BQ 485 (BioDeep_00000008623)

   


代谢物信息卡片


N-(N-(N-((Hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-D-tryptophyl)-D-tryptophan

化学式: C35H44N6O5 (628.3373)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)O)NC(=O)N5CCCCCC5
InChI: InChI=1S/C35H44N6O5/c1-22(2)17-29(40-35(46)41-15-9-3-4-10-16-41)32(42)38-30(18-23-20-36-27-13-7-5-11-25(23)27)33(43)39-31(34(44)45)19-24-21-37-28-14-8-6-12-26(24)28/h5-8,11-14,20-22,29-31,36-37H,3-4,9-10,15-19H2,1-2H3,(H,38,42)(H,39,43)(H,40,46)(H,44,45)



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AXIN2, EDN1, EGFR, GJA1, NCF1, PTPN11, ROCK1
Peripheral membrane protein 2 NCF1, ROCK1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 3 EGFR, GJA1, SLC33A1
Nucleus 5 AXIN2, EGFR, GJA1, MPO, PTPN11
cytosol 5 AXIN2, GJA1, NCF1, PTPN11, ROCK1
dendrite 1 NCF1
centrosome 1 AXIN2
nucleoplasm 3 GJA1, MPO, PTPN11
Cell membrane 4 AGTR2, EGFR, GJA1, ROCK1
Cytoplasmic side 1 NCF1
lamellipodium 1 ROCK1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 3 AGTR2, GJA1, SLC33A1
Golgi apparatus membrane 1 ROCK1
cell junction 2 EGFR, GJA1
cell surface 1 EGFR
glutamatergic synapse 1 EGFR
Golgi apparatus 1 GJA1
Golgi membrane 4 EGFR, GJA1, ROCK1, SLC33A1
lysosomal membrane 1 EGF
neuronal cell body 1 NCF1
Cytoplasm, cytosol 1 NCF1
Lysosome 1 MPO
endosome 1 EGFR
plasma membrane 9 AGTR2, AXIN2, EDNRA, EGF, EGFR, GJA1, NCF1, ROCK1, SLC33A1
Membrane 5 EGF, EGFR, NCF1, ROCK1, SLC33A1
apical plasma membrane 2 EGFR, GJA1
basolateral plasma membrane 1 EGFR
extracellular exosome 2 EGF, MPO
endoplasmic reticulum 1 GJA1
extracellular space 4 EDN1, EGF, EGFR, MPO
perinuclear region of cytoplasm 1 EGFR
Schaffer collateral - CA1 synapse 1 ROCK1
gap junction 1 GJA1
intercalated disc 1 GJA1
mitochondrion 2 GJA1, PTPN11
protein-containing complex 2 EGFR, PTPN11
intracellular membrane-bounded organelle 2 GJA1, MPO
Single-pass type I membrane protein 1 EGFR
Secreted 1 EDN1
extracellular region 4 EDN1, EGF, MPO, ROCK1
cytoplasmic side of plasma membrane 1 NCF1
basal part of cell 1 EDN1
nuclear membrane 1 EGFR
beta-catenin destruction complex 1 AXIN2
Cell projection, lamellipodium 1 ROCK1
Membrane raft 2 EGFR, GJA1
Cytoplasm, cytoskeleton 1 ROCK1
focal adhesion 2 EGFR, GJA1
intracellular vesicle 1 EGFR
secretory granule 1 MPO
Cell junction, gap junction 1 GJA1
connexin complex 1 GJA1
contractile muscle fiber 1 GJA1
fascia adherens 1 GJA1
intermediate filament 1 GJA1
lateral plasma membrane 1 GJA1
Cell projection, ruffle 1 ROCK1
ruffle 1 ROCK1
receptor complex 1 EGFR
cytoskeleton 1 ROCK1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 ROCK1
centriole 1 ROCK1
Golgi-associated vesicle membrane 1 GJA1
cytoplasmic stress granule 1 ROCK1
basal plasma membrane 1 EGFR
azurophil granule 1 MPO
synaptic membrane 1 EGFR
secretory granule lumen 1 ROCK1
platelet alpha granule lumen 1 EGF
transport vesicle 1 EDN1
tight junction 1 GJA1
azurophil granule lumen 1 MPO
clathrin-coated endocytic vesicle membrane 2 EGF, EGFR
phagocytic vesicle lumen 1 MPO
cell-cell contact zone 1 GJA1
bleb 1 ROCK1
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
rough endoplasmic reticulum lumen 1 EDN1
Weibel-Palade body 1 EDN1
NADPH oxidase complex 1 NCF1
phagolysosome 1 NCF1
Cell projection, bleb 1 ROCK1


文献列表

  • H Taniai, M Suematsu, T Suzuki, S Norimizu, R Hori, Y Ishimura, Y Nimura. Endothelin B receptor-mediated protection against anoxia-reoxygenation injury in perfused rat liver: nitric oxide-dependent and -independent mechanisms. Hepatology (Baltimore, Md.). 2001 Apr; 33(4):894-901. doi: 10.1053/jhep.2001.23001. [PMID: 11283854]
  • S Doi, N Smedira, P A Murray. Pulmonary vasoregulation by endothelin in conscious dogs after left lung transplantation. Journal of applied physiology (Bethesda, Md. : 1985). 2000 Jan; 88(1):210-8. doi: 10.1152/jappl.2000.88.1.210. [PMID: 10642383]
  • H Kumagai, H Suzuki, M Ichikawa, M Nishizawa, N Oshima, T Saruta. Interaction between endothelin and nitric oxide in sympathetic nerve modulation in hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension. 1997 Mar; 20(1):35-42. doi: 10.1291/hypres.20.35. [PMID: 9101311]
  • H Ruetten, C Thiemermann. Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat. British journal of pharmacology. 1996 Oct; 119(3):479-86. doi: 10.1111/j.1476-5381.1996.tb15697.x. [PMID: 8894167]