Reserpine (BioDeep_00000397995)

Main id: BioDeep_00000000255

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


NCGC00091250-14_C33H40N2O9_Serpalan

化学式: C33H40N2O9 (608.2734)
中文名称: 利血平
谱图信息: 最多检出来源 Homo sapiens(blood) 19.96%

分子结构信息

SMILES: c(C6([H])[H])(c12)c(C(N(C6([H])[H])5)(C(C([H])(C([H])3C(=O)OC([H])([H])[H])C([H])(C5([H])[H])C(C(OC(=O)c(c4[H])c(c(OC([H])([H])[H])c(c(OC([H])([H])[H])4)OC([H])([H])[H])[H])([H])C3(OC([H])([H])[H])[H])([H])[H])([H])[H])[H])n(c1c([H])c(c(c([H])2)[H])OC([H])([H])[H])[H]
InChI: InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1

描述信息

CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3638; ORIGINAL_PRECURSOR_SCAN_NO 3636
C - Cardiovascular system > C02 - Antihypertensives > C02A - Antiadrenergic agents, centrally acting > C02AA - Rauwolfia alkaloids
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents
D049990 - Membrane Transport Modulators
C1744 - Multidrug Resistance Modulator
CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3640; ORIGINAL_PRECURSOR_SCAN_NO 3636
CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7960; ORIGINAL_PRECURSOR_SCAN_NO 7956
CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7956; ORIGINAL_PRECURSOR_SCAN_NO 7955
CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7956; ORIGINAL_PRECURSOR_SCAN_NO 7953
CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7990; ORIGINAL_PRECURSOR_SCAN_NO 7988
CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7985; ORIGINAL_PRECURSOR_SCAN_NO 7982
CONFIDENCE standard compound; INTERNAL_ID 1013; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7983; ORIGINAL_PRECURSOR_SCAN_NO 7980
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2263
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.022
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.021
Acquisition and generation of the data is financially supported by the Max-Planck-Society
IPB_RECORD: 2261; CONFIDENCE confident structure
Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).

同义名列表

4 个代谢物同义名

Reserpine; (-)-Reserpine; NCGC00091250-14_C33H40N2O9_Serpalan; Reserpine



数据库引用编号

77 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

62 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 BDNF, DDC, POMC, PRL, SLC6A3, SNCA
Endoplasmic reticulum membrane 1 DRD1
Nucleus 4 DRD1, FOS, PRL, SNCA
cytosol 3 DDC, FOS, SNCA
dendrite 5 BDNF, DRD2, HTR1A, MAOB, SLC18A2
centrosome 1 SLC18A2
nucleoplasm 3 ATP2B1, FOS, PRL
RNA polymerase II transcription regulator complex 2 FOS, PRL
Cell membrane 7 ADRB3, ATP2B1, DRD1, DRD2, HTR1A, SLC6A3, TNF
Cytoplasmic side 1 MAOB
Cell projection, axon 3 SLC18A2, SLC6A3, SNCA
Multi-pass membrane protein 8 ADRB3, ATP2B1, CACNA1I, DRD1, DRD2, HTR1A, SLC18A2, SLC6A3
Golgi apparatus membrane 1 DRD2
Synapse 5 ATP2B1, CRH, DRD2, HTR1A, SNCA
cell cortex 1 SNCA
cell surface 2 SLC6A3, TNF
glutamatergic synapse 3 ATP2B1, DRD1, DRD2
Golgi apparatus 1 QSOX1
Golgi membrane 3 DRD2, INS, QSOX1
growth cone 1 SNCA
neuronal cell body 4 MAOB, SLC6A3, SNCA, TNF
postsynapse 1 SNCA
presynaptic membrane 4 ATP2B1, DRD1, DRD2, SLC6A3
synaptic vesicle 2 BDNF, SLC18A2
Lysosome 1 SNCA
acrosomal vesicle 1 DRD2
plasma membrane 11 ADRB3, ATP2B1, BCHE, CACNA1I, DRD1, DRD2, HTR1A, SLC18A2, SLC6A3, SNCA, TNF
synaptic vesicle membrane 4 ATP2B1, DRD2, SLC18A2, SNCA
terminal bouton 1 SLC18A2
Membrane 6 ATP2B1, BDNF, CACNA1I, SLC18A2, SLC6A3, SNCA
axon 5 BDNF, DRD2, SLC18A2, SLC6A3, SNCA
basolateral plasma membrane 1 ATP2B1
extracellular exosome 3 ATP2B1, DDC, QSOX1
endoplasmic reticulum 1 FOS
extracellular space 9 BCHE, BDNF, CRH, INS, POMC, PRL, QSOX1, SNCA, TNF
perinuclear region of cytoplasm 2 BDNF, SNCA
mitochondrion 2 MAOB, SNCA
protein-containing complex 1 SNCA
intracellular membrane-bounded organelle 3 ATP2B1, QSOX1, SLC18A2
Secreted 8 BCHE, BDNF, CRH, INS, POMC, PRL, QSOX1, SNCA
extracellular region 9 BCHE, BDNF, CRH, INS, POMC, PRL, QSOX1, SNCA, TNF
Mitochondrion outer membrane 1 MAOB
Single-pass membrane protein 1 QSOX1
mitochondrial outer membrane 1 MAOB
neuronal cell body membrane 1 SLC6A3
[Isoform 2]: Secreted 1 QSOX1
ciliary membrane 2 DRD1, DRD2
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 2 ATP2B1, SLC18A2
external side of plasma membrane 1 TNF
varicosity 1 CRH
actin cytoskeleton 1 SNCA
dendritic spine 2 DRD1, DRD2
neuronal dense core vesicle lumen 1 CRH
perikaryon 2 CRH, DRD2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 3 DRD1, DRD2, SLC6A3
Membrane raft 2 SLC6A3, TNF
GABA-ergic synapse 2 DRD1, DRD2
flotillin complex 1 SLC6A3
Cell projection, dendritic spine 1 DRD1
secretory granule 1 POMC
lateral plasma membrane 2 ATP2B1, DRD2
receptor complex 1 ADRB3
Cell projection, neuron projection 1 SLC6A3
neuron projection 1 SLC6A3
cilium 2 DRD1, DRD2
chromatin 2 FOS, PRL
cell projection 1 ATP2B1
phagocytic cup 1 TNF
supramolecular fiber 1 SNCA
blood microparticle 1 BCHE
non-motile cilium 2 DRD1, DRD2
Basolateral cell membrane 1 ATP2B1
intercellular bridge 1 QSOX1
sperm flagellum 1 DRD2
endosome lumen 2 INS, PRL
Cell projection, dendrite 3 DRD1, HTR1A, SLC18A2
Presynaptic cell membrane 1 ATP2B1
secretory granule lumen 2 INS, POMC
secretory granule membrane 1 SLC18A2
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 BCHE, BDNF, INS, QSOX1
nuclear matrix 1 FOS
platelet alpha granule lumen 1 QSOX1
axon terminus 3 DRD2, SLC6A3, SNCA
voltage-gated calcium channel complex 1 CACNA1I
[Isoform 1]: Golgi apparatus membrane 1 QSOX1
specific granule lumen 1 QSOX1
tertiary granule lumen 1 QSOX1
endocytic vesicle 1 DRD2
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
mitochondrial envelope 1 MAOB
immunological synapse 1 ATP2B1
Single-pass type IV membrane protein 1 MAOB
nuclear envelope lumen 1 BCHE
protein-DNA complex 1 FOS
dopaminergic synapse 3 DRD2, SLC18A2, SLC6A3
Cytoplasmic vesicle, secretory vesicle membrane 1 SLC18A2
Cell projection, cilium membrane 1 DRD1
transcription factor AP-1 complex 1 FOS
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
inclusion body 1 SNCA
photoreceptor ribbon synapse 1 ATP2B1
G protein-coupled receptor complex 2 DRD1, DRD2
clathrin-sculpted monoamine transport vesicle membrane 1 SLC18A2
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Riccardo Lorrai, Dario Cavaterra, Sara Giammaria, Diego Sbardella, Grazia Raffaella Tundo, Alessandra Boccaccini. Eye Diseases: When the Solution Comes from Plant Alkaloids. Planta medica. 2024 May; 90(6):426-439. doi: 10.1055/a-2283-2350. [PMID: 38452806]
  • Julia G Odnoshivkina, Guzel V Sibgatullina, Alexey M Petrov. Lipid-dependent regulation of neurotransmitter release from sympathetic nerve endings in mice atria. Biochimica et biophysica acta. Biomembranes. 2023 10; 1865(7):184197. doi: 10.1016/j.bbamem.2023.184197. [PMID: 37394027]
  • Johané Gericke, Brian H Harvey, Lesha Pretorius, Tracey Ollewagen, Rohan M Benecke, Carine Smith. Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents. Journal of ethnopharmacology. 2023 Sep; 319(Pt 1):117113. doi: 10.1016/j.jep.2023.117113. [PMID: 37660956]
  • Xuan Zhang, Ci Wang, Ze-Yu Zhang, Pei-Pei Zhang, Qiu'an Ren, Xian-Liang Wang, Jing-Yuan Mao. [Establishment of a Rat Model of Hypotension Induced by Reserpine]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2023 Aug; 45(4):533-540. doi: 10.3881/j.issn.1000-503x.15376. [PMID: 37654133]
  • Himanshi Swain, Saikat Gantait, Nirmal Mandal. Developments in biotechnological tools and techniques for production of reserpine. Applied microbiology and biotechnology. 2023 May; ?(?):. doi: 10.1007/s00253-023-12570-9. [PMID: 37212883]
  • Massimo Marano. Reserpine induced parkinsonism, a hidden threat of herbal medicine. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023 04; 44(4):1425-1427. doi: 10.1007/s10072-022-06578-8. [PMID: 36571640]
  • Marcus Daniel Brandbjerg Bohn Lorensen, Nanna Bjarnholt, Benoit St-Pierre, Vincent Courdavault, Sarah Heinicke, Sarah O'Connor, Christian Janfelt. Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging. Phytochemistry. 2023 Feb; ?(?):113620. doi: 10.1016/j.phytochem.2023.113620. [PMID: 36863602]
  • Fauziahanim Zakaria, Muhammad Tayyab Akhtar, Wan Ibrahim Wan Norhamidah, Abu Bakar Noraini, Azira Muhamad, Shamarina Shohaimi, Maulidiani, Hafandi Ahmad, Intan Safinar Ismail, Nor Hadiani Ismail, Khozirah Shaari. Centella asiatica (L.) Urb. Extract ameliorates branched-chain amino acid (BCAA) metabolism in acute reserpine-induced stress zebrafish model via 1H Nuclear Magnetic Resonance (NMR)-based metabolomics approach. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023 Feb; 264(?):109501. doi: 10.1016/j.cbpc.2022.109501. [PMID: 36336330]
  • Junhui He, Dongmei Li, Jie Wei, Sheng Wang, Shifeng Chu, Zhao Zhang, Fei He, Dongmei Wei, Yi Li, Jiaxiu Xie, Kedao Lai, Naihong Chen, Guining Wei. Mahonia Alkaloids (MA) Ameliorate Depression Induced Gap Junction Dysfunction by miR-205/Cx43 Axis. Neurochemical research. 2022 Dec; 47(12):3761-3776. doi: 10.1007/s11064-022-03761-3. [PMID: 36222958]
  • Samaresh Pal Roy, Sunil Kumar Kadiri, Vipulkumar V Karkar, Srinivasa Rao Konijeti. Antiparkinsonian activity of Tabebuia impetiginosa bark and biochemical analysis of dopamine in rat brain homogenates. Annales pharmaceutiques francaises. 2022 Nov; 80(6):853-863. doi: 10.1016/j.pharma.2022.02.007. [PMID: 35240121]
  • Eduarda Gomes Ferrarini, Rodrigo Sebben Paes, Gabriela Mantovani Baldasso, Pollyana Mendonça de Assis, Murilo Chaves Gouvêa, Paola De Cicco, Nádia Rezende Barbosa Raposo, Raffaele Capasso, Eduardo Luiz Gasnhar Moreira, Rafael Cypriano Dutra. Broad-spectrum cannabis oil ameliorates reserpine-induced fibromyalgia model in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Oct; 154(?):113552. doi: 10.1016/j.biopha.2022.113552. [PMID: 35988425]
  • Jose Ivo A Beserra-Filho, Amanda Maria-Macêdo, Suellen Silva-Martins, Ana Cláudia Custódio-Silva, Beatriz Soares-Silva, Sara Pereira Silva, Rafael Herling Lambertucci, Adriano Antunes de Souza Araújo, Angélica Maria Lucchese, Lucindo J Quintans-Júnior, José Ronaldo Santos, Regina H Silva, Alessandra M Ribeiro. Lippia grata essential oil complexed with β-cyclodextrin ameliorates biochemical and behavioral deficits in an animal model of progressive parkinsonism. Metabolic brain disease. 2022 10; 37(7):2331-2347. doi: 10.1007/s11011-022-01032-2. [PMID: 35779151]
  • Asmaa M Zaazaa, Nadia N Daoud, Ola A El-Gendy, Ahmad I Al-Shafei. Neuroprotective role of Bacopa monnieri extract in modulating depression in an experimental rat model. Journal of affective disorders. 2022 07; 308(?):229-235. doi: 10.1016/j.jad.2022.04.021. [PMID: 35413358]
  • Jingjie Zhao, Wei Shi, Yujia Lu, Xuesong Gao, Anna Wang, Shan Zhang, Yi Du, Yongzhi Wang, Li Li. Alterations of monoamine neurotransmitters, HPA-axis hormones, and inflammation cytokines in reserpine-induced hyperalgesia and depression comorbidity rat model. BMC psychiatry. 2022 06; 22(1):419. doi: 10.1186/s12888-022-04065-0. [PMID: 35733107]
  • Sedighe Talebi, Batool Rahmati, Masoumeh Jorjani, Fatemeh Emadi, Farzaneh Ghaffari, Mohsen Naseri. Synergistic effects of Nepeta menthoides and Melissa officinalis aqueous extracts on reserpine-induced depressive-like behaviors in mice. Phytotherapy research : PTR. 2022 Jun; 36(6):2481-2494. doi: 10.1002/ptr.7457. [PMID: 35470926]
  • Shvetank Bhatt, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Sridevi Chigurupati, Amira Saber Ahmed, Sreelakshmi Bada V Gari. Investigation of Cochlospermum religiosum leaves for antidepressant and anxiolytic activities and its synergistic effect with imipramine and fluoxetine. Environmental science and pollution research international. 2022 Apr; 29(18):27172-27181. doi: 10.1007/s11356-021-18359-5. [PMID: 34981394]
  • Nikhitha Lakshmi, Ameer Basha Shaik, Pragya Paramita Pal, Sajeli Begum Ahil, Ramya Vittal, Saida Naik, Uma Devi Gali, Vidya Sagar Bokka. Piperine, Reserpine and β-Sitosterol Attenuate Stem Rot (Sclerotium rolfsii Sacc.) of Groundnut by Inducing the Secretion of defense Enzymes and Phenolic Acids. Chemistry & biodiversity. 2022 Apr; 19(4):e202100880. doi: 10.1002/cbdv.202100880. [PMID: 35182415]
  • Nianyun Yang, Lisi Zou, Ye Wang. Label-free quantitative proteomic analysis of reserpine-induced depression in mice intervened by berberine. Pakistan journal of pharmaceutical sciences. 2022 Jan; 35(1):151-155. doi: ". [PMID: 35221284]
  • Noreen Samad, Natasha Manzoor, Zahra Muneer, Sheraz A Bhatti, Imran Imran. Reserpine-induced altered neuro-behavioral, biochemical and histopathological assessments prevent by enhanced antioxidant defence system of thymoquinone in mice. Metabolic brain disease. 2021 12; 36(8):2535-2552. doi: 10.1007/s11011-021-00789-2. [PMID: 34309746]
  • Suellen Silva-Martins, Jose Ivo Araújo Beserra-Filho, Amanda Maria-Macêdo, Ana Cláudia Custódio-Silva, Beatriz Soares-Silva, Sara Pereira Silva, Rafael Herling Lambertucci, Regina Helena Silva, José Ronaldo Dos Santos, Sathiyabama Rajiv Gandhi, Lucindo José Quintans-Júnior, Alessandra Mussi Ribeiro. Myrtenol complexed with β-cyclodextrin ameliorates behavioural deficits and reduces oxidative stress in the reserpine-induced animal model of Parkinsonism. Clinical and experimental pharmacology & physiology. 2021 11; 48(11):1488-1499. doi: 10.1111/1440-1681.13563. [PMID: 34351001]
  • Anderson H F F Leão, Ywlliane S R Meurer, Thalma A Freitas, André M Medeiros, Vanessa C Abílio, Geison S Izídio, Isaltino M Conceição, Alessandra M Ribeiro, Regina H Silva. Changes in the mesocorticolimbic pathway after low dose reserpine-treatment in Wistar and Spontaneously Hypertensive Rats (SHR): Implications for cognitive deficits in a progressive animal model for Parkinson's disease. Behavioural brain research. 2021 07; 410(?):113349. doi: 10.1016/j.bbr.2021.113349. [PMID: 33971246]
  • Muhammad Afiq Ngadni, Muhammad Tayyab Akhtar, Intan Safinar Ismail, Anis Irfan Norazhar, Soo Yee Lee, Maulidiani Maulidiani, Khozirah Shaari. Clitorienolactones and Isoflavonoids of Clitorea ternatea Roots Alleviate Stress-Like Symptoms in a Reserpine-Induced Zebrafish Model. Molecules (Basel, Switzerland). 2021 Jul; 26(14):. doi: 10.3390/molecules26144137. [PMID: 34299411]
  • Noreen Samad, Saima Khaliq, Mehtab Alam, Farzana Yasmin, Saara Ahmad, Sana Mustafa, - Azizuddin, Uzma Raza. Tryptophan lessens reserpine induced anxiety, depression and memory impairment by modulating oxidative stress and serotonergic activity. Pakistan journal of pharmaceutical sciences. 2021 Jul; 34(4(Supplementary)):1499-1508. doi: ". [PMID: 34799325]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Zhen Peng, Ji-Xing Liu, Hui Zhu, Teng Guo, Li Xu, Jun-Guo Dong, Ping Cheng, Zhen Zhou. Development of a new atmospheric pressure plasmaspray ionization for ambient mass spectrometry. Journal of mass spectrometry : JMS. 2021 Apr; 56(4):e4629. doi: 10.1002/jms.4629. [PMID: 32767454]
  • Adeleke Opeyemi, Oyewopo Adeoye, Akingbade Adebanji, Johnson Olawumi. CREM, PRM I and II gene expression in Wistar rats testes treated with antipsychotic drugs: Chlorpromazine, Rauwolfia vomitoria and co-administration of reserpine, zinc and ascorbic acid. JBRA assisted reproduction. 2021 02; 25(1):97-103. doi: 10.5935/1518-0557.20200058. [PMID: 32960520]
  • Anudeep Kaur, Lovedeep Singh, Saweta Garg, Harmanpreet Kaur, Nirmal Singh, Rajbir Bhatti. Involvement of Oxidative Stress and Nerve Growth Factor in Behavioral and Biochemical Deficits of Experimentally Induced Musculoskeletal Pain in Mice: Ameliorative Effects of Heraclin. Journal of molecular neuroscience : MN. 2021 Feb; 71(2):347-357. doi: 10.1007/s12031-020-01656-y. [PMID: 32676972]
  • Enas Mahmoud Moustafa, Engy Refaat Rashed, Rasha Refaat Rashed, Nesreen Nabil Omar. Piceatannol promotes hepatic and renal AMPK/SIRT1/PGC-1α mitochondrial pathway in rats exposed to reserpine or gamma-radiation. International journal of immunopathology and pharmacology. 2021 Jan; 35(?):20587384211016194. doi: 10.1177/20587384211016194. [PMID: 33985371]
  • Namrta Choudhry, Xin Zhao, Dan Xu, Mark Zanin, Weisan Chen, Zifeng Yang, Jianxin Chen. Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Journal of medicinal chemistry. 2020 11; 63(22):13205-13227. doi: 10.1021/acs.jmedchem.0c00626. [PMID: 32845145]
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