Clarithromycin (BioDeep_00000397468)

Main id: BioDeep_00000002154

 

natural product


代谢物信息卡片


(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dion

化学式: C38H69NO13 (747.4768664)
中文名称: (14R)-14-羟基克拉霉素, 克拉霉素
谱图信息: 最多检出来源 Homo sapiens(urine) 94.34%

分子结构信息

SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O
InChI: InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

描述信息

The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01F - Macrolides, lincosamides and streptogramins > J01FA - Macrolides
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065692 - Cytochrome P-450 CYP3A Inhibitors
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Origin: Microbe
CONFIDENCE standard compound; INTERNAL_ID 1053
CONFIDENCE standard compound; INTERNAL_ID 4085

同义名列表

4 个代谢物同义名

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dion; Clarithromycin; "Clarithromycin (Biaxin, Klacid)"; Clarithromycin



数据库引用编号

45 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Kiarash Ghazvini, Hossein Kamali, Hadi Farsiani, Masoud Yousefi, Masoud Keikha. Sustain-release lipid-liquid crystal formulations of pexiganan against Helicobacter pylori infection: in vitro evaluation in C57BL/6 mice. BMC pharmacology & toxicology. 2024 01; 25(1):9. doi: 10.1186/s40360-024-00731-z. [PMID: 38212864]
  • Variya Nemidkanam, Wijit Banlunara, Nuntaree Chaichanawongsaroj. Kaempferia parviflora Extracellular Vesicle Loaded with Clarithromycin for the Treatment of Helicobacter pylori Infection. International journal of nanomedicine. 2024; 19(?):1967-1983. doi: 10.2147/ijn.s444686. [PMID: 38435753]
  • Ying-Ying Han, Lin Zhou, Yun-Lian Hu, Xiang-Wu Ding, Hui Long, Fei Liu, Ming Xu, Zhen-Yu Zhang, Shuang-Ling Li, Qiu-Yan Wang, Cheng-Xia Su, Yan Chen, Jie Chen, Ya Lin, Pei-Yuan Li. Comparison of vonoprazan-based with rabeprazole-based dual therapy for treatment-naive patients of Helicobacter pylori infection: a prospective, multi-center, randomized controlled study. Journal of gastroenterology. 2023 Oct; ?(?):. doi: 10.1007/s00535-023-02042-2. [PMID: 37777987]
  • Lucía Rodríguez-López, Vanesa Santás-Miguel, Raquel Cela-Dablanca, Avelino Núñez-Delgado, Esperanza Álvarez-Rodríguez, Andrés Rodríguez-Seijo, Manuel Arias-Estévez. Clarithromycin as soil and environmental pollutant: Adsorption-desorption processes and influence of pH. Environmental research. 2023 09; 233(?):116520. doi: 10.1016/j.envres.2023.116520. [PMID: 37390951]
  • Yuxiang Wang, Jinran Du, Dayan Zhang, Cong Jin, Jiangpo Chen, Zeyuan Wang, Tonglin Mei, Kaili Fu, Qingzeng Qian, Tieliang Pang. Primary antibiotic resistance in Helicobacter pylori in China: a systematic review and meta-analysis. Journal of global antimicrobial resistance. 2023 09; 34(?):30-38. doi: 10.1016/j.jgar.2023.05.014. [PMID: 37315738]
  • Shasha Chen, Weina Shen, Yuhuan Liu, Qiang Dong, Yongquan Shi. Efficacy and safety of triple therapy containing berberine, amoxicillin, and vonoprazan for Helicobacter pylori initial treatment: A randomized controlled trial. Chinese medical journal. 2023 Jul; 136(14):1690-1698. doi: 10.1097/cm9.0000000000002696. [PMID: 37469024]
  • J M Castaño-Ortiz, R Gil-Solsona, N Ospina-Alvarez, M M García-Pimentel, V M León, L H M L M Santos, D Barceló, S Rodríguez-Mozaz. Bioaccumulation and fate of pharmaceuticals in a Mediterranean coastal lagoon: Temporal variation and impact of a flash flood event. Environmental research. 2023 07; 228(?):115887. doi: 10.1016/j.envres.2023.115887. [PMID: 37054836]
  • Shengjuan Hu, Yan Zhou, Yanhong Deng, Yang Bo, Xianmei Chen, Wei Yang, Ruichun Shi, Wei Zhao, Zhanbing Hou, Jianping Hu, Jianguo Liu, Xilong Zhang, Heli Yong, Ping Wang, Fei Li, Hailong Qi, Xiaoyun Wang, Lijuan Jin, Ting Cui, Haijiang Yong, Xue Li, Bin Yang, Yuehua Yu, Bin Ma, Lei Fu, Xuemei Wang, Zhen Ma, Na Tang, Yanjie You, Jianyang Guo, Xiaobing Yu, Li Yao, Ruiping Gao, Yanling Li, Ruijuan Xin, Jianfang Liu, Zhenzi Cao, Hongliang Li, Linke Ma, Shoucheng Ma, Ying Cao, Yuanyuan Tang, Jun Liu, Qian Hao, Xiaofei Li, Xuemei Li, Rui Mu, Min Niu, Xiaoming Su, Hengjun Gao. Characteristics of phenotypic antibiotic resistance of Helicobacter pylori and its correlation with genotypic antibiotic resistance: A retrospective study in Ningxia. Helicobacter. 2023 Jun; 28(3):e12960. doi: 10.1111/hel.12960. [PMID: 37042045]
  • Bahar Ikizoglu, Fatma Ilter Turkdogan, Gurdal Kanat, Coskun Aydiner. Seasonal analysis of commonly prescribed antibiotics in Istanbul city. Environmental monitoring and assessment. 2023 Apr; 195(5):566. doi: 10.1007/s10661-023-11203-y. [PMID: 37058249]
  • Xueping Huang, Baihe Wu, Qiuzhao Chen, Yushan Chen, Xinhua Ji, Xiang Zhou, Biao Suo, Zhihui Lin, Xiaoling Zheng. Antibiotic resistance profile of Helicobacter pylori to 14 antibiotics: a multicenter study in Fujian, China. PeerJ. 2023; 11(?):e15611. doi: 10.7717/peerj.15611. [PMID: 37456872]
  • Aiman A Shoiab, Ali Alsarhan, Ashraf O Khashroum. EFFECT OF PHARMACIST COUNSELING ON PATIENT MEDICATION COMPLIANCE AND HELICOBACTER PYLORI ERADICATION AMONG JORDANIAN OUTPATIENTS. Arquivos de gastroenterologia. 2023 Jan; 60(1):74-83. doi: 10.1590/s0004-2803.202301000-10. [PMID: 37194783]
  • Haoqi Wang, Nirmitee Mulgaonkar, Samavath Mallawarachchi, Manikandan Ramasamy, Carmen S Padilla, Sonia Irigoyen, Gitta Coaker, Kranthi K Mandadi, Sandun Fernando. Evaluation of Candidatus Liberibacter Asiaticus Efflux Pump Inhibition by Antimicrobial Peptides. Molecules (Basel, Switzerland). 2022 Dec; 27(24):. doi: 10.3390/molecules27248729. [PMID: 36557860]
  • Guoxin Bai, Junyu Yi, Yuanyuan Yu, Hongxing Du. Clinical effect of Anwei Qingyou recipe on peptic ulcer and its effect on the levels of EGF and PGE2: A retrospective study. Medicine. 2022 Oct; 101(40):e30898. doi: 10.1097/md.0000000000030898. [PMID: 36221352]
  • Stella G Michael, Barbara Drigo, Irene Michael-Kordatou, Costas Michael, Thomas Jäger, Samuel C Aleer, Thomas Schwartz, Erica Donner, Despo Fatta-Kassinos. The effect of ultrafiltration process on the fate of antibiotic-related microcontaminants, pathogenic microbes, and toxicity in urban wastewater. Journal of hazardous materials. 2022 08; 435(?):128943. doi: 10.1016/j.jhazmat.2022.128943. [PMID: 35650718]
  • Yuan-Yuan Dai, Chun Qin, Gan-Rong Huang, Yan-Chun Qin, Yong-Yi Huang, Yan-Qiang Huang, Li-Juan Zhao. Linolenic Acid-Metronidazole: a Compound Relieving Drug Resistance and Inhibiting Helicobacter pylori. Antimicrobial agents and chemotherapy. 2022 07; 66(7):e0007322. doi: 10.1128/aac.00073-22. [PMID: 35758720]
  • Eleonora Altman, Vandana Chandan, Blair A Harrison, Melissa Schur, Marie-France Goneau, Jianjun Li, Michel Gilbert. Chemoenzymatic synthesis of an α-1,6-glucan-based conjugate vaccine against Helicobacter pylori. Glycobiology. 2022 Jul; 32(8):691-700. doi: 10.1093/glycob/cwac023. [PMID: 35436341]
  • Timothy Arthur Chandos Snow, Alessia Longobardo, David Brealey, Jim Down, Giovanni Satta, Mervyn Singer, Nishkantha Arulkumaran. Beneficial ex vivo immunomodulatory and clinical effects of clarithromycin in COVID-19. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022 Jul; 28(7):948-954. doi: 10.1016/j.jiac.2022.04.001. [PMID: 35440370]
  • Chen Yang, Sai Li, Taoyang Huang, Hongju Lin, Zhihui Jiang, Yongyang He, Junjie Yuan, Huijie An. Effectiveness and safety of vonoprazan-based regimen for Helicobacter pylori eradication: A meta-analysis of randomized clinical trials. Journal of clinical pharmacy and therapeutics. 2022 Jul; 47(7):897-904. doi: 10.1111/jcpt.13637. [PMID: 35247003]
  • Ryo Yonezawa, Tomiko Sunaga. Signal of safety due to adverse drug reactions induced by tacrolimus with or without azithromycin. Transplant infectious disease : an official journal of the Transplantation Society. 2022 Jun; 24(3):e13833. doi: 10.1111/tid.13833. [PMID: 35385596]
  • Pei-Qian Wu, Yong-Sheng Cui, Xiao-Ying Han, Chen Wang, Pei-Pei An, Jun-Su Zhou, Yu-Hao Ren, Zhen-Long Liu, Rong-Tuan Lin, Bin Zhou, Jian-Min Yue. Diterpenoids from Sauropus spatulifolius Leaves with Antimicrobial Activities. Journal of natural products. 2022 05; 85(5):1304-1314. doi: 10.1021/acs.jnatprod.2c00020. [PMID: 35427111]
  • Eva C Arrua, Sofía V Sanchez, Valeria Trincado, Antonio Hidalgo, Andrew F G Quest, Javier O Morales. Experimental design and optimization of a novel dual-release drug delivery system with therapeutic potential against infection with Helicobacter pylori. Colloids and surfaces. B, Biointerfaces. 2022 May; 213(?):112403. doi: 10.1016/j.colsurfb.2022.112403. [PMID: 35219219]
  • Mingming Xu, Junfei Zhou, Ding Heng, Xiaorong Su, Monday M Onakpa, Yuefan Bai, Jin-Ao Duan, Chun-Tao Che, Hongkai Bi, Ming Zhao. Quinone Derivatives as Promising Anti-Helicobacter pylori Agents from Aerial Parts of Mitracarpus hirtus. Journal of natural products. 2022 04; 85(4):1029-1038. doi: 10.1021/acs.jnatprod.1c01163. [PMID: 35412828]
  • Saranya Poapolathep, Mario Giorgi, Narumol Klangkaew, Kraisiri Khidkhan, Narongsak Chaiyabutr, Tara Wongwaipairoj, Amnart Poapolathep. Pharmacokinetic profiles of clarithromycin in freshwater crocodiles (Crocodylus siamensis). Journal of veterinary pharmacology and therapeutics. 2022 Mar; 45(2):147-152. doi: 10.1111/jvp.13034. [PMID: 34845734]
  • Amna Arshad, Ikram Ullah Khan, Moazam Ali, Fatima Arshad, Adeela Riaz, Zeeshan Ahmad Bhutta, Ambreen Ashar. Probing the Synergistic Effect of Antibacterial Drug and Oleic Acid in Lipid-based Gastroretentive Matrices by Melt Molding Method. Current drug delivery. 2022; 20(1):89-97. doi: 10.2174/1567201819666220412112104. [PMID: 35418284]
  • Ki Young Huh, Hyewon Chung, Yu Kyong Kim, SeungHwan Lee, Siddharth Bhatia, Yohei Takanami, Ryou Nakaya, Kyung-Sang Yu. Evaluation of safety and pharmacokinetics of bismuth-containing quadruple therapy with either vonoprazan or lansoprazole for Helicobacter pylori eradication. British journal of clinical pharmacology. 2022 01; 88(1):138-144. doi: 10.1111/bcp.14934. [PMID: 34080718]
  • Osamu Iketani, Akari Komeya, Yuki Enoki, Kazuaki Taguchi, Shunsuke Uno, Yoshifumi Uwamino, Kazuaki Matsumoto, Junko Kizu, Naoki Hasegawa. Impact of rifampicin on the pharmacokinetics of clarithromycin and 14-hydroxy clarithromycin in patients with multidrug combination therapy for pulmonary Mycobacterium avium complex infection. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022 Jan; 28(1):61-66. doi: 10.1016/j.jiac.2021.10.003. [PMID: 34706852]
  • Yalda Lucero, Anne J Lagomarcino, Juan P Torres, Patricia Roessler, Nora Mamani, Sergio A George, Nicole Huerta, Mónica González, Miguel O'Ryan G. Effect of Helicobacter pylori eradication therapy on clinical and laboratory biomarkers associated with gastric damage in healthy school-aged children: A randomized non-blinded trial. Helicobacter. 2021 Dec; 26(6):e12853. doi: 10.1111/hel.12853. [PMID: 34528337]
  • Ryohei Hirano, Akitomo Yokokawa, Tomomi Furihata, Hiromi Shibasaki. Dried blood spots analysis of 6β-hydroxycortisol and cortisol using liquid chromatography/tandem mass spectrometry for calculating 6β-hydroxycortisol to cortisol ratio. Journal of mass spectrometry : JMS. 2021 Dec; 56(12):e4790. doi: 10.1002/jms.4790. [PMID: 34881490]
  • Sheng Kuang, Jinkang Xu, Miaomiao Chen, Yongliang Zhang, Fangzhen Shi, Xirong Lu. The influence of pretreatment with PPI on Helicobacter pylori eradication: A systematic review and meta-analysis. Medicine. 2021 Nov; 100(47):e27944. doi: 10.1097/md.0000000000027944. [PMID: 34964772]
  • Yinhui Qin, Linlin Xu, Yuetai Teng, Yan Yang, Yinhu Wang, Peizhi Ma. Design, synthesis and antibacterial evaluation of novel 3-O-substituted 15-membered azalides possessing 1,2,3-triazole side chains. Bioorganic & medicinal chemistry letters. 2021 10; 49(?):128330. doi: 10.1016/j.bmcl.2021.128330. [PMID: 34403726]
  • Ken Kurosawa, Stefaan Rossenu, Jeike Biewenga, Sivi Ouwerkerk-Mahadevan, Wouter Willems, Etienne Ernault, Chrispin Kambili. Population Pharmacokinetic Analysis of Bedaquiline-Clarithromycin for Dose Selection Against Pulmonary Nontuberculous Mycobacteria Based on a Phase 1, Randomized, Pharmacokinetic Study. Journal of clinical pharmacology. 2021 10; 61(10):1344-1355. doi: 10.1002/jcph.1887. [PMID: 33991350]
  • Kazuko Yamamoto, Naoki Hosogaya, Noriho Sakamoto, Haruo Yoshida, Hiroshi Ishii, Kazuhiro Yatera, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae. Efficacy of clarithromycin in patients with mild COVID-19 pneumonia not receiving oxygen administration: protocol for an exploratory, multicentre, open-label, randomised controlled trial (CAME COVID-19 study). BMJ open. 2021 09; 11(9):e053325. doi: 10.1136/bmjopen-2021-053325. [PMID: 34548368]
  • N Takemori, H K Ooi, G Imai, M Saio. Diverse effects of clarithromycin and proposal of its clinical application for treating COVID-19 as a repurposing drug. Tropical biomedicine. 2021 Sep; 38(3):343-352. doi: 10.47665/tb.38.3.077. [PMID: 34508342]
  • Allison Kirchner, Artem Sergeyenko, Janice Keane, Kenneth Belinski, Wenhua Liu. Diagnosis of cutaneous mycobacterial spindle cell pseudotumor in the absence of typical inflammatory cells: A case report. Journal of cutaneous pathology. 2021 Sep; 48(9):1178-1181. doi: 10.1111/cup.14042. [PMID: 33948982]
  • Alaa Rashad, Asmaa Nafady, Mohammed H Hassan, Haggagy Mansour, Usama Taya, Shamardan Ezzeldin S Bazeed, Zaki F Aref, Mennatallah Ali Abdelrhman Sayed, Hanaa Nafady-Hego, Aida A Abdelmaksoud. Therapeutic efficacy of macrolides in management of patients with mild COVID-19. Scientific reports. 2021 08; 11(1):16361. doi: 10.1038/s41598-021-95900-z. [PMID: 34381155]
  • M Kovacheva-Slavova, H Valkov, T Angelov, R Tropcheva, B Vladimirov. Screening for Helicobacter pylori infection and Clarithromycin resistance using Real-Time Polymerase Chain Reaction. European review for medical and pharmacological sciences. 2021 08; 25(15):5042-5046. doi: 10.26355/eurrev_202108_26461. [PMID: 34355376]
  • Keisuke Nakase, Mayu Nakanishi-Yamasaki, Kanji Harada, Juri Koizumi, Tetsuya Yamada, Hideaki Ikoshi, Hidemasa Nakaminami, Norihisa Noguchi. Antimicrobial activity and additive effect of the modified Gingyo-san with antimicrobials against Helicobacter pylori. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2021 Jul; 27(7):957-961. doi: 10.1016/j.jiac.2021.02.008. [PMID: 33602640]
  • Mohamed Sharaf, Muhammad Arif, Sohaib Khan, Mohnad Abdalla, Samah Shabana, Zhe Chi, Chenguang Liu. Co-delivery of hesperidin and clarithromycin in a nanostructured lipid carrier for the eradication of Helicobacter pylori in vitro. Bioorganic chemistry. 2021 07; 112(?):104896. doi: 10.1016/j.bioorg.2021.104896. [PMID: 33901764]
  • Man Xie, Qing Li, Bei Zhang, Qun Zhang, Qiu-Ju Tian, Hong Liu, Yun-Jin Zang, Wei Rao. Preliminary single-center experience of Helicobacter pylori eradication among the liver transplant recipients. Helicobacter. 2021 Jun; 26(3):e12791. doi: 10.1111/hel.12791. [PMID: 33600067]
  • Sara Abolghasemi, Shahnaz Sali, Arad Mobasher Aghdam, Mohammad Amin Shahrbaf. Anti-tuberculosis Induced Stevens-Johnson Syndrome Due to Misdiagnosis of Mycobacterium Abscessus Urinary Tract Infection as Tuberculosis. Iranian journal of kidney diseases. 2021 May; 15(3):235-237. doi: NULL. [PMID: 33994384]
  • Ahmed Aljishi, Marwan Jabr Alwazzeh, Mar Kristjansson. Pneumonia due to Mycobacterium cosmeticum in a renal transplant recipient. BMJ case reports. 2021 Mar; 14(3):. doi: 10.1136/bcr-2020-234800. [PMID: 33653829]
  • Jianglin Peng, Jiahua Guo, Yuan Lei, Jiezhang Mo, Haotian Sun, Jinxi Song. Integrative analyses of transcriptomics and metabolomics in Raphidocelis subcapitata treated with clarithromycin. Chemosphere. 2021 Mar; 266(?):128933. doi: 10.1016/j.chemosphere.2020.128933. [PMID: 33223212]
  • Soyoung Lee, Yujin Lee, Andrew HyoungJin Kim, Sumin Yoon, Jieon Lee, Sang Chun Ji, Seo Hyun Yoon, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho. Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects. Drug metabolism and pharmacokinetics. 2021 Feb; 36(?):100374. doi: 10.1016/j.dmpk.2020.12.001. [PMID: 33348239]
  • Xueping Huang, Yuan Liu, Zhihui Lin, Baihe Wu, Gaohui Nong, Yushan Chen, Yuping Lu, Xinhua Ji, Xiang Zhou, Biao Suo, Qiuzhao Chen, Jinqi Wei. Minimum inhibitory concentrations of commonly used antibiotics against Helicobacter Pylori: A multicenter study in South China. PloS one. 2021; 16(9):e0256225. doi: 10.1371/journal.pone.0256225. [PMID: 34473713]
  • Yao Chen, Hongxun Yuan, Hui Ye, Zongming Shi, Xin Deng, Xuezhi Zhang, Xikang Hou. Application of a semi-automatic, intensive follow-up for improving efficacy and adherence of Helicobacter pylori eradication therapy: A randomized controlled trial. MicrobiologyOpen. 2021 01; 10(1):e1172. doi: 10.1002/mbo3.1172. [PMID: 33650799]
  • Guoping Luo, Anqi Lin, Zhaoqiang Yang, Yujian Chen, Cuiying Mo. Computerized Tomography Image Feature under Convolutional Neural Network Algorithm Evaluated for Therapeutic Effect of Clarithromycin Combined with Salmeterol/Fluticasone on Chronic Obstructive Pulmonary Disease. Journal of healthcare engineering. 2021; 2021(?):8563181. doi: 10.1155/2021/8563181. [PMID: 34381586]
  • M A Gedikli, B Tuzun, A Aktas, K Sayin, H Ataseven. Are clarithromycin, azithromycin and their analogues effective in the treatment of COVID19?. Bratislavske lekarske listy. 2021; 122(2):101-110. doi: 10.4149/bll_2021_015. [PMID: 33502877]
  • Soonsil Hyun, Yoonhwa Choi, Doyeon Jo, Seolah Choo, Tae Woo Park, Su-Jin Park, Seoyeon Kim, Seonju Lee, Sohyun Park, Sun Mi Jin, Dae Hee Cheon, Wanki Yoo, Rekha Arya, Yong Pil Chong, Kyeong Kyu Kim, Yang Soo Kim, Yan Lee, Jaehoon Yu. Proline Hinged Amphipathic α-Helical Peptide Sensitizes Gram-Negative Bacteria to Various Gram-Positive Antibiotics. Journal of medicinal chemistry. 2020 12; 63(23):14937-14950. doi: 10.1021/acs.jmedchem.0c01506. [PMID: 33205989]
  • Shin-Ichiro Ogawa, Makiko Shimizu, Hiroshi Yamazaki. Modelled plasma concentrations of pemafibrate with co-administered typical cytochrome P450 inhibitors clopidogrel, fluconazole or clarithromycin predicted by physiologically based pharmacokinetic modelling in virtual populations. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Dec; 50(12):1413-1422. doi: 10.1080/00498254.2020.1793030. [PMID: 32628085]
  • Melodi Yusibova, Henrik Hasman, Philip Thomas Lanken Conradsen Clausen, Frank Imkamp, Karoline Wagner, Leif Percival Andersen. CRHP Finder, a webtool for the detection of clarithromycin resistance in Helicobacter pylori from whole-genome sequencing data. Helicobacter. 2020 Dec; 25(6):e12752. doi: 10.1111/hel.12752. [PMID: 32844531]
  • Yao Chen, Qingyi Liu, Fulian Hu, Jizheng Ma. Identifying the best regimen for primary eradication of Helicobacter pylori: analysis of 240 cases. MicrobiologyOpen. 2020 11; 9(11):e1120. doi: 10.1002/mbo3.1120. [PMID: 33026166]
  • Eui Hyun Jung, Choong-Min Lee, Ji-Yeong Byeon, Hyo-Bin Shin, Kyung-Yul Oh, Chang-Keun Cho, Chang Woo Lim, Choon-Gon Jang, Seok-Yong Lee, Yun Jeong Lee. Relationship between plasma exposure of zolpidem and CYP2D6 genotype in healthy Korean subjects. Archives of pharmacal research. 2020 Sep; 43(9):976-981. doi: 10.1007/s12272-020-01250-1. [PMID: 32661920]
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