Glycodeoxycholate (BioDeep_00000606592)
Main id: BioDeep_00000001651
PANOMIX_OTCML-2023 Bile acids
代谢物信息卡片
N-(3alpha,12alpha-dihydroxy-5beta-cholan-24-oyl)glycine
化学式: C26H43NO5 (449.31410680000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C[C@@H](O)C[C@@]2([H])CC[C@]3([H])[C@@]([H])([C@]21C)C[C@H](O)[C@]1(C)[C@]([C@H](C)CCC(=O)NCC(=O)O)([H])CC[C@]13[H]
InChI: InChI=1S/C26H43NO5/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-/m1/s1
描述信息
D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts
D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
D013501 - Surface-Active Agents > D003902 - Detergents
A bile acid glycine conjugate of deoxycholic acid.
Glycodeoxycholic Acid is an endogenous metabolite.
Glycodeoxycholic Acid is an endogenous metabolite.
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:27471
- KEGG: C05464
- PubChem: 3035026
- Metlin: METLIN7000
- ChEMBL: CHEMBL258605
- LipidMAPS: LMST05030006
- MeSH: Glycodeoxycholic Acid
- KNApSAcK: C00030411
- CAS: 360-65-6
- MetaboLights: MTBLC27471
- PubChem: 7824
- 3DMET: B05041
- NIKKAJI: J14.409F
- medchemexpress: HY-125731
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 5691 Trypanosoma brucei: 10.1371/JOURNAL.PNTD.0001618
- 1827580 Streptomyces nigra: 10.3389/FMICB.2018.01587
- 5691 Trypanosoma brucei: 10.1371/JOURNAL.PNTD.0001618
- 1827580 Streptomyces nigra: 10.3389/FMICB.2018.01587
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Cuitong Wang, Bin Cheng, Wei Wei, Lanlan Gui, Wushuang Zeng, Yutong Wang, Yixuan Wang, Qi Chen, Liang Xu, Jia Miao, Ke Lan. Comparison of 1Beta- and 5Beta-hydroxylation of Deoxycholate and Glycodeoxycholate as In Vitro Index Reactions for Cytochrome P450 3A Activities.
Drug metabolism and disposition: the biological fate of chemicals.
2024 Jan; 52(2):126-134. doi:
10.1124/dmd.123.001513. [PMID: 38050044] - Achmad Fauzi, Suhendro, Marcellus Simadibrata, Abdul Azis Rani, Dondin Sajuthi, Permanawati, Rosvitha Amanda, Dadang Makmun. Role of glycodeoxycholic acid to induce acute pancreatitis in Macaca nemestrina.
Journal of medical primatology.
2022 06; 51(3):134-142. doi:
10.1111/jmp.12577. [PMID: 35306662] - Sławomira Drzymała-Czyż, Krzysztof Dziedzic, Artur Szwengiel, Patrycja Krzyżanowska-Jankowska, Jan K Nowak, Agata Nowicka, Raisa Aringazina, Sylwia Drzymała, Nataliya Kashirskaya, Jarosław Walkowiak. Serum bile acids in cystic fibrosis patients - glycodeoxycholic acid as a potential marker of liver disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2022 Jan; 54(1):111-117. doi:
10.1016/j.dld.2021.06.034. [PMID: 34305015] - Phylyne van Rijs, Vincenzo Fogliano. Roasting carob flour decreases the capacity to bind glycoconjugates of bile acids.
Food & function.
2020 Jul; 11(7):5924-5932. doi:
10.1039/d0fo01158d. [PMID: 32638775] - S Ahlin, C Cefalo, I Bondia-Pons, E Capristo, L Marini, A Gastaldelli, G Mingrone, J J Nolan. Bile acid changes after metabolic surgery are linked to improvement in insulin sensitivity.
The British journal of surgery.
2019 08; 106(9):1178-1186. doi:
10.1002/bjs.11208. [PMID: 31216062] - Brian Rago, Brendan Tierney, A David Rodrigues, Christopher L Holliman, Ragu Ramanathan. A multiplex HRMS assay for quantifying selected human plasma bile acids as candidate OATP biomarkers.
Bioanalysis.
2018 May; 10(9):645-657. doi:
10.4155/bio-2017-0274. [PMID: 29749252] - Cheng-Shi Wang, Shou-Hou Liu, Jin Peng, Chen Tang, Wei-Guo Zhu. Bile acids cycle disruption in patients with nasopharyngeal carcinoma promotes the elevation of interleukin-10 secretion.
African health sciences.
2015 Dec; 15(4):1200-3. doi:
10.4314/ahs.v15i4.19. [PMID: 26958021] - Suzy A A Comhair, Jonathan McDunn, Carole Bennett, Jade Fettig, Serpil C Erzurum, Satish C Kalhan. Metabolomic Endotype of Asthma.
Journal of immunology (Baltimore, Md. : 1950).
2015 Jul; 195(2):643-50. doi:
10.4049/jimmunol.1500736. [PMID: 26048149] - Etem Alhan, Arif Usta, Serdar Türkyılmaz, Birgül Vanizor Kural, Cengiz Erçin. Effects of glutamine alone on the acute necrotizing pancreatitis in rats.
The Journal of surgical research.
2015 Jan; 193(1):161-7. doi:
10.1016/j.jss.2014.07.029. [PMID: 25145902] - Laura James, Ke Yan, Lisa Pence, Pippa Simpson, Sudeepa Bhattacharyya, Pritmohinder Gill, Lynda Letzig, Gregory Kearns, Richard Beger. Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity.
PloS one.
2015; 10(7):e0131010. doi:
10.1371/journal.pone.0131010. [PMID: 26208104] - Benjamin L Woolbright, Mitchell R McGill, Vincent S Staggs, Robert D Winefield, Parviz Gholami, Mojtaba Olyaee, Matthew R Sharpe, Steven C Curry, William M Lee, Hartmut Jaeschke. Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients.
Toxicological sciences : an official journal of the Society of Toxicology.
2014 Dec; 142(2):436-44. doi:
10.1093/toxsci/kfu195. [PMID: 25239633] - Xingguo Cheng, Youcai Zhang, Curtis D Klaassen. Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum.
The Journal of pharmacology and experimental therapeutics.
2014 Oct; 351(1):105-13. doi:
10.1124/jpet.114.216796. [PMID: 25034404] - Quan Shang, Grace L Guo, Akira Honda, Daniel Shi, Monica Saumoy, Gerald Salen, Guorong Xu. Bile acid flux through portal but not peripheral veins inhibits CYP7A1 expression without involvement of ileal FGF19 in rabbits.
American journal of physiology. Gastrointestinal and liver physiology.
2014 Aug; 307(4):G479-86. doi:
10.1152/ajpgi.00062.2014. [PMID: 24994853] - Li-Na Yang, Jing Wen, Yi Sun, Jia-Jia Liang, Wei-Hua Zheng, Li-Li Zhang, Yu-Jie Zhou, Zhi-Li Xiong. [Metabonomic study on the anti-liver injury effect of Si-Ni-San on rats by using UPLC-MS/MS].
Yao xue xue bao = Acta pharmaceutica Sinica.
2014 Mar; 49(3):368-73. doi:
NULL. [PMID: 24961109] - David R Taylor, Jamshid Alaghband-Zadeh, Gemma F Cross, Sohail Omar, Carel W le Roux, Royce P Vincent. Urine bile acids relate to glucose control in patients with type 2 diabetes mellitus and a body mass index below 30 kg/m2.
PloS one.
2014; 9(4):e93540. doi:
10.1371/journal.pone.0093540. [PMID: 24736330] - Arif Burak Cekic, Etem Alhan, Arif Usta, Serdar Türkyılmaz, Birgül Vanizor Kural, Cengiz Erçin. Effects of clotrimazol on the acute necrotizing pancreatitis in rats.
Inflammation.
2013 Dec; 36(6):1576-83. doi:
10.1007/s10753-013-9702-3. [PMID: 23892997] - Habtom W Ressom, Jun Feng Xiao, Leepika Tuli, Rency S Varghese, Bin Zhou, Tsung-Heng Tsai, Mohammad R Nezami Ranjbar, Yi Zhao, Jinlian Wang, Cristina Di Poto, Amrita K Cheema, Mahlet G Tadesse, Radoslav Goldman, Kirti Shetty. Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis.
Analytica chimica acta.
2012 Sep; 743(?):90-100. doi:
10.1016/j.aca.2012.07.013. [PMID: 22882828] - Filipe M Coreta-Gomes, Winchil L C Vaz, Emeric Wasielewski, Carlos F G C Geraldes, Maria João Moreno. Quantification of cholesterol solubilized in bile salt micellar aqueous solutions using (13)C nuclear magnetic resonance.
Analytical biochemistry.
2012 Aug; 427(1):41-8. doi:
10.1016/j.ab.2012.04.028. [PMID: 22569559] - Elaine Studer, Xiqiao Zhou, Renping Zhao, Yun Wang, Kazuaki Takabe, Masayuki Nagahashi, William M Pandak, Paul Dent, Sarah Spiegel, Ruihua Shi, Weiren Xu, Xuyuan Liu, Pat Bohdan, Luyong Zhang, Huiping Zhou, Phillip B Hylemon. Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.
Hepatology (Baltimore, Md.).
2012 Jan; 55(1):267-76. doi:
10.1002/hep.24681. [PMID: 21932398] - Sandeep Khurana, Hema Raina, Valeria Pappas, Jean-Pierre Raufman, Thomas L Pallone. Effects of deoxycholylglycine, a conjugated secondary bile acid, on myogenic tone and agonist-induced contraction in rat resistance arteries.
PloS one.
2012; 7(2):e32006. doi:
10.1371/journal.pone.0032006. [PMID: 22359652] - Manoj Kumar, Ravinder Nagpal, Rajesh Kumar, R Hemalatha, Vinod Verma, Ashok Kumar, Chaitali Chakraborty, Birbal Singh, Francesco Marotta, Shalini Jain, Hariom Yadav. Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases.
Experimental diabetes research.
2012; 2012(?):902917. doi:
10.1155/2012/902917. [PMID: 22611376] - E Alhan, S Türkyılmaz, C Erçin, B V Kural, D Flinte. Does nuclear factor-kappa B in peripheral mononuclear cells have a prognostic role during acute necrotizing pancreatitis in rats?.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
2012; 48(1):34-9. doi:
10.1159/000334306. [PMID: 22189444] - Youcai Zhang, Iván L Csanaky, Lois D Lehman-McKeeman, Curtis D Klaassen. Loss of organic anion transporting polypeptide 1a1 increases deoxycholic acid absorption in mice by increasing intestinal permeability.
Toxicological sciences : an official journal of the Society of Toxicology.
2011 Dec; 124(2):251-60. doi:
10.1093/toxsci/kfr236. [PMID: 21914718] - Xiaoqiang Xiang, Juha Vakkilainen, Janne T Backman, Pertti J Neuvonen, Mikko Niemi. No significant effect of the SLCO1B1 polymorphism on the pharmacokinetics of ursodeoxycholic acid.
European journal of clinical pharmacology.
2011 Nov; 67(11):1159-67. doi:
10.1007/s00228-011-1070-z. [PMID: 21655991] - Andrew D Patterson, Olivier Maurhofer, Diren Beyoglu, Christian Lanz, Kristopher W Krausz, Thomas Pabst, Frank J Gonzalez, Jean-François Dufour, Jeffrey R Idle. Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling.
Cancer research.
2011 Nov; 71(21):6590-600. doi:
10.1158/0008-5472.can-11-0885. [PMID: 21900402] - S Adisakwattana, B Chanathong. Alpha-glucosidase inhibitory activity and lipid-lowering mechanisms of Moringa oleifera leaf extract.
European review for medical and pharmacological sciences.
2011 Jul; 15(7):803-8. doi:
. [PMID: 21780550] - Sathaporn Ngamukote, Kittana Mäkynen, Thavaree Thilawech, Sirichai Adisakwattana. Cholesterol-lowering activity of the major polyphenols in grape seed.
Molecules (Basel, Switzerland).
2011 Jun; 16(6):5054-61. doi:
10.3390/molecules16065054. [PMID: 21694670] - Rima Kaddurah-Daouk, Rebecca A Baillie, Hongjie Zhu, Zhao-Bang Zeng, Michelle M Wiest, Uyen Thao Nguyen, Katie Wojnoonski, Steven M Watkins, Miles Trupp, Ronald M Krauss. Enteric microbiome metabolites correlate with response to simvastatin treatment.
PloS one.
2011; 6(10):e25482. doi:
10.1371/journal.pone.0025482. [PMID: 22022402] - Jocelyn Trottier, Andrzej Białek, Patrick Caron, Robert J Straka, Piotr Milkiewicz, Olivier Barbier. Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.
PloS one.
2011; 6(7):e22094. doi:
10.1371/journal.pone.0022094. [PMID: 21760958] - Thilo Hackert, Stefan Tudor, Klaus Felix, Dmitry Dovshanskiy, Werner Hartwig, Wolfgang A Simon, Jens Werner. Effects of pantoprazole in experimental acute pancreatitis.
Life sciences.
2010 Oct; 87(17-18):551-7. doi:
10.1016/j.lfs.2010.09.008. [PMID: 20851132] - Lay-Gaik Ooi, Min-Tze Liong. Cholesterol-lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings.
International journal of molecular sciences.
2010 Jun; 11(6):2499-522. doi:
10.3390/ijms11062499. [PMID: 20640165] - Yong Zhou, Elizabeth J Dial, Rand Doyen, Lenard M Lichtenberger. Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs.
American journal of physiology. Gastrointestinal and liver physiology.
2010 May; 298(5):G722-31. doi:
10.1152/ajpgi.00387.2009. [PMID: 20203063] - Melike Karen, Osman Yuksel, Nalan Akyürek, Ebru Ofluoğlu, Kayhan Cağlar, Tevfik T Sahin, Hatice Paşaoğlu, Leyla Memiş, Nusret Akyürek, Hasan Bostanci. Probiotic agent Saccharomyces boulardii reduces the incidence of lung injury in acute necrotizing pancreatitis induced rats.
The Journal of surgical research.
2010 May; 160(1):139-44. doi:
10.1016/j.jss.2009.02.008. [PMID: 19375719] - Xinjie Zhao, Andreas Peter, Jens Fritsche, Michaela Elcnerova, Andreas Fritsche, Hans-Ulrich Häring, Erwin D Schleicher, Guowang Xu, Rainer Lehmann. Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at?.
American journal of physiology. Endocrinology and metabolism.
2009 Feb; 296(2):E384-93. doi:
10.1152/ajpendo.90748.2008. [PMID: 19066319] - Oliver Mann, Wolf-Jonas Tiefenbacher, Jussuf Kaifi, Claus Schneider, Dirk Kluth, Christian Bloechle, Emre Yekebas, Jakob R Izbicki, Tim Strate. Effect of platelet-activating factor antagonist WEB 2086 on microcirculatory disorders in acute experimental pancreatitis of graded severity.
Pancreas.
2009 Jan; 38(1):58-64. doi:
10.1097/mpa.0b013e3181841845. [PMID: 18695628] - Femke Lutgendorff, Rian M Nijmeijer, Per A Sandström, Lena M Trulsson, Karl-Eric Magnusson, Harro M Timmerman, L Paul van Minnen, Ger T Rijkers, Hein G Gooszen, Louis M A Akkermans, Johan D Söderholm. Probiotics prevent intestinal barrier dysfunction in acute pancreatitis in rats via induction of ileal mucosal glutathione biosynthesis.
PloS one.
2009; 4(2):e4512. doi:
10.1371/journal.pone.0004512. [PMID: 19223985] - Maria Vertzoni, Helen Archontaki, Christos Reppas. Determination of intralumenal individual bile acids by HPLC with charged aerosol detection.
Journal of lipid research.
2008 Dec; 49(12):2690-5. doi:
10.1194/jlr.d800039-jlr200. [PMID: 18693215] - Femke Lutgendorff, Lena M Trulsson, L Paul van Minnen, Ger T Rijkers, Harro M Timmerman, Lennart E Franzén, Hein G Gooszen, Louis M A Akkermans, Johan D Söderholm, Per A Sandström. Probiotics enhance pancreatic glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology.
2008 Nov; 295(5):G1111-21. doi:
10.1152/ajpgi.00603.2007. [PMID: 18832452] - Serdar Turkyilmaz, Etem Alhan, Cengiz Ercin, Birgul Kural Vanizor, Nese Kaklikkaya, Burhan Ates, Selim Erdogan, Serdar Topaloglu. Effects of caffeic acid phenethyl ester on pancreatitis in rats.
The Journal of surgical research.
2008 Mar; 145(1):19-24. doi:
10.1016/j.jss.2007.04.019. [PMID: 18028950] - Serdar Turkyilmaz, Etem Alhan, Cengiz Ercin, Birgul Kural Vanizor. Effects of enalaprilat on acute necrotizing pancreatitis in rats.
Inflammation.
2007 Dec; 30(6):205-12. doi:
10.1007/s10753-007-9038-y. [PMID: 17653597] - Frank Axel Wenger, Maik Kilian, Ina Heukamp, Thomas Foitzik, Christoph Andreas Jacobi, Hans Guski, Ingolf Schimke, Joachim Michael Müller. Effects of octreotide in acute hemorrhagic necrotizing pancreatitis in rats.
Journal of gastroenterology and hepatology.
2007 Nov; 22(11):1872-6. doi:
10.1111/j.1440-1746.2006.04627.x. [PMID: 17914962] - Shi-Ying Cai, Liangshi Xiong, Charles G Wray, Nazzareno Ballatori, James L Boyer. The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution.
American journal of physiology. Regulatory, integrative and comparative physiology.
2007 Sep; 293(3):R1400-9. doi:
10.1152/ajpregu.00781.2006. [PMID: 17567710] - Thilo Hackert, Dagmar Pfeil, Werner Hartwig, Stefan Fritz, Lutz Schneider, Martha-Maria Gebhard, Markus W Büchler, Jens Werner. Platelet function in acute experimental pancreatitis.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.
2007 Apr; 11(4):439-44. doi:
10.1007/s11605-007-0128-9. [PMID: 17436127] - Nuri I Kalyoncu, Etem Alhan, Cengiz Ercin, Birgul Vanizor Kural. Effects of dual inhibitor of cyclooxygenase and 5-lipoxygenase on acute necrotizing pancreatitis in rats.
Hepato-gastroenterology.
2006 Jul; 53(70):597-602. doi:
. [PMID: 16995470] - E Alhan, S Türkyilmaz, C Erçin, N Kaklikkaya, B V Kural. Effects of omega-3 fatty acids on acute necrotizing pancreatitis in rats.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
2006; 38(3):314-21. doi:
10.1159/000094019. [PMID: 16785730] - T Keck, D Jargon, A Klünsch, O Thomusch, S Richter, V Friebe, U Adam, U T Hopt. MMP-9 in serum correlates with the development of pulmonary complications in experimental acute pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2006; 6(4):316-22. doi:
10.1159/000092797. [PMID: 16636607] - E Alhan, S Türkyilmaz, C Erçin, B V Kural. Effects of lazaroid U-74389G on acute necrotizing pancreatitis in rats.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
2006; 38(2):70-5. doi:
10.1159/000092302. [PMID: 16557023] - S Mumcu, E Alhan, S Türkyilmaz, B V Kural, C Erçin, N I Kalyoncu. Effects of N-acetylcysteine on acute necrotizing pancreatitis in rats.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
2005 May; 37(3):173-8. doi:
10.1159/000085965. [PMID: 16088183] - Gerhard Dongowski, Bertram Fritzsch, Jochen Giessler, Albert Härtl, Olaf Kuhlmann, Reinhard H H Neubert. The influence of bile salts and mixed micelles on the pharmacokinetics of quinine in rabbits.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2005 May; 60(1):147-51. doi:
10.1016/j.ejpb.2005.01.003. [PMID: 15848066] - Damian J Mole, Mark A Taylor, Neil V McFerran, Thomas Diamond. The isolated perfused liver response to a 'second hit' of portal endotoxin during severe acute pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2005; 5(4-5):475-85. doi:
10.1159/000086614. [PMID: 15985775] - G Alsfasser, B Antoniu, S P Thayer, A L Warshaw, C Fernández-del Castillo. Degradation and inactivation of plasma tumor necrosis factor-alpha by pancreatic proteases in experimental acute pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2005; 5(1):37-43; discussion 43. doi:
10.1159/000084489. [PMID: 15775698] - Etem Alhan, Nuri I Kalyoncu, Cengiz Ercin, Birgul Vanizor Kural. Effects of the celecoxib on the acute necrotizing pancreatitis in rats.
Inflammation.
2004 Oct; 28(5):303-9. doi:
10.1007/s10753-004-6055-x. [PMID: 16134005] - E Alhan, N I Kalyoncu, B V Kural, C Erçin. Effects of melatonin on acute necrotizing pancreatitis in rats.
Zeitschrift fur Gastroenterologie.
2004 Sep; 42(9):967-72. doi:
10.1055/s-2004-813321. [PMID: 15455265] - Thilo Hackert, Jens Werner, Martha-Maria Gebhard, Ernst Klar. Effects of heparin in experimental models of acute pancreatitis and post-ERCP pancreatitis.
Surgery.
2004 Feb; 135(2):131-8. doi:
10.1016/j.surg.2003.08.001. [PMID: 14739847] - E Alhan, N Kaklikkaya, O Deger, C Erçin. Effects of combined nutritional therapy on acute necrotizing pancreatitis in rats in the early phase of the disease.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
2004 Jan; 36(1):33-8. doi:
10.1159/000075072. [PMID: 14730221] - Gillian T Rich, Richard M Faulks, Martin S J Wickham, Annette Fillery-Travis. Solubilization of carotenoids from carrot juice and spinach in lipid phases: II. Modeling the duodenal environment.
Lipids.
2003 Sep; 38(9):947-56. doi:
10.1007/s11745-003-1148-z. [PMID: 14584602] - Timothy Scott Wiedmann, Wei Liang, Lamya Kamel. Solubilization of drugs by physiological mixtures of bile salts.
Pharmaceutical research.
2002 Aug; 19(8):1203-8. doi:
10.1023/a:1019858428449. [PMID: 12240947] - Ugur Sağlamkaya, M R Mas, Mehmet Yaşar, Ismail Simşek, N Nüket Mas, Fikri Kocabalkan. Penetration of meropenem and cefepim into pancreatic tissue during the course of experimental acute pancreatitis.
Pancreas.
2002 Apr; 24(3):264-8. doi:
10.1097/00006676-200204000-00009. [PMID: 11893934] - L Illum, A N Fisher, I Jabbal-Gill, S S Davis. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides.
International journal of pharmaceutics.
2001 Jul; 222(1):109-19. doi:
10.1016/s0378-5173(01)00708-6. [PMID: 11404037] - H C Walters, A L Craddock, H Fusegawa, M C Willingham, P A Dawson. Expression, transport properties, and chromosomal location of organic anion transporter subtype 3.
American journal of physiology. Gastrointestinal and liver physiology.
2000 Dec; 279(6):G1188-200. doi:
10.1152/ajpgi.2000.279.6.g1188. [PMID: 11093941] - E M Muchitsch, K Varadi, L Pichler. Effects of alpha 1-acid glycoprotein on acute pancreatitis and acute lung injury in rats.
Arzneimittel-Forschung.
2000 Nov; 50(11):987-94. doi:
10.1055/s-0031-1300322. [PMID: 11148865] - E Alhan, U Küçüktülü, C Erçin, H Efe, S Al. The effects of calcium channel blocker and thyrotropin releasing hormone on acute necrotizing pancreatitis in rats.
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.
1999 Jul; 199(1):51-8. doi:
10.1007/s004330050132. [PMID: 10494674] - K Fadden, M J Hill, E Latymer, G Low, R W Owen. Steroid metabolism along the gastrointestinal tract of the cannulated pig.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).
1999 Feb; 8(1):35-40. doi:
10.1097/00008469-199902000-00005. [PMID: 10091041] - E A Trautwein, D Rieckhoff, H F Erbersdobler. Dietary inulin lowers plasma cholesterol and triacylglycerol and alters biliary bile acid profile in hamsters.
The Journal of nutrition.
1998 Nov; 128(11):1937-43. doi:
10.1093/jn/128.11.1937. [PMID: 9808646] - H M Chen, M H Shyr, S W Ueng, M F Chen. Hyperbaric oxygen therapy attenuates pancreatic microcirculatory derangement and lung edema in an acute experimental pancreatitis model in rats.
Pancreas.
1998 Jul; 17(1):44-9. doi:
10.1097/00006676-199807000-00005. [PMID: 9667519] - A L Craddock, M W Love, R W Daniel, L C Kirby, H C Walters, M H Wong, P A Dawson. Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
The American journal of physiology.
1998 01; 274(1):G157-69. doi:
10.1152/ajpgi.1998.274.1.g157. [PMID: 9458785] - J Wu, S S Peng. Comparison of hypolipidemic effect of refined konjac meal with several common dietary fibers and their mechanisms of action.
Biomedical and environmental sciences : BES.
1997 Mar; 10(1):27-37. doi:
NULL. [PMID: 9099424] - M Hu, H Wu, C Chao, L Yang, S Xiong, Z G Zhuang, Y Huang, Y Cao, Y Li. [Pre- and post-operative changes in serum levels of glycocholic acid and 3,5,3'-triiodothyronine and their clinical significance in patients with cholelithiasis].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University.
1997; 22(2):162-4. doi:
NULL. [PMID: 9868063] - G Xu, G Salen, S Shefer, G C Ness, L B Nguyen, G S Tint, T S Parker, J Roberts, A K Batta, T S Chen, Z Zhao, X Kong. Increasing hepatic cholesterol 7alpha-hydroxylase reduces plasma cholesterol concentrations in normocholesterolemic and hypercholesterolemic rabbits.
Hepatology (Baltimore, Md.).
1996 Oct; 24(4):882-7. doi:
10.1002/hep.510240421. [PMID: 8855192] - A J Hoogstraate, J Coos Verhoef, A Pijpers, L A van Leengoed, J H Verheijden, H E Junginger, H E Boddé. In vivo buccal delivery of the peptide drug buserelin with glycodeoxycholate as an absorption enhancer in pigs.
Pharmaceutical research.
1996 Aug; 13(8):1233-7. doi:
10.1023/a:1016024606221. [PMID: 8865318] - A J Hoogstraate, J C Verhoef, B Tuk, A Pijpers, L A van Leengoed, J H Verheijden, H E Junginger, H E Boddé. In-vivo buccal delivery of fluorescein isothiocyanate-dextran 4400 with glycodeoxycholate as an absorption enhancer in pigs.
Journal of pharmaceutical sciences.
1996 May; 85(5):457-60. doi:
10.1021/js950129k. [PMID: 8742934] - T Foitzik, H G Hotz, J Schmidt, E Klar, A L Warshaw, H J Buhr. Effect of microcirculatory perfusion on distribution of trypsinogen activation peptides in acute experimental pancreatitis.
Digestive diseases and sciences.
1995 Oct; 40(10):2184-8. doi:
10.1007/bf02209003. [PMID: 7587786] - K Huch, J Schmidt, W Schratt, H P Sinn, H Buhr, C Herfarth, E Klar. Hyperoncotic dextran and systemic aprotinin in necrotizing rodent pancreatitis.
Scandinavian journal of gastroenterology.
1995 Aug; 30(8):812-6. doi:
10.3109/00365529509096333. [PMID: 7481552] - D G Bassi, T Foitzik, D W Rattner, K Lewandrowski, A L Warshaw, C Fernández-del Castillo. Failure of pentoxifylline to ameliorate severe acute pancreatitis in the rat: results of a prospective, randomized, controlled study.
Critical care medicine.
1994 Dec; 22(12):1960-3. doi:
. [PMID: 7988133] - G Vanden Bossche. Use of ionic detergents for enterovirus recovery from waste water.
Microbiological research.
1994 Sep; 149(3):231-40. doi:
10.1016/s0944-5013(11)80063-7. [PMID: 7527287] - J Kopitz, C von Reitzenstein, C Mühl, M Cantz. Role of plasma membrane ganglioside sialidase of human neuroblastoma cells in growth control and differentiation.
Biochemical and biophysical research communications.
1994 Mar; 199(3):1188-93. doi:
10.1006/bbrc.1994.1356. [PMID: 8147859] - G Salvioli, E Gaetti, R Panini, R Lugli, J M Pradelli. Different resistance of mammalian red blood cells to hemolysis by bile salts.
Lipids.
1993 Nov; 28(11):999-1003. doi:
10.1007/bf02537121. [PMID: 8277831] - N Domingo, F Chanussot, D Botta, M O Reynier, C Crotte, J Hauton, H Lafont. Modulating effects of bile salt hydrophobicity on bile secretion of the major protein of the bile lipoprotein complex.
Lipids.
1993 Oct; 28(10):883-7. doi:
10.1007/bf02537495. [PMID: 8246688] - J Schmidt, K Lewandrowski, C Fernandez-del Castillo, U Mandavilli, C C Compton, A L Warshaw, D W Rattner. Histopathologic correlates of serum amylase activity in acute experimental pancreatitis.
Digestive diseases and sciences.
1992 Sep; 37(9):1426-33. doi:
10.1007/bf01296014. [PMID: 1380425] - J Schmidt, C Fernández-del Castillo, D W Rattner, K Lewandrowski, C C Compton, A L Warshaw. Trypsinogen-activation peptides in experimental rat pancreatitis: prognostic implications and histopathologic correlates.
Gastroenterology.
1992 Sep; 103(3):1009-16. doi:
10.1016/0016-5085(92)90036-x. [PMID: 1499902] - H R Schneider-Jakob, M Cantz. Lysosomal and plasma membrane ganglioside GM3 sialidases of cultured human fibroblasts. Differentiation by detergents and inhibitors.
Biological chemistry Hoppe-Seyler.
1991 Jun; 372(6):443-50. doi:
10.1515/bchm3.1991.372.1.443. [PMID: 1910582] - D W Rattner, L M Napolitano, J Corsetti, C Compton, G G Stanford, A L Warshaw, B Chernow. Hypocalcemia in experimental pancreatitis occurs independently of changes in serum nonesterified fatty acid levels.
International journal of pancreatology : official journal of the International Association of Pancreatology.
1990 Jun; 6(4):249-62. doi:
10.1007/bf02924404. [PMID: 1698894] - K Opleta, E V O'Loughlin, E A Shaffer, J Hayden, M Hollenberg, D G Gall. Effect of epidermal growth factor on growth and postnatal development of the rabbit liver.
The American journal of physiology.
1987 Nov; 253(5 Pt 1):G622-6. doi:
10.1152/ajpgi.1987.253.5.g622. [PMID: 3500648] - M Maruyama. Selective solubilization of physalaemin-type substance P binding sites from rat brain membranes by glycodeoxycholate and NaCl.
Brain research.
1986 Apr; 370(1):186-90. doi:
10.1016/0006-8993(86)91122-4. [PMID: 3011190] - C K McSherry, E H Mosbach, B I Cohen, M Une, R J Stenger, A K Singhal. Hyodeoxycholic acid: a new approach to gallstone prevention.
American journal of surgery.
1985 Jan; 149(1):126-32. doi:
10.1016/s0002-9610(85)80021-0. [PMID: 3970744] - K Linnet, J R Andersen, P Hesselfeldt. Concentrations of glycine- and taurine-conjugated bile acids in portal and systemic venous serum in man.
Scandinavian journal of gastroenterology.
1984 Jun; 19(4):575-8. doi:
10.1080/00365521.1984.12005772. [PMID: 6463582] - Y Tazawa, M Yamada, M Nakagawa, Y Konno, K Tada. Unconjugated, glycine-conjugated, taurine-conjugated bile acid nonsulfates and sulfates in urine of young infants with cholestasis.
Acta paediatrica Scandinavica.
1984 May; 73(3):392-7. doi:
10.1111/j.1651-2227.1994.tb17754.x. [PMID: 6741539] - A L Baetz, M E McLoughlin. Serum concentration of bile acids in guinea pigs as an indicator of liver damage caused by aflatoxins.
American journal of veterinary research.
1983 Oct; 44(10):1971-2. doi:
. [PMID: 6638655] - J Goto, M Saito, T Chikai, N Goto, T Nambara. Studies on steroids. CLXXXVII. Determination of serum bile acids by high-performance liquid chromatography with fluorescence labeling.
Journal of chromatography.
1983 Sep; 276(2):289-300. doi:
NULL. [PMID: 6630379] - A I Magee, D A Grant, J Hermon-Taylor, R E Offord. Specific one-stage method for assay of enterokinase activity by release of radiolabelled activation peptides from alpha-N-[3H]acetyl-trypsinogen and the effect of calcium ions on the enzyme activity.
The Biochemical journal.
1981 Jul; 197(1):239-44. doi:
10.1042/bj1970239. [PMID: 7032517] - A K Batta, S Shefer, G Salen. Thin-layer chromatographic separation of conjugates of ursodeoxycholic acid from those of litho-, chenodeoxy-, deoxy-, and cholic acids.
Journal of lipid research.
1981 May; 22(4):712-4. doi:
". [PMID: 7276746] - P J Lowe, R Coleman. Membrane fluidity and bile salt damage.
Biochimica et biophysica acta.
1981 Jan; 640(1):55-65. doi:
10.1016/0005-2736(81)90531-9. [PMID: 7213693] - D Billington, C E Evans, P P Godfrey, R Coleman. Effects of bile salts on the plasma membranes of isolated rat hepatocytes.
The Biochemical journal.
1980 May; 188(2):321-7. doi:
10.1042/bj1880321. [PMID: 7396866] - J D Lloyd-Still, L M Demers. Serum glycine-conjugated bile acids in pediatric hepatobiliary disorders.
American journal of clinical pathology.
1979 Apr; 71(4):444-51. doi:
10.1093/ajcp/71.4.444. [PMID: 443203] - L M Demers, J D Lloyd-Still. Serum bile acid levels in protracted diarrhea of infancy.
American journal of diseases of children (1960).
1978 Oct; 132(10):1001-3. doi:
10.1001/archpedi.1978.02120350065013. [PMID: 717291]