cyclic amp (BioDeep_00000399978)

Main id: BioDeep_00000002927

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


Adenosine-3,5-cyclicmonophosphate

化学式: C10H12N5O6P (329.0525)
中文名称: 腺苷-3,5-环磷酸, 腺苷-3-5-环磷酸, 腺苷-3',5'-环单磷酸 钠盐 一水合物, 腺苷-3',5'-环单磷酸, 环磷酸腺苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OP(=O)(O1)O
InChI: InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6+,7+,10+/m1/s1

描述信息

COVID info from PDB, Protein Data Bank
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
CONFIDENCE standard compound; INTERNAL_ID 127
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes[1][2][3].
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes[1][2][3].
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes[1][2][3].

同义名列表

9 个代谢物同义名

Adenosine cyclic phosphate; cyclic amp; "3,5-CYCLIC AMP"; CAMP; Adenosine-3,5-cyclicmonophosphate; Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; 3',5'-Cyclic AMP; Cyclic AMP



数据库引用编号

43 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

42 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 CALCA, GNAQ, MYLK, PIK3C3, POMC, PRKAR1A, PTGS2, TH, TNK1
Peripheral membrane protein 2 PTGS2, TNK1
Endosome membrane 1 CLCN5
Endoplasmic reticulum membrane 1 PTGS2
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 2 GNAQ, TH
autophagosome 1 PIK3C3
cytosol 7 CLCN5, MYLK, PIK3C3, PRKAR1A, PRKCQ, SST, TH
dendrite 1 TH
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 1 PRKAR1A
Cell membrane 5 CLCN5, GNAQ, PRKAR1A, PTGER2, SCN2A
Lipid-anchor 1 GNAQ
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
Cell projection, axon 1 TH
Multi-pass membrane protein 4 CACNA1I, CLCN5, PTGER2, SCN2A
Golgi apparatus membrane 1 CLCN5
Synapse 3 CRH, GNAQ, MYLK
glutamatergic synapse 3 PIK3C3, PRKAR1A, SCN2A
Golgi apparatus 2 CLCN5, GNAQ
Golgi membrane 1 CLCN5
lysosomal membrane 2 CLCN5, GNAQ
neuromuscular junction 1 PRKAR1A
neuronal cell body 2 CALCA, SST
presynaptic membrane 1 SCN2A
smooth endoplasmic reticulum 1 TH
synaptic vesicle 2 CLCN5, TH
endosome 1 PIK3C3
plasma membrane 10 CACNA1I, CLCN5, GNAQ, IFNLR1, MYLK, PRKAR1A, PRKCQ, PTGER2, SCN2A, TNK1
terminal bouton 2 CALCA, TH
Membrane 9 CACNA1I, CLCN5, GNAQ, IFNLR1, PIK3C3, PRKAR1A, PTGER2, SCN2A, TNK1
axon 2 SCN2A, TH
caveola 1 PTGS2
extracellular exosome 1 GNAQ
endoplasmic reticulum 1 PTGS2
extracellular space 6 CALCA, CRH, IL2, POMC, PTH, SST
perinuclear region of cytoplasm 1 TH
intercalated disc 1 SCN2A
mitochondrion 1 TH
protein-containing complex 2 PRKAR1A, PTGS2
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 1 IFNLR1
Secreted 6 ADCYAP1, CALCA, CRH, IL2, POMC, SST
extracellular region 7 ADCYAP1, CALCA, CRH, IL2, POMC, PTH, SST
cytoplasmic side of plasma membrane 1 TH
hippocampal mossy fiber to CA3 synapse 1 CALCA
centriolar satellite 1 PRKCQ
photoreceptor outer segment 1 GNAQ
Nucleus membrane 1 GNAQ
nuclear membrane 1 GNAQ
varicosity 1 CRH
multivesicular body 1 PRKAR1A
actin cytoskeleton 1 MYLK
T-tubule 1 SCN2A
neuronal dense core vesicle lumen 1 CRH
perikaryon 3 ADCYAP1, CRH, TH
cytoplasmic vesicle 1 TH
Melanosome membrane 1 TH
midbody 1 PIK3C3
Early endosome 1 CLCN5
apical part of cell 1 CLCN5
Cell projection, lamellipodium 1 MYLK
Cytoplasm, perinuclear region 1 TH
GABA-ergic synapse 2 PIK3C3, SST
Peroxisome 1 PIK3C3
secretory granule 1 POMC
axoneme 1 PIK3C3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 PIK3C3
neuron projection 3 ADCYAP1, PTGS2, TH
ciliary base 1 PRKAR1A
phagocytic vesicle membrane 1 PIK3C3
heterotrimeric G-protein complex 1 GNAQ
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
stress fiber 1 MYLK
plasma membrane raft 1 PRKAR1A
secretory granule lumen 1 POMC
endoplasmic reticulum lumen 1 PTGS2
voltage-gated calcium channel complex 1 CACNA1I
node of Ranvier 1 SCN2A
paranode region of axon 1 SCN2A
immunological synapse 1 PRKCQ
presynaptic endosome 1 PIK3C3
neuronal dense core vesicle 2 CALCA, SST
aggresome 1 PRKCQ
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
nucleotide-activated protein kinase complex 1 PRKAR1A
voltage-gated sodium channel complex 1 SCN2A
postsynaptic endosome 1 PIK3C3
Autolysosome 1 PIK3C3
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
cAMP-dependent protein kinase complex 1 PRKAR1A
sperm head-tail coupling apparatus 1 PRKAR1A
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Chunhua Gao, Zhe Wang, Xiaojing Liu, Rongzhen Sun, Shengyao Ma, Zongchen Ma, Qi Wang, Guoqiang Li, Han-Ting Zhang. The Construction and Application of a New Screening Method for Phosphodiesterase Inhibitors. Biosensors. 2024 May; 14(5):. doi: 10.3390/bios14050252. [PMID: 38785726]
  • Guido Domingo, Milena Marsoni, Eleonora Davide, Stefania Fortunato, Maria Concetta de Pinto, Marcella Bracale, Gianluca Molla, Chris Gehring, Candida Vannini. The cAMP-dependent phosphorylation footprint in response to heat stress. Plant cell reports. 2024 May; 43(6):137. doi: 10.1007/s00299-024-03213-y. [PMID: 38713285]
  • Laura Yunuen Hernández-Sánchez, María Eva González-Trujano, Diego A Moreno, David Martínez-Vargas, Heike Vibrans, Alberto Hernandez-Leon, Alejandro Dorazco-González, Francisco Pellicer, Marcos Soto-Hernández. Antinociceptive effects of Raphanus sativus sprouts involve the opioid and 5-HT1A serotonin receptors, cAMP/cGMP pathways, and the central activity of sulforaphane. Food & function. 2024 May; 15(9):4773-4784. doi: 10.1039/d3fo05229j. [PMID: 38469873]
  • Alexander J Dear, Gonzalo A Garcia, Georg Meisl, Galen A Collins, Tuomas P J Knowles, Alfred L Goldberg. Maximum entropy determination of mammalian proteome dynamics. Proceedings of the National Academy of Sciences of the United States of America. 2024 Apr; 121(18):e2313107121. doi: 10.1073/pnas.2313107121. [PMID: 38652742]
  • Chiaki Yamamoto, Fumio Takahashi, Noriyuki Suetsugu, Kazumasa Yamada, Shinya Yoshikawa, Takayuki Kohchi, Masahiro Kasahara. The cAMP signaling module regulates sperm motility in the liverwort Marchantia polymorpha. Proceedings of the National Academy of Sciences of the United States of America. 2024 Apr; 121(16):e2322211121. doi: 10.1073/pnas.2322211121. [PMID: 38593080]
  • Milan Sencanski, Sanja Glisic, Valentina Kubale, Marko Cotman, Janez Mavri, Milka Vrecl. Computational Modeling and Characterization of Peptides Derived from Nanobody Complementary-Determining Region 2 (CDR2) Targeting Active-State Conformation of the β2-Adrenergic Receptor (β2AR). Biomolecules. 2024 Mar; 14(4):. doi: 10.3390/biom14040423. [PMID: 38672440]
  • Yidong Cai, Jinggang Dong, Jianqiang Huang, Jiaojiao He, Yonghua Hu, Zhihai Sui, Ping Tang. The cyclic AMP (cAMP) phosphodiesterase CpdA required for growth, biofilm formation, motility and pathogenicity of Edwardsiella piscicida. Microbial pathogenesis. 2024 Mar; 188(?):106545. doi: 10.1016/j.micpath.2024.106545. [PMID: 38244636]
  • Xuemeng Zhao, Wen Li, Xiliu Li, Zhenhua Jia, Shuishan Song, Qian Zhao. The Effect of Bacterial AHL on the Cyclic Adenosine Monophosphate Content in Plants According to High-Performance Liquid Chromatography. Molecules (Basel, Switzerland). 2024 Feb; 29(5):. doi: 10.3390/molecules29051074. [PMID: 38474586]
  • Zihan Li, Chengshan Zhu, Cong Yin, Heyu Li, Yimei Liu, Juan Li. Multi-omics reveals the testosterone promotion effect mechanism of Cordyceps Sobolifera on leydig cells. Journal of ethnopharmacology. 2024 Feb; ?(?):117817. doi: 10.1016/j.jep.2024.117817. [PMID: 38316217]
  • Xueli Cao, Yu Xiao, Erin Huiting, Xujun Cao, Dong Li, Jie Ren, Iana Fedorova, Hao Wang, Linlin Guan, Yu Wang, Lingyin Li, Joseph Bondy-Denomy, Yue Feng. Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides. Molecular cell. 2024 Jan; 84(2):375-385.e7. doi: 10.1016/j.molcel.2023.11.026. [PMID: 38103556]
  • Hongying Zhang, Yongliang Liu, Jieya Liu, Jinzhu Chen, Jiao Wang, Hui Hua, Yangfu Jiang. cAMP-PKA/EPAC signaling and cancer: the interplay in tumor microenvironment. Journal of hematology & oncology. 2024 Jan; 17(1):5. doi: 10.1186/s13045-024-01524-x. [PMID: 38233872]
  • Caitlyn Henry, Mackenzie Wilcox, Angela L Asirvatham. Forskolin-mediated cAMP activation upregulates TNF-α expression despite NF-κB downregulation in LPS-treated Schwann cells. PloS one. 2024; 19(4):e0302223. doi: 10.1371/journal.pone.0302223. [PMID: 38625986]
  • Ilona Turek, Chris Gehring. Peptide-Mediated Cyclic Nucleotide Signaling in Plants: Identification and Characterization of Interactor Proteins with Nucleotide Cyclase Activity. Methods in molecular biology (Clifton, N.J.). 2024; 2731(?):179-204. doi: 10.1007/978-1-0716-3511-7_14. [PMID: 38019435]
  • Yon-Suk Kim, Eun-Bin Lee, Ye-Ji Yu, Ga-Won Kim, Woo-Jung Kim, Dong-Kug Choi. Ethyl Acetate Fraction from a Catalpa ovata G. Don Extract Inhibits ɑ-MSH-Induced Melanogenesis through the cAMP/CREB Pathway. International journal of molecular sciences. 2023 Dec; 25(1):. doi: 10.3390/ijms25010151. [PMID: 38203322]
  • Huang Xi, Xia Youguang, Han Kai, Q I Weiwei, Linghu Qing, Zhang Qing, Xue Jingbo. Hetong decoction relieves loperamide-induced constipation in rats by regulating expression of aquaporins. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2023 Oct; 43(6):1160-1167. doi: 10.19852/j.cnki.jtcm.2023.06.008. [PMID: 37946478]
  • Robin Klein, Jannis Brehm, Juliane Wissig, Ralf Heermann, Gottfried Unden. A signaling complex of adenylate cyclase CyaC of Sinorhizobium meliloti with cAMP and the transcriptional regulators Clr and CycR. BMC microbiology. 2023 08; 23(1):236. doi: 10.1186/s12866-023-02989-5. [PMID: 37633907]
  • Zhihui Sun, Yan Tie, Xinyi Tong, Mingchang Cheng, Yushan Wu, Pingxiang Xu, Ming Xue, Liping Xu, Xuelin Zhou. Multi-omics approaches revealed the therapeutic mechanisms of Suo-Quan-Wan for treating overactive bladder in spontaneously hypertensive rats. Journal of ethnopharmacology. 2023 Aug; 318(Pt B):117066. doi: 10.1016/j.jep.2023.117066. [PMID: 37604331]
  • Guido Domingo, Milena Marsoni, Luca Chiodaroli, Stefania Fortunato, Marcella Bracale, Maria Concetta De Pinto, Chris Gehring, Candida Vannini. Quantitative phosphoproteomics reveals novel roles of cAMP in plants. Proteomics. 2023 Aug; 23(15):e2300165. doi: 10.1002/pmic.202300165. [PMID: 37264754]
  • Citlaly Gutiérrez-Rodelo, Shirlley Elizabeth Martínez-Tolibia, Guadalupe Elide Morales-Figueroa, Josué Arturo Velázquez-Moyado, J Alberto Olivares-Reyes, Andrés Navarrete-Castro. Modulating cyclic nucleotides pathways by bioactive compounds in combatting anxiety and depression disorders. Molecular biology reports. 2023 Jul; ?(?):. doi: 10.1007/s11033-023-08650-8. [PMID: 37486442]
  • Linlin Qi, Jiří Friml. Tale of cAMP as a second messenger in auxin signaling and beyond. The New phytologist. 2023 Jul; ?(?):. doi: 10.1111/nph.19123. [PMID: 37434303]
  • Brygida Świeżawska-Boniecka, Adriana Szmidt-Jaworska. Phytohormones and cyclic nucleotides - Long-awaited couples?. Journal of plant physiology. 2023 07; 286(?):154005. doi: 10.1016/j.jplph.2023.154005. [PMID: 37186984]
  • Sasanka Ramanadham, John Turk, Sushant Bhatnagar. Noncanonical Regulation of cAMP-Dependent Insulin Secretion and Its Implications in Type 2 Diabetes. Comprehensive Physiology. 2023 06; 13(3):5023-5049. doi: 10.1002/cphy.c220031. [PMID: 37358504]
  • Maura Greiser, Mariusz Karbowski, Aaron David Kaplan, Andrew Kyle Coleman, Nicolas Verhoeven, Carmen A Mannella, W Jonathan Lederer, Liron Boyman. Calcium and bicarbonate signaling pathways have pivotal, resonating roles in matching ATP production to demand. eLife. 2023 Jun; 12(?):. doi: 10.7554/elife.84204. [PMID: 37272417]
  • Havva Afshari, Shokoofe Noori, Afshin Zarghi. A novel combination of metformin and resveratrol alleviates hepatic steatosis by activating autophagy through the cAMP/AMPK/SIRT1 signaling pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2023 May; ?(?):. doi: 10.1007/s00210-023-02520-7. [PMID: 37209153]
  • Jakob Andersson, David Kleinheinz, Ulrich Ramach, Nikolaus Kiesenhofer, Alex Ashenden, Markus Valtiner, Stephen Holt, Ingo Koeper, Philipp A M Schmidpeter, Wolfgang Knoll. Native Function of the Bacterial Ion Channel SthK in a Sparsely Tethered Lipid Bilayer Membrane Architecture. The journal of physical chemistry. B. 2023 04; 127(16):3641-3650. doi: 10.1021/acs.jpcb.2c07252. [PMID: 37072125]
  • Yangyun Wang, Chaoliang Shi, Wandong Yu, Wei Jiao, Guowei Shi. Efficacy of Yougui pill combined with Buzhong Yiqi decoction in alleviating the sexual dysfunction in female rats through modulation of the gut microbiota. Pharmaceutical biology. 2022 Dec; 60(1):46-55. doi: 10.1080/13880209.2021.2010774. [PMID: 34904911]
  • Deng Zang, Chao Niu, Xueying Lu, Haji Akber Aisa. A Novel Furocoumarin Derivative, 5-((diethylamino)me-13 thyl)-3-phenyl-7H-furo [3,2-g] chromen-7-one Upregulates Melanin Synthesis via the Activation of cAMP/PKA and MAPKs Signal Pathway: In Vitro and In Vivo Study. International journal of molecular sciences. 2022 Nov; 23(22):. doi: 10.3390/ijms232214190. [PMID: 36430668]
  • Linlin Qi, Mateusz Kwiatkowski, Huihuang Chen, Lukas Hoermayer, Scott Sinclair, Minxia Zou, Charo I Del Genio, Martin F Kubeš, Richard Napier, Krzysztof Jaworski, Jiří Friml. Adenylate cyclase activity of TIR1/AFB auxin receptors in plants. Nature. 2022 11; 611(7934):133-138. doi: 10.1038/s41586-022-05369-7. [PMID: 36289340]
  • Yuwei Liu, Shen Shen, Zhimin Hao, Qing Wang, Yumei Zhang, Yulan Zhao, Yameng Tong, Fanli Zeng, Jingao Dong. Protein kinase A participates in hyphal and appressorial development by targeting Efg1-mediated transcription of a Rab GTPase in Setosphaeria turcica. Molecular plant pathology. 2022 11; 23(11):1608-1619. doi: 10.1111/mpp.13253. [PMID: 35929228]
  • Naoki Matsumoto, Nalin Singh, Kin Sing Lee, Bogdan Barnych, Christophe Morisseau, Bruce D Hammock. The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms. Prostaglandins & other lipid mediators. 2022 10; 162(?):106662. doi: 10.1016/j.prostaglandins.2022.106662. [PMID: 35779854]
  • Yue DU, Zhi-Wang Wang, Jian-Hong Xi, Ji-Yang Li, Ke-Ke Liang, Ke-Ting Huang, Hui-Ying Luo. [Effects of Angelicae Sinensis Radix on cAMP/Epac signaling pathway in the treatment of chronically infected cough mice with Yin deficiency syndrome]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 2022 Sep; 38(5):475-479. doi: 10.12047/j.cjap.6296.2022.089. [PMID: 37088755]
  • Mingqian Li, Fei Li, Jiabin Chen, He Su, Guanping Chen, Jili Cao, Jiacheng Li, Liyao Dong, Zhihong Yu, Yifan Wang, Chun Zhou, Yongqiang Zhu, Qin Wei, Qun Li, Kequn Chai. Mechanistic insights on cytotoxicity of KOLR, Cinnamomum pauciflorum Nees leaf derived active ingredient, by targeting signaling complexes of phosphodiesterase 3B and rap guanine nucleotide exchange factor 3. Phytotherapy research : PTR. 2022 Sep; 36(9):3540-3554. doi: 10.1002/ptr.7521. [PMID: 35703011]
  • Adilson Guilherme, Leslie A Rowland, Hui Wang, Michael P Czech. The adipocyte supersystem of insulin and cAMP signaling. Trends in cell biology. 2022 Aug; ?(?):. doi: 10.1016/j.tcb.2022.07.009. [PMID: 35989245]
  • Kota Kakeshita, Tsutomu Koike, Teruhiko Imamura, Hayato Fujioka, Hidenori Yamazaki, Koichiro Kinugawa. Altered arginine vasopressin-cyclic AMP-aquaporin 2 pathway in patients with chronic kidney disease. Clinical and experimental nephrology. 2022 Aug; 26(8):788-796. doi: 10.1007/s10157-022-02220-1. [PMID: 35503490]
  • Jingjing Cao, Rendong Zheng, Xiaoyan Chang, Yuanyuan Zhao, Dongjian Zhang, Meng Gao, Zhiqi Yin, Cuihua Jiang, Jian Zhang. Cyclocarya paliurus triterpenoids suppress hepatic gluconeogenesis via AMPK-mediated cAMP/PKA/CREB pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Jul; 102(?):154175. doi: 10.1016/j.phymed.2022.154175. [PMID: 35609386]
  • Xudong Cao, Peng Wang, Haoxing Yuan, Haoran Zhang, Yan He, Kequan Fu, Qian Fang, Hongli Liu, Limin Su, Long Yin, Pei Xu, Yuyang Xie, Xiaochun Xiong, Junqi Wang, Xu Zhu, Dong Guo. Benzodiazepine Derivatives as Potent Vasopressin V2 Receptor Antagonists for the Treatment of Autosomal Dominant Kidney Disease. Journal of medicinal chemistry. 2022 Jul; 65(13):9295-9311. doi: 10.1021/acs.jmedchem.2c00567. [PMID: 35579344]
  • Qi Lai, Yanhua Ma, Jin Bai, Min Zhuang, Shaofei Pei, Ni He, Junlin Yin, Baomin Fan, Zhaoxiang Bian, Guangzhi Zeng, Chengyuan Lin. Mechanisms for Bile Acids CDCA- and DCA-Stimulated Hepatic Spexin Expression. Cells. 2022 07; 11(14):. doi: 10.3390/cells11142159. [PMID: 35883602]
  • María M Adeva-Andany, Carlos Fernández-Fernández, Natalia Carneiro-Freire, Elvira Castro-Quintela, Matilde Vila-Altesor, Manuel González-Lucán. Cardiovascular Protection Associated With Cilostazol, Colchicine, and Target of Rapamycin Inhibitors. Journal of cardiovascular pharmacology. 2022 07; 80(1):31-43. doi: 10.1097/fjc.0000000000001276. [PMID: 35384911]
  • Guilherme Ruiz Leonardi, Caroline Honaiser Lescano, Jose Luiz Costa, Bruna Mazetto, Fernanda Andrade Orsi, Fabiola Zakia Monica. Adenosine diphosphate-induced aggregation is enhanced in platelets obtained from patients with thrombotic primary antiphospholipid syndrome (t-PAPS): Role of P2Y12 -cAMP signaling pathway. Journal of thrombosis and haemostasis : JTH. 2022 07; 20(7):1699-1711. doi: 10.1111/jth.15724. [PMID: 35395698]
  • Zixuan Wang, Xinyuan Wei, Caili Ji, Wenhua Yu, Chuanwang Song, Caizhi Wang. PGE2 inhibits neutrophil phagocytosis through the EP2R-cAMP-PTEN pathway. Immunity, inflammation and disease. 2022 07; 10(7):e662. doi: 10.1002/iid3.662. [PMID: 35759236]
  • Dongli Yu, Wen Song, Eddie Yong Jun Tan, Li Liu, Yu Cao, Jan Jirschitzka, Ertong Li, Elke Logemann, Chenrui Xu, Shijia Huang, Aolin Jia, Xiaoyu Chang, Zhifu Han, Bin Wu, Paul Schulze-Lefert, Jijie Chai. TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death. Cell. 2022 06; 185(13):2370-2386.e18. doi: 10.1016/j.cell.2022.04.032. [PMID: 35597242]
  • Sofia Brito, Jin-Myoung Baek, Byungsun Cha, Hyojin Heo, Su-Hyun Lee, Lei Lei, So Young Jung, So Min Lee, Sang Hun Lee, Byeong-Mun Kwak, Sehyun Chae, Mi-Gi Lee, Bum-Ho Bin. Nicotinamide mononucleotide reduces melanin production in aged melanocytes by inhibiting cAMP/Wnt signaling. Journal of dermatological science. 2022 Jun; 106(3):159-169. doi: 10.1016/j.jdermsci.2022.05.002. [PMID: 35610161]
  • Baijin Chang, Yanru Liu, Jingting Hu, Zhishu Tang, Zhidong Qiu, Zhongxing Song, Ailing Jia, Yuru Zhang. Bupleurum chinense DC improves CUMS-induced depressive symptoms in rats through upregulation of the cAMP/PKA/CREB signalling pathway. Journal of ethnopharmacology. 2022 May; 289(?):115034. doi: 10.1016/j.jep.2022.115034. [PMID: 35092825]
  • Robert L Rodgers. Glucagon, cyclic AMP, and hepatic glucose mobilization: A half-century of uncertainty. Physiological reports. 2022 05; 10(9):e15263. doi: 10.14814/phy2.15263. [PMID: 35569125]
  • Maria F Fernandes, Michelle V Tomczewski, Robin E Duncan. Glucagon-like Peptide-1 Secretion Is Inhibited by Lysophosphatidic Acid. International journal of molecular sciences. 2022 Apr; 23(8):. doi: 10.3390/ijms23084163. [PMID: 35456981]
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