phenolphthalein (BioDeep_00000412902)

   

natural product


代谢物信息卡片


phenolphthalein

化学式: C20H14O4 (318.0892)
中文名称: 酚酞
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)OC2(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O
InChI: InChI=1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H

描述信息

A - Alimentary tract and metabolism > A06 - Drugs for constipation > A06A - Drugs for constipation > A06AB - Contact laxatives
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D010635 - Phenolphthaleins
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3720; ORIGINAL_PRECURSOR_SCAN_NO 3717
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3689; ORIGINAL_PRECURSOR_SCAN_NO 3687
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3685; ORIGINAL_PRECURSOR_SCAN_NO 3683
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3891; ORIGINAL_PRECURSOR_SCAN_NO 3888
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3687; ORIGINAL_PRECURSOR_SCAN_NO 3684
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3922; ORIGINAL_PRECURSOR_SCAN_NO 3920
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8029; ORIGINAL_PRECURSOR_SCAN_NO 8028
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8044; ORIGINAL_PRECURSOR_SCAN_NO 8041
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8074; ORIGINAL_PRECURSOR_SCAN_NO 8072
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8093; ORIGINAL_PRECURSOR_SCAN_NO 8092
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8106; ORIGINAL_PRECURSOR_SCAN_NO 8104
CONFIDENCE standard compound; INTERNAL_ID 173; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8082; ORIGINAL_PRECURSOR_SCAN_NO 8078

同义名列表

2 个代谢物同义名

phenolphthalein; Phenolphthalein



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 AKR1C3, AKR1C4, ALB, CYP1A1, ITPR3, MTF1, PHB1, TYMS
Peripheral membrane protein 1 CYP1A1
Endoplasmic reticulum membrane 4 CYP1A1, DHRS9, HSP90B1, ITPR3
Nucleus 6 AKR1C3, ALB, HSP90B1, MTF1, PHB1, TYMS
cytosol 9 AKR1C1, AKR1C2, AKR1C3, AKR1C4, ALB, HSP90B1, MTF1, SST, TYMS
centrosome 1 ALB
nucleoplasm 3 ITPR3, MTF1, PHB1
Cell membrane 2 MAG, PHB1
Multi-pass membrane protein 1 ITPR3
Synapse 1 TAC1
cell surface 1 PHB1
Golgi apparatus 1 ALB
Golgi membrane 1 INS
mitochondrial inner membrane 3 CYP1A1, PHB1, TYMS
neuronal cell body 3 ITPR3, SST, TAC1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 3 AKR1C1, AKR1C2, AKR1C4
plasma membrane 3 ITPR3, MAG, PHB1
Membrane 4 HSP90B1, ITPR3, MAG, PHB1
axon 1 TAC1
brush border 1 ITPR3
extracellular exosome 6 AKR1C1, AKR1C3, AKR1C4, ALB, HSP90B1, PHB1
endoplasmic reticulum 3 ALB, HSP90B1, ITPR3
extracellular space 5 ALB, GAST, INS, SST, TAC1
perinuclear region of cytoplasm 1 HSP90B1
mitochondrion 3 CYP1A1, PHB1, TYMS
protein-containing complex 2 ALB, HSP90B1
intracellular membrane-bounded organelle 2 CYP1A1, DHRS9
Microsome membrane 2 CYP1A1, DHRS9
Single-pass type I membrane protein 1 MAG
Secreted 4 ALB, GAST, INS, SST
extracellular region 7 ALB, GAST, HSP90B1, INS, MLN, SST, TAC1
Single-pass membrane protein 2 MAG, MLN
Mitochondrion matrix 1 TYMS
mitochondrial matrix 1 TYMS
anchoring junction 1 ALB
nucleolus 1 ITPR3
midbody 1 HSP90B1
Early endosome 1 PHB1
apical part of cell 1 ITPR3
Mitochondrion inner membrane 3 CYP1A1, PHB1, TYMS
Membrane raft 1 MAG
focal adhesion 1 HSP90B1
GABA-ergic synapse 1 SST
sarcoplasmic reticulum 1 ITPR3
collagen-containing extracellular matrix 1 HSP90B1
nuclear outer membrane 1 ITPR3
receptor complex 1 ITPR3
ciliary basal body 1 ALB
chromatin 1 MTF1
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
endosome lumen 1 INS
Melanosome 1 HSP90B1
myelin sheath 1 MAG
sperm plasma membrane 1 HSP90B1
secretory granule lumen 1 INS
secretory granule membrane 1 ITPR3
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, HSP90B1, INS
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
paranode region of axon 1 MAG
Schmidt-Lanterman incisure 1 MAG
Sarcoplasmic reticulum membrane 1 MLN
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
neuronal dense core vesicle 1 SST
Sarcoplasmic reticulum lumen 1 HSP90B1
platelet dense tubular network membrane 1 ITPR3
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
endocytic vesicle lumen 1 HSP90B1
transport vesicle membrane 1 ITPR3
compact myelin 1 MAG
endoplasmic reticulum chaperone complex 1 HSP90B1
myelin sheath adaxonal region 1 MAG
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
mesaxon 1 MAG
mitochondrial prohibitin complex 1 PHB1
ciliary transition fiber 1 ALB


文献列表

  • Michael Gold, Sonya Abdulla, Anneke Andriessen, Vivian Bucay, Ariel Haus, Qin Xiaolei, Todd Schlesinger, Weimin Song, Hua Zhong. INDIVIDUAL ARTICLE: Real-World Patient Cases Using Botanical Serum-Containing Corrective Gel as an Adjunct to Aesthetic Facial Laser or Microneedling Radiofrequency (MRF) Treatment. Journal of drugs in dermatology : JDD. 2024 Mar; 23(3):SF400676s3-SF400676s14. doi: 10.36849/jdd.sf400676. [PMID: 38443134]
  • Aleksey S Antipov, Julia G Kokunko, Svetlana A Krasnova, Victor A Utkin. Dynamic Smoothing, Filtering and Differentiation of Signals Defining the Path of the UAV. Sensors (Basel, Switzerland). 2022 Dec; 22(23):. doi: 10.3390/s22239472. [PMID: 36502174]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Sungwook Hong, Chaewon Kim, Soyoung Jeon, Eunhye Lee. Preparation of Artificial Blood from the Extract of Legume Root Nodules, and the Creation of Artificial Latent Fingermarks in Blood Using Artificial Blood. Journal of forensic sciences. 2018 Jan; 63(1):234-238. doi: 10.1111/1556-4029.13488. [PMID: 28271501]
  • Susanna Every-Palmer, Giles Newton-Howes, Mike J Clarke. Pharmacological treatment for antipsychotic-related constipation. The Cochrane database of systematic reviews. 2017 01; 1(?):CD011128. doi: 10.1002/14651858.cd011128.pub2. [PMID: 28116777]
  • Hiroshi Matsumoto, Fumiyo Saito, Masahiro Takeyoshi. Investigation of the early-response genes in chemical-induced renal carcinogenicity for the prediction of chemical carcinogenicity in rats. The Journal of toxicological sciences. 2017; 42(2):175-181. doi: 10.2131/jts.42.175. [PMID: 28321044]
  • Phyllis Wilson, Claude Masse. Detection of Synthetic Drugs as Adulterants in Natural and Herbal Slimming Products by LC-ESI-MS/MS with Polarity Switching. Journal of AOAC International. 2016 Jul; 99(4):929-940. doi: 10.5740/jaoacint.15-0295. [PMID: 27143234]
  • Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. Toxicological sciences : an official journal of the Society of Toxicology. 2015 Feb; 143(2):333-48. doi: 10.1093/toxsci/kfu231. [PMID: 25349334]
  • Daniel Petersen, Frank Kovacs. Phenolphthalein false-positive reactions from legume root nodules. Journal of forensic sciences. 2014 Mar; 59(2):481-4. doi: 10.1111/1556-4029.12352. [PMID: 24313711]
  • Satoshi Endo, Toshiyuki Matsunaga, Atsuko Matsumoto, Yuki Arai, Satoshi Ohno, Ossama El-Kabbani, Kazuo Tajima, Yasuo Bunai, Shigeru Yamano, Akira Hara, Yukio Kitade. Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D₂, and other endogenous and xenobiotic carbonyl compounds. Biochemical pharmacology. 2013 Nov; 86(9):1366-75. doi: 10.1016/j.bcp.2013.08.024. [PMID: 23994167]
  • H Wang, Y Wu, Y Zhao, W Sun, L Ding, B Guo, B Chen. Rapid screening of illicit additives in weight loss dietary supplements with desorption corona beam ionisation (DCBI) mass spectrometry. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2012 Aug; 29(8):1194-201. doi: 10.1080/19440049.2012.692395. [PMID: 22784191]
  • Zhong-Bao Yang, Dejene Eticha, Alfonso Albacete, Idupulapati Madhusudana Rao, Thomas Roitsch, Walter Johannes Horst. Physiological and molecular analysis of the interaction between aluminium toxicity and drought stress in common bean (Phaseolus vulgaris). Journal of experimental botany. 2012 May; 63(8):3109-25. doi: 10.1093/jxb/ers038. [PMID: 22371077]
  • . Toxicology study of senna (CAS No. 8013-11-4) in C57BL/6NTAC Mice and toxicology and carcinogenesis study of senna in genetically modified C3B6.129F1/Tac-Trp53tm1Brd haploinsufficient mice (Feed Studies). National Toxicology Program genetically modified model report. 2012 Apr; ?(15):1-114. doi: . [PMID: 23001288]
  • Pui Kin Lam, K S Leung, T W Wong, H H C Lee, M H Y Tang, T W L Mak. Serotonin syndrome following overdose of a non-prescription slimming product containing sibutramine: a case report. Human & experimental toxicology. 2012 Apr; 31(4):414-7. doi: 10.1177/0960327111431704. [PMID: 22249388]
  • Andrew G Netting, Julian C Theobald, Ian C Dodd. Xylem sap collection and extraction methodologies to determine in vivo concentrations of ABA and its bound forms by gas chromatography-mass spectrometry (GC-MS). Plant methods. 2012 Mar; 8(?):11. doi: 10.1186/1746-4811-8-11. [PMID: 22439865]
  • Eric G Mworia, Takashi Yoshikawa, Nadiah Salikon, Chisato Oda, William O Asiche, Naoki Yokotani, Daigo Abe, Koichiro Ushijima, Ryohei Nakano, Yasutaka Kubo. Low-temperature-modulated fruit ripening is independent of ethylene in 'Sanuki Gold' kiwifruit. Journal of experimental botany. 2012 Jan; 63(2):963-71. doi: 10.1093/jxb/err324. [PMID: 22058408]
  • Pilar Galindo, Isabel Rodriguez-Gómez, Susana González-Manzano, Montserrat Dueñas, Rosario Jiménez, Carmen Menéndez, Félix Vargas, Juan Tamargo, Celestino Santos-Buelga, Francisco Pérez-Vizcaíno, Juan Duarte. Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. PloS one. 2012; 7(3):e32673. doi: 10.1371/journal.pone.0032673. [PMID: 22427863]
  • Nikos Tzortzakis, Sofia Gouma, Eleni Dagianta, Christos Saridakis, Maria Papamichalaki, Dimitrios Goumas, Thrassyvoulos Manios. Use of fertigation and municipal solid waste compost for greenhouse pepper cultivation. TheScientificWorldJournal. 2012; 2012(?):973193. doi: 10.1100/2012/973193. [PMID: 22645489]
  • Isabela Ferrari Pereira Lima, Juliano De Dea Lindner, Vanete Thomaz Soccol, José Luiz Parada, Carlos Ricardo Soccol. Development of an innovative nutraceutical fermented beverage from herbal mate (Ilex paraguariensis A.St.-Hil.) extract. International journal of molecular sciences. 2012; 13(1):788-800. doi: 10.3390/ijms13010788. [PMID: 22312286]
  • Upanandan Mandal, Debasis De, Kazi Monjur Ali, Anjan Biswas, Debidas Ghosh. Effect of different solvent extracts of Benincasa hispida T. on experimental hypochlorhydria in rat. Journal of advanced pharmaceutical technology & research. 2012 Jan; 3(1):41-6. doi: 10.4103/2231-4040.93563. [PMID: 22470892]
  • H Filiz Ayyildiz, Huseyin Kara, S T H Sherazi. A novel approach for determination of free fatty acids in vegetable oils by a flow injection system with manual injection. Lipids. 2011 Dec; 46(12):1181-90. doi: 10.1007/s11745-011-3610-9. [PMID: 21904794]
  • Jhon Castañeda-Gómez, Rogelio Pereda-Miranda. Resin glycosides from the herbal drug jalap (Ipomoea purga). Journal of natural products. 2011 May; 74(5):1148-53. doi: 10.1021/np200080k. [PMID: 21446661]
  • Rhl Souza, Msp Cardoso, Ct Menezes, Jp Silva, Dp De Sousa, Js Batista. Gastroprotective activity of α-terpineol in two experimental models of gastric ulcer in rats. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. 2011; 19(4):277-81. doi: . [PMID: 22615669]
  • Deise Elizabeth Souza, Marcia Oliveira Pereira, Luciana Camargo Bernardo, Fernanda Santos Carmo, Adenilson de Souza da Fonseca, Mario Bernardo-Filho. An experimental model to study the effects of a senna extract on the blood constituent labeling and biodistribution of a radiopharmaceutical in rats. Clinics (Sao Paulo, Brazil). 2011; 66(3):483-6. doi: 10.1590/s1807-59322011000300021. [PMID: 21552677]
  • Dongming Lan, Shulin Hou, Ning Yang, Chris Whiteley, Bo Yang, Yonghua Wang. Optimal production and biochemical properties of a lipase from Candida albicans. International journal of molecular sciences. 2011; 12(10):7216-37. doi: 10.3390/ijms12107216. [PMID: 22072943]
  • Liang Sun, Mei Zhang, Jie Ren, Jianxun Qi, Guojun Zhang, Ping Leng. Reciprocity between abscisic acid and ethylene at the onset of berry ripening and after harvest. BMC plant biology. 2010 Nov; 10(?):257. doi: 10.1186/1471-2229-10-257. [PMID: 21092180]
  • Javier Terol, Guillermo Soler, Manuel Talon, Manuel Cercos. The aconitate hydratase family from Citrus. BMC plant biology. 2010 Oct; 10(?):222. doi: 10.1186/1471-2229-10-222. [PMID: 20958971]
  • Sp Roy, Cm Niranjan, Tm Jyothi, Mm Shankrayya, Km Vishawanath, K Prabhu, Va Gouda, Rs Setty. Antiulcer and Anti-inflammatory Activity of Aerial Parts Enicostemma littorale Blume. Journal of young pharmacists : JYP. 2010 Oct; 2(4):369-73. doi: 10.4103/0975-1483.71629. [PMID: 21264096]
  • Inderjit, Devika Bajpai, M S Rajeswari. Interaction of 8-hydroxyquinoline with soil environment mediates its ecological function. PloS one. 2010 Sep; 5(9):e12852. doi: 10.1371/journal.pone.0012852. [PMID: 20877629]
  • Olubunmi A Wintola, Taofik O Sunmonu, Anthony J Afolayan. The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats. BMC gastroenterology. 2010 Aug; 10(?):95. doi: 10.1186/1471-230x-10-95. [PMID: 20723249]
  • J Vaysse, S Balayssac, V Gilard, D Desoubdzanne, M Malet-Martino, R Martino. Analysis of adulterated herbal medicines and dietary supplements marketed for weight loss by DOSY 1H-NMR. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2010 Jul; 27(7):903-16. doi: 10.1080/19440041003705821. [PMID: 20437283]
  • Chunze Li, Bing Lu, Robert M Garbaccio, Edward S Tasber, Mark E Fraley, George D Hartman, Jingjing Ye, Jane C Harrelson, Thomayant Prueksaritanont. Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues. Biochemical pharmacology. 2010 May; 79(10):1526-33. doi: 10.1016/j.bcp.2010.01.024. [PMID: 20109439]
  • P Bharathi Dhasan, M Jegadeesan, S Kavimani. Antiulcer activity of aqueous extract of fruits of Momordica cymbalaria Hook f. in Wistar rats. Pharmacognosy research. 2010 Jan; 2(1):58-61. doi: 10.4103/0974-8490.60575. [PMID: 21808541]
  • Sunday Olakunle Idowu, Morenikeji Ambali Adeyemo, Udochi Ihechiluru Ogbonna. Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics. Journal of biological engineering. 2009 Sep; 3(?):14. doi: 10.1186/1754-1611-3-14. [PMID: 19735551]
  • V Singh, A Tiwari. Hydrolytic fragmentation of seed gums under microwave irradiation. International journal of biological macromolecules. 2009 Mar; 44(2):186-9. doi: 10.1016/j.ijbiomac.2008.12.003. [PMID: 19135082]
  • Juan Wang, Li-Ping Wang, Da-Jin Yang, Bo Chen. [A new method for safety monitoring of natural dietary supplements--quality profile]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 2008 Jul; 42(7):489-93. doi: ". [PMID: 19035183]
  • J Wang, B Chen, S Yao. Analysis of six synthetic adulterants in herbal weight-reducing dietary supplements by LC electrospray ionization-MS. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2008 Jul; 25(7):822-30. doi: 10.1080/02652030801946553. [PMID: 18569001]
  • Ibrahim Abdel Aziz Ibrahim, Kamisah Yusof, Nafeeza Mohd Ismail, Nur Azlina Mohd Fahami. Protective effect of palm vitamin E and α-tocopherol against gastric lesions induced by water immersion restraint stress in Sprague-Dawley rats. Indian journal of pharmacology. 2008 Mar; 40(2):73-7. doi: 10.4103/0253-7613.41042. [PMID: 21279170]
  • . The toxicology and carcinogenesis study of phenolphthalein (CAS No. 77-09-8) in genetically modified haploinsufficient p16(Ink4a)/p19(Arf) mice (feed study). National Toxicology Program genetically modified model report. 2007 Dec; ?(12):1-85. doi: . [PMID: 18784766]
  • I R Al'miev, O Larroche, D Benredjem, J Dubau, S Kazamias, C Möller, A Klisnick. Dynamical description of transient x-ray lasers seeded with high-order harmonic radiation through Maxwell-Bloch numerical simulations. Physical review letters. 2007 Sep; 99(12):123902. doi: 10.1103/physrevlett.99.123902. [PMID: 17930505]
  • Shanan S Tobe, Nigel Watson, Niamh Nic Daéid. Evaluation of six presumptive tests for blood, their specificity, sensitivity, and effect on high molecular-weight DNA. Journal of forensic sciences. 2007 Jan; 52(1):102-9. doi: 10.1111/j.1556-4029.2006.00324.x. [PMID: 17209919]
  • Rogelio Pereda-Miranda, Mabel Fragoso-Serrano, Edgar Escalante-Sanchez, Beatriz Hernandez-Carlos, Edelmira Linares, Robert Bye. Profiling of the resin glycoside content of Mexican jalap roots with purgative activity. Journal of natural products. 2006 Oct; 69(10):1460-6. doi: 10.1021/np060295f. [PMID: 17067162]
  • Yi Hong Fan, Bin Lu, Mei Wang, Gui Bao Ni, Ming Tao Chen, Yi Xu. Expression and significance of nerve growth factor receptor p75 in rats' cathartic colonic wall. Chinese journal of digestive diseases. 2006; 7(4):225-9. doi: 10.1111/j.1443-9573.2006.00274.x. [PMID: 17054585]
  • Shyama Chatterjee, Gunther Vrolix, Inge Depoortere, Theo Peeters, Eric Van Marck. The therapeutic effect of the neuropeptide hormone somatostatin on Schistosoma mansoni caused liver fibrosis. BMC infectious diseases. 2005 Jun; 5(?):45. doi: 10.1186/1471-2334-5-45. [PMID: 15949036]
  • Jochen Beyer, Frank T Peters, Hans H Maurer. Screening procedure for detection of stimulant laxatives and/or their metabolites in human urine using gas chromatography-mass spectrometry after enzymatic cleavage of conjugates and extractive methylation. Therapeutic drug monitoring. 2005 Apr; 27(2):151-7. doi: 10.1097/01.ftd.0000150878.36296.04. [PMID: 15795644]
  • Kiichiro Kagawa, Nasrullah Idris, Munehide Wada, Hendrik Kurniawan, Kenichiro Tsuyuki, Satoru Miura. Carbon analysis for inspecting carbonation of concrete using a TEA CO2 laser-induced plasma. Applied spectroscopy. 2004 Aug; 58(8):887-96. doi: 10.1366/0003702041655458. [PMID: 18070383]
  • Martin Bertau, Gerhard Jörg. Saccharides as efficacious solubilisers for highly lipophilic compounds in aqueous media. Bioorganic & medicinal chemistry. 2004 Jun; 12(11):2973-83. doi: 10.1016/j.bmc.2004.03.041. [PMID: 15142556]
  • Jian-Ying Hu, Takako Aizawa. Quantitative structure-activity relationships for estrogen receptor binding affinity of phenolic chemicals. Water research. 2003 Mar; 37(6):1213-22. doi: 10.1016/s0043-1354(02)00378-0. [PMID: 12598185]
  • L P Rivory, K A Slaviero, S J Clarke. Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response. British journal of cancer. 2002 Jul; 87(3):277-80. doi: 10.1038/sj.bjc.6600448. [PMID: 12177794]
  • Waseem Altaf, Shahana Perveen, Khalil U Rehman, Saul Teichberg, Ivana Vancurova, Rita G Harper, Raul A Wapnir. Zinc supplementation in oral rehydration solutions: experimental assessment and mechanisms of action. Journal of the American College of Nutrition. 2002 Feb; 21(1):26-32. doi: 10.1080/07315724.2002.10719190. [PMID: 11838884]
  • T Ban-nai, Y Muramatsu. Transfer factors of radioactive Cs, Sr, Mn, Co and Zn from Japanese soils to root and leaf of radish. Journal of environmental radioactivity. 2002; 63(3):251-64. doi: 10.1016/s0265-931x(02)00032-2. [PMID: 12440514]
  • V K Kanungo, S Sinha, M L Naik. Net primary productivity of some aquatic macrophytes in sewage-sullage mixture. Journal of environmental biology. 2001 Jul; 22(3):219-23. doi: ". [PMID: 12017265]
  • B J Collins, T B Grizzle, J K Dunnick. Toxicokinetics of phenolphthalein in male and female rats and mice. Toxicological sciences : an official journal of the Society of Toxicology. 2000 Aug; 56(2):271-81. doi: 10.1093/toxsci/56.2.271. [PMID: 10910984]
  • C E Garner, H B Matthews, L T Burka. Phenolphthalein metabolite inhibits catechol-O-methyltransferase-mediated metabolism of catechol estrogens: a possible mechanism for carcinogenicity. Toxicology and applied pharmacology. 2000 Jan; 162(2):124-31. doi: 10.1006/taap.1999.8830. [PMID: 10637136]
  • C Gruy-Kapral, M Emmett, C A Santa Ana, J L Porter, J S Fordtran, K D Fine. Effect of single dose resin-cathartic therapy on serum potassium concentration in patients with end-stage renal disease. Journal of the American Society of Nephrology : JASN. 1998 Oct; 9(10):1924-30. doi: 10.1681/asn.v9101924. [PMID: 9773794]
  • R J Griffin, V B Godfrey, L T Burka. Metabolism and disposition of phenolphthalein in male and female F344 rats and B6C3F1 mice. Toxicological sciences : an official journal of the Society of Toxicology. 1998 Apr; 42(2):73-81. doi: 10.1006/toxs.1997.2422. [PMID: 9579019]
  • H H Wenzl, K D Fine, C A Santa Ana, J L Porter, J S Fordtran. Effect of fludrocortisone and spironolactone on sodium and potassium losses in secretory diarrhea. Digestive diseases and sciences. 1997 Jan; 42(1):119-28. doi: 10.1023/a:1018897307835. [PMID: 9009126]
  • J K Dunnick, J R Hailey. Phenolphthalein exposure causes multiple carcinogenic effects in experimental model systems. Cancer research. 1996 Nov; 56(21):4922-6. doi: . [PMID: 8895745]
  • S B Rosalki. Beeting (sic) a crimson retreat. Lancet (London, England). 1996 Feb; 347(8999):474. doi: NULL. [PMID: 8618510]
  • M Emmett, R E Hootkins, K D Fine, C A Santa Ana, J L Porter, J S Fordtran. Effect of three laxatives and a cation exchange resin on fecal sodium and potassium excretion. Gastroenterology. 1995 Mar; 108(3):752-60. doi: 10.1016/0016-5085(95)90448-4. [PMID: 7875477]
  • B S Anand, E Torres, A Operkun, D Y Graham. Comparative assessment of phenolphthalein and phenolphthalein glucuronide: is phenolphthalein glucuronide a better laxative?. Alimentary pharmacology & therapeutics. 1994 Oct; 8(5):559-62. doi: 10.1111/j.1365-2036.1994.tb00331.x. [PMID: 7865650]
  • M D Green, E M Oturu, T R Tephly. Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. Drug metabolism and disposition: the biological fate of chemicals. 1994 Sep; 22(5):799-805. doi: NULL. [PMID: 7835232]
  • P M Copeland. Renal failure associated with laxative abuse. Psychotherapy and psychosomatics. 1994; 62(3-4):200-2. doi: 10.1159/000288923. [PMID: 7531354]
  • F Chen, J K Ritter, M G Wang, O W McBride, R A Lubet, I S Owens. Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms. Biochemistry. 1993 Oct; 32(40):10648-57. doi: 10.1021/bi00091a015. [PMID: 8399210]
  • S L Perkins, J F Livesey. A rapid high-performance thin-layer chromatographic urine screen for laxative abuse. Clinical biochemistry. 1993 Jun; 26(3):179-81. doi: 10.1016/0009-9120(93)90023-y. [PMID: 8330386]
  • J A Wilhelm, L C Bailey, T A Shepard, V S Venturella. Simultaneous determination of phenolphthalein and phenolphthalein glucuronide from dog serum, urine and bile by high-performance liquid chromatography. Journal of chromatography. 1992 Jul; 578(2):231-8. doi: 10.1016/0378-4347(92)80421-l. [PMID: 1400802]
  • D D Dietz, M R Elwell, R E Chapin, M D Shelby, M B Thompson, R Filler, M A Stedham. Subchronic (13-week) toxicity studies of oral phenolphthalein in Fischer 344 rats and B6C3F1 mice. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1992 Jan; 18(1):48-58. doi: 10.1016/0272-0590(92)90194-m. [PMID: 1601209]
  • K D Fine, C A Santa Ana, J S Fordtran. Diagnosis of magnesium-induced diarrhea. The New England journal of medicine. 1991 Apr; 324(15):1012-7. doi: 10.1056/nejm199104113241502. [PMID: 2005938]
  • J Morton. The detection of laxative abuse. Annals of clinical biochemistry. 1987 Jan; 24 ( Pt 1)(?):107-8. doi: 10.1177/000456328702400116. [PMID: 3827173]
  • L K Griffeth, G M Rosen, E J Rauckman. Effects of model traumatic injury on hepatic drug metabolism in the rat. IV. Glucuronidation. Drug metabolism and disposition: the biological fate of chemicals. 1985 Jul; 13(4):391-7. doi: . [PMID: 2863100]
  • R A Ahrens, S L Garland, H N Kigutha, E Russek. The disaccharide effect of sucrose feeding on glucuronide excretion and bile concentration of injected phenolphthalein in guinea pigs. The Journal of nutrition. 1985 Feb; 115(2):288-91. doi: 10.1093/jn/115.2.288. [PMID: 3968593]
  • D Haidukewych, E Rodin, S Schmaltz. Elevation of beta-glucuronidase activity in medicated patients with epilepsy. Therapeutic drug monitoring. 1984; 6(1):15-9. doi: 10.1097/00007691-198403000-00004. [PMID: 6710557]
  • E Elias, S Iqbal, S Knutton, A Hickey, R Coleman. Increased tight junction permeability: a possible mechanism of oestrogen cholestasis. European journal of clinical investigation. 1983 Oct; 13(5):383-90. doi: 10.1111/j.1365-2362.1983.tb00118.x. [PMID: 6416852]
  • R Baldassarri, G De Ritis, C Roscioni, F M Ceruso, D Cuscunà, E Moretti, M Passeggeri, S Passi, F Morabito. [Comparative clinical study of 3 drugs with laxative action]. La Clinica terapeutica. 1980 Jul; 94(1):67-75. doi: ". [PMID: 7438724]
  • P KRAMER, C E POPE. FACTITIOUS DIARRHEA INDUCED BY PHENOLPHTHALEIN. Archives of internal medicine. 1964 Nov; 114(?):634-6. doi: 10.1001/archinte.1964.03860110104010. [PMID: 14215990]
  • D C MARTIN, J J KAUFMAN. ACUTE HYDRONEPHROSIS MIMICKING RENAL COLIC. California medicine. 1964 Jun; 100(?):422-6. doi: NULL. [PMID: 14154288]
  • F SORRENTINO, C ROMANO. Tolerance test with phenolphthalein: study of its detoxication and of urinary beta-glucuronidase activity 'in vivo' in patients with bladder neoplasm. Urologia internationalis. 1961; 12(?):328-38. doi: 10.1159/000277582. [PMID: 13915320]
  • G GELMI. [Comparative examination between the luminol, phenolphthalein and benzidine reactions for the detection of blood in organic fluids]. Bollettino della Societa italiana di biologia sperimentale. 1960 Feb; 36(?):104-6. doi: NULL. [PMID: 13827233]
  • R J HENRY, N CHIAMORI, A G WARE. Determination of bromsulfonphthalein in serum by means of acetone precipitation of proteins. Technical bulletin of the Registry of Medical Technologists. American Society of Clinical Pathologists. Registry of Medical Technologists. 1959 Jul; 29(7):117-9. doi: NULL. [PMID: 13668904]
  • G FRAGLEN. The dye uptake of native and modified serum proteins. Clinica chimica acta; international journal of clinical chemistry. 1958 Jan; 3(1):63-7. doi: 10.1016/0009-8981(58)90057-3. [PMID: 13523840]
  • D SELIGSON, J MARINO, E DODSON. Determination of sulfobromophthalein in serum. Clinical chemistry. 1957 Oct; 3(5):638-45. doi: NULL. [PMID: 13473139]
  • F PARR, W SCHMITT. [The effect of acute changes in circulatory volume on serum concentration of bromsulphalein]. Zeitschrift fur klinische Medizin. 1957; 154(4):395-404. doi: NULL. [PMID: 13434272]
  • A J THERKELSEN. Effect of serum on spectral absorption of bromsulphthalein after intravenous injection of heparin. Scandinavian journal of clinical and laboratory investigation. 1957; 9(2):156-9. doi: 10.3109/00365515709101215. [PMID: 13442570]
  • K SCHILLING, H WALDMANN-MEYER. The interaction of bromophenol blue with serum albumin and gamma-globulin in acid medium. Archives of biochemistry and biophysics. 1956 Oct; 64(2):291-301. doi: 10.1016/0003-9861(56)90272-7. [PMID: 13363436]
  • K KNOPP. [The phenolsulfonphthalein test in determination of tubal patency]. Zentralblatt fur Gynakologie. 1956 Jul; 78(27):1045-7. doi: NULL. [PMID: 13353663]
  • M BJORNEBOE. [Fatal reaction in bromsulphalein test]. Ugeskrift for laeger. 1956 May; 118(16):447-8. doi: NULL. [PMID: 13352479]
  • Y BOQUIEN. [A determination on the elimination of phenolsulfonphthalein injected intraperitoneally for a study of cirrhotic ascites]. Archives des maladies de l'appareil digestif et des maladies de la nutrition. 1955 Nov; 44(11):1179-84. doi: NULL. [PMID: 13303556]
  • R P FORSTER, I SPERBER, J V TAGGART. Transport of phenolsulfonphthalein dyes in isolated tubules of the flounder and in kidney slices of the dogfish; competitive phenomena. Journal of cellular and comparative physiology. 1954 Oct; 44(2):315-8. doi: 10.1002/jcp.1030440212. [PMID: 13221614]
  • M E SPIRA. [Phenolsulfonphthalein test of oviduct patency]. Lekarsky obzor. 1954; 3(7-8):435-6. doi: NULL. [PMID: 13222918]
  • G HAND. [A simplified clearance method with phenolsulfonphthalein (phenolrot)]. Die Medizinische. 1953 Jul; 29-30(?):953-5. doi: NULL. [PMID: 13086254]
  • N F MACLAY. A spectrophotometric method for bromsulfalein determination in normal jaundiced and lipemic serum. The American journal of medical technology. 1953 Jul; 19(4):167-70. doi: NULL. [PMID: 13065306]
  • J VALLANCE-OWEN. The renal excretion of phenolsulphonphthalein as an aid to the diagnosis of previous hypertension. Lancet (London, England). 1953 Apr; 1(6763):721-3. doi: 10.1016/s0140-6736(53)91848-0. [PMID: 13036141]
  • G DRAGONI. [Effect of thyroxin on elimination of phenol red by the kidney in compensatory hypertrophy]. Bollettino della Societa italiana di biologia sperimentale. 1953 Mar; 29(3):301-3. doi: NULL. [PMID: 13081832]
  • H MAHNEKE. [The phenolsulfonphthalein test in sterility]. Nordisk medicin. 1953 Feb; 49(9):334-5. doi: NULL. [PMID: 13055040]
  • E K TILLSON, G S SCHUCHARDT. The determination of creatinine in plasma and urine in the presence of large amounts of phenol red. The Journal of laboratory and clinical medicine. 1953 Feb; 41(2):312-5. doi: NULL. [PMID: 13035267]
  • H MAHNEKE. [Attempts with the phenolsulfonphthalein test in sterility]. Nordisk medicin. 1953 Jan; 49(5):189-90. doi: NULL. [PMID: 13054995]
  • F A PEZOLD. [Binding of phenoltetrabromphthaleindisodium sulfonate to human serum in consideration of bromsulphalein test; paper-electrophoretic studies]. Zeitschrift fur die gesamte experimentelle Medizin. 1953; 121(6):600-13. doi: NULL. [PMID: 13137194]
  • A L C MAGGI, M MEEROFF, E IOVINE. [Quantitative Woldman reaction]. La Semana medica. 1952 Sep; 101(11):371-6. doi: NULL. [PMID: 13028621]