Triamcinolone acetonide (BioDeep_00000408944)
Main id: BioDeep_00000001960
代谢物信息卡片
化学式: C24H31FO6 (434.2105)
中文名称: 曲安缩松, 曲安奈德
谱图信息:
最多检出来源 not specific(not specific) 0%
分子结构信息
SMILES: C(C3O)C(C4(C(=O)CO)5)(C(CC4OC(C)(C)O5)(C(C32F)([H])CCC(C2(C)1)=CC(=O)C=C1)[H])C
InChI: InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
D000893 - Anti-Inflammatory Agents
同义名列表
2 个代谢物同义名
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:71418
- KEGG: C08183
- KEGGdrug: D00983
- PubChem: 6436
- ChEMBL: CHEMBL1504
- MeSH: Triamcinolone Acetonide
- CAS: 76-25-5
- MoNA: WA002351
- MoNA: WA002350
- MoNA: WA002349
- MoNA: WA002348
- MoNA: WA002347
- MoNA: WA002346
- PubChem: 10383
- PDB-CCD: 1TA
- NIKKAJI: J55.714E
- RefMet: Triamcinolone acetonide
- KNApSAcK: 71418
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yunsheng Chen, Kun Chen, Shan Zhong, Jiaqiang Wang, Zhixi Yu, Xiyang Sun, Yue Wang, Yan Liu, Zheng Zhang. Transdermal Transfersome Nanogels Control Hypertrophic Scar Formation via Synergy of Macrophage Phenotype-Switching and Anti-Fibrosis Effect.
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
2024 Feb; 11(7):e2305468. doi:
10.1002/advs.202305468
. [PMID: 38064170] - Qing Lin, Xinyu Shan, Xiang Li, Zhenyu Luo, Xin Yu, Huihui Liu, Sijie Wang, Xiaoqi Zhao, Ying Zhu, Huanli Zhou, Lihua Luo, Jian You. Solvent Exchange-Motivated and Tunable in Situ Forming Implants Sustaining Triamcinolone Acetonide Release for Arthritis Treatment.
International journal of pharmaceutics.
2023 Sep; ?(?):123383. doi:
10.1016/j.ijpharm.2023.123383
. [PMID: 37678476] - Yane Gao, Qiuxin Wu, Jing Xu, Qingmei Tian, Xiaofeng Xie, Xiujuan Du, Hongsheng Bi. Management and follow-up of uveal effusion syndrome: a case report.
BMC ophthalmology.
2023 Aug; 23(1):355. doi:
10.1186/s12886-023-03078-x
. [PMID: 37574556] - Zhi-Yan Huang, Xu-Sheng Zhang, Wen-Qiao Gong, Juan Liu, Li-Juan Lu. [Cost-effectiveness analysis of Biyuan Tongqiao Granules combined with Triamcinolone Acetonide Nasal Spray in treatment of chronic rhinosinusitis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2023 Aug; 48(15):4237-4242. doi:
10.19540/j.cnki.cjcmm.20230318.501
. [PMID: 37802792] - Luigi Talarico, Simone Pepi, Surama Susino, Gemma Leone, Claudia Bonechi, Marco Consumi, Ilaria Clemente, Agnese Magnani. Design and Optimization of Solid Lipid Nanoparticles Loaded with Triamcinolone Acetonide.
Molecules (Basel, Switzerland).
2023 Jul; 28(15):. doi:
10.3390/molecules28155747
. [PMID: 37570717] - Minghuan He, Naijia Bao, Rui-Qun Qi, Yan Wu, Min Liu. A randomized, prospective pilot study for comparison of a triple combination of 2940 nm Er:YAG Laser and triamcinolone acetonide solution with either 308 nm excimer laser or 0.1\% tacrolimus in treatment of stable segmental vitiligo.
Dermatologic therapy.
2022 11; 35(11):e15875. doi:
10.1111/dth.15875
. [PMID: 36181292] - José Carlos Nunes-Tamashiro, Jamil Natour, Fernando Maier Ramuth, Sandra Regina Toffolo, Jamile Godoy Mendes, André Rosenfeld, Rita Nely Vilar Furtado. Intra-articular injection with platelet-rich plasma compared to triamcinolone hexacetonide or saline solution in knee osteoarthritis: A double blinded randomized controlled trial with one year follow-up.
Clinical rehabilitation.
2022 Jul; 36(7):900-915. doi:
10.1177/02692155221090407
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The British journal of ophthalmology.
2022 06; 106(6):802-806. doi:
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The Journal of dermatological treatment.
2022 Jun; 33(4):2051-2056. doi:
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Clinical and experimental dental research.
2022 Jun; 8(3):707-714. doi:
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Indian journal of ophthalmology.
2022 05; 70(5):1736-1741. doi:
10.4103/ijo.ijo_2228_21
. [PMID: 35502063] - El-Sayed Shaaban Hewedy, Basma El-Saeed Ibrahim Sabaa, Wesam Salah Mohamed, Doaa Salah Hegab. Combined intralesional triamcinolone acetonide and platelet rich plasma versus intralesional triamcinolone acetonide alone in treatment of keloids.
The Journal of dermatological treatment.
2022 Feb; 33(1):150-156. doi:
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. [PMID: 32063079] - ShaoFeng Wu, Jing Fang, Fang Yu, Fang Han, Jun Xiao. Clinical Study of Intravitreal Injection of Anti-VEGF Drugs Combined with Triamcinolone Acetonide in the Treatment of Coats Disease.
Computational and mathematical methods in medicine.
2022; 2022(?):9911549. doi:
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Instructional course lectures.
2022; 71(?):119-134. doi:
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. [PMID: 35254778] - Wenjuan Wang, Xin Wang, Hongran Zhao, Yan Cui. A Case Report of Sweet's Syndrome with Panuveitis and Rhegmatogenous Retinal Detachment.
Ocular immunology and inflammation.
2021 Nov; 29(7-8):1345-1347. doi:
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JAMA otolaryngology-- head & neck surgery.
2021 11; 147(11):974-980. doi:
10.1001/jamaoto.2021.2492
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BMJ open.
2021 06; 11(6):e047548. doi:
10.1136/bmjopen-2020-047548
. [PMID: 34108168] - Rakhee Kapadia, Kinjal Parikh, Mahendra Jain, Krutika Sawant. Topical instillation of triamcinolone acetonide-loaded emulsomes for posterior ocular delivery: statistical optimization and in vitro-in vivo studies.
Drug delivery and translational research.
2021 06; 11(3):984-999. doi:
10.1007/s13346-020-00810-8
. [PMID: 32567039] - Yomna Mazid El-Hamd Neinaa, Toka Ahmad Elsayed, Dareen Ali Mohamed, Nashwa Naeem Elfar. Botulinum toxin and platelet rich plasma as innovative therapeutic modalities for keloids.
Dermatologic therapy.
2021 05; 34(3):e14900. doi:
10.1111/dth.14900
. [PMID: 33605002] - Erkan Yıldız. Triple treatment in ear keloids: Comparison of post-excisional intralesional steroid and platelet-rich plasma treatment.
American journal of otolaryngology.
2021 May; 42(3):102935. doi:
10.1016/j.amjoto.2021.102935
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Cell reports.
2021 04; 35(4):109040. doi:
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Materials science & engineering. C, Materials for biological applications.
2021 Feb; 119(?):111398. doi:
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. [PMID: 33321575] - Dalia S Saif, Nagwa N Hegazy, Enas S Zahran. Evaluating the Efficacy of Intra-articular Injections of Platelet Rich Plasma (PRP) in Rheumatoid Arthritis Patients and its Impact on Inflammatory Cytokines, Disease Activity and Quality of Life.
Current rheumatology reviews.
2021; 17(2):232-241. doi:
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Equine veterinary journal.
2021 Jan; 53(1):78-84. doi:
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Dermatologic therapy.
2020 11; 33(6):e14388. doi:
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. [PMID: 33034942] - Andrejs Elksniņš-Finogejevs, Luis Vidal, Andrejs Peredistijs. Intra-articular platelet-rich plasma vs corticosteroids in the treatment of moderate knee osteoarthritis: a single-center prospective randomized controlled study with a 1-year follow up.
Journal of orthopaedic surgery and research.
2020 Jul; 15(1):257. doi:
10.1186/s13018-020-01753-z
. [PMID: 32650801] - Ricardo Ruiz-Lopez, Yu-Chuan Tsai. A Randomized Double-Blind Controlled Pilot Study Comparing Leucocyte-Rich Platelet-Rich Plasma and Corticosteroid in Caudal Epidural Injection for Complex Chronic Degenerative Spinal Pain.
Pain practice : the official journal of World Institute of Pain.
2020 07; 20(6):639-646. doi:
10.1111/papr.12893
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Clinical and experimental dermatology.
2020 Jul; 45(5):549-554. doi:
10.1111/ced.14161
. [PMID: 32410250] - Pradip Nirbhavane, Gajanand Sharma, Bhupinder Singh, Ghazala Begum, Marie-Christine Jones, Saaeha Rauz, Rachel Vincent, Alastair K Denniston, Lisa J Hill, O P Katare. Triamcinolone acetonide loaded-cationic nano-lipoidal formulation for uveitis: Evidences of improved biopharmaceutical performance and anti-inflammatory activity.
Colloids and surfaces. B, Biointerfaces.
2020 Jun; 190(?):110902. doi:
10.1016/j.colsurfb.2020.110902
. [PMID: 32143010] - Qingyu Yao, Yuchen Guo, Junsheng Xue, Daming Kong, Jian Li, Xiuyun Tian, Chunyi Hao, Tianyan Zhou. Development and validation of a LC-MS/MS method for simultaneous determination of six glucocorticoids and its application to a pharmacokinetic study in nude mice.
Journal of pharmaceutical and biomedical analysis.
2020 Feb; 179(?):112980. doi:
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. [PMID: 31744668] - M L Formica, G V Ullio Gamboa, L I Tártara, J D Luna, J P Benoit, S D Palma. Triamcinolone acetonide-loaded lipid nanocapsules for ophthalmic applications.
International journal of pharmaceutics.
2020 Jan; 573(?):118795. doi:
10.1016/j.ijpharm.2019.118795
. [PMID: 31682964] - Kenji Sugibayashi, Nao Yamamoto, Shoko Itakura, Akie Okada, Ichiro Hijikuro, Hiroaki Todo. Development of Spray Formulations Applied to the Oral Mucosa Using Non-lamellar Liquid Crystal-Forming Lipids.
Chemical & pharmaceutical bulletin.
2020; 68(11):1025-1033. doi:
10.1248/cpb.c20-00333
. [PMID: 33132369] - Andreas Hoeflich, Brit Fitzner, Christina Walz, Michael Hecker, Armin Tuchscherer, Julia Brenmoehl, Uwe Klaus Zettl. Reduced Fragmentation of IGFBP-2 and IGFBP-3 as a Potential Mechanism for Decreased Ratio of IGF-II to IGFBPs in Cerebrospinal Fluid in Response to Repeated Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis.
Frontiers in endocrinology.
2020; 11(?):565557. doi:
10.3389/fendo.2020.565557
. [PMID: 33469444] - A Bessonnat, K Picotte, J P Lavoie. Intra-articular triamcinolone acetonide improves lung function in horses with severe asthma.
Equine veterinary journal.
2020 Jan; 52(1):131-135. doi:
10.1111/evj.13128
. [PMID: 31006122] - Aylin Sari, Ali Eroglu. Comparison of ultrasound-guided platelet-rich plasma, prolotherapy, and corticosteroid injections in rotator cuff lesions.
Journal of back and musculoskeletal rehabilitation.
2020; 33(3):387-396. doi:
10.3233/bmr-191519
. [PMID: 31743987] - Andreas Hoeflich, Brit Fitzner, Christina Walz, Michael Hecker, Armin Tuchscherer, Manuela Bastian, Julia Brenmoehl, Ina Schröder, Holger S Willenberg, Martin Reincke, Uwe Klaus Zettl. Systemic Effects by Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis.
Frontiers in endocrinology.
2020; 11(?):574. doi:
10.3389/fendo.2020.00574
. [PMID: 32982971] - Sergi Coll, Xavier Matabosch, Jone Llorente-Onaindia, Marcel Li Carbó, Clara Pérez-Mañá, Nuria Monfort, Jordi Monfort, Rosa Ventura. Elimination profile of triamcinolone hexacetonide and its metabolites in human urine and plasma after a single intra-articular administration.
Drug testing and analysis.
2019 Nov; 11(11-12):1589-1600. doi:
10.1002/dta.2614
. [PMID: 31087549] - Sergi Coll, Núria Monfort, Élida Alechaga, Xavier Matabosch, Clara Pérez-Mañá, Rosa Ventura. Additional studies on triamcinolone acetonide use and misuse in sports: Elimination profile after intranasal and high-dose intramuscular administrations.
Steroids.
2019 11; 151(?):108464. doi:
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. [PMID: 31344406] - Giulia Di Prima, Mariano Licciardi, Francesco Carfì Pavia, Attilio Ignazio Lo Monte, Gennara Cavallaro, Gaetano Giammona. Microfibrillar polymeric ocular inserts for triamcinolone acetonide delivery.
International journal of pharmaceutics.
2019 Aug; 567(?):118459. doi:
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The Journal of craniofacial surgery.
2019 Jun; 30(4):1144-1148. doi:
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. [PMID: 31166260] - Dadong Guo, Qin Li, Yuanyuan Sun, Junguo Guo, Qing Zhao, Xuewei Yin, Huixia Wei, Shanshan Wu, Hongsheng Bi. Evaluation of controlled-release triamcinolone acetonide-loaded mPEG-PLGA nanoparticles in treating experimental autoimmune uveitis.
Nanotechnology.
2019 Apr; 30(16):165702. doi:
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. [PMID: 30641491] - Zhenmiao Qin, Feng Chen, Demei Chen, Yong Wang, Yinfeng Tan, Junfeng Ban. Transdermal permeability of triamcinolone acetonide lipid nanoparticles.
International journal of nanomedicine.
2019; 14(?):2485-2495. doi:
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Journal of cosmetic dermatology.
2018 Dec; 17(6):1130-1135. doi:
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. [PMID: 29411520] - Devesh Kumawat, Vinod Kumar. Double trouble: exudative hypertensive retinopathy in a patient with retinitis pigmentosa.
BMJ case reports.
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. [PMID: 30413460] - Rozalin R Dickson, Joel M Reid, Wayne T Nicholson, Tim J Lamer, W Michael Hooten. Corticosteroid and Cortisol Serum Levels Following Intra-articular Triamcinolone Acetonide Lumbar Facet Joint Injections.
Pain practice : the official journal of World Institute of Pain.
2018 09; 18(7):864-870. doi:
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. [PMID: 29436106] - Wei Sun, Stacy Ho, Xiaojun Rick Fang, Thomas O'Shea, Hanlan Liu. Simultaneous determination of triamcinolone hexacetonide and triamcinolone acetonide in rabbit plasma using a highly sensitive and selective UPLC-MS/MS method.
Journal of pharmaceutical and biomedical analysis.
2018 May; 153(?):267-273. doi:
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. [PMID: 29550043] - Mohamed Hussein Medhat El-Komy, Noha Adly Saleh, Marwah Adly Saleh. Autologous platelet-rich plasma and triamcinolone acetonide intralesional injection in the treatment of oral erosions of pemphigus vulgaris: a pilot study.
Archives of dermatological research.
2018 May; 310(4):375-381. doi:
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Molecules (Basel, Switzerland).
2018 Apr; 23(4):. doi:
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. [PMID: 29690622] - Suparuj Lueangarun, Therdpong Tempark. Efficacy of MAS063DP lotion vs 0.02\% triamcinolone acetonide lotion in improving post-ablative fractional CO2 laser resurfacing wound healing: a split-face, triple-blinded, randomized, controlled trial.
International journal of dermatology.
2018 Apr; 57(4):480-487. doi:
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Rheumatology international.
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Osteoarthritis and cartilage.
2018 01; 26(1):34-42. doi:
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Journal of laparoendoscopic & advanced surgical techniques. Part A.
2017 Nov; 27(11):1217-1221. doi:
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Artificial cells, nanomedicine, and biotechnology.
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Medicina oral, patologia oral y cirugia bucal.
2017 Mar; 22(2):e159-e166. doi:
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Equine veterinary journal.
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Biomaterials.
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