3-Methyl-1-butylamine (BioDeep_00000002866)
Secondary id: BioDeep_00000864073, BioDeep_00001868089
human metabolite Endogenous
代谢物信息卡片
化学式: C5H13N (87.1048)
中文名称: 异戊胺
谱图信息:
最多检出来源 Homo sapiens(not specific) 3.41%
分子结构信息
SMILES: CC(C)CCN
InChI: InChI=1S/C5H13N/c1-5(2)3-4-6/h5H,3-4,6H2,1-2H3
描述信息
3-Methyl-1-butylamine, also known as isoamylamine or 3,3-dimethylpropylamine, belongs to the class of organic compounds known as monoalkylamines. These are organic compounds containing an primary aliphatic amine group. A primary aliphatic amine that is butan-1-amine carrying a methyl substituent at position 3. 3-Methyl-1-butylamine is an ammonia and unpleasant tasting compound. 3-methyl-1-butylamine has been detected, but not quantified, in several different foods, such as green vegetables, black elderberries, root vegetables, corns, and french plantains. This could make 3-methyl-1-butylamine a potential biomarker for the consumption of these foods.
3-Methyl-1-butylamine is widespread in fungi and higher plants e.g. apple, banana, wine grape, swede, rhubarb, porcini (Boletus edulis). 3-Methyl-1-butylamine is found in many foods, some of which are black elderberry, root vegetables, french plantain, and spinach.
KEIO_ID I039
同义名列表
29 个代谢物同义名
laquo gammaraquo -Isoamylamine; Isoamylamine carbonate (1:1); 3-Methyl-1-butanamine, 9ci; Isoamylamine hydrochloride; 3,3-Dimethyl-propylamine; 3,3-Dimethylpropylamine; 1-Amino-3-methylbutane; 3-Methyl-1-butylamine; 3-METHYLBUTAN-1-amine; 3-Methyl-1-butanamine; 3-Methyl-butylamine; Isobutylcarbylamine; gamma-Isoamylamine; Isoamylamine, reag; Monoisopentylamine; 3-Methylbutylamine; 3-Methylbutanamine; 1-Aminoisopentane; Monoisoamylamine; Isovalerylamine; g-Isoamylamine; Γ-isoamylamine; Isopentylamine; ISOAMYLAMINE; FEMA 3219; Leucamine; LEN; 3-Methylbutanamine; Isoamylamine
数据库引用编号
23 个数据库交叉引用编号
- ChEBI: CHEBI:43689
- KEGG: C02640
- PubChem: 7894
- HMDB: HMDB0031659
- Metlin: METLIN65805
- ChEMBL: CHEMBL42003
- KNApSAcK: C00050469
- foodb: FDB008319
- chemspider: 7606
- CAS: 107-85-7
- MoNA: KO003217
- MoNA: KO003219
- MoNA: KO003220
- MoNA: KO003221
- MoNA: KO003218
- PMhub: MS000006720
- PubChem: 5620
- PDB-CCD: LEN
- NIKKAJI: J95.661I
- RefMet: 3-Methyl-1-butylamine
- KNApSAcK: 43689
- LOTUS: LTS0224828
- wikidata: Q2835874
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 119431 - Hippospongia communis: 10.1515/BCHM2.1960.322.1.198
- 9606 - Homo sapiens: -
- 29760 - Vitis vinifera: 10.1021/JF00107A012
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yun Teng, Jingyao Mu, Fangyi Xu, Xiangcheng Zhang, Mukesh K Sriwastva, Qiaohong M Liu, Xiaohong Li, Chao Lei, Kumaran Sundaram, Xin Hu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Eric C Rouchka, Xiang Zhang, Jun Yan, Michael L Merchant, Huang-Ge Zhang. Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death.
Cell host & microbe.
2022 07; 30(7):944-960.e8. doi:
10.1016/j.chom.2022.05.005. [PMID: 35654045] - Takako Aboshi, Chiaki Iitsuka, Ivan Galis, Masayoshi Teraishi, Marina Kamo, Ayami Nishimura, Atsushi Ishihara, Naoki Mori, Tetsuya Murayama. Isopentylamine is a novel defence compound induced by insect feeding in rice.
Plant, cell & environment.
2021 01; 44(1):247-256. doi:
10.1111/pce.13902. [PMID: 33034373] - Yong-Ren Yen, Yu-Hsun Wang, Lina Wang, Lien-Cheng Chen, Fung-Jou Lu, Soo-Ray Wang. Novel Function of Isoamylamine Improves Survival in Endotoxemic Mice by Ameliorating Coagulopathy and Attenuating MMP-9 Expression Through p-ERK/p-p38 Signaling at Early Stage.
Shock (Augusta, Ga.).
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PloS one.
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Annals of the New York Academy of Sciences.
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Marine drugs.
2009; 7(1):1-8. doi:
10.3390/md7010001. [PMID: 19370166] - Elinor Scott, Francisc Peter, Johan Sanders. Biomass in the manufacture of industrial products--the use of proteins and amino acids.
Applied microbiology and biotechnology.
2007 Jun; 75(4):751-62. doi:
10.1007/s00253-007-0932-x. [PMID: 17387469] - Stephen D Liberles, Linda B Buck. A second class of chemosensory receptors in the olfactory epithelium.
Nature.
2006 Aug; 442(7103):645-50. doi:
10.1038/nature05066. [PMID: 16878137] - Simon R Bailey, Lisa M Katz, Yoel Berhane, Tim Samuels, Nicholas De Brauvere, Celia M Marr, Jonathan Elliott. Seasonal changes in plasma concentrations of cecum-derived amines in clinically normal ponies and ponies predisposed to laminitis.
American journal of veterinary research.
2003 Sep; 64(9):1132-8. doi:
10.2460/ajvr.2003.64.1132. [PMID: 13677391] - S R Bailey, A Rycroft, J Elliott. Production of amines in equine cecal contents in an in vitro model of carbohydrate overload.
Journal of animal science.
2002 Oct; 80(10):2656-62. doi:
10.2527/2002.80102656x. [PMID: 12413088] - S Bu, Y Kim, S Kim, M Lee. Effects of enzyme inducers and inhibitor on the pharmacokinetics of intravenous 2-(allylthio)pyrazine, a new chemoprotective agent, in rats.
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The Journal of experimental zoology.
1992 Oct; 264(1):42-5. doi:
10.1002/jez.1402640107. [PMID: 1447556] - K Nishimura, K Utsumi, M Yuhara, Y Fujitani, A Iritani. Identification of puberty-accelerating pheromones in male mouse urine.
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