Willardiine (BioDeep_00000003191)

   

natural product


代谢物信息卡片


3-(Uracil-1-yl)-L-alanine

化学式: C7H9N3O4 (199.0593)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(lipidsearch) 30.7%

分子结构信息

SMILES: C1=CN(C(=O)NC1=O)CC(C(=O)O)N
InChI: InChI=1S/C7H9N3O4/c8-4(6(12)13)3-10-2-1-5(11)9-7(10)14/h1-2,4H,3,8H2,(H,12,13)(H,9,11,14)/t4-/m0/s1

描述信息

同义名列表

4 个代谢物同义名

Willardiine; 3-(Uracil-1-yl)-L-alanine; DL-Willardiine; 3-(Uracil-1-yl)-L-alanine



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 BDNF, CA3, SGTA
Endoplasmic reticulum membrane 1 GRIA1
Nucleus 1 SGTA
cytosol 3 CA3, GRIA1, SGTA
dendrite 5 BDNF, GRIA1, GRIA2, GRIA4, GRIK3
nucleoplasm 2 GRIK2, GRIK5
Cell membrane 9 GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1, GRIK2, GRIK3, GRIK5
Early endosome membrane 1 GRIA1
Multi-pass membrane protein 10 CACNA1I, GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1, GRIK2, GRIK3, GRIK5
Synapse 1 GRIA1
cell surface 2 CACNG2, GRIA1
dendritic shaft 1 GRIA1
glutamatergic synapse 5 CACNG2, GRIA1, GRID1, GRIK2, GRIK3
neuromuscular junction 1 GRIA1
neuronal cell body 3 GRIA1, GRIA2, GRIA4
postsynapse 1 GRIA2
presynaptic membrane 4 GRIK1, GRIK2, GRIK3, GRIK5
synaptic vesicle 1 BDNF
Presynapse 1 GRIA1
plasma membrane 12 CACNA1I, CACNG2, CSF2, GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1, GRIK2, GRIK3, GRIK5
synaptic vesicle membrane 1 GRIA1
terminal bouton 2 GRIK2, GRIK3
Membrane 10 BDNF, CACNA1I, GRIA1, GRIA2, GRIA4, GRIK2, GRIK3, GRIK5, SGTA, TBC1D8
axon 2 BDNF, GRIK3
extracellular exosome 1 GRID1
endoplasmic reticulum 2 GRIK2, GRIK5
extracellular space 2 BDNF, CSF2
perinuclear region of cytoplasm 1 BDNF
Schaffer collateral - CA1 synapse 1 CACNG2
intracellular membrane-bounded organelle 2 CSF2, GRIK1
postsynaptic density 3 GRIA1, GRIA2, GRIK2
Secreted 2 BDNF, CSF2
extracellular region 2 BDNF, CSF2
excitatory synapse 2 GRIA1, GRIA2
hippocampal mossy fiber to CA3 synapse 3 CACNG2, GRIK2, GRIK5
neuronal cell body membrane 1 GRIA1
external side of plasma membrane 2 GRIA1, GRIA2
Extracellular vesicle 1 GRIA4
dendritic spine 4 GRIA1, GRIA2, GRIA3, GRIA4
perikaryon 2 GRIK2, GRIK3
neuron spine 1 GRIA1
cell-cell junction 1 GRIA1
recycling endosome 1 GRIA1
postsynaptic membrane 8 GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1, GRIK2, GRIK3
presynaptic active zone membrane 1 GRIA1
GABA-ergic synapse 1 GRID1
Cell projection, dendritic spine 1 GRIA1
Postsynaptic cell membrane 9 GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1, GRIK2, GRIK3, GRIK5
dendrite cytoplasm 2 GRIK2, GRIK3
kainate selective glutamate receptor complex 4 GRIK1, GRIK2, GRIK3, GRIK5
mossy fiber rosette 1 GRIK2
cell projection 2 GRIK2, GRIK5
postsynaptic density, intracellular component 1 GRIA1
Recycling endosome membrane 1 GRIA1
AMPA glutamate receptor complex 5 CACNG2, GRIA1, GRIA2, GRIA3, GRIA4
Cell projection, dendrite 2 GRIA1, GRIA4
Presynaptic cell membrane 2 GRIK2, GRIK5
synaptic membrane 1 GRIA1
endoplasmic reticulum lumen 1 BDNF
voltage-gated calcium channel complex 2 CACNA1I, CACNG2
endocytic vesicle membrane 5 CACNG2, GRIA1, GRIA2, GRIA3, GRIA4
cerebellar mossy fiber 1 CACNG2
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GRIA1
postsynaptic density membrane 10 CACNG2, GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRIK1, GRIK2, GRIK3, GRIK5
postsynaptic endocytic zone 1 GRIA2
ER to Golgi transport vesicle membrane 1 GRIA1
parallel fiber to Purkinje cell synapse 1 GRIA3
Synapse, synaptosome 1 CACNG2
TRC complex 1 SGTA
somatodendritic compartment 1 CACNG2
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
dendritic spine membrane 1 GRIA1
asymmetric synapse 1 GRIA2
proximal dendrite 1 GRIA1
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
axonal spine 1 GRIA1
perisynaptic space 1 GRIA1


文献列表

  • Adak Nasiripourdori, Valérie Taly, Thomas Grutter, Antoine Taly. From toxins targeting ligand gated ion channels to therapeutic molecules. Toxins. 2011 03; 3(3):260-93. doi: 10.3390/toxins3030260. [PMID: 22069709]
  • T Fukushima, J Marshall, K Sakata, R Shingai. Calcium inhibits willardiine-induced responses in kainate receptor GluR6(Q)/KA-2. Neuroreport. 2001 Jan; 12(1):163-7. doi: 10.1097/00001756-200101220-00040. [PMID: 11201079]