Gentiacaulein (BioDeep_00000007852)

human metabolite PANOMIX_OTCML-2023 blood metabolite

代谢物信息卡片

2,8-dihydroxy-1,6-dimethoxy-9H-xanthen-9-one

化学式: C15H12O6 (288.06338519999997)
中文名称: 龙胆山酮
谱图信息: 最多检出来源 Astragalus membranaceus(otcml) 24.44%

Reviewed

Last reviewed on 2024-08-14.

Cite this Page

Gentiacaulein. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/gentiacaulein (retrieved 2024-11-03) (BioDeep RN: BioDeep_00000007852). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1c(c(c2c(c1)oc1c(c2=O)c(cc(c1)OC)O)OC)O
InChI: InChI=1S/C15H12O6/c1-19-7-5-9(17)12-11(6-7)21-10-4-3-8(16)15(20-2)13(10)14(12)18/h3-6,16-17H,1-2H3

描述信息

同义名列表

4 个代谢物同义名

2,8-dihydroxy-1,6-dimethoxy-9H-xanthen-9-one; 2,8-Dihydroxy-1,6-dimethoxyxanthone; 1,7-Dihydroxy-3,8-dimethoxyxantone; Gentiacaulein

数据库引用编号

13 个数据库交叉引用编号

ChEBI: CHEBI:5313
KEGG: C10064
PubChem: 5281634
HMDB: HMDB0252694
Metlin: METLIN68106
ChEMBL: CHEMBL467590
KNApSAcK: C00002952
chemspider: 4444953
CAS: 15402-27-4
PMhub: MS000021355
PubChem: 12250
3DMET: B03506
NIKKAJI: J14.321I

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 个相关的物种来源信息

49933 - Gentiana acaulis:
38851 - Gentiana lutea: 10.1016/0305-1978(82)90006-0
1085736 - Gentiana orbicularis: 10.1016/0305-1978(82)90006-0
49940 - Gentianella campestris: 10.1016/0305-1978(82)90006-0
208027 - Gentianella serotina: 10.1016/0305-1978(82)90006-0
156522 - Gentianopsis barbata: 10.1016/0305-1978(82)90006-0
2884939 - Gentianopsis barbata var. stenocalyx: 10.1016/0305-1978(82)90006-0
49941 - Gentianopsis ciliata: 10.1016/0305-1978(82)90006-0
84894 - Gentianopsis crinita: 10.1016/0305-1978(82)90006-0
669700 - Gentianopsis detonsa: 10.1016/0305-1978(82)90006-0
50801 - Gentianopsis grandis: 10.1016/0305-1978(82)90006-0
866904 - Gentianopsis lanceolata: 10.1016/0305-1978(82)90006-0
50802 - Gentianopsis paludosa:
866906 - Gentianopsis thermalis: 10.1016/0305-1978(82)90006-0
2065894 - Gentianopsis virgata: 10.1016/0305-1978(82)90006-0
280743 - Haploclathra paniculata: 10.1016/S0031-9422(00)84543-4
9606 - Homo sapiens: -
137131 - Swertia punicea: 10.1021/NP50072A022

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Jagmohan S Negi, Pramod Singh, Geeta Joshi née Pant, Mohan S M Rawat. RP-HPLC analysis and antidiabetic activity of Swertia paniculata. Natural product communications. 2010 Jun; 5(6):907-10. doi: . [PMID: 20614821]
Ming-Fai Yeung, Clara B S Lau, Raphael C Y Chan, Yuying Zong, Chun-Tao Che. Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosa. Phytotherapy research : PTR. 2009 Jan; 23(1):123-5. doi: 10.1002/ptr.2506. [PMID: 19107824]
Aleksandra Isakovic, Teodora Jankovic, Ljubica Harhaji, Sladjana Kostic-Rajacic, Zoran Nikolic, Vlatka Vajs, Vladimir Trajkovic. Antiglioma action of xanthones from Gentiana kochiana: Mechanistic and structure-activity requirements. Bioorganic & medicinal chemistry. 2008 May; 16(10):5683-94. doi: 10.1016/j.bmc.2008.03.069. [PMID: 18406151]
Mirko Tomić, Gordana Tovilović, Biljana Butorović, Dijana Krstić, Teodora Janković, Ivana Aljancić, Nebojsa Menković. Neuropharmacological evaluation of diethylether extract and xanthones of Gentiana kochiana. Pharmacology, biochemistry, and behavior. 2005 Jul; 81(3):535-42. doi: 10.1016/j.pbb.2005.03.019. [PMID: 15932769]
Zhou Qing, Chen Jiachun, Liu Yanwen. [Study on chemical constituents from Swertia kauitchensis Franch]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2004 Dec; 27(12):908-10. doi: . [PMID: 15807240]
Huan-di Wang, Cheng-yu Tan, Yu-guang Du, Xue-fang Bai, Hai-feng Lu. [Study on the chemical constituents from the herb of Gentianopsis paludosa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2004 Nov; 29(11):1055-6. doi: . [PMID: 15656137]
Silvio Chericoni, Lara Testai, Vincenzo Calderone, Guido Flamini, Paola Nieri, Ivano Morelli, Enrica Martinotti. The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana. Planta medica. 2003 Aug; 69(8):770-2. doi: 10.1055/s-2003-42784. [PMID: 14531031]