen 1 APOB
Lipid droplet 2 APOB, LIPE
Membrane, caveola 1 LIPE
tertiary granule membrane 1 GAA
Melanosome 1 TYR
endoplasmic reticulum lumen 2 APOB, BCHE
cortical actin cytoskeleton 1 SPTAN1
specific granule lumen 1 SPTAN1
tertiary granule lumen 1 SPTAN1
azurophil granule membrane 1 GAA
endoplasmic reticulum exit site 1 APOB
nuclear envelope lumen 1 BCHE
clathrin-coated endocytic vesicle membrane 1 APOB
spectrin 1 SPTAN1
ficolin-1-rich granule membrane 1 GAA
[Isoform 1]: Cell membrane 1 ATRN
endocytic vesicle lumen 1 APOB
chylomicron remnant 1 APOB
intermediate-density lipoprotein particle 1 APOB
mature chylomicron 1 APOB
autolysosome lumen 1 GAA
organelle 1 SPTAN1


文献列表

  • Renata Zawirska-Wojtasiak, Beata Jankowska, Paulina Piechowska, Sylwia Mildner-Szkudlarz. Vitamin C and aroma composition of fresh leaves from Kalanchoe pinnata and Kalanchoe daigremontiana. Scientific reports. 2019 12; 9(1):19786. doi: 10.1038/s41598-019-56359-1. [PMID: 31875020]
  • Francisco J Hidalgo, Rosario Zamora. 2,4-Alkadienal trapping by phenolics. Food chemistry. 2018 Oct; 263(?):89-95. doi: 10.1016/j.foodchem.2018.04.121. [PMID: 29784333]
  • Yong-Suk Kim, Dong-Hwa Shin. Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities. Journal of agricultural and food chemistry. 2004 Feb; 52(4):781-7. doi: 10.1021/jf034936d. [PMID: 14969531]
  • . NTP toxicology and carcinogensis Studies of 2,4-hexadienal (89\% trans,trans isomer, CAS No. 142-83-6; 11\% cis,trans isomer) (Gavage Studies). National Toxicology Program technical report series. 2003 Oct; ?(509):1-290. doi: . [PMID: 14999299]
  • Po C Chan, Joel Mahler, Shyamal Peddada, Liat Lomnitski, Abraham Nyska. Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice. Archives of toxicology. 2003 Sep; 77(9):511-20. doi: 10.1007/s00204-003-0481-8. [PMID: 12879212]
  • Ping C Lee, Christa Picchiottino. Short term feeding of hexadienal to postnatal rats: effects on stomach aldehyde dehydrogenase. Toxicology letters. 2003 Jan; 136(3):173-81. doi: 10.1016/s0378-4274(02)00334-x. [PMID: 12505270]
  • A Nyska, C R Moomaw, L Lomnitski, P C Chan. Glutathione S-transferase pi expression in forestomach carcinogenesis process induced by gavage-administered 2,4-hexadienal in the F344 rat. Archives of toxicology. 2001 Dec; 75(10):618-24. doi: 10.1007/s002040100278. [PMID: 11808924]
  • S Srivastava, S J Watowich, J M Petrash, S K Srivastava, A Bhatnagar. Structural and kinetic determinants of aldehyde reduction by aldose reductase. Biochemistry. 1999 Jan; 38(1):42-54. doi: 10.1021/bi981794l. [PMID: 9890881]