lipid X (BioDeep_00000005667)

   


代谢物信息卡片


[(3S,5S,6R)-3-hydroxy-2-(hydroxymethyl)-5-[[(3R)-3-hydroxytetradecanoyl]amino]-6-phosphonooxyoxan-4-yl] (3R)-3-hydroxytetradecanoate

化学式: C34H66NO12P (711.4322)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(plant) 8.83%

分子结构信息

SMILES: CCCCCCCCCCCC(CC(=O)NC1C(C(C(OC1OP(=O)(O)O)CO)O)OC(=O)CC(CCCCCCCCCCC)O)O
InChI: InChI=1S/C34H66NO12P/c1-3-5-7-9-11-13-15-17-19-21-26(37)23-29(39)35-31-33(32(41)28(25-36)45-34(31)47-48(42,43)44)46-30(40)24-27(38)22-20-18-16-14-12-10-8-6-4-2/h26-28,31-34,36-38,41H,3-25H2,1-2H3,(H,35,39)(H2,42,43,44)/t26-,27-,28-,31-,32-,33-,34-/m1/s1

描述信息

An N-acyl-D-glucosamine 1-phosphate where the N-acyl group is (R)-3-hydroxytetradecanoyl and carrying an additional (R)-3-hydroxytetradecanoyl group at the 3-position.

同义名列表

5 个代谢物同义名

lipid X; 2,3-bis-(3R-hydroxy-tetradecanoyl)-alphaD-glucosamine-1-phosphate; [(3S,5S,6R)-3-hydroxy-2-(hydroxymethyl)-5-[[(3R)-3-hydroxytetradecanoyl]amino]-6-phosphonooxyoxan-4-yl] (3R)-3-hydroxytetradecanoate; 2,3-Bis(β-hydoroxymyristoyl)-β-D-glucosaminyl 1-phosphate; 2,3-Bis(3-hydroxytetradecanoyl)-β-D-glucosaminyl 1-phosphate



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

208 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(208)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 BLNK, FPR1, GNAQ, ITPR3, PRKX, SERPINB2
Endosome membrane 1 CD14
Endoplasmic reticulum membrane 1 ITPR3
Nucleus 3 GNAQ, PLCZ1, PRKX
cytosol 3 BLNK, PLCZ1, PRKCQ
nucleoplasm 4 ATP2B1, ITPR3, PLCZ1, PRKX
Cell membrane 8 ATP2B1, BLNK, C5AR1, CD14, FPR1, GNAQ, ITGAM, TNF
Lipid-anchor 1 GNAQ
Multi-pass membrane protein 4 ATP2B1, C5AR1, FPR1, ITPR3
Synapse 2 ATP2B1, GNAQ
cell surface 3 F3, ITGAM, TNF
glutamatergic synapse 1 ATP2B1
Golgi apparatus 2 CD14, GNAQ
lysosomal membrane 1 GNAQ
neuronal cell body 2 ITPR3, TNF
presynaptic membrane 1 ATP2B1
plasma membrane 14 ATP2B1, BLNK, C5AR1, CD14, F2, F3, FPR1, GNAQ, IFNLR1, ITGAM, ITPR3, PRKCQ, SERPINB2, TNF
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ATP2B1, BLNK, F3, FPR1, GNAQ, IFNLR1, ITGAM, ITPR3
basolateral plasma membrane 2 ATP2B1, C5AR1
brush border 1 ITPR3
extracellular exosome 5 ATP2B1, CD14, F2, GNAQ, ITGAM
endoplasmic reticulum 1 ITPR3
extracellular space 8 CD14, CXCL2, CXCL8, F2, F3, ITGAM, SERPINB2, TNF
perinuclear region of cytoplasm 1 PLCZ1
intracellular membrane-bounded organelle 2 ATP2B1, BLNK
pronucleus 1 PLCZ1
Single-pass type I membrane protein 3 F3, IFNLR1, ITGAM
Secreted 4 AOAH, CD14, CXCL8, F2
extracellular region 7 AOAH, CD14, CXCL2, CXCL8, F2, SERPINB2, TNF
[Isoform 1]: Membrane 1 F3
[Isoform 2]: Secreted 1 F3
centriolar satellite 1 PRKCQ
photoreceptor outer segment 1 GNAQ
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Nucleus membrane 1 GNAQ
nuclear membrane 1 GNAQ
external side of plasma membrane 4 CD14, F3, ITGAM, TNF
cytoplasmic vesicle 2 AOAH, C5AR1
nucleolus 2 ITPR3, PLCZ1
apical part of cell 2 C5AR1, ITPR3
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 1 PLCZ1
Membrane raft 3 CD14, ITGAM, TNF
sarcoplasmic reticulum 1 ITPR3
collagen-containing extracellular matrix 2 F2, F3
lateral plasma membrane 1 ATP2B1
nuclear outer membrane 1 ITPR3
receptor complex 1 ITPR3
cell projection 1 ATP2B1
phagocytic cup 1 TNF
blood microparticle 1 F2
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 CD14
Cornified envelope 1 SERPINB2
heterotrimeric G-protein complex 1 GNAQ
specific granule membrane 1 ITGAM
tertiary granule membrane 1 ITGAM
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 CD14
lipopolysaccharide receptor complex 1 CD14
plasma membrane raft 1 ITGAM
secretory granule membrane 4 C5AR1, CD14, FPR1, ITPR3
Golgi lumen 1 F2
endoplasmic reticulum lumen 1 F2
azurophil granule membrane 1 FPR1
immunological synapse 2 ATP2B1, PRKCQ
aggresome 1 PRKCQ
platelet dense tubular network membrane 1 ITPR3
ficolin-1-rich granule membrane 1 FPR1
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
integrin complex 1 ITGAM
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
transport vesicle membrane 1 ITPR3
sperm head 1 PLCZ1
integrin alphaM-beta2 complex 1 ITGAM
serine-type peptidase complex 1 F3
photoreceptor ribbon synapse 1 ATP2B1
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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  • Chiaki Okada, Hiroko Wakabayashi, Momoko Kobayashi, Akira Shinoda, Isao Tanaka, Min Yao. Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa. Scientific reports. 2016 09; 6(?):32822. doi: 10.1038/srep32822. [PMID: 27609419]
  • Jae Cho, Chul-Jin Lee, Jinshi Zhao, Hayley E Young, Pei Zhou. Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis. Nature microbiology. 2016 Aug; 1(11):16154. doi: 10.1038/nmicrobiol.2016.154. [PMID: 27780190]
  • Hayley E Young, Jinshi Zhao, Jeffrey R Barker, Ziqiang Guan, Raphael H Valdivia, Pei Zhou. Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis. mBio. 2016 Mar; 7(2):e00090. doi: 10.1128/mbio.00090-16. [PMID: 27006461]
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