Diethofencarb (BioDeep_00000008483)

   

natural product


代谢物信息卡片


Pesticide3_Diethofencarb_C14H21NO4_Powmil

化学式: C14H21NO4 (267.1471)
中文名称: 乙霉威
谱图信息: 最多检出来源 Escherichia coli(natural_products) 66.67%

分子结构信息

SMILES: CCOC1=C(C=C(C=C1)NC(=O)OC(C)C)OCC
InChI: InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)

描述信息

同义名列表

3 个代谢物同义名

Diethofencarb; Pesticide3_Diethofencarb_C14H21NO4_Powmil; Diethofencarb



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 AHR, ARHGAP45, CYP1A1, PCTP, PPY, RREB1, TSHB, TUBB4B
Peripheral membrane protein 3 CYP1A1, CYP1B1, SDHB
Endoplasmic reticulum membrane 3 CYP1A1, CYP1A2, CYP1B1
Nucleus 3 AHR, RREB1, TUBB4B
cytosol 4 AHR, ARHGAP45, PCTP, TUBB4B
mitochondrial membrane 1 SDHB
nuclear body 1 RREB1
nucleoplasm 2 AHR, SDHB
ruffle membrane 1 ARHGAP45
Multi-pass membrane protein 2 MT-CYB, SYP
mitochondrial inner membrane 3 CYP1A1, MT-CYB, SDHB
neuromuscular junction 1 SYP
presynaptic membrane 1 SYP
synaptic vesicle 1 SYP
plasma membrane 2 ARHGAP45, SDHB
presynaptic active zone 1 SYP
synaptic vesicle membrane 1 SYP
terminal bouton 1 SYP
Membrane 4 ARHGAP45, CYP1B1, MT-CYB, SYP
extracellular exosome 3 RREB1, TUBB4B, VWF
endoplasmic reticulum 1 VWF
extracellular space 3 PPY, TSHB, VWF
perinuclear region of cytoplasm 1 SYP
Schaffer collateral - CA1 synapse 1 SYP
mitochondrion 4 CYP1A1, CYP1B1, MT-CYB, SDHB
protein-containing complex 1 AHR
intracellular membrane-bounded organelle 3 CYP1A1, CYP1A2, CYP1B1
Microsome membrane 3 CYP1A1, CYP1A2, CYP1B1
Secreted 3 PPY, TSHB, VWF
extracellular region 5 ARHGAP45, PPY, TSHB, TUBB4B, VWF
excitatory synapse 1 SYP
mitochondrial matrix 1 SDHB
transcription regulator complex 1 AHR
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 SYP
Extracellular vesicle 1 TUBB4B
Secreted, extracellular space, extracellular matrix 1 VWF
microtubule cytoskeleton 1 TUBB4B
Cell projection, ruffle membrane 1 ARHGAP45
Mitochondrion inner membrane 3 CYP1A1, MT-CYB, SDHB
Matrix side 1 SDHB
Cytoplasm, cytoskeleton 1 TUBB4B
microtubule 1 TUBB4B
extracellular matrix 1 VWF
collagen-containing extracellular matrix 1 VWF
nuclear speck 1 RREB1
neuron projection 1 SYP
chromatin 1 AHR
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
fibrillar center 1 RREB1
Endomembrane system 1 SYP
axonemal microtubule 1 TUBB4B
aryl hydrocarbon receptor complex 1 AHR
Nucleus speckle 1 RREB1
platelet alpha granule 1 VWF
secretory granule lumen 1 ARHGAP45
platelet alpha granule lumen 1 VWF
azurophil granule lumen 2 ARHGAP45, TUBB4B
respiratory chain complex II (succinate dehydrogenase) 1 SDHB
respiratory chain complex III 1 MT-CYB
Synapse, synaptosome 1 SYP
Weibel-Palade body 1 VWF
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR


文献列表

  • Xavier Benadict Joseph, Jeena N Baby, Sea-Fue Wang, Mary George. Emerging carbonate anion intercalated- ZnCr-layered double hydroxide/vanadium carbide nanocomposite: Sustainable design strategies based on disposal electrochemical sensor for diethofencarb fungicide monitoring. Chemosphere. 2023 Jun; ?(?):139099. doi: 10.1016/j.chemosphere.2023.139099. [PMID: 37270040]
  • Y H Liu, S K Yuan, X R Hu, C Q Zhang. Shift of Sensitivity in Botrytis cinerea to Benzimidazole Fungicides in Strawberry Greenhouse Ascribing to the Rising-lowering of E198A Subpopulation and its Visual, On-site Monitoring by Loop-mediated Isothermal Amplification. Scientific reports. 2019 08; 9(1):11644. doi: 10.1038/s41598-019-48264-4. [PMID: 31406191]
  • Sung-Woo Kim, A M Abd El-Aty, Jeong-Heui Choi, Young-Jun Lee, Truong T B Lieu, Hyung Suk Chung, Md Musfiqur Rahman, Ok-Ja Choi, Ho-Chul Shin, Gyu-Seek Rhee, Moon-Ik Chang, Hee Jung Kim, Jae-Han Shim. Contributing effect of various washing procedures and additives on the decline pattern of diethofencarb in crown daisy, a model of leafy vegetables. Food chemistry. 2016 Jun; 201(?):153-9. doi: 10.1016/j.foodchem.2016.01.064. [PMID: 26868560]
  • Helen E Carter, Hans J Cools, Jonathan S West, Michael W Shaw, Bart A Fraaije. Detection and molecular characterisation of Pyrenopeziza brassicae isolates resistant to methyl benzimidazole carbamates. Pest management science. 2013 Sep; 69(9):1040-8. doi: 10.1002/ps.3585. [PMID: 23760810]
  • Hirokazu Tarui, Yoshitaka Tomigahara, Masayoshi Matsui, Naohiko Isobe, Hideo Kaneko, Nobuyoshi Mikami. Metabolism of diethofencarb (isopropyl 3,4-diethoxyphenylcarbamate) in rats: identification of metabolites in urine. Journal of agricultural and food chemistry. 2004 Feb; 52(3):538-44. doi: 10.1021/jf034779i. [PMID: 14759145]
  • Takuo Fujisawa, Keiko Ichise-Shibuya, Toshiyuki Katagi, Luis O Ruzo, Yoshiyuki Takimoto. Metabolism of fungicide diethofencarb in grape (Vitis vinifera L.): definitive identification of thiolactic acid conjugated metabolites. Journal of agricultural and food chemistry. 2003 Aug; 51(18):5329-36. doi: 10.1021/jf034367+. [PMID: 12926879]
  • B De Schutter, R Aerts, L Rombouts. The influence of fungicides on the growth of Trichoderma asperellum. Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen). 2002; 67(2):291-8. doi: ". [PMID: 12701435]
  • D W Hollomon, J A Butters, H Barker, L Hall. Fungal beta-tubulin, expressed as a fusion protein, binds benzimidazole and phenylcarbamate fungicides. Antimicrobial agents and chemotherapy. 1998 Sep; 42(9):2171-3. doi: 10.1128/aac.42.9.2171. [PMID: 9736529]
  • S Hosokawa, J Nakamura, M Murakami, M Ineyama, T Watanabe, K Yoshioka, T Yamada, T Seki, Y Okuno, H Yamada. Effects of diethofencarb on thyroid function and hepatic UDP-glucuronyltransferase activity in rats. The Journal of toxicological sciences. 1992 Aug; 17(3):155-66. doi: 10.2131/jts.17.155. [PMID: 1453498]
  • K Saito, H Kaneko, K Sato, A Yoshitake, H Yamada. Age-related changes in metabolism of diethofencarb: relationship between metabolism in rat and hepatic drug-metabolizing enzyme activities. Xenobiotica; the fate of foreign compounds in biological systems. 1991 May; 21(5):575-82. doi: 10.3109/00498259109039497. [PMID: 1949890]