Guanosine 3'-monophosphate (BioDeep_00000006084)

 

Secondary id: BioDeep_00001869282

human metabolite


代谢物信息卡片


{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid

化学式: C10H14N5O8P (363.058)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(otcml) 8.95%

分子结构信息

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc(N)[nH]c3=O)O1)O)OP(=O)(O)O)O
InChI: InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-5(17)6(3(1-16)22-9)23-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

描述信息

Guanosine 3-monophosphate, also known as 3-GMP or 3-guanylic acid, belongs to the class of organic compounds known as purine nucleosides. Purine nucleosides are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety. Guanosine 3-monophosphate has been identified in the human placenta (PMID: 32033212).

同义名列表

21 个代谢物同义名

{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid; Guanosine 3’-(dihydrogen phosphate); Guanosine 3-(dihydrogen phosphate); 3-Guanylic acid, monosodium salt; Guanosine 3-monophosphoric acid; GUANOSINE-3-monophosphoric acid; 3-Guanylic acid, disodium salt; Guanosine 3-phosphoric acid; Guanosine 3’-monophosphate; GUANOSINE-3-monophosphATE; 3-Guanosine monophosphate; Guanosine 3-monophosphate; Guanosine 3’-phosphate; Guanosine 3-phosphate; 3-Guanylic acid; 3-Guanylate; Guo-3-p; 3’-GMP; 3-GMP; GP; Guanosine 3'-phosphate



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ADA, ANXA5, APRT, APTX, GUCY1A1, ITPR3, RTCB
Peripheral membrane protein 2 ADA, ANXA5
Endoplasmic reticulum membrane 3 ITPR3, RTCB, STING1
Nucleus 5 APTX, LIG4, RTCA, RTCB, TRIM33
autophagosome 1 STING1
cytosol 8 ADA, ANXA5, APRT, GUCY1A1, GYPA, NT5E, RTCB, STING1
nucleoplasm 10 APRT, APTX, GYPA, ITPR3, LIG4, NT5E, RTCA, RTCB, STING1, TRIM33
Cell membrane 5 ADA, ADRB3, GYPA, NT5E, STING1
Multi-pass membrane protein 3 ADRB3, ITPR3, STING1
Golgi apparatus membrane 1 STING1
cell junction 1 ADA
cell surface 2 ADA, NT5E
glutamatergic synapse 1 GUCY1A1
Golgi apparatus 1 ATRN
Golgi membrane 1 STING1
neuronal cell body 1 ITPR3
sarcolemma 1 ANXA5
Lysosome 1 ADA
endosome 1 STING1
plasma membrane 8 ADA, ADRB3, ATRN, GYPA, IFNLR1, ITPR3, NT5E, STING1
Membrane 6 ADA, ANXA5, GYPA, IFNLR1, ITPR3, NT5E
brush border 1 ITPR3
extracellular exosome 4 ANXA5, APRT, ATRN, NT5E
endoplasmic reticulum 1 ITPR3
extracellular space 2 ATRN, IL2
perinuclear region of cytoplasm 1 STING1
intracellular membrane-bounded organelle 2 LIG4, RTCB
Single-pass type I membrane protein 3 ATRN, GYPA, IFNLR1
Secreted 1 IL2
extracellular region 3 ANXA5, APRT, IL2
Mitochondrion outer membrane 1 STING1
Single-pass membrane protein 1 GYPA
mitochondrial outer membrane 1 STING1
[Isoform 2]: Secreted 1 ATRN
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 1 ADA
external side of plasma membrane 3 ADA, ANXA5, NT5E
cytoplasmic vesicle 1 STING1
nucleolus 2 APTX, ITPR3
apical part of cell 1 ITPR3
Cytoplasm, perinuclear region 1 STING1
focal adhesion 1 ANXA5
GABA-ergic synapse 1 GUCY1A1
Peroxisome 1 STING1
sarcoplasmic reticulum 1 ITPR3
collagen-containing extracellular matrix 1 ANXA5
nuclear outer membrane 1 ITPR3
receptor complex 2 ADRB3, ITPR3
Zymogen granule membrane 1 ANXA5
chromatin 2 APTX, TRIM33
Cytoplasmic vesicle, autophagosome membrane 1 STING1
autophagosome membrane 1 STING1
Nucleus, nucleolus 1 APTX
chromosome, telomeric region 1 LIG4
Lipid-anchor, GPI-anchor 1 NT5E
[Isoform 3]: Secreted 1 ATRN
serine/threonine protein kinase complex 1 STING1
nuclear envelope 1 RTCB
Cytoplasmic vesicle membrane 1 STING1
Nucleus, nucleoplasm 2 APTX, RTCA
side of membrane 1 NT5E
secretory granule lumen 1 APRT
secretory granule membrane 2 ITPR3, STING1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 STING1
vesicle membrane 1 ANXA5
platelet dense tubular network membrane 1 ITPR3
[Isoform 1]: Cell membrane 1 ATRN
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
condensed chromosome 1 LIG4
guanylate cyclase complex, soluble 1 GUCY1A1
transport vesicle membrane 1 ITPR3
ankyrin-1 complex 1 GYPA
endothelial microparticle 1 ANXA5
DNA-dependent protein kinase-DNA ligase 4 complex 1 LIG4
nonhomologous end joining complex 1 LIG4
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
[Isoform 12]: Cytoplasm 1 APTX
DNA ligase IV complex 1 LIG4
interleukin-28 receptor complex 1 IFNLR1
tRNA-splicing ligase complex 1 RTCB
STING complex 1 STING1


文献列表

  • S T Hall, C J Hillier, A M Gero. Crithidia luciliae: regulation of purine nucleoside transport by extracellular purine concentrations. Experimental parasitology. 1996 Aug; 83(3):314-21. doi: 10.1006/expr.1996.0079. [PMID: 8823248]
  • C Ferrari, G Testori, A Scanni, S Frezzati, A Bertazzoni, M Romussi. Letter: Reduction of serum alkaline phosphatase and gamma-glutamyl transpeptidase activities by short-term clofibrate. The New England journal of medicine. 1976 Aug; 295(8):449. doi: 10.1056/nejm197608192950817. [PMID: 6912]