Presqualene diphosphate (BioDeep_00000005204)
human metabolite Endogenous
代谢物信息卡片
化学式: C30H52O7P2 (586.3188102)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(natural_products) 0.3%
分子结构信息
SMILES: CC(=CCC/C(=C/CC/C(=C/[C@H]1[C@H](COP(=O)(O)OP(=O)(O)O)[C@@]1(C)CC/C=C(\C)/CCC=C(C)C)/C)/C)C
InChI: InChI=1S/C30H52O7P2/c1-23(2)13-9-15-25(5)17-11-18-27(7)21-28-29(22-36-39(34,35)37-38(31,32)33)30(28,8)20-12-19-26(6)16-10-14-24(3)4/h13-14,17,19,21,28-29H,9-12,15-16,18,20,22H2,1-8H3,(H,34,35)(H2,31,32,33)/b25-17+,26-19+,27-21+/t28-,29-,30-/m0/s1
描述信息
Presqualene diphosphate is an intermediate in the biosynthesis of Terpenoid. It is a substrate for Farnesyl-diphosphate farnesyltransferase. [HMDB]. Presqualene diphosphate is found in many foods, some of which are soft-necked garlic, pomes, roman camomile, and white cabbage.
Presqualene diphosphate is an intermediate in the biosynthesis of Terpenoid. It is a substrate for Farnesyl-diphosphate farnesyltransferase.
同义名列表
10 个代谢物同义名
[({[(1S,2S,3S)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid; (1alpha,2beta(e),3beta(1E,5E))-Diphosphoric acid mono((2-(4,8-dimethyl-3,7-nonadienyl)-2-methyl-3-(2,6,10-trimethyl-1,5,9-undecatrienyl)cyclopropyl)methyl) ester; {(1r,2r,3r)-2-[(3e)-4,8-Dimethylnona-3,7-Dien-1-Yl]-2-Methyl-3-[(1e,5e)-2,6,10-Trimethylundeca-1,5,9-Trien-1-Yl]cyclopropyl}methyl Trihydrogen Diphosphate; [(1R,2R,3R)-2-[(e)-4,8-Dimethylnona-3,7-dienyl]-2-methyl-3-[(2E,6E)-2,6,10-trimethylundeca-1,5,9-trienyl]cyclopropan-1-yl]methyl diphosphoric acid; [(1S,2S,3S)-2-[(e)-4,8-Dimethylnona-3,7-dienyl]-2-methyl-3-[(2E,6E)-2,6,10-trimethylundeca-1,5,9-trienyl]cyclopropan-1-yl]methyl diphosphoric acid; [(1R,2R,3R)-2-[(e)-4,8-Dimethylnona-3,7-dienyl]-2-methyl-3-[(2E,6E)-2,6,10-trimethylundeca-1,5,9-trienyl]cyclopropan-1-yl]methyl diphosphate; [(1S,2S,3S)-2-[(e)-4,8-Dimethylnona-3,7-dienyl]-2-methyl-3-[(2E,6E)-2,6,10-trimethylundeca-1,5,9-trienyl]cyclopropan-1-yl]methyl diphosphate; Presqualene diphosphoric acid; Presqualene pyrophosphate; Presqualene diphosphate
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:15442
- KEGG: C03428
- PubChem: 5280592
- PubChem: 6449797
- PubChem: 468
- HMDB: HMDB0001278
- Metlin: METLIN6132
- ChEMBL: CHEMBL1213010
- MetaCyc: CPD-465
- foodb: FDB022531
- chemspider: 4444207
- CAS: 29849-75-0
- PMhub: MS000017934
- PubChem: 6255
- LipidMAPS: LMPR0106010003
- PDB-CCD: PS7
- 3DMET: B01658
- NIKKAJI: J816.761C
- RefMet: Presqualene diphosphate
分类词条
相关代谢途径
PlantCyc(0)
代谢反应
609 个相关的代谢反应过程信息。
Reactome(68)
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- Metabolism of lipids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism of steroids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Metabolism of lipids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
7-dehydroCHOL + H+ + TPNH ⟶ CHOL + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Metabolism of lipids:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Metabolism of steroids:
H+ + TPNH + estrone ⟶ EST17b + TPN
- Cholesterol biosynthesis:
H+ + LAN + Oxygen + TPNH ⟶ 4,4DMCHtOL + H2O + HCOOH + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of lipids:
3-oxopristanoyl-CoA + CoA-SH ⟶ 4,8,12-trimethyltridecanoyl-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
ATP + MVA5PP ⟶ ADP + IPPP + Pi + carbon dioxide
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- Metabolism of lipids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism of steroids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
CAR + propionyl CoA ⟶ CoA-SH + Propionylcarnitine
- Metabolism of lipids:
CAR + propionyl CoA ⟶ CoA-SH + Propionylcarnitine
- Metabolism of steroids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Metabolism of lipids:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Metabolism of steroids:
17aHPROG + H+ + Oxygen + TPNH ⟶ 11-deoxycortisol + H2O + TPN
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Metabolism:
GAA + SAM ⟶ CRET + H+ + SAH
- Metabolism of lipids:
ACA + H+ + NADH ⟶ NAD + bHBA
- Metabolism of steroids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
- Cholesterol biosynthesis:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN
BioCyc(2)
- superpathway of sterol biosynthesis:
4-methyl-2-oxopentanoate + NAD+ + coenzyme A ⟶ CO2 + NADH + isovaleryl-CoA
- ergosterol biosynthesis:
H+ + NADPH + O2 + lanosterol ⟶ 4,4-dimethyl-5-α-cholesta-8,14,24-trien-3-β-ol + H2O + NADP+ + formate
WikiPathways(2)
- Cholesterol metabolism with Bloch and Kandutsch-Russell pathways:
7-dehydodesmosterol ⟶ 7-dehdrocholesterol
- Ergosterol biosynthesis:
PreSqualene-PP ⟶ Squalene
Plant Reactome(532)
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
DMAPP + genistein ⟶ PPi + lupiwighteone
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
PALM-CoA + Ser ⟶ 3-ketosphinganine + CoA-SH + carbon dioxide
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Secondary metabolism:
DMAPP + genistein ⟶ PPi + lupiwighteone
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
PALM-CoA + Ser ⟶ 3-ketosphinganine + CoA-SH + carbon dioxide
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
5-dehydro episterol + TPNH ⟶ 24-methylenecholesterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Secondary metabolism:
DMAPP + genistein ⟶ PPi + lupiwighteone
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
PALM-CoA + Ser ⟶ 3-ketosphinganine + CoA-SH + carbon dioxide
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Secondary metabolism:
DMAPP + genistein ⟶ PPi + lupiwighteone
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
L-Phe ⟶ ammonia + trans-cinnamate
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate
- Secondary metabolism:
Fru(6)P + L-Gln ⟶ GlcN6P + L-Glu
- Sterol biosynthesis:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA
- Secondary metabolism:
GPP + H2O ⟶ PPi + geraniol
- Sterol biosynthesis:
delta24-25-sitosterol ⟶ sitosterol
- Fatty acid and lipid metabolism:
NAD(P)H + Oxygen + lathosterol ⟶ H2O + NAD(P)+ + Provitamin D3
- Cholesterol biosynthesis I:
NAD(P)H + Oxygen + lathosterol ⟶ H2O + NAD(P)+ + Provitamin D3
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + Oxygen + lathosterol ⟶ H2O + NAD(P)+ + Provitamin D3
- Cholesterol biosynthesis III (via desmosterol):
DESMO + TPNH ⟶ CHOL + TPN
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
H+ + Oxygen + TPNH + obtusifoliol ⟶ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + H2O + HCOOH + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide
- Secondary metabolism:
ATP + CoA-SH + ferulate ⟶ AMP + PPi + feruloyl-CoA
- Sterol biosynthesis:
4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + TPNH ⟶ 4alpha-methylfecosterol + TPN
- Fatty acid and lipid metabolism:
ATP + CoA-SH + fatty acid ⟶ AMP + FACoA + PPi
- Cholesterol biosynthesis I:
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
- Cholesterol biosynthesis III (via desmosterol):
NAD(P)H + PSDP ⟶ NAD(P)+ + PPi + SQNE
INOH(2)
- Steroids metabolism ( Steroids metabolism ):
7-Dehydro-cholesterol + NADP+ ⟶ Cholesterol + NADPH
- 2 Farnesyl diphosphate + NADPH => NADP+ + Squalene + 2 Pyrophosphate ( Steroids metabolism ):
NADPH + Presqualene diphosphate ⟶ NADP+ + Pyrophosphate + Squalene
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(3)
- Sesquiterpenoid Biosynthesis:
Hydrogen Ion + NADPH + Presqualene diphosphate ⟶ NADP + Pyrophosphate + Squalene
- Triterpenoid Biosynthesis:
Hydrogen Ion + NADPH + Presqualene diphosphate ⟶ NADP + Pyrophosphate + Squalene
- Steroid Biosynthesis:
Hydrogen Ion + Lathosterol + Oxygen + ferrocytochrome b5 ⟶ 7-Dehydrocholesterol + Water + ferricytochrome b5
PharmGKB(0)
3 个相关的物种来源信息
- 9606 Homo sapiens: 10.1007/S11306-016-1051-4
- 9606 Homo sapiens: 10.1007/S11306-016-1051-4
- 9606 Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Troy Carlo, Nicos A Petasis, Bruce D Levy. Activation of polyisoprenyl diphosphate phosphatase 1 remodels cellular presqualene diphosphate.
Biochemistry.
2009 Apr; 48(13):2997-3004. doi:
10.1021/bi8020636
. [PMID: 19220020] - Sarah A Scott, Paige E Selvy, Jason R Buck, Hyekyung P Cho, Tracy L Criswell, Ashley L Thomas, Michelle D Armstrong, Carlos L Arteaga, Craig W Lindsley, H Alex Brown. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.
Nature chemical biology.
2009 Feb; 5(2):108-17. doi:
10.1038/nchembio.140
. [PMID: 19136975] - Troy Carlo, Bruce D Levy. Chemical mediators and the resolution of airway inflammation.
Allergology international : official journal of the Japanese Society of Allergology.
2008 Dec; 57(4):299-305. doi:
10.2332/allergolint.08-rai-0018
. [PMID: 18946231] - Spyros Theofilopoulos, Athanasios Lykidis, George Leondaritis, Dimitra Mangoura. Novel function of the human presqualene diphosphate phosphatase as a type II phosphatidate phosphatase in phosphatidylcholine and triacylglyceride biosynthesis pathways.
Biochimica et biophysica acta.
2008 Nov; 1781(11-12):731-42. doi:
10.1016/j.bbalip.2008.09.001
. [PMID: 18930839] - B D Levy, C N Serhan. Polyisoprenyl phosphate signaling: topography in human neutrophils.
Biochemical and biophysical research communications.
2000 Sep; 275(3):739-45. doi:
10.1006/bbrc.2000.3371
. [PMID: 10973792] - B D Levy, V V Fokin, J M Clark, M J Wakelam, N A Petasis, C N Serhan. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
1999 May; 13(8):903-11. doi:
10.1096/fasebj.13.8.903
. [PMID: 10224233] - B D Levy, N A Petasis, C N Serhan. Polyisoprenyl phosphates in intracellular signalling.
Nature.
1997 Oct; 389(6654):985-90. doi:
10.1038/40180
. [PMID: 9353124] - . .
.
. doi:
. [PMID: 16464866]