Plumieride (BioDeep_00000003774)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


methyl (1S,4aS,7R,7aS)-4'-[(1S)-1-hydroxyethyl]-5'-oxo-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyspiro[4a,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-furan]-4-carboxylate

化学式: C21H26O12 (470.1424)
中文名称: 鸡蛋花甙
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 89.89%

Reviewed

Last reviewed on 2024-11-15.

Cite this Page

Plumieride. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/plumieride (retrieved 2024-12-25) (BioDeep RN: BioDeep_00000003774). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C1=CC2(C=CC3C2C(OC=C3C(=O)OC)OC4C(C(C(C(O4)CO)O)O)O)OC1=O)O
InChI: InChI=1S/C21H26O12/c1-8(23)10-5-21(33-18(10)28)4-3-9-11(17(27)29-2)7-30-19(13(9)21)32-20-16(26)15(25)14(24)12(6-22)31-20/h3-5,7-9,12-16,19-20,22-26H,6H2,1-2H3/t8-,9+,12+,13+,14+,15-,16+,19-,20-,21+/m0/s1

描述信息

Plumieride is a glycoside.

Plumieride has been reported in Plumeria rubra, Allamanda cathartica

Plumieride. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=511-89-7 (retrieved 2024-11-15) (CAS RN: 511-89-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

3 个代谢物同义名

Plumieride; Agoniadin; Plumieride



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

46 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 2 CAT, PTGS2
Peripheral membrane protein 1 PTGS2
Endoplasmic reticulum membrane 2 PTGES, PTGS2
Nucleus 1 MPO
cytosol 2 CAT, GPT
nucleoplasm 1 MPO
Cell membrane 1 TNF
Multi-pass membrane protein 1 PTGES
cell surface 1 TNF
lysosomal membrane 1 GAA
neuronal cell body 1 TNF
Lysosome 2 GAA, MPO
plasma membrane 2 GAA, TNF
Membrane 3 CAT, GAA, PTGES
caveola 1 PTGS2
extracellular exosome 5 AMY2A, CAT, GAA, GPT, MPO
Lysosome membrane 1 GAA
endoplasmic reticulum 1 PTGS2
extracellular space 6 AMY2A, IL2, IL4, IL6, MPO, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 1 PTGES
mitochondrion 1 CAT
protein-containing complex 2 CAT, PTGS2
intracellular membrane-bounded organelle 3 CAT, GAA, MPO
Microsome membrane 1 PTGS2
Secreted 4 GAA, IL2, IL4, IL6
extracellular region 8 AMY2A, CAT, GAA, IL2, IL4, IL6, MPO, TNF
mitochondrial matrix 1 CAT
external side of plasma membrane 1 TNF
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 1 PTGES
Membrane raft 1 TNF
focal adhesion 1 CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 MPO
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
phagocytic cup 1 TNF
tertiary granule membrane 1 GAA
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 IL6, PTGS2
azurophil granule membrane 1 GAA
azurophil granule lumen 1 MPO
nuclear envelope lumen 1 PTGES
phagocytic vesicle lumen 1 MPO
ficolin-1-rich granule membrane 1 GAA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
autolysosome lumen 1 GAA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Alana Shunnarah, Robin Tumlinson, Angela I Calderón. Natural Products with Potential for Nonhormonal Male Contraception. Journal of natural products. 2021 10; 84(10):2762-2774. doi: 10.1021/acs.jnatprod.1c00565. [PMID: 34633803]
  • Thaise Boeing, Priscila de Souza, Tiago José Bonomini, Luísa Nathália Bolda Mariano, Lincon Bordignon Somensi, Ruth Meri Lucinda, Angela Malheiros, Luísa Mota da Silva, Sérgio Faloni de Andrade. Antioxidant and anti-inflammatory effect of plumieride in dextran sulfate sodium-induced colitis in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Mar; 99(?):697-703. doi: 10.1016/j.biopha.2018.01.142. [PMID: 29710467]
  • Tiago J Bonomini, Iandra Holzmann, Liliani Carolini Thiesen, Eduarda Fratoni, Ana Flavia Fischer Muller, Ruth M Lucinda-Silva, Rosendo Augusto Yunes, Angela Malheiros, Ana Elisa Gonçalves, Ana Paula Dalmagro, Kathryn Ana Bortolini Simão da Silva, Márcia Maria de Souza, José Roberto Santin. Neuropharmacological and acute toxicological evaluation of ethanolic extract of Allamanda cathartica L. flowers and plumieride. Regulatory toxicology and pharmacology : RTP. 2017 Dec; 91(?):9-19. doi: 10.1016/j.yrtph.2017.10.005. [PMID: 28986178]
  • Sebastião de O Rebouças, Juliana da Silva, Ricardo S Bertoni, Natalia Decker, Marcela Silva Dos Santos, Raíssa R Rossatto, Dione S Corrêa, Alexandre B F Ferraz. Assessment of the genotoxic and mutagenic properties of Himatanthus articulatus bark extracts used as phytotherapeutic drug in the Amazon. Journal of ethnopharmacology. 2013 May; 147(2):474-80. doi: 10.1016/j.jep.2013.03.041. [PMID: 23528362]
  • R S Gupta, A K Bhatnager, Y C Joshi, R Sharma, A Sharma. Effects of plumieride, an iridoid on spermatogenesis in male albino rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2004 Feb; 11(2-3):169-74. doi: 10.1078/0944-7113-00346. [PMID: 15070168]
  • T N Tiwari, V B Pandey, N K Dubey. Plumieride from Allamanda cathartica as an antidermatophytic agent. Phytotherapy research : PTR. 2002 Jun; 16(4):393-4. doi: 10.1002/ptr.967. [PMID: 12112301]
  • G T Tan, J M Pezzuto, A D Kinghorn, S H Hughes. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Journal of natural products. 1991 Jan; 54(1):143-54. doi: 10.1021/np50073a012. [PMID: 1710653]