Leucamine (BioDeep_00000864073)

Main id: BioDeep_00000002866

 


代谢物信息卡片


InChI=1\C5H13N\c1-5(2)3-4-6\h5H,3-4,6H2,1-2H

化学式: C5H13N (87.1048)
中文名称: 异戊胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)CCN
InChI: InChI=1S/C5H13N/c1-5(2)3-4-6/h5H,3-4,6H2,1-2H3



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 AIMP2, AOC3, AZIN2, UCMA
Nucleus 4 AIMP2, AZIN2, PDC, S100A8
autophagosome 1 MAP1LC3A
cytosol 5 AIMP2, AZIN2, MAP1LC3A, PDC, S100A8
dendrite 1 AZIN2
trans-Golgi network 1 AZIN2
Cell membrane 1 AOC3
Lipid-anchor 1 MAP1LC3A
cell surface 1 AOC3
glutamatergic synapse 1 MAP1LC3A
Golgi apparatus 1 AOC3
Golgi membrane 1 INS
Cytoplasm, cytosol 2 AIMP2, PDC
plasma membrane 2 AOC3, S100A8
Membrane 3 AIMP2, AOC3, AZIN2
axon 1 AZIN2
extracellular exosome 1 S100A8
endoplasmic reticulum 1 AOC3
extracellular space 2 INS, S100A8
perinuclear region of cytoplasm 1 AZIN2
mitochondrion 1 AZIN2
intracellular membrane-bounded organelle 1 MAP1LC3A
Secreted 1 INS
extracellular region 3 INS, S100A8, UCMA
photoreceptor inner segment 1 PDC
photoreceptor outer segment 1 PDC
Secreted, extracellular space, extracellular matrix 1 UCMA
perikaryon 1 AZIN2
cytoplasmic vesicle 1 AZIN2
Early endosome 1 AOC3
Single-pass type II membrane protein 1 AOC3
Cytoplasm, cytoskeleton 1 MAP1LC3A
microtubule 1 MAP1LC3A
cis-Golgi network 1 AZIN2
extracellular matrix 1 UCMA
collagen-containing extracellular matrix 1 S100A8
Late endosome 1 MAP1LC3A
Cytoplasmic vesicle, autophagosome membrane 1 MAP1LC3A
autophagosome membrane 1 MAP1LC3A
cytoskeleton 1 S100A8
Cell projection, cilium, photoreceptor outer segment 1 PDC
organelle membrane 1 MAP1LC3A
Endomembrane system 1 MAP1LC3A
endosome lumen 1 INS
microvillus 1 AOC3
intermediate filament cytoskeleton 1 S100A8
secretory granule lumen 2 INS, S100A8
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
transport vesicle 2 AZIN2, INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 AZIN2, INS
endoplasmic reticulum-Golgi intermediate compartment 1 AZIN2
[Isoform 2]: Nucleus 1 PDC
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
Golgi apparatus, cis-Golgi network 1 AZIN2
Autolysosome 1 MAP1LC3A
calprotectin complex 1 S100A8
granular vesicle 1 AZIN2


文献列表

  • Yun Teng, Jingyao Mu, Fangyi Xu, Xiangcheng Zhang, Mukesh K Sriwastva, Qiaohong M Liu, Xiaohong Li, Chao Lei, Kumaran Sundaram, Xin Hu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Eric C Rouchka, Xiang Zhang, Jun Yan, Michael L Merchant, Huang-Ge Zhang. Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death. Cell host & microbe. 2022 07; 30(7):944-960.e8. doi: 10.1016/j.chom.2022.05.005. [PMID: 35654045]
  • Takako Aboshi, Chiaki Iitsuka, Ivan Galis, Masayoshi Teraishi, Marina Kamo, Ayami Nishimura, Atsushi Ishihara, Naoki Mori, Tetsuya Murayama. Isopentylamine is a novel defence compound induced by insect feeding in rice. Plant, cell & environment. 2021 01; 44(1):247-256. doi: 10.1111/pce.13902. [PMID: 33034373]
  • Yong-Ren Yen, Yu-Hsun Wang, Lina Wang, Lien-Cheng Chen, Fung-Jou Lu, Soo-Ray Wang. Novel Function of Isoamylamine Improves Survival in Endotoxemic Mice by Ameliorating Coagulopathy and Attenuating MMP-9 Expression Through p-ERK/p-p38 Signaling at Early Stage. Shock (Augusta, Ga.). 2017 06; 47(6):772-779. doi: 10.1097/shk.0000000000000786. [PMID: 27841846]
  • Kelly A Flanagan, William Webb, Lisa Stowers. Analysis of male pheromones that accelerate female reproductive organ development. PloS one. 2011 Feb; 6(2):e16660. doi: 10.1371/journal.pone.0016660. [PMID: 21347429]
  • Stephen D Liberles. Trace amine-associated receptors are olfactory receptors in vertebrates. Annals of the New York Academy of Sciences. 2009 Jul; 1170(?):168-72. doi: 10.1111/j.1749-6632.2009.04014.x. [PMID: 19686131]
  • Khozirah Shaari, Kee Cheng Ling, Zalilawati Mat Rashid, Tan Pei Jean, Faridah Abas, Salahudin Mohd Raof, Zurina Zainal, Nordin Hj Lajis, Habsah Mohamad, Abdul Manaf Ali. Cytotoxic aaptamines from Malaysian Aaptos aaptos. Marine drugs. 2009; 7(1):1-8. doi: 10.3390/md7010001. [PMID: 19370166]
  • Elinor Scott, Francisc Peter, Johan Sanders. Biomass in the manufacture of industrial products--the use of proteins and amino acids. Applied microbiology and biotechnology. 2007 Jun; 75(4):751-62. doi: 10.1007/s00253-007-0932-x. [PMID: 17387469]
  • Stephen D Liberles, Linda B Buck. A second class of chemosensory receptors in the olfactory epithelium. Nature. 2006 Aug; 442(7103):645-50. doi: 10.1038/nature05066. [PMID: 16878137]
  • Simon R Bailey, Lisa M Katz, Yoel Berhane, Tim Samuels, Nicholas De Brauvere, Celia M Marr, Jonathan Elliott. Seasonal changes in plasma concentrations of cecum-derived amines in clinically normal ponies and ponies predisposed to laminitis. American journal of veterinary research. 2003 Sep; 64(9):1132-8. doi: 10.2460/ajvr.2003.64.1132. [PMID: 13677391]
  • S R Bailey, A Rycroft, J Elliott. Production of amines in equine cecal contents in an in vitro model of carbohydrate overload. Journal of animal science. 2002 Oct; 80(10):2656-62. doi: 10.2527/2002.80102656x. [PMID: 12413088]
  • S Bu, Y Kim, S Kim, M Lee. Effects of enzyme inducers and inhibitor on the pharmacokinetics of intravenous 2-(allylthio)pyrazine, a new chemoprotective agent, in rats. Biopharmaceutics & drug disposition. 2000 May; 21(4):157-64. doi: 10.1002/1099-081x(200005)21:4<157::aid-bdd226>3.0.co;2-c. [PMID: 11180194]
  • M A Price, J G Vandenbergh. Analysis of puberty-accelerating pheromones. The Journal of experimental zoology. 1992 Oct; 264(1):42-5. doi: 10.1002/jez.1402640107. [PMID: 1447556]
  • K Nishimura, K Utsumi, M Yuhara, Y Fujitani, A Iritani. Identification of puberty-accelerating pheromones in male mouse urine. The Journal of experimental zoology. 1989 Sep; 251(3):300-5. doi: 10.1002/jez.1402510306. [PMID: 2769207]
  • P P Giannousis, P A Bartlett. Phosphorus amino acid analogues as inhibitors of leucine aminopeptidase. Journal of medicinal chemistry. 1987 Sep; 30(9):1603-9. doi: 10.1021/jm00392a014. [PMID: 3625708]