Nagilactone C (BioDeep_00000007825)

 

Secondary id: BioDeep_00001870860

PANOMIX_OTCML-2023


代谢物信息卡片


5,10-dihydroxy-1,6-dimethyl-12-propan-2-yl-3,8,13-trioxapentacyclo[7.7.1.02,4.06,17.011,16]heptadeca-11,15-diene-7,14-dione

化学式: C19H22O7 (362.1365462)
中文名称: 柳杉内酯C
谱图信息: 最多检出来源 Astragalus membranaceus(otcml) 12.5%

Reviewed

Last reviewed on 2024-08-14.

Cite this Page

Nagilactone C. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/nagilactone_c (retrieved 2024-11-08) (BioDeep RN: BioDeep_00000007825). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C)C1=C2C(C3C4C(C(C5C(C4(C2=CC(=O)O1)C)O5)O)(C(=O)O3)C)O
InChI: InChI=1S/C19H22O7/c1-6(2)11-9-7(5-8(20)24-11)18(3)14-12(10(9)21)26-17(23)19(14,4)15(22)13-16(18)25-13/h5-6,10,12-16,21-22H,1-4H3/t10-,12-,13+,14-,15+,16+,18-,19-/m1/s1

描述信息

Nagilactone is a natural product found in Podocarpus hallii, Afrocarpus gracilior

同义名列表

2 个代谢物同义名

Nagilactone C; CID 442063



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuzhou Gui, Sheng Yao, Hong Yan, Liang Hu, Chengyin Yu, Fei Gao, Cong Xi, Huihui Li, Yang Ye, Yiping Wang. A novel small molecule liver X receptor transcriptional regulator, nagilactone B, suppresses atherosclerosis in apoE-deficient mice. Cardiovascular research. 2016 10; 112(1):502-14. doi: 10.1093/cvr/cvw183. [PMID: 27460841]
  • Ermias Mekuria Addo, Hee-Byung Chai, Ariaya Hymete, Mariamawit Yonathan Yeshak, Carla Slebodnick, David G I Kingston, L Harinantenaina Rakotondraibe. Antiproliferative Constituents of the Roots of Ethiopian Podocarpus falcatus and Structure Revision of 2α-Hydroxynagilactone F and Nagilactone I. Journal of natural products. 2015 Apr; 78(4):827-35. doi: 10.1021/np501062f. [PMID: 25807242]
  • Laura Faiella, Abeer Temraz, Nunziatina De Tommasi, Alessandra Braca. Diterpenes, ionol-derived, and flavone glycosides from Podocarpus elongatus. Phytochemistry. 2012 Apr; 76(?):172-7. doi: 10.1016/j.phytochem.2011.11.007. [PMID: 22189050]
  • Xueliang Fang, Lei Shao, Hui Zhang, Shaomeng Wang. CHMIS-C: a comprehensive herbal medicine information system for cancer. Journal of medicinal chemistry. 2005 Mar; 48(5):1481-8. doi: 10.1021/jm049838d. [PMID: 15743190]
  • Jenny Chan, Shakila N Khan, Isabelle Harvey, William Merrick, Jerry Pelletier. Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles. RNA (New York, N.Y.). 2004 Mar; 10(3):528-43. doi: 10.1261/rna.5200204. [PMID: 14970397]
  • K Shrestha, A H Banskota, S Kodata, S P Shrivastava, G Strobel, M B Gewali. An antiproliferative norditerpene dilactone, Nagilactone C, from Podocarpus neriifolius. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2001 Nov; 8(6):489-91. doi: 10.1078/s0944-7113(04)70071-9. [PMID: 11824527]
  • I Kubo, F J Hanke. A possible new role for the flavan-3-ol (-)-epicatechin in plants. Progress in clinical and biological research. 1986; 213(?):101-12. doi: ". [PMID: 3714735]
  • G B Russell, P G Fenemore, P Singh. Insect-control chemicals from plants. Nagilactone C, a toxic substance from the leaves of Podocarpus nivalis and P. hallii. Australian journal of biological sciences. 1972 Oct; 25(5):1025-9. doi: 10.1071/bi9721025. [PMID: 4663341]