Protirelin (BioDeep_00000412685)
Main id: BioDeep_00000001466
BioNovoGene_Lab2019
代谢物信息卡片
holo-transferrin
化学式: C16H22N6O4 (362.1702)
中文名称: 普罗瑞林, 转铁蛋白, 促甲状腺素释放激素, 丙肝素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)N
InChI: InChI=1S/C16H22N6O4/c17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10/h7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25)/t10-,11-,12-/m0/s1
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C76367 - Thyrotropin-Releasing Hormone Analogue
V - Various > V04 - Diagnostic agents > V04C - Other diagnostic agents > V04CJ - Tests for thyreoidea function
A tripeptide composed of L-pyroglutamyl, L-histidyl and L-prolinamide residues joined in sequence.
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.
同义名列表
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:35940
- KEGG: C74244
- KEGG: C03958
- KEGGdrug: D00176
- PubChem: 638678
- DrugBank: DB09421
- ChEMBL: CHEMBL1472
- MeSH: Thyrotropin-Releasing Hormone
- CAS: 117217-40-0
- CAS: 11096-37-0
- CAS: 24305-27-9
- MoNA: MoNA016783
- MetaboLights: MTBLC35940
- PubChem: 6679
- 3DMET: B01705
- NIKKAJI: J3.473H
- medchemexpress: HY-P0002
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-164
- KNApSAcK: 35940
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jianan Wang, Shiying Liu, Yalei Xie, Chengli Xu. Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m.
Scientific reports.
2023 06; 13(1):9225. doi:
10.1038/s41598-023-35573-y. [PMID: 37286697] - Güldeniz Şekerci, Yavuz Erden, Suat Tekin. Effects of meteorin-like hormone on endocrine function of hypothalamo-hypophysial system and peripheral uncoupling proteins in rats.
Molecular biology reports.
2022 Jul; 49(7):5919-5925. doi:
10.1007/s11033-022-07374-5. [PMID: 35332411] - Kristen Thane, Cassandra Uricchio, Nicholas Frank. Effect of early or late blood sampling on thyrotropin releasing hormone stimulation test results in horses.
Journal of veterinary internal medicine.
2022 Mar; 36(2):770-777. doi:
10.1111/jvim.16362. [PMID: 35049089] - Yuri Kondo, Atsushi Ozawa, Daisuke Kohno, Kazuma Saito, Battsetseg Buyandalai, Sayaka Yamada, Kazuhiko Horiguchi, Yasuyo Nakajima, Nobuyuki Shibusawa, Akihiro Harada, Hideaki Yokoo, Hideo Akiyama, Tsutomu Sasaki, Tadahiro Kitamura, Masanobu Yamada. The Hypothalamic Paraventricular Nucleus Is the Center of the Hypothalamic-Pituitary-Thyroid Axis for Regulating Thyroid Hormone Levels.
Thyroid : official journal of the American Thyroid Association.
2022 01; 32(1):105-114. doi:
10.1089/thy.2021.0444. [PMID: 34726513] - Elena Alvarez-Salas, Aldo González, Maria Isabel Amaya, Patricia de Gortari. Accumbal TRH is downstream of the effects of isolation stress on hedonic food intake in rats.
Nutritional neuroscience.
2021 Jul; 24(7):554-563. doi:
10.1080/1028415x.2019.1657658. [PMID: 31438781] - Yoshimitsu Ouchi, Miko Yamato, Vishwajit S Chowdhury, Takashi Bungo. Adenosine 5'-monophosphate induces hypothermia and alters gene expressions in the brain and liver of chicks.
Brain research bulletin.
2021 07; 172(?):14-21. doi:
10.1016/j.brainresbull.2021.04.008. [PMID: 33862124] - Ana M P Campos, Frederick Wasinski, Marianne O Klein, Jackson C Bittencourt, Martin Metzger, Jose Donato. Fasting reduces the number of TRH immunoreactive neurons in the hypothalamic paraventricular nucleus of male rats, but not in mice.
Neuroscience letters.
2021 05; 752(?):135832. doi:
10.1016/j.neulet.2021.135832. [PMID: 33746008] - A Castillo-Campos, A Gutiérrez-Mata, J-L Charli, P Joseph-Bravo. Chronic stress inhibits hypothalamus-pituitary-thyroid axis and brown adipose tissue responses to acute cold exposure in male rats.
Journal of endocrinological investigation.
2021 Apr; 44(4):713-723. doi:
10.1007/s40618-020-01328-z. [PMID: 32734320] - Remona Horn, Allison J Stewart, Karen V Jackson, Elizabeth L Dryburgh, Carlos E Medina-Torres, François-René Bertin. Clinical implications of using adrenocorticotropic hormone diagnostic cutoffs or reference intervals to diagnose pituitary pars intermedia dysfunction in mature horses.
Journal of veterinary internal medicine.
2021 Jan; 35(1):560-570. doi:
10.1111/jvim.16017. [PMID: 33368633] - E L Oberhaus, D L Thompson, L E Kerrigan, A M Chapman. Plasma prolactin, thyroid-stimulating hormone, melanocyte-stimulating hormone, and adrenocorticotropin responses to thyrotropin-releasing hormone in mares treated with detomidine and butorphanol.
Domestic animal endocrinology.
2021 01; 74(?):106536. doi:
10.1016/j.domaniend.2020.106536. [PMID: 32871339] - Yuki Ebuchi, Toshihide Kubo, Mahoko Furujo, Yousuke Higuchi, Shoko Fujinaga, Hiroki Tsuchiya, Naoko Urata, Motoharu Ochi, Takahiro Namba, Narumi Hara, Michiko Kishi. Effect of growth hormone therapy on thyroid function in isolated growth hormone deficient and short small for gestational age children: a two-year study, including on assessment of the usefulness of the thyrotropin-releasing hormone (TRH) stimulation test.
Journal of pediatric endocrinology & metabolism : JPEM.
2020 Nov; 33(11):1417-1423. doi:
10.1515/jpem-2020-0151. [PMID: 33035188] - María Silvina Landa, Silvia Inés García, Mariano Luis Schuman, Ludmila Soledad Peres Diaz, Maia Aisicovich, Carlos José Pirola. Cardiovascular and body weight regulation changes in transgenic mice overexpressing thyrotropin-releasing hormone (TRH).
Journal of physiology and biochemistry.
2020 Nov; 76(4):599-608. doi:
10.1007/s13105-020-00765-x. [PMID: 32914279] - Kaoru Kobayashi, Yoshikazu Abe, Asuka Kawai, Takao Furihata, Takuro Endo, Hiroo Takeda. Pharmacokinetic Drug Interactions of an Orally Available TRH Analog (Rovatirelin) With a CYP3A4/5 and P-Glycoprotein Inhibitor (Itraconazole).
Journal of clinical pharmacology.
2020 10; 60(10):1314-1323. doi:
10.1002/jcph.1628. [PMID: 32459872] - Tegan A McGilvray, Edward J Knowles, Pat A Harris, Nicola J Menzies-Gow. Comparison of immunofluorescence and chemiluminescence assays for measuring ACTH in equine plasma.
Equine veterinary journal.
2020 Sep; 52(5):709-714. doi:
10.1111/evj.13227. [PMID: 31955443] - Siew Cheng Foong, May Loong Tan, Wai Cheng Foong, Lisa A Marasco, Jacqueline J Ho, Joo Howe Ong. Oral galactagogues (natural therapies or drugs) for increasing breast milk production in mothers of non-hospitalised term infants.
The Cochrane database of systematic reviews.
2020 05; 5(?):CD011505. doi:
10.1002/14651858.cd011505.pub2. [PMID: 32421208] - Ke Hu, Allison J Stewart, Ka Y Yuen, Sophia Hinrichsen, Elizabeth L Dryburgh, François-René Bertin. The effect of freeze-thaw cycles on determination of immunoreactive plasma adrenocorticotrophic hormone concentrations in horses.
Journal of veterinary internal medicine.
2020 May; 34(3):1350-1356. doi:
10.1111/jvim.15771. [PMID: 32255541] - Patricia Joseph-Bravo, Ivan Lazcano, Lorraine Jaimes-Hoy, Mariana Gutierrez-Mariscal, Edith Sanchez-Jaramillo, Rosa Maria Uribe, Jean-Louis Charli. Sexually dimorphic dynamics of thyroid axis activity during fasting in rats.
Frontiers in bioscience (Landmark edition).
2020 03; 25(7):1305-1323. doi:
10.2741/4857. [PMID: 32114434] - Rudolf Hoermann, Mark J Pekker, John E M Midgley, Rolf Larisch, Johannes W Dietrich. Triiodothyronine secretion in early thyroid failure: The adaptive response of central feedforward control.
European journal of clinical investigation.
2020 Feb; 50(2):e13192. doi:
10.1111/eci.13192. [PMID: 31815292] - Go Kuroda, Shigekazu Sasaki, Akio Matsushita, Kenji Ohba, Yuki Sakai, Shinsuke Shinkai, Hiroko Misawa Nakamura, Satoru Yamagishi, Kohji Sato, Naoko Hirahara, Yutaka Oki, Masahiko Ito, Tetsuro Suzuki, Takafumi Suda. G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus.
PloS one.
2020; 15(11):e0242380. doi:
10.1371/journal.pone.0242380. [PMID: 33201916] - Edina Varga, Erzsébet Farkas, Györgyi Zséli, Andrea Kádár, Alexandra Venczel, Dóra Kővári, Dorottya Németh, Zoltán Máté, Ferenc Erdélyi, András Horváth, Ottó Szenci, Masahiko Watanabe, Ronald M Lechan, Balázs Gereben, Csaba Fekete. Thyrotropin-Releasing-Hormone-Synthesizing Neurons of the Hypothalamic Paraventricular Nucleus Are Inhibited by Glycinergic Inputs.
Thyroid : official journal of the American Thyroid Association.
2019 12; 29(12):1858-1868. doi:
10.1089/thy.2019.0357. [PMID: 31659941] - Helena Kerp, Kathrin Engels, Frederike Kramer, Denica Doycheva, Georg Sebastian Hönes, Denise Zwanziger, Lars Christian Moeller, Heike Heuer, Dagmar Führer. Age effect on thyroid hormone brain response in male mice.
Endocrine.
2019 12; 66(3):596-606. doi:
10.1007/s12020-019-02078-6. [PMID: 31494803] - Elizabeth Hodge, Alycia Kowalski, Catherine Torcivia, Sue Lindborg, Darko Stefanovski, Kelsey Hart, Nicholas Frank, Andrew van Eps. Effect of thyrotropin-releasing hormone stimulation testing on the oral sugar test in horses when performed as a combined protocol.
Journal of veterinary internal medicine.
2019 Sep; 33(5):2272-2279. doi:
10.1111/jvim.15601. [PMID: 31432575] - Remona Horn, François-René Bertin. Evaluation of combined testing to simultaneously diagnose pituitary pars intermedia dysfunction and insulin dysregulation in horses.
Journal of veterinary internal medicine.
2019 Sep; 33(5):2249-2256. doi:
10.1111/jvim.15617. [PMID: 31498947] - D I Rendle, G Doran, J Ireland, S Edwards. Pharmacokinetics and pharmacodynamics of pergolide mesylate after oral administration in horses with pituitary pars intermedia dysfunction.
Domestic animal endocrinology.
2019 07; 68(?):135-141. doi:
10.1016/j.domaniend.2019.01.008. [PMID: 31082785] - Juliana Soares Severo, Jennifer Beatriz Silva Morais, Taynáh Emannuelle Coelho de Freitas, Ana Letícia Pereira Andrade, Mayara Monte Feitosa, Larissa Cristina Fontenelle, Ana Raquel Soares de Oliveira, Kyria Jayanne Clímaco Cruz, Dilina do Nascimento Marreiro. The Role of Zinc in Thyroid Hormones Metabolism.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
2019 Jul; 89(1-2):80-88. doi:
10.1024/0300-9831/a000262. [PMID: 30982439] - Babetta A Breuhaus. Thyroid Hormone and Thyrotropin Concentrations and Responses to Thyrotropin-Stimulating Hormone in Horses with PPID Compared with Age-Matched Normal Horses.
Journal of equine veterinary science.
2019 04; 75(?):35-40. doi:
10.1016/j.jevs.2019.01.008. [PMID: 31002090] - John P Dougherty, Danielle A Springer, Mary J Cullen, Marvin C Gershengorn. Evaluation of the effects of chemotherapy-induced fatigue and pharmacological interventions in multiple mouse behavioral assays.
Behavioural brain research.
2019 03; 360(?):255-261. doi:
10.1016/j.bbr.2018.12.011. [PMID: 30529403] - Kaoru Kobayashi, Yoshikazu Abe, Hiroshi Harada, Emiko Oota, Takuro Endo, Hiroo Takeda. Non-clinical pharmacokinetic profiles of rovatirelin, an orally available thyrotropin-releasing hormone analogue.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 Jan; 49(1):106-119. doi:
10.1080/00498254.2017.1423130. [PMID: 29300135] - Tera Pijnacker, Marieke Knies, Sara Galac, Karin Sanders, Jan A Mol, Hans S Kooistra. TRH-induced secretion of adrenocorticotropin and cortisol in dogs with pituitary-dependent hypercortisolism.
The veterinary quarterly.
2018 Dec; 38(1):72-78. doi:
10.1080/01652176.2018.1521537. [PMID: 30362899] - Umit Yilmaz, Suat Tekin, Mehmet Demir, Yilmaz Cigremis, Suleyman Sandal. Effects of central FGF21 infusion on the hypothalamus-pituitary-thyroid axis and energy metabolism in rats.
The journal of physiological sciences : JPS.
2018 Nov; 68(6):781-788. doi:
10.1007/s12576-018-0595-7. [PMID: 29417398] - Kazunori Kageyama, Satoru Sakihara, Wataru Kameda, Aya Sugiyama, Shinobu Takayasu, Ken Terui, Makoto Daimon. Evaluation of growth hormone-releasing peptide-2 for diagnosis of thyrotropin-producing pituitary adenomas.
Endocrine journal.
2018 Oct; 65(10):1049-1054. doi:
10.1507/endocrj.ej17-0527. [PMID: 29973439] - Fengjiao Zheng, Jingnan Han, Haocheng Lu, Changting Cui, Jichun Yang, Qinghua Cui, Jun Cai, Yong Zhou, Chaoshu Tang, Guoheng Xu, Bin Geng. Cystathionine beta synthase-hydrogen sulfide system in paraventricular nucleus reduced high fatty diet induced obesity and insulin resistance by brain-adipose axis.
Biochimica et biophysica acta. Molecular basis of disease.
2018 10; 1864(10):3281-3291. doi:
10.1016/j.bbadis.2018.07.014. [PMID: 30010047] - Masaki Nakano, Itaru Hasunuma, Atsuko Minagawa, Shawichi Iwamuro, Kazutoshi Yamamoto, Sakae Kikuyama, Takeo Machida, Tetsuya Kobayashi. Possible involvement of thyrotropin-releasing hormone receptor 3 in the release of prolactin in the metamorphosing bullfrog larvae.
General and comparative endocrinology.
2018 Oct; 267(?):36-44. doi:
10.1016/j.ygcen.2018.05.029. [PMID: 29864416] - Yanzhen Zhang, Chunfeng Wang, Lianfeng Zhang. The potential role of thyrotropin-releasing hormone in colonic dysmotility induced by water avoidance stress in rats.
Neuropeptides.
2018 Aug; 70(?):47-54. doi:
10.1016/j.npep.2018.05.005. [PMID: 29803395] - Charlotte A Heinen, Zhi Zhang, Lars P Klieverik, Tim C de Wit, Edwin Poel, Maqsood Yaqub, Anita Boelen, Andries Kalsbeek, Peter H Bisschop, A S Paul van Trotsenburg, Hein J Verberne, Jan Booij, Eric Fliers. Effects of intravenous thyrotropin-releasing hormone on 18F-fluorodeoxyglucose uptake in human brown adipose tissue: a randomized controlled trial.
European journal of endocrinology.
2018 Jul; 179(1):31-38. doi:
10.1530/eje-17-0966. [PMID: 29724865] - Tera Pijnacker, Hans S Kooistra, Cathelijne F Vermeulen, Merel van der Vinne, Marrit Prins, Sara Galac, Jan A Mol. Use of basal and TRH-stimulated plasma growth hormone concentrations to differentiate between primary hypothyroidism and nonthyroidal illness in dogs.
Journal of veterinary internal medicine.
2018 Jul; 32(4):1319-1324. doi:
10.1111/jvim.15139. [PMID: 29736988] - Di Sun, Liting Zhou, Shuyue Wang, Te Liu, Jian Zhu, Yiyang Jia, Jin Xu, Huaiji Chen, Qi Wang, Feng Xu, Yuezhu Zhang, Lin Ye. Correction and Republication: Effect of Di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-thyroid axis in adolescent rat.
Endocrine journal.
2018 03; 65(3):261-268. doi:
10.1507/endocrj.ej17-0272. [PMID: 29225205] - Radka Moravcova, Barbora Melkes, Jiri Novotny. TRH receptor mobility in the plasma membrane is strongly affected by agonist binding and by interaction with some cognate signaling proteins.
Journal of receptor and signal transduction research.
2018 Feb; 38(1):20-26. doi:
10.1080/10799893.2017.1398756. [PMID: 29137494] - Caroline Serrano-Nascimento, Jamile Calil-Silveira, Rafael Dalbosco, Telma Tenorio Zorn, Maria Tereza Nunes. Evaluation of hypothalamus-pituitary-thyroid axis function by chronic perchlorate exposure in male rats.
Environmental toxicology.
2018 Feb; 33(2):209-219. doi:
10.1002/tox.22509. [PMID: 29139221] - Zhi Zhang, Frederico Machado, Li Zhao, Charlotte A Heinen, Ewout Foppen, Mariette T Ackermans, Jiangning Zhou, Peter H Bisschop, Anita Boelen, Eric Fliers, Andries Kalsbeek. Administration of Thyrotropin-Releasing Hormone in the Hypothalamic Paraventricular Nucleus of Male Rats Mimics the Metabolic Cold Defense Response.
Neuroendocrinology.
2018; 107(3):267-279. doi:
10.1159/000492785. [PMID: 30092582] - John P Dougherty, Brian S Wolff, Mary J Cullen, Leorey N Saligan, Marvin C Gershengorn. Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue.
Pharmacological research.
2017 Oct; 124(?):1-8. doi:
10.1016/j.phrs.2017.07.012. [PMID: 28720519] - A G Kobylyanskii, Yu A Zolotarev, L A Andreeva, I A Grivennikov, N F Myasoedov. Studying the Toxic Effects of Some Biologically Active Peptides on the Model of Mouse Embryonic Stem Cells.
Bulletin of experimental biology and medicine.
2017 Oct; 163(6):731-736. doi:
10.1007/s10517-017-3891-y. [PMID: 29063333] - Naoko Iwata, Shintaro Iwama, Yoshihisa Sugimura, Yoshinori Yasuda, Kohtaro Nakashima, Seiji Takeuchi, Daisuke Hagiwara, Yoshihiro Ito, Hidetaka Suga, Motomitsu Goto, Ryoichi Banno, Patrizio Caturegli, Teruhiko Koike, Yoshiharu Oshida, Hiroshi Arima. Anti-pituitary antibodies against corticotrophs in IgG4-related hypophysitis.
Pituitary.
2017 Jun; 20(3):301-310. doi:
10.1007/s11102-016-0780-8. [PMID: 27896569] - Marc-Olivier Turgeon, Tanya L Silander, Denica Doycheva, Xiao-Hui Liao, Marc Rigden, Luisina Ongaro, Xiang Zhou, Sjoerd D Joustra, Jan M Wit, Mike G Wade, Heike Heuer, Samuel Refetoff, Daniel J Bernard. TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice.
Endocrinology.
2017 04; 158(4):815-830. doi:
10.1210/en.2016-1788. [PMID: 28324000] - E Pekary, A Sattin. TRH and TRH-Like Peptide Levels Co-Vary with Reproductive and Metabolic Rhythms.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
2017 Feb; 49(2):86-94. doi:
10.1055/s-0042-111012. [PMID: 27434852] - Yuki Inaba, Yuki Kato, Azumi Itou, Aoi Chiba, Ken Sawai, Ferenc Fülöp, György Miklos Nagy, Tsutomu Hashizume. Effects of extracerebral dopamine on salsolinol- or thyrotropin-releasing hormone-induced prolactin (PRL) secretion in goats.
Animal science journal = Nihon chikusan Gakkaiho.
2016 Dec; 87(12):1522-1527. doi:
10.1111/asj.12586. [PMID: 26997651] - Yardena Tenenbaum-Rakover, Marc-Olivier Turgeon, Shira London, Pia Hermanns, Joachim Pohlenz, Daniel J Bernard, Dani Bercovich. Familial Central Hypothyroidism Caused by a Novel IGSF1 Gene Mutation.
Thyroid : official journal of the American Thyroid Association.
2016 12; 26(12):1693-1700. doi:
10.1089/thy.2015.0672. [PMID: 27310681] - Satyendra K Rajput, Arun K Sharma, Chhuttan L Meena, Aditya B Pant, Rahul Jain, Shyam S Sharma. Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH2 against in-vitro and in-vivo models of cerebral ischemia and associated neurological disorders.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2016 Dec; 84(?):1256-1265. doi:
10.1016/j.biopha.2016.10.059. [PMID: 27810782] - Huimin Sui, Yue Wang, Xiaolei Zhang, Xiaolei Wang, Weina Cheng, Hongyang Su, Xu Wang, Xiaoying Sun, Xiao Xia Han, Bing Zhao, Yukihiro Ozaki. Ultrasensitive detection of thyrotropin-releasing hormone based on azo coupling and surface-enhanced resonance Raman spectroscopy.
The Analyst.
2016 Aug; 141(17):5181-8. doi:
10.1039/c6an00884d. [PMID: 27338554] - Lorraine Jaimes-Hoy, Mariana Gutiérrez-Mariscal, Yamili Vargas, Adrián Pérez-Maldonado, Fidelia Romero, Edith Sánchez-Jaramillo, Jean-Louis Charli, Patricia Joseph-Bravo. Neonatal Maternal Separation Alters, in a Sex-Specific Manner, the Expression of TRH, of TRH-Degrading Ectoenzyme in the Rat Hypothalamus, and the Response of the Thyroid Axis to Starvation.
Endocrinology.
2016 08; 157(8):3253-65. doi:
10.1210/en.2016-1239. [PMID: 27323240] - Melissa M Restifo, Nicholas Frank, Pilar Hermida, Alfredo Sanchez-Londoño. Effects of withholding feed on thyrotropin-releasing hormone stimulation test results and effects of combined testing on oral sugar test and thyrotropin-releasing hormone stimulation test results in horses.
American journal of veterinary research.
2016 Jul; 77(7):738-48. doi:
10.2460/ajvr.77.7.738. [PMID: 27347827] - T V Novoselova, R Larder, D Rimmington, C Lelliott, E H Wynn, R J Gorrigan, P H Tate, L Guasti, S O'Rahilly, A J L Clark, D W Logan, A P Coll, L F Chan. Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol.
The Journal of endocrinology.
2016 07; 230(1):13-26. doi:
10.1530/joe-16-0057. [PMID: 27106110] - E M de Vries, S Nagel, R Haenold, S M Sundaram, F W Pfrieger, E Fliers, H Heuer, A Boelen. The Role of Hypothalamic NF-κB Signaling in the Response of the HPT-Axis to Acute Inflammation in Female Mice.
Endocrinology.
2016 07; 157(7):2947-56. doi:
10.1210/en.2016-1027. [PMID: 27187176] - L Puga, V Alcántara-Alonso, U Coffeen, O Jaimes, P de Gortari. TRH injected into the nucleus accumbens shell releases dopamine and reduces feeding motivation in rats.
Behavioural brain research.
2016 06; 306(?):128-36. doi:
10.1016/j.bbr.2016.03.031. [PMID: 27006143] - José Ávila-Mendoza, Martha Carranza, Patricia Villalobos, Aurora Olvera, Aurea Orozco, Maricela Luna, Carlos Arámburo. Differential responses of the somatotropic and thyroid axes to environmental temperature changes in the green iguana.
General and comparative endocrinology.
2016 05; 230-231(?):76-86. doi:
10.1016/j.ygcen.2016.04.002. [PMID: 27044512] - Robert Krysiak, Małgorzata Gilowska, Witold Szkróbka, Bogusław Okopień. The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and amiodarone-induced hypothyroidism.
Pharmacological reports : PR.
2016 Apr; 68(2):490-4. doi:
10.1016/j.pharep.2015.11.010. [PMID: 26922558] - Elena Alvarez-Salas, Guadalupe Mengod, Cinthia García-Luna, Paulina Soberanes-Chávez, Gilberto Matamoros-Trejo, Patricia de Gortari. Mct8 and trh co-expression throughout the hypothalamic paraventricular nucleus is modified by dehydration-induced anorexia in rats.
Neuropeptides.
2016 Apr; 56(?):33-40. doi:
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International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience.
2015 Nov; 46(?):115-24. doi:
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The lancet. Diabetes & endocrinology.
2015 Oct; 3(10):816-25. doi:
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Research in veterinary science.
2015 Oct; 102(?):67-71. doi:
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Bioorganic & medicinal chemistry.
2015 Sep; 23(17):5641-53. doi:
10.1016/j.bmc.2015.07.022. [PMID: 26216015] - Lindsay Goodale, Nicholas Frank, Pilar Hermida, Sarah D'Oench. Evaluation of a thyrotropin-releasing hormone solution stored at room temperature for pituitary pars intermedia dysfunction testing in horses.
American journal of veterinary research.
2015 May; 76(5):437-44. doi:
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Life sciences.
2015 May; 128(?):1-7. doi:
10.1016/j.lfs.2015.02.002. [PMID: 25744395] - Joaquin Lado-Abeal. Thyroid hormones are needed to sustain 'inappropriately' normal TSH during non-thyroidal illness syndrome: a clinical observation in severely ill patients with primary hypothyroidism.
Neuro endocrinology letters.
2015; 36(1):41-7. doi:
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Journal of neuroendocrinology.
2014 Dec; 26(12):861-9. doi:
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Regulatory peptides.
2014 Nov; 194-195(?):30-5. doi:
10.1016/j.regpep.2014.10.002. [PMID: 25454367] - S Harvey, C Gineste, B D Gaylinn. Growth hormone (GH)-releasing activity of chicken GH-releasing hormone (GHRH) in chickens.
General and comparative endocrinology.
2014 Aug; 204(?):261-6. doi:
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Biofizika.
2014 Jul; 59(4):704-16. doi:
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Endocrinology.
2014 Jul; 155(7):2456-66. doi:
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Clinical endocrinology.
2014 May; 80(5):714-9. doi:
10.1111/cen.12336. [PMID: 24111551] - Rosa María Uribe, Lorraine Jaimes-Hoy, Candy Ramírez-Martínez, Arlene García-Vázquez, Fidelia Romero, Miguel Cisneros, Antonieta Cote-Vélez, Jean-Louis Charli, Patricia Joseph-Bravo. Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats.
Endocrinology.
2014 May; 155(5):2020-30. doi:
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The Journal of endocrinology.
2014 Apr; 221(1):77-88. doi:
10.1530/joe-13-0458. [PMID: 24464021] - Michael J Krashes, Bhavik P Shah, Joseph C Madara, David P Olson, David E Strochlic, Alastair S Garfield, Linh Vong, Hongjuan Pei, Mitsuko Watabe-Uchida, Naoshige Uchida, Stephen D Liberles, Bradford B Lowell. An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger.
Nature.
2014 Mar; 507(7491):238-42. doi:
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PloS one.
2014; 9(9):e108972. doi:
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Orphanet journal of rare diseases.
2013 Sep; 8(?):142. doi:
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Domestic animal endocrinology.
2013 May; 44(4):204-12. doi:
10.1016/j.domaniend.2013.03.001. [PMID: 23571008] - Sahzene Yavuz, Joyce D Linderman, Sheila Smith, Xiongce Zhao, Frank Pucino, Francesco S Celi. The dynamic pituitary response to escalating-dose TRH stimulation test in hypothyroid patients treated with liothyronine or levothyroxine replacement therapy.
The Journal of clinical endocrinology and metabolism.
2013 May; 98(5):E862-6. doi:
10.1210/jc.2012-4196. [PMID: 23585666] - Nanthakumar Thirunarayanan, Eshel A Nir, Bruce M Raaka, Marvin C Gershengorn. Thyrotropin-releasing hormone receptor type 1 (TRH-R1), not TRH-R2, primarily mediates taltirelin actions in the CNS of mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2013 May; 38(6):950-6. doi:
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The Journal of clinical investigation.
2013 Apr; 123(4):1492-500. doi:
10.1172/jci61231. [PMID: 23524969] - Tsutomu Hashizume, Tomoyoshi Yaegashi, Jin Jin, Ken Sawai, Ferenc Fülöp, György Miklos Nagy. Effects of melatonin on salsolinol-induced prolactin secretion in goats.
Animal science journal = Nihon chikusan Gakkaiho.
2013 Apr; 84(4):334-40. doi:
10.1111/asj.12002. [PMID: 23590508] - Walter Pierpaoli. Aging-reversing properties of thyrotropin-releasing hormone.
Current aging science.
2013 Feb; 6(1):92-8. doi:
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Molecular and cellular endocrinology.
2013 Jan; 365(2):139-45. doi:
10.1016/j.mce.2012.10.006. [PMID: 23103668] - Patricia Pazos, Luis Lima, Felipe F Casanueva, Carlos Diéguez, María C García. Interleukin 6 deficiency modulates the hypothalamic expression of energy balance regulating peptides during pregnancy in mice.
PloS one.
2013; 8(8):e72339. doi:
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PloS one.
2013; 8(9):e73596. doi:
10.1371/journal.pone.0073596. [PMID: 24023889] - Misaki Miyata, Masanori Yoshida, Junji Shinoda, Hironobu Sasano, Yutaka Oiso. A marked difference in the vasopressin responsiveness between the adrenal glands in a patient with adrenocorticotropin-independent macronodular adrenal hyperplasia.
Internal medicine (Tokyo, Japan).
2013; 52(10):1073-8. doi:
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Toxicology.
2012 Dec; 302(1):68-76. doi:
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Integrative cancer therapies.
2012 Dec; 11(4):327-36. doi:
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Regulatory peptides.
2012 Nov; 179(1-3):61-70. doi:
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Journal of animal science.
2012 Nov; 90(11):4042-54. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
2012 Sep; 109(37):14966-71. doi:
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Acta biochimica et biophysica Sinica.
2012 Aug; 44(8):641-9. doi:
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Clinical endocrinology.
2012 Aug; 77(2):255-61. doi:
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The Journal of clinical endocrinology and metabolism.
2012 Aug; 97(8):2741-7. doi:
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American journal of physiology. Endocrinology and metabolism.
2012 May; 302(10):E1189-97. doi:
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European journal of endocrinology.
2012 May; 166(5):839-45. doi:
10.1530/eje-11-1073. [PMID: 22307573] - Liese Mebis, An Eerdekens, Fabian Güiza, Leslie Princen, Sarah Derde, Yoo-Mee Vanwijngaerden, Ilse Vanhorebeek, Veerle M Darras, Greet Van den Berghe, Lies Langouche. Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study.
Endocrinology.
2012 Feb; 153(2):973-84. doi:
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Hypertension research : official journal of the Japanese Society of Hypertension.
2012 Feb; 35(2):157-65. doi:
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Cell structure and function.
2012; 37(1):1-12. doi:
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Endocrine journal.
2012; 59(10):867-79. doi:
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