LS-1667 (BioDeep_00000861184)

Main id: BioDeep_00000003915

 

PANOMIX_OTCML-2023


代谢物信息卡片


Trimethylamine, aqueous solutions not >50\\% trimethylamine, by mass [UN1297] [Flammable liquid]

化学式: C3H9N (59.0734954)
中文名称: 三甲胺溶液
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN(C)C
InChI: InChI=1S/C3H9N/c1-4(2)3/h1-3H3

描述信息

同义名列表

45 个代谢物同义名

Trimethylamine, aqueous solutions not >50\\% trimethylamine, by mass [UN1297] [Flammable liquid]; Trimethylamine, anhydrous [UN1083] [Flammable gas]; Trimethylamine(alkyl-substituted derivatives); Trimethylamine solution (30\\% or less); Trimethylamine, in aqueous solution; Trimethylamine-14C hydrochloride; InChI=1\C3H9N\c1-4(2)3\h1-3H; Methanamine, N,N-dimethyl-; Methylamine, N,N-dimethyl-; Trimethylamine solution; N,N-dimethylmethanamine; Dimethylmethaneamine; EINECS 200-875-0; FEMA Number 3241; N-Trimethylamine; NCIOpen2_007868; W324108_ALDRICH; W550132_ALDRICH; 243205_ALDRICH; trimethylamine; 426474_ALDRICH; Trimethylamin; FEMA No. 3241; 92260_FLUKA; 92251_FLUKA; T3035_SIGMA; 92262_FLUKA; CHEBI:18139; CCRIS 6283; 4558-12-7; (CH3)3NH+; AI3-15639; HSDB 808; (CH3)3NH; (CH3)3N; N(CH3)3; 75-50-3; LS-1667; UN1083; C00565; UN1297; C04629; c1215; NMe3; TML



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(8)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Muhammad Abrar Hasnat, Arkadiusz Zupok, Michal Gorka, Chantal Iobbi-Nivol, Aleksandra Skirycz, Cécile Jourlin-Castelli, Frank Bier, Saloni Agarwal, Ehizode Irefo, Silke Leimkühler. Iron limitation indirectly reduces the Escherichia coli torCAD operon expression by a reduction of molybdenum cofactor availability. Microbiology spectrum. 2024 Jan; ?(?):e0348023. doi: 10.1128/spectrum.03480-23. [PMID: 38193660]
  • Lei Liu, Huifang Xu, Jian Wang, Haiyan Wang, Saisai Ren, Qian Huang, Mingyan Zhang, Hui Zhou, Chunyan Yang, Lu Jia, Yu Huang, Hao Zhang, Yanling Tao, Ying Li, Yanan Min. Trimethylamine-N-oxide (TMAO) and basic fibroblast growth factor (bFGF) are possibly involved in corticosteroid resistance in adult patients with immune thrombocytopenia. Thrombosis research. 2024 Jan; 233(?):25-36. doi: 10.1016/j.thromres.2023.11.003. [PMID: 37988847]
  • Shan Huang, Si Ying Lim, Sock Hwee Tan, Mark Y Chan, Wuzhong Ni, Sam Fong Yau Li. Targeted Plasma Metabolomics Reveals Association of Acute Myocardial Infarction Risk with the Dynamic Balance between Trimethylamine-N-oxide, Betaine, and Choline. Journal of agricultural and food chemistry. 2023 Oct; ?(?):. doi: 10.1021/acs.jafc.2c08241. [PMID: 37781984]
  • Qingmiao Ma, Masafumi Noda, Narandalai Danshiitsoodol, Masanori Sugiyama. Fermented Stevia Improves Alcohol Poisoning Symptoms Associated with Changes in Mouse Gut Microbiota. Nutrients. 2023 Aug; 15(17):. doi: 10.3390/nu15173708. [PMID: 37686739]
  • Hao Cheng, Dandan Zhang, Jing Wu, Juan Liu, Yaochuan Zhou, Yuzhu Tan, Wuwen Feng, Cheng Peng. Interactions between gut microbiota and polyphenols: A mechanistic and metabolomic review. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jul; 119(?):154979. doi: 10.1016/j.phymed.2023.154979. [PMID: 37552899]
  • Hui Ye, Xuemei Liu, Haozhou Huang, Lin Huang, Yang Bao, Hongyan Ma, Junzhi Lin, Xiaoming Bao, Dingkun Zhang, Runchun Xu. An Improved Technique for Trimethylamine Detection in Animal-Derived Medicine by Headspace Gas Chromatography-Tandem Quadrupole Mass Spectrometry. Journal of visualized experiments : JoVE. 2023 03; ?(193):. doi: 10.3791/65291. [PMID: 36971441]
  • Ateequr Rehman, Susan M Tyree, Sophie Fehlbaum, Gillian DunnGalvin, Charalampos G Panagos, Bertrand Guy, Shriram Patel, Timothy G Dinan, Asim K Duttaroy, Ruedi Duss, Robert E Steinert. A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults. The Journal of nutrition. 2023 01; 153(1):96-105. doi: 10.1016/j.tjnut.2022.11.009. [PMID: 36913483]
  • Chen Yong, Guo-Shun Huang, Hong-Wei Ge, Qing-Min Sun, Kun Gao, En-Chao Zhou. [Effect of traditional Chinese medicine in attenuating chronic kidney disease and its complications by regulating gut microbiota-derived metabolite trimethylamine N-oxide: a review]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Jan; 48(2):321-328. doi: 10.19540/j.cnki.cjcmm.20220726.501. [PMID: 36725221]
  • Peng Zhou, Xiao-Ni Zhao, Yao-Yao Ma, Tong-Juan Tang, Shu-Shu Wang, Liang Wang, Jin-Ling Huang. Virtual screening analysis of natural flavonoids as trimethylamine (TMA)-lyase inhibitors for coronary heart disease. Journal of food biochemistry. 2022 12; 46(12):e14376. doi: 10.1111/jfbc.14376. [PMID: 35945702]
  • Laura Díez-Ricote, Paloma Ruiz-Valderrey, Víctor Micó, Ruth Blanco, Joao Tomé-Carneiro, Alberto Dávalos, José M Ordovás, Lidia Daimiel. TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis. International journal of molecular sciences. 2022 Oct; 23(20):. doi: 10.3390/ijms232012107. [PMID: 36292963]
  • Jing Xue, Jie Xu, Mingming Zhao, Aoming Jin, Aichun Cheng, Xue Jiang, Ke Li, Jinxi Lin, Xia Meng, Hao Li, Lemin Zheng, Yongjun Wang. Residual Risk of Trimethylamine-N-Oxide and Choline for Stroke Recurrence in Patients With Intensive Secondary Therapy. Journal of the American Heart Association. 2022 10; 11(19):e027265. doi: 10.1161/jaha.122.027265. [PMID: 36193936]
  • Nida Buawangpong, Kanokporn Pinyopornpanish, Arintaya Phrommintikul, Nathamol Chindapan, Sakamon Devahastin, Nipon Chattipakorn, Siriporn C Chattipakorn. Increased plasma trimethylamine-N-oxide levels are associated with mild cognitive impairment in high cardiovascular risk elderly population. Food & function. 2022 Oct; 13(19):10013-10022. doi: 10.1039/d2fo02021a. [PMID: 36069253]
  • Jiexin Zhang, Caiwen Ou, Minsheng Chen. Curcumin attenuates cadmium-induced atherosclerosis by regulating trimethylamine-N-oxide synthesis and macrophage polarization through remodeling the gut microbiota. Ecotoxicology and environmental safety. 2022 Oct; 244(?):114057. doi: 10.1016/j.ecoenv.2022.114057. [PMID: 36084504]
  • C M Florea, R Rosu, G Cismaru, R Moldovan, L Vlase, V Toma, N Decea, B Ancuta, G A Filip. Chronic oral trimethylamine-N-oxide administration induces experimental incipient atherosclerosis in non-genetically modified mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2022 Oct; 73(5):. doi: 10.26402/jpp.2022.5.07. [PMID: 36942810]
  • Fabian Piskol, Kerstin Neubauer, Maurice Eggers, Lisa Margarete Bode, Jan Jasper, Alan Slusarenko, Edward Reijerse, Wolfgang Lubitz, Dieter Jahn, Jürgen Moser. Two-component carnitine monooxygenase from Escherichia coli: functional characterization, inhibition and mutagenesis of the molecular interface. Bioscience reports. 2022 09; 42(9):. doi: 10.1042/bsr20221102. [PMID: 36066069]
  • Doudou Li, Ying Lu, Shuai Yuan, Xiaxia Cai, Yuan He, Jie Chen, Qiong Wu, Di He, Aiping Fang, Yacong Bo, Peige Song, Debby Bogaert, Kostas Tsilidis, Susanna C Larsson, Huanling Yu, Huilian Zhu, Evropi Theodoratou, Yimin Zhu, Xue Li. Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis. The American journal of clinical nutrition. 2022 07; 116(1):230-243. doi: 10.1093/ajcn/nqac074. [PMID: 35348578]
  • Fang Hua, Peng Zhou, Guan-Hu Bao, Tie-Jun Ling. Flavonoids in Lu'an GuaPian tea as potential inhibitors of TMA-lyase in acute myocardial infarction. Journal of food biochemistry. 2022 07; 46(7):e14110. doi: 10.1111/jfbc.14110. [PMID: 35156214]
  • Laura Bordoni, Anna M Malinowska, Irene Petracci, Artur Szwengiel, Rosita Gabbianelli, Agata Chmurzynska. Diet, Trimethylamine Metabolism, and Mitochondrial DNA: An Observational Study. Molecular nutrition & food research. 2022 07; 66(13):e2200003. doi: 10.1002/mnfr.202200003. [PMID: 35490412]
  • Mohammad Moradzad, Mohammad Abdi, Farshad Sheikh Esmaeili, Dana Ghaderi, Khaled Rahmani, Mohammad Raman Moloudi, Zakaria Vahabzadeh. Possible correlation between high circulatory levels of trimethylamine-N-oxide and 2177G>C polymorphisms of hepatic flavin containing monooxygenase 3 in Kurdish Population with non-alcoholic fatty liver disease. Molecular biology reports. 2022 Jul; 49(7):5927-5937. doi: 10.1007/s11033-022-07375-4. [PMID: 35348964]
  • Hao-Hao Shi, Li-Pin Chen, Cheng-Cheng Wang, Ying-Cai Zhao, Yu-Ming Wang, Chang-Hu Xue, Tian-Tian Zhang. Docosahexaenoic acid-acylated curcumin diester alleviates cisplatin-induced acute kidney injury by regulating the effect of gut microbiota on the lipopolysaccharide- and trimethylamine-N-oxide-mediated PI3K/Akt/NF-κB signaling pathway in mice. Food & function. 2022 Jun; 13(11):6103-6117. doi: 10.1039/d1fo04178a. [PMID: 35575345]
  • Lamuel D Bean, Jeffrey J Wing, Randall E Harris, Suzanne M Smart, Subha V Raman, M Wesley Milks. Transferrin predicts trimethylamine-N-oxide levels and is a potential biomarker of cardiovascular disease. BMC cardiovascular disorders. 2022 05; 22(1):209. doi: 10.1186/s12872-022-02644-3. [PMID: 35538408]
  • Samitinjaya Dhakal, Zahra Moazzami, Cydne Perry, Moul Dey. Effects of Lean Pork on Microbiota and Microbial-Metabolite Trimethylamine-N-Oxide: A Randomized Controlled Non-Inferiority Feeding Trial Based on the Dietary Guidelines for Americans. Molecular nutrition & food research. 2022 05; 66(9):e2101136. doi: 10.1002/mnfr.202101136. [PMID: 35182101]
  • Shuai Zhao, Manman Xu, Ruixin Liu, Yonggan Xue, Jun Nie, Yincheng Chang. NIR-II Fluorescent Probe for Detecting Trimethylamine Based on Intermolecular Charge Transfer. Chemistry (Weinheim an der Bergstrasse, Germany). 2022 Apr; 28(24):e202200113. doi: 10.1002/chem.202200113. [PMID: 35324048]
  • Yuan-Yuan Cai, Feng-Qing Huang, Xingzhen Lao, Yawen Lu, Xuejiao Gao, Raphael N Alolga, Kunpeng Yin, Xingchen Zhou, Yun Wang, Baolin Liu, Jing Shang, Lian-Wen Qi, Jing Li. Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis. NPJ biofilms and microbiomes. 2022 03; 8(1):11. doi: 10.1038/s41522-022-00273-4. [PMID: 35273169]
  • Ruey Leng Loo, Queenie Chan, Jeremy K Nicholson, Elaine Holmes. Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide. Journal of proteome research. 2022 03; 21(3):560-589. doi: 10.1021/acs.jproteome.1c00851. [PMID: 35142516]
  • Mauro Lombardo, Giovanni Aulisa, Daniele Marcon, Gianluca Rizzo. The Influence of Animal- or Plant-Based Diets on Blood and Urine Trimethylamine-N-Oxide (TMAO) Levels in Humans. Current nutrition reports. 2022 03; 11(1):56-68. doi: 10.1007/s13668-021-00387-9. [PMID: 34990005]
  • Archita Maiti, Snehasis Daschakraborty. Can Urea and Trimethylamine-N-oxide Prevent the Pressure-Induced Phase Transition of Lipid Membrane?. The journal of physical chemistry. B. 2022 02; 126(7):1426-1440. doi: 10.1021/acs.jpcb.1c08891. [PMID: 35139638]
  • Wanwen Kong, Junyi Ma, Ying Lin, Weiyu Chen. Positive Association of Plasma Trimethylamine-N-Oxide and Atherosclerosis in Patient with Acute Coronary Syndrome. Cardiovascular therapeutics. 2022; 2022(?):2484018. doi: 10.1155/2022/2484018. [PMID: 36420057]
  • Guixiu Chen, Lin He, Xiaotao Dou, Tao Liu. Association of Trimethylamine-N-Oxide Levels with Risk of Cardiovascular Disease and Mortality among Elderly Subjects: A Systematic Review and Meta-Analysis. Cardiorenal medicine. 2022; 12(2):39-54. doi: 10.1159/000520910. [PMID: 34915483]
  • Simona Alibrandi, Fabiana Nicita, Luigi Donato, Concetta Scimone, Carmela Rinaldi, Rosalia D'Angelo, Antonina Sidoti. Adaptive Modelling of Mutated FMO3 Enzyme Could Unveil Unexplored Scenarios Linking Variant Haplotypes to TMAU Phenotypes. Molecules (Basel, Switzerland). 2021 Nov; 26(22):. doi: 10.3390/molecules26227045. [PMID: 34834137]
  • Qiao Zhang, Xiaomin Guo, Cao Xie, Zhonglian Cao, Xin Wang, Li Liu, Ping Yang. Unraveling the metabolic pathway of choline-TMA-TMAO: Effects of gypenosides and implications for the therapy of TMAO related diseases. Pharmacological research. 2021 11; 173(?):105884. doi: 10.1016/j.phrs.2021.105884. [PMID: 34530121]
  • Qian Li, Tao Wu, Min Zhang, Haixia Chen, Rui Liu. Induction of the glycolysis product methylglyoxal on trimethylamine lyase synthesis in the intestinal microbiota from mice fed with choline and dietary fiber. Food & function. 2021 Oct; 12(20):9880-9893. doi: 10.1039/d1fo01481a. [PMID: 34664588]
  • Jinghui Tang, Manman Qin, Le Tang, Dan Shan, Cheng Zhang, Yifeng Zhang, Hua Wei, Liang Qiu, Jun Yu. Enterobacter aerogenes ZDY01 inhibits choline-induced atherosclerosis through CDCA-FXR-FGF15 axis. Food & function. 2021 Oct; 12(20):9932-9946. doi: 10.1039/d1fo02021h. [PMID: 34492674]
  • Priscilla Day-Walsh, Emad Shehata, Shikha Saha, George M Savva, Barbora Nemeckova, Jasmine Speranza, Lee Kellingray, Arjan Narbad, Paul A Kroon. The use of an in-vitro batch fermentation (human colon) model for investigating mechanisms of TMA production from choline, L-carnitine and related precursors by the human gut microbiota. European journal of nutrition. 2021 Oct; 60(7):3987-3999. doi: 10.1007/s00394-021-02572-6. [PMID: 33934200]
  • Charlotte Veyrat-Durebex, Isabelle Benz-de-Bretagne, Victoria Clavier, Clément Bruno, Christian R Andres, Catherine Antar, Benjamin Hennart, François Maillot, Lydie Nadal-Desbarats, Hélène Blasco. Quality consideration for the validation of urine TMA and TMAO measurement by nuclear magnetic resonance spectroscopy in Fish Odor Syndrome. Analytical biochemistry. 2021 10; 630(?):114330. doi: 10.1016/j.ab.2021.114330. [PMID: 34364856]
  • Jose L Flores-Guerrero, Adrian Post, Peter R van Dijk, Margery A Connelly, Erwin Garcia, Gerjan Navis, Stephan J L Bakker, Robin P F Dullaart. Circulating trimethylamine-N-oxide is associated with all-cause mortality in subjects with nonalcoholic fatty liver disease. Liver international : official journal of the International Association for the Study of the Liver. 2021 10; 41(10):2371-2382. doi: 10.1111/liv.14963. [PMID: 33993608]
  • Yu-Chun Chang, Yi-Hsuan Chu, Chien-Cheng Wang, Chih-Hsuan Wang, You-Lin Tain, Hung-Wei Yang. Rapid Detection of Gut Microbial Metabolite Trimethylamine N-Oxide for Chronic Kidney Disease Prevention. Biosensors. 2021 Sep; 11(9):. doi: 10.3390/bios11090339. [PMID: 34562929]
  • Mohammed E Hefni, Maria Bergström, Torbjörn Lennqvist, Cecilia Fagerström, Cornelia M Witthöft. Simultaneous quantification of trimethylamine N-oxide, trimethylamine, choline, betaine, creatinine, and propionyl-, acetyl-, and L-carnitine in clinical and food samples using HILIC-LC-MS. Analytical and bioanalytical chemistry. 2021 Sep; 413(21):5349-5360. doi: 10.1007/s00216-021-03509-y. [PMID: 34258650]
  • Takuo Emoto, Tomohiro Hayashi, Tokiko Tabata, Tomoya Yamashita, Hikaru Watanabe, Tomoya Takahashi, Yasuhiro Gotoh, Kenjiro Kami, Naofumi Yoshida, Yoshihiro Saito, Hidekazu Tanaka, Kensuke Matsumoto, Tetsuya Hayashi, Takuji Yamada, Ken-Ichi Hirata. Metagenomic analysis of gut microbiota reveals its role in trimethylamine metabolism in heart failure. International journal of cardiology. 2021 09; 338(?):138-142. doi: 10.1016/j.ijcard.2021.06.003. [PMID: 34102245]
  • Sijing Liu, Fangting He, Tianli Zheng, Siqi Wan, Jiayi Chen, Fei Yang, Xin Xu, Xiaofang Pei. Ligustrum robustum Alleviates Atherosclerosis by Decreasing Serum TMAO, Modulating Gut Microbiota, and Decreasing Bile Acid and Cholesterol Absorption in Mice. Molecular nutrition & food research. 2021 07; 65(14):e2100014. doi: 10.1002/mnfr.202100014. [PMID: 34005835]
  • Stavroula Argyridou, Melanie J Davies, Gregory J H Biddle, Dennis Bernieh, Toru Suzuki, Nathan P Dawkins, Alex V Rowlands, Kamlesh Khunti, Alice C Smith, Thomas Yates. Evaluation of an 8-Week Vegan Diet on Plasma Trimethylamine-N-Oxide and Postchallenge Glucose in Adults with Dysglycemia or Obesity. The Journal of nutrition. 2021 07; 151(7):1844-1853. doi: 10.1093/jn/nxab046. [PMID: 33784394]
  • Yang Zhou, Wei Jin, Fei Xie, Shengyong Mao, Yanfen Cheng, Weiyun Zhu. The role of Methanomassiliicoccales in trimethylamine metabolism in the rumen of dairy cows. Animal : an international journal of animal bioscience. 2021 Jul; 15(7):100259. doi: 10.1016/j.animal.2021.100259. [PMID: 34058595]
  • Danny Orabi, Lucas J Osborn, Kevin Fung, William Massey, Anthony J Horak, Federico Aucejo, Ibrahim Choucair, Beckey DeLucia, Zeneng Wang, Jan Claesen, J Mark Brown. A surgical method for continuous intraportal infusion of gut microbial metabolites in mice. JCI insight. 2021 05; 6(9):. doi: 10.1172/jci.insight.145607. [PMID: 33986195]
  • Navendu Paul, Rudra Sarkar, Sabyasachi Sarkar. Zinc protoporphyrin-trimethylamine-N-oxide complex involves cholesterol oxidation causing atherosclerosis. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2021 05; 26(2-3):367-374. doi: 10.1007/s00775-021-01861-z. [PMID: 33713182]
  • Lisard Iglesias-Carres, Lauren A Essenmacher, Kathryn C Racine, Andrew P Neilson. Development of a High-Throughput Method to Study the Inhibitory Effect of Phytochemicals on Trimethylamine Formation. Nutrients. 2021 Apr; 13(5):. doi: 10.3390/nu13051466. [PMID: 33925806]
  • Muhammad Zubair Israr, Dennis Bernieh, Andrea Salzano, Shabana Cassambai, Yoshiyuki Yazaki, Liam M Heaney, Donald J L Jones, Leong L Ng, Toru Suzuki. Association of gut-related metabolites with outcome in acute heart failure. American heart journal. 2021 04; 234(?):71-80. doi: 10.1016/j.ahj.2021.01.006. [PMID: 33454370]
  • Makiko Shimizu, Shotaro Uehara, Hiroshi Suemizu, Hiroshi Yamazaki. In vivo drug interactions of itopride and trimethylamine mediated by flavin-containing monooxygenase 3 in humanized-liver mice. Drug metabolism and pharmacokinetics. 2021 Apr; 37(?):100369. doi: 10.1016/j.dmpk.2020.11.004. [PMID: 33513464]
  • Concetta Scimone, Simona Alibrandi, Luigi Donato, Salvatore V Giofrè, Giacomo Rao, Antonina Sidoti, Rosalia D'Angelo. Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin. Journal of clinical pharmacy and therapeutics. 2021 Apr; 46(2):304-309. doi: 10.1111/jcpt.13315. [PMID: 33247860]
  • Si Chen, Ping-Ping Jiang, Danxia Yu, Gong-Cheng Liao, Shang-Ling Wu, Ai-Ping Fang, Pei-Yan Chen, Xiao-Yan Wang, Yun Luo, Jing-An Long, Rong-Huan Zhong, Zhao-Yan Liu, Chun-Lei Li, Dao-Ming Zhang, Hui-Lian Zhu. Effects of probiotic supplementation on serum trimethylamine-N-oxide level and gut microbiota composition in young males: a double-blinded randomized controlled trial. European journal of nutrition. 2021 Mar; 60(2):747-758. doi: 10.1007/s00394-020-02278-1. [PMID: 32440731]
  • Xing Heng, Wugao Liu, Weihua Chu. Identification of choline-degrading bacteria from healthy human feces and used for screening of trimethylamine (TMA)-lyase inhibitors. Microbial pathogenesis. 2021 Mar; 152(?):104658. doi: 10.1016/j.micpath.2020.104658. [PMID: 33253857]
  • Wenru Liu, Jun Mei, Jing Xie. Effect of locust bean gum-sodium alginate coatings incorporated with daphnetin emulsions on the quality of Scophthalmus maximus at refrigerated condition. International journal of biological macromolecules. 2021 Feb; 170(?):129-139. doi: 10.1016/j.ijbiomac.2020.12.089. [PMID: 33338530]
  • Shin Yoshimoto, Eri Mitsuyama, Keisuke Yoshida, Toshitaka Odamaki, Jin-Zhong Xiao. Enriched metabolites that potentially promote age-associated diseases in subjects with an elderly-type gut microbiota. Gut microbes. 2021 Jan; 13(1):1-11. doi: 10.1080/19490976.2020.1865705. [PMID: 33430687]
  • Janusz Skrzypecki, J Izdebska, A Kamińska, J Badowska, J Przybek-Skrzypecka, J Bombuy, E Samborowska, J P Szaflik. Glaucoma patients have an increased level of trimethylamine, a toxic product of gut bacteria, in the aqueous humor: a pilot study. International ophthalmology. 2021 Jan; 41(1):341-347. doi: 10.1007/s10792-020-01587-y. [PMID: 32914277]
  • Moustafa Gabr, Katarzyna Świderek. Discovery of a Histidine-Based Scaffold as an Inhibitor of Gut Microbial Choline Trimethylamine-Lyase. ChemMedChem. 2020 12; 15(23):2273-2279. doi: 10.1002/cmdc.202000571. [PMID: 32827245]
  • Signe Abitz Winther, Peter Rossing. TMAO: Trimethylamine-N-Oxide or Time to Minimize Intake of Animal Products?. The Journal of clinical endocrinology and metabolism. 2020 12; 105(12):. doi: 10.1210/clinem/dgaa428. [PMID: 32701146]
  • Makiko Shimizu, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki. Trimethylamine N-oxygenation in cynomolgus macaques genotyped for flavin-containing monooxygenase 3 (FMO3). Drug metabolism and pharmacokinetics. 2020 Dec; 35(6):571-573. doi: 10.1016/j.dmpk.2020.07.001. [PMID: 32967780]
  • Cheryl A M Anderson, Ryan Bradley. The potential of novel plant protein foods to improve dietary patterns and markers of cardiovascular health. The American journal of clinical nutrition. 2020 11; 112(5):1151-1152. doi: 10.1093/ajcn/nqaa253. [PMID: 33022696]
  • Kay Diederen, Jia V Li, Gillian E Donachie, Tim G de Meij, Dirk R de Waart, Theodorus B M Hakvoort, Angelika Kindermann, Josef Wagner, Victoria Auyeung, Anje A Te Velde, Sigrid E M Heinsbroek, Marc A Benninga, James Kinross, Alan W Walker, Wouter J de Jonge, Jurgen Seppen. Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn's disease. Scientific reports. 2020 11; 10(1):18879. doi: 10.1038/s41598-020-75306-z. [PMID: 33144591]
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